scholarly journals Comparative evaluation of isoflurane and sevoflurane in avian patients

2021 ◽  
pp. 1067-1073
Author(s):  
R. R. Anjana ◽  
P. V. Parikh ◽  
J. K. Mahla ◽  
D. N. Kelawala ◽  
K. P. Patel ◽  
...  
Keyword(s):  
Induction Time ◽  
Recovery Time ◽  
Muscle Relaxation ◽  
Complete Recovery ◽  
Versus Group ◽  
Quality Of Recovery ◽  
Anesthetic Agents ◽  
Group I ◽  
Significant Difference

Background and Aim: Literature comparing the use of isoflurane and sevoflurane inhalation anesthetic agents in birds is scarce. This study aimed to evaluate the comparison of isoflurane and sevoflurane during induction, maintenance, and recovery of anesthesia in avian patients. Materials and Methods: In this study, 24 injured avian patients (n=24) were selected randomly and divided into four groups during kite flying festival. In the present study, isoflurane and sevoflurane were used as induction and maintenance anesthetic agents, with and without butorphanol tartrate premedication agent in all the birds. Different physiological parameters were evaluated, namely, cloacal temperature (°F), heart rate (beats/min), respiratory rate (breaths/min), and SpO2 (%) were recorded at 0, 10, 20 min, and at recovery time. The quality of anesthesia was assessed on the basis of induction time, quality of induction, production of analgesia, muscle relaxation, body reflexes, recovery time, quality of recovery, sitting, standing, and complete recovery time (CRT). Results: The mean±standard error value of induction time was 230.00±32.55, 280.00±25.29, 180.00±21.90, and 260.00±36.87 s, respectively, in Groups I, II, III, and IV. The feather plucking, pharyngeal, and toe pinching reflexes were noticed, when the birds were passing through the light plane of anesthesia during induction. Comparison of cloacal temperature at the time of recovery between Group-I versus Group-III revealed a significant difference (p<0.05). Comparison of mean respiratory rates at the time of recovery between Group-II versus Group-IV revealed a significant difference (p<0.05). Excellent quality of recovery was observed in all the groups of anesthetic protocols. Sitting, standing, and CRT were observed shortest in avian patients maintained with sevoflurane as compared to isoflurane. Conclusion: The quality of induction of anesthesia was rapid in avian patients when induced with sevoflurane as compared to isoflurane. Rapid onset of induction and recovery of anesthesia were found with sevoflurane followed by isoflurane. Induction and maintenance of anesthesia in avian patients with sevoflurane resulted in the lowest time required for sitting, standing, and CRT.

scholarly journals Potential use of dexmedetomidine for different levels of sedation, analgesia and anaesthesia in dogs

2013 ◽  
Vol 58 (No. 2) ◽  
pp. 87-95 ◽  
Author(s):  
Amarpal ◽  
RA Ahmad ◽  
P. Kinjavdekar ◽  
HP Aithal ◽  
AM Pawde ◽  
...  
Keyword(s):  
Heart Rate ◽  
Recovery Time ◽  
Deep Sedation ◽  
Muscle Relaxation ◽  
Complete Recovery ◽  
Group Iii ◽  
Group I ◽  
Righting Reflex ◽  
Sedation And Analgesia ◽  
Different Levels

