scholarly journals THE DEVELOPMENT OF TECHNOLOGY FOR OBTAINING OF TENESTROL SUBSTANCE OF ESTROGENIC AC-TION FROM THE AERIAL PARTS OF FERULA TENUISECTA

2019 ◽  
pp. 269-276
Author(s):  
Мунирахон (Munirakhon) Ахматхон кизи (Ahmatkhon kizi) Маматханова (Mamatkhanova) ◽  
Равшанжон (Ravshanzhon) Муратджанович (Muratdzhanovich) Халилов (Khalilov) ◽  
Любовь (Lyubov') Дмитриевна (Dmitrievna) Котенко (Kotenko) ◽  
Ахматхон (Ahmatkhon) Умарханович (Umaralievich) Маматханов (Mamatkhanov)
Keyword(s):  
Aerial Part ◽  
Raw Materials ◽  
Water Solution ◽  
Weight Ratio ◽  
Volume Ratio ◽  
Raw Material ◽  
Alcohol Extract ◽  
Aerial Parts ◽  
Green Coloration ◽  
Water Alcohol

Extraction of the sum of esters of the sesquiterpene alcohols from the aerial part of Ferula tenuisecta and purification of obtained extract were studied, allowing in following to get the final substance without green coloration. It was determined the optimum adsorbent – actuated coal and its amount for removing the green coloration of water-alcohol extract from used raw materials. It was found that for the purification of the bottoms of water-alcohol extract, five-fold treatment with extractive petrol in a volume ratio of water solution – solvent 2:1 is necessary, and for extraction esters from a purified water solution – three-fold extraction with ethyl acetate in a volume ratio of water solution – solvent 2:1. It was used a filler to effective drying the substance of Tenestrol. The microcrystalline cellulose in a weight ratio from 1:8 to 1:10 to the raw material was chosen as the optimum filler. Technology for obtain of substance of esters of sesquiterpene alcohols with estrogenic action from the aerial part of Ferula tenuisecta was developed and called “Tenestrol”. From this technology substance "Tenestrol" with yield of 3.8% by weight of the raw material is obtained, which contains not less 20% of the esters.

scholarly journals End-of-Life Alternatives of Glass Reinforced Polyester Boat Hulls Compared by LCA

2018 ◽  
Vol 27 (4) ◽  
pp. 096369351802700 ◽  
Author(s):  
Mehmet Önal ◽  
Gökdeniz Neşer
Keyword(s):  
End Of Life ◽  
Environmental Impacts ◽  
Raw Materials ◽  
Weight Ratio ◽  
Cost Effective ◽  
Raw Material ◽  
Photochemical Oxidation ◽  
Human Toxicity ◽  
Vacuum Infusion ◽  
Infusion Method

Glass reinforced polyester (GRP), as a thermoset polymer composites, dominates boat building industry with its several advantages such as high strength/weight ratio, cohesiveness, good resistance to environment. However, proper recovering and recycling of GRP boats is became a current environmental requirement that should be met by the related industry. In this study, to propose in a cost effective and environmentally friendly way, Life Cycle Assessment (LCA) has been carried out for six scenarios include two moulding methods (namely Hand Lay-up Method, HLM and Vacuum Infusion Method, VIM) and three End-of-Life (EoL) alternatives(namely Extruding, Incineration and Landfill) for a recreational boat's GRP hulls. A case study from raw materials purchasing phase to disposal/recycling stages has been established taking 11 m length GRP boat hull as the functional unit. Analysis show that in the production phase, the impacts are mainly due to the use of energy (electricity), transport and raw material manufacture. Largest differences between the methods considered (HLM and VIM) can be observed in the factors of marine aquatic ecotoxicity and eutrophication while the closest ones are abiotic depletion, ozon layer depletion and photochemical oxidation. The environmental impact of VIM is much higher than HLM due to its higher energy consumption while vacuum infusion method has lower risk than hand lay-up method in terms of occupational health by using less raw material (resin) in a closed mold. In the comparison of the three EoL techniques, the mechanical way of recycling (granule extruding) shows better environmental impacts except terrestrial ecotoxicity, photochemical oxidation and acidification. Among the EoL alternatives, landfill has the highest environmental impacts except ‘global warming potential’ and ‘human toxicity’ which are the highest in extrusion. The main cause of the impacts of landfill is the transportation needs between the EoL boats and the licenced landfill site. Although it has the higher impact on human toxicity, incineration is the second cleaner alternative of EoL techniques considered in this study. In fact that the similar trend has been observed both in production and EoL phases of the boat. It is obvious that using much more renewable energy mix and greener transportation alternative can reduce the overall impact of the all phases considerably.