A combination of drugs may be preferred over the use of a single agent to induce deep sedation. A synergistic interaction between the drugs reduces the dose requirements of the drugs thereby minimising the unwanted side effects associated with each drug and improving recovery. The present study was undertaken to evaluate the suitability of dexmedetomidine and dexmedetomidine in combination with midazolam-fentanyl or midazolam-fentanyl-ketamine for different levels of sedation, analgesia and anaesthesia in dogs. In a prospective, blinded, randomised clinical trial, 12 mixed breed dogs were divided into three groups. Animals of Group I were injected with dexmedetomidine 20 &mu;g/kg. Animals of Group II received 20 &mu;g/kg dexmedetomidine + 0.2 mg/kg midazolam + 4 &mu;g/kg fentanyl and animals of Group III were administered with 20 &mu;g/kg dexmedetomidine + 0.2 mg/kg midazolam + 4 &mu;g/kg fentanyl + 10 mg/kgketamine. All the drugs were given simultaneously via the intramuscular route. Jaw relaxation, palpebral reflex, pedal reflex and response to intubation were recorded and graded on a numerical scale. Values of heart rate, respiratory rate, rectal temperature and mean arterial pressure were recorded at baseline and then at predetermined intervals up to 120 min. Onset of sedation time, onset of recumbency time, time to return of righting reflex, standing recovery time and complete recovery time were recorded. Maximal muscle relaxation, sedation and analgesia were observed in animals of Group III, which was followed in decreasing order by Groups II and I. Heart rate decreased significantly (P &lt; 0.05) after administration of drugs in Groups I and II but a significant (P &lt; 0.05) increase was recorded in Group III. Respiratory rate decreased significantly (P &lt; 0.05) in all the groups. Rectal temperature decreased non-significantly in all the groups. Mean arterial pressure initially increased significantly (P &lt; 0.01) in Groups I and III followed by a decrease in Group I, but in Group III it remained above the base line. In Group II, MAP decreased throughout the study period. Onset of sedation time and onset of recumbency time were significantly (P &lt; 0.05) shorter in Group III as compared to Group I. Time to return of righting reflex, standing recovery time and complete recovery time did not differ significantly between the groups. It is concluded that dexmedetomidine provides a reliable moderate sedation and analgesia. Addition of midazolam and fentanyl enhances sedation, analgesia and muscle relaxation induced by dexmedetomidine. Addition of ketamine produced deep sedation and complete anaesthesia with lesser cardiopulmonary depression. Thus, dexmedetomidine can be used safely in combination with midazolam, fentanyl and ketamine for different levels of sedation, analgesia and anaesthesia in dogs. &nbsp;

Analgesic and adjunct actions of nalbuphine hydrochloride in xylazine or xylazine and acepromazine premedicated horses

2015 ◽  
Author(s):  
Harish Kulkarni ◽  
B. Justin William ◽  
Ravi Sundar George ◽  
T. A. Kannan
Keyword(s):  
Body Weight ◽  
Dose Rate ◽  
Muscle Relaxation ◽  
Group Iii ◽  
Quality Of Recovery ◽  
Group I ◽  
The Mean ◽  
Group Ii ◽  
Mean Time

The study was conducted in eighteen clinical cases of horses for diagnostic and surgical procedures requiring general anaesthesia were randomly divided into three groups, group I, group II and group III, each consisting of six cases. All the horses were premedicated with glycopyrrolate at the dose rate of 0.02 mg/kg body weight, intravenously. Horses in Group I and Group II were administered xylazine hydrochloride at the dose rate of 1.10 mg/kg body weight intravenously, whereas in Group III at the dose rate of 0.50 mg/kg body weight intravenously. In Group III, acepromazine was injected after xylazine administration, at the dose rate of 0.02mg/kg body weight, intravenously. Before induction of anaesthesia, nalbuphine hydrochloride was administered for Group II and Group III at the dose rate of 0.75 mg/kg body weight intravenously. Ketamine hydrochloride was administered intravenously to induce anaesthesia at the dose rate of 2.20 mg/kg body weight and maintained with 0.50 mg/kg body weight in required cases to maintain for duration of 15 ± 1.04 minutes. The mean time for induction in group I, group II and group III were 1.78 ± 0.27, 1.73 ± 0.10 and 1.85 ± 0.28 minutes respectively. The mean total number of additional doses of ketamine for standard duration of 15 ± 1.04 minutes surgery required in group I, group II and group III were 5.00 ± 0.36, 1.66 ± 0.33 and 2.00 ± 0.36 respectively. The quality of induction was 100 per cent smooth in group III, 83.33 per cent smooth and 16.67 per cent rough in group II and 66.66 per cent smooth and 33.34 per cent rough in group I. The quality of analgesia in group I, group II and group III were 2.83 ± 0.47, 1.83 ± 0.30 and 1.33 ± 0.21 respectively. The quality of muscle relaxation in group I, group II and group III were 3.16 ± 0.30, 1.50 ± 0.22 and 1.33 ± 0.21 respectively. The mean time for recovery in group I, group II and group III were 23.00 ± 1.52, 33.00 ± 0.93 and 41.98 ± 1.32 minutes respectively. The mean number of attempts for unassisted standing in group I, group II and group III were 6.66 ± 0.71, 5.00 ± 0.57 and 5.00 ± 0.36 respectively. The quality of recovery was 83.33 per cent smooth and 16.67 per cent rough in group III, 66.66 per cent smooth and 33.34 per cent rough in group II and 50.00 per cent smooth and 50.00 per cent rough in group I. None of the animals in any groups showed any intra and post operative complication.

scholarly journals Impact of hemodialysis on the wellbeing of chronic kidney diseases patients: a pre-post analysis

2020 ◽  
Vol 27 (1) ◽  
Author(s):  
Um-e-Kalsoom ◽  
Sabiha Khan ◽  
Israr Ahmad
Keyword(s):  
Quality Of Life ◽  
Social Support ◽  
Perceived Social Support ◽  
Kidney Diseases ◽  
Chronic Kidney Diseases ◽  
Group I ◽  
Significant Difference ◽  
Group Ii ◽  
The Impact

Abstract Background Hemodialysis may have serious psychological impact upon patients suffering from chronic kidney diseases. The aim of the present study is to investigate the impact of hemodialysis on the wellbeing of individuals with chronic kidney diseases (CKD). Result A sample consists of (N = 100) CKD patients referred from neurology ward of Leady Reading Hospital Peshawar. Data was collected from both male (50%) and female (50%) in 2017. Participants were divided into two groups on the basis of pre-set criteria. In group I, individuals with 4–5 stage of CKD referred first time for dialysis treatment were recruited. Group II comprised of CKD patients with 1–3 stage. Demographic data sheet, Pakistan Anxiety and Depression, WHO Quality of Life scale, and Perceived Social support scale (PSS) were used to test the hypotheses. Paired sample t test was use to see the difference between pre- and post-analysis of depression, anxiety, QOL, and PSS in group I (experimental group). Results suggests significant difference on depression (p > .001), anxiety (p > .001), and QOL (p > .001), while no significant difference was reported on perceived social support (p <.673). Findings also indicate no significant difference between group I and group II on QOL depression, anxiety, and PSS. Conclusion The findings concluded that patients under hemodialysis treatment suffered from depression, anxiety, and poor quality of life.

Effectiveness analysis of the new method of antireflux surgery in patients with hiatal hernia

2020 ◽  
Vol 26 (4) ◽  
pp. 50-55
Author(s):  
A.R. Stasyshyn ◽  
◽  
A.A. Hurayevskyy ◽  
Yu.Y. Holyk ◽  
◽  
...  
Keyword(s):  
Quality Of Life ◽  
Los Angeles ◽  
Hiatal Hernia ◽  
Antireflux Surgery ◽  
New Method ◽  
Life Questionnaire ◽  
Post Surgery ◽  
Group I ◽  
Significant Difference

Aim. To analyze the effectiveness of a new method of antireflux surgery in patients with hiatal hernia. Materials and Methods. The results of treatment of 157 patients with hiatal hernia from 2016 to 2020 are analyzed. The patients were divided into 3 groups: group I, N=59, underwent laparoscopic antireflux operation modified by the authors (Patent of Ukraine № 59772); group II (N=77), underwent laparoscopic Nissen fundoplication; and group III (N=21) - laparoscopic Toupet fundoplication. Results and Discussion. At 36 months post-surgery follow-up, there was a statistically significant difference in favor of group I on the average scores of the visual analog scale for reflux symptoms, dysphagia and extraesophageal symptoms; the average quality of life questionnaire scores; the average DeMeester index; distribution of the patients by satisfaction; distribution of the patients by degree of reflux esophagitis according to the Los Angeles classification; and distribution by gas-bloat syndrome. Conclusions. Clinical application of the developed new method of laparoscopic surgery for hiatal hernia reduces the number of relapses and complications after surgery, and improves the quality of life of patients. Key words: hiatal hernia, antireflux surgery, new methods of treatment

scholarly journals Comparitive evaluation of different concentrations of alcohol in ultrasound guided coeliac plexus neurolysis for pain relief in upper abdominal malignancies