scholarly journals Investigation of the process of production of crafted beer with spicy and aromatic raw materials

10.5219/1183 ◽  
2019 ◽  
Vol 13 (1) ◽  
pp. 806-814
Author(s):  
Marija Zheplinska ◽  
Mikhailo Mushtruk ◽  
Volodymyr Vasyliv ◽  
Olena Deviatko
Keyword(s):  
Cost Effectiveness ◽  
Physicochemical Parameters ◽  
Raw Materials ◽  
Scientific Work ◽  
Alcohol Concentration ◽  
Raw Material ◽  
Volumetric Fraction ◽  
Craft Beer ◽  
The Cost ◽  
Water Alcohol

This scientific work demonstrates the stages of the process of inspiring the spicy aromatic raw materials of Badian, which is added to the craft beer in the process of its digestion. In addition, the work shows an analysis of the composition of spicy aromatic raw materials which will be used as an additive. The research proves the rational quantity and concentration of alcoholic spiro-aromatic raw materials for beer and determines the effect of alcoholic spiro-aromatic raw materials on beer indices. We have clarified the organoleptic and physicochemical parameters of beer with spicy aromatic raw materials Badian and composition based on infusions of Badian and cinnamon. As a result, we received water-alcohol infusions of spicy aromatic raw materials and developed new types of beer on their basis. On the basis of the conducted studies, the regression equation of the dependence of the content of actual dry substances and the volumetric fraction of alcohol from the change in the amount of spray-aromatic raw material and alcohol concentration in the alcohol-alcoholic infusion of spin-aromatic raw materials was obtained. In addition, we conducted calculations on the cost-effectiveness of adding these types of spiced aromatic raw materials to beer.

Preparation and Properties of MgAl2O4-CaAl12O19 High Temperature Composite

2012 ◽  
Vol 512-515 ◽  
pp. 617-620
Author(s):  
Yong Hong Wang ◽  
Yan Gai Liu ◽  
Tao Yang ◽  
Zhao Hui Huang ◽  
Ming Hao Fang
Keyword(s):  
Phase Composition ◽  
High Temperature ◽  
Reaction Temperature ◽  
Bending Strength ◽  
Raw Materials ◽  
Weight Ratio ◽  
Raw Material ◽  
Reaction Conditions ◽  
Optimum Reaction ◽  
Industrial Alumina

The utilization of lightweight refractories plays an important role in reducing the energy consumption of industrial furnaces. In this paper, MgAl2O4-CaA112O19 high temperature composite was synthesized via solid state reaction using magnesite, dolomite and industrial alumina as raw materials. The influences of raw materials and reaction temperature on phase compositions and microstructure of the composite were investigated by XRD and SEM，respectively. The parameters to prepare MgAl2O4-CaA112O19 high temperature composite were optimized. The results show that the optimum reaction conditions for synthesizing MgAl2O4-CaA112O19 composite is the CA6/MA weight ratio of 2:3, and the reaction temperature of 1500°C for 4h. The CaA112O19 crystals showed laminated or plate-like structure, and the MgAl2O4 showed spherical morphology. The reaction temperature had little effect on the phase compositions of MA-CA6 composite in this experiment. The content of Al2O3 in the raw material affected the phase composition of MA-CA6 composite.With the increase of the CaA112O19 amount, the bending strength of the composite decreased.

scholarly journals Esterification of Glycerol with Acetic Acid in Bioadditive Triacetin with Fe2O3/Activated Carbon Catalyst

2020 ◽  
Vol 849 ◽  
pp. 125-129
Author(s):  
Zahrul Mufrodi ◽  
Shinta Amelia
Keyword(s):  
Gas Chromatography ◽