2021 ◽  
Vol 8 (4) ◽  
pp. 492-500
Author(s):  
Manish Kumar Singh ◽  
Pragya Verma ◽  
Sarita Singh ◽  
Gyan P Singh ◽  
Hemlata Verma
Keyword(s):  
Quality Of Life ◽  
Morphine Consumption ◽  
Rescue Analgesia ◽  
Vas Score ◽  
Group I ◽  
Significant Difference ◽  
The Mean ◽  
Group Ii ◽  
Upper Abdominal

Patients suffering from advanced upper abdominal malignancies have pain as predominant symptom affects their quality of life and survival. USG guided coeliac plexus neurolysis become benevolence in these patients on part of their pain management and quality of life improvement. To compare the efficacy of USG guided coeliac plexus neurolysis for pain relief in upper abdominal malignancies by using different concentration of alcohol (50% vs 75%).This Prospective, comparative, randomised double blinded study was conducted during Sep 2019 – Aug 2020 at our tertiary care centre. Total 60 cases were taken as per following inclusion and exclusion criteria and randomly divided into 2 groups i.e. 30 each group, we compare Visual Analogue Scale (VAS) score, quality of life (QOL) and need of rescue analgesia profile between the groups to know the efficacy of USG guided coeliac plexus block. In our study, we observed that the baseline mean VAS score in group I was 8.26±0.78 while in group II was 8.03±0.76. No significant difference was found in mean VAS score at this time between the groups (p=0.24). The baseline mean QOL score in group-I was 77.46±3.40 while for the cases of group II the mean QOL score was 77.36±3.33. No significant difference was found in mean QOL score at baseline between the groups (p=0.90). The baseline mean morphine consumption in group-I was 113.33±39.24 mg while for the cases of group-II the mean morphine consumption was 120.33±38.37mg. No significant difference was found in mean morphine consumption at this time between the groups (p=0.48).Both groups having 50% alcohol and 75% alcohol decreases the VAS score from baseline in patients having upper abdominal malignancies along with QOL and dosages of rescue analgesia whereas no significant difference in VAS score in patients of both groups.

Comparison of two intramuscular sedation protocols on sedation, recovery and ease of venipuncture for cats undergoing blood donation

2018 ◽  
Vol 21 (2) ◽  
pp. 95-102 ◽  
Author(s):  
Rebecca C Reader ◽  
Bruce A Barton ◽  
Amanda L Abelson
Keyword(s):  
Blood Donation ◽  
Muscle Relaxation ◽  
Blood Collection ◽  
Blood Draw ◽  
Suitable Alternative ◽  
Treatment Groups ◽  
Sedation Protocol ◽  
Significant Difference ◽  
Lateral Recumbency

Objectives The aim of this study was to compare the quality of sedation and recovery, and ease of venipuncture following sedation for feline blood donation using two intramuscular (IM) sedation protocols: alfaxalone/butorphanol (AB) and dexmedetomidine/butorphanol (DB). Methods This was an experimental randomized, blinded, crossover study. Ten client-owned healthy cats were recruited to participate in the study. Cats were sedated with AB (alfaxalone 2 mg/kg and butorphanol 0.2 mg/kg) for one donation and DB (dexmedetomidine 10 μg/kg and butorphanol 0.2 mg/kg) for another. Reaction to injection, quality of sedation and quality of recovery were assessed by a blinded observer. Time to lateral recumbency, number of venipuncture attempts, time required for blood collection and time to return to sternal recumbency were recorded. Cats were monitored for evidence of gastrointestinal distress. Each donation consisted of a maximum of 53 ml whole blood drawn over 3–22 mins. Donors received 100 ml subcutaneous lactated Ringer’s solution in recovery. Owners, unaware of sedation protocol, were asked to complete a questionnaire evaluating their cat’s behavior following sedation. Results IM injections were well tolerated by both treatment groups. There was no significant difference between treatment groups in sedation scores for posture ( P = 0.30) or behavior ( P = 0.06). Cats sedated with DB had significantly higher muscle relaxation scores ( P = 0.03) compared with AB. There was no significant difference between treatment groups in time to lateral recumbency ( P = 0.12), number of venipuncture attempts ( P = 0.91) and time for blood draw ( P = 0.29). There was no difference in quality of recoveries between treatment groups based on simple descriptive scores ( P = 0.18) and owner evaluation 24 h following sedation. One cat vomited following administration of DB. Conclusions and relevance Alfaxalone is a suitable alternative to dexmedetomidine when combined with butorphanol and used as part of an IM sedation protocol for cats undergoing blood donation.

scholarly journals INTERVENSI PROGRESSIVE MUSCLE RELAXATION LEBIH MENURUNKAN TEKANAN DARAH DARI PADA SLOW STROKE BACK MASSAGE PADA PASIEN HIPERTENSI DERAJAT I YANG MENGONSUMSI OBAT ANTI HIPERTENSI DI BADUNG

2019 ◽  
Author(s):  
Ni Komang Ayu Juni Antari ◽  
Alex Pangkahila ◽  
Muh. Ali Imron ◽  
I Putu Adiartha Griadhi ◽  
Luh Made Indah Sri Handari Adiputra ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Physical Exercise ◽  
Muscle Relaxation ◽  
Progressive Muscle Relaxation ◽  
Control Group ◽  
Relaxation Techniques ◽  
Group I ◽  
Significant Difference ◽  
Group 2 ◽  
Back Massage

ABTSRACT Introduction: Physical exercise as anticipate of hypertension along with nutrition and medicines. One of physical exercise that can be applicated here is relaxation techniques which is showed positive impact in decreased blood pressure. Objective: Determine the difference between PMR intervention with SSBM intervention to reduce blood pressure for grade I hypertension patients whose consumed anti-hypertension medicine in badung regency. Methods: Experimental method Pre and post-test control group design and used 24 subjects, divided in to 2 groups, in which the experimental group I (n=12) received progressive muscle relaxation (PMR) while the treatment group 2 (n=12) received slow stroke back massage (SSBM). Intervention is given 3 times a week for 4 weeks. This study was using simple random sampling. Blood pressure was measured by sphygmomanometer and stethoscope. Result: Independent Sample T-test showed there was significant difference between Group 1 and Group 2 which (p<0.05) for systolic and diastolic blood pressure. Conclusion: Progressive muscle relaxation intervention decrease blood pressure more than slow stroke back massage intervention in patients grade I hypertension whose consumed anti-hypertension medicine in Badung Regency.Keywords: progressive muscle relaxation, slow stroke back massage, grade I hypertension, blood pressure

scholarly journals Comparison of the Effect of Passive and Active Recovery, and Self-Myofascial Release Exercises on Lactate Removal and Total Quality of Recovery

2018 ◽  
Vol 6 (9a) ◽  
pp. 33 ◽  
Author(s):  
İlbilge Özsu ◽  
Baris Gurol ◽  
Cem Kurt
Keyword(s):  
Strenuous Exercise ◽  
Total Quality ◽  
Active Recovery ◽  
Wingate Anaerobic Test ◽  
Subsequent Performance ◽  
Myofascial Release ◽  
Quality Of Recovery ◽  
Significant Difference ◽  
Exercise Induced

Recovery from exercise-induced fatigue is crucial for subsequent performance. Self-myofascial release (SMR) using a foam roller is an alternative to active recovery (AR). This study aims to compare the effects of passive recovery (PR), AR, and SMR on blood lactate [La-] removal and total quality of recovery (TQR). Twenty-two well trained male athletes (age: 22.6±2.9 years) underwent three testing sessions conducted 72 hours apart but at the same time of each day in a randomized order. After determining resting [La-] and heart rate (HR), the subjects completed a Wingate anaerobic test (WAnT), triggering muscular fatigue. HR and [La-] were measured threeminutes after the WAnT, following which the subjects underwent one of the three different recovery interventions over 15 minutes: PR (lying supine), AR (cycling at 40% of the estimated maximum HR of the respective subject), and SMR (using foam roller on lower extremity muscles). After each recovery intervention, [La-], HR, and TQR were measured. There was no statistically significant difference in [La-] and HR values obtained before the WAnT test (p=0.368, p=0.691, respectively) and right after the WAnT test (0.264, p=0.629) Both AR and SMR were more effective than PR for [La-] removal and obtaining a higher TQR (p<0.001). However, SMR and AR were not superior to one another for blood [La-] removal (p>0.05). In contrast, a significantly higher TQR was observed with SMR than AR and PR (p<0.001). Athletes can apply AR or SMR to recover from strenuous exercise. SMR can be an alternative to PR and AR as a recovery tool.

scholarly journals Sociodemographic profile and quality of life of active older adults belonging to a physical exercise program and sedentary elderly, linked to a basic health unit

10.3823/2346 ◽  
2017 ◽  
Vol 10 ◽  
Author(s):  
Francisco Dimitre Rodrigo Pereira Santos ◽  
Simony Fabíola Lopes Nunes ◽  
Marluce Alves Coutinho ◽  
Leila Rute Oliveira Gurgel do Amaral ◽  
Floriacy Stabnow Santos ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Physical Exercise ◽  
Elderly People ◽  
Life Questionnaire ◽  
Cross Sectional ◽  
Group I ◽  
Significant Difference ◽  
Sociodemographic Profile ◽  
Group Ii

Objective: To identify the sociodemographic profile and to compare the quality of life of elderly people who practice physical exercises in a group with sedentary elderly. Methods: This is a cross-sectional study with a quantitative approach, composed of two groups: Group I consisted of 50 elderly people practicing physical exercise in a group; and Group II composed of 50 sedentary elderlies. Data were collected through two questionnaires; one questionnaire focused on the sociodemographic data survey and the SF-36 quality of life questionnaire. The data were analyzed by the BioEstat 5.0 program using the Z-Test. Results: Group I had better scores in the domains, limitations due to physical aspects and general health, in the other domains, group II had better scores. Factor that can be attributed to the modality of the physical exercise performed by group I that was in the group I and by the form of the allocation of the sample. Conclusion: The women were mostly in group I, and both groups were comprised of seniors over 61 years old, widowers and retirees. Statistically, only the general state of health showed a significant difference between the two groups.

scholarly journals A comparative study of hemodynamic changes and adverse effects of intrathecal bupivacaine with fentanyl and intrathecal bupivacaine with clonidine in infra-umbilical abdominal and lower limb surgery

2019 ◽  
Vol 6 (11) ◽  
pp. 4048
Author(s):  
Krishna Prasad G. V. ◽  
Vipin Jaishree Sharma
Keyword(s):  
Adverse Effects ◽  
Lower Limb ◽  
Analgesic Effects ◽  
Anesthetic Agents ◽  
Group I ◽  
Significant Difference ◽  
Lower Limb Surgery ◽  
Hemodynamic Profile ◽  
Group Ii ◽  
Intrathecal Clonidine

Background: Adjuvants prolong the action of intrathecal local anesthetic agents. They have shown to have significant analgesic effects in the postoperative period much after the regression of the sensory and motor blockade. Our objective of the current study was to compared the hemodynamic profile and adverse effects (nausea, pruritus, sedation and respiratory depression) in two groups of adult patients undergoing infra-umbilical and lower limb surgery under spinal anaesthesia using either intrathecal clonidine or intrathecal fentanyl as an adjuvant to intrathecal bupivacaine (0.5% heavy).Methods: This randomized, prospective and observational study was undertaken in the Department of Anaesthesiology and Critical Care, 5 Airforce Hospital, Kanpur from the period of January 2014 to February 2016 on 120 patients fulfilling the inclusion criteria. Study patients were randomly allocated to the two groups Group I: Cases who received intrathecal 0.5% heavy bupivacaine (2.5 ml) + fentanyl (50 mcg/ml) (0.5 ml) (n=60 patients) and Group II: cases who received intrathecal 0.5% heavy bupivacaine (2.5 ml) + clonidine (60 mcg/ml) (0.5 ml) (n=60 patients).Results: Mean age of patients in Group I and Group II was 42.60±5.93 and 42.03±7.16 years, respectively. Mean BMI of patients in Group I and Group II was 22.0±1.92 and 21.54±2.14 kg/m2, respectively. Comparison of baseline hemodynamic parameters (heart rate (bpm), mean arterial pressure (mmhg), respiratory rate (/min) and oxygen saturation (%) did not show a significant difference between two groups.Conclusions: With respect to the side effects like nausea and pruritus, these are significantly more in fentanyl group as compared to clonidine group.

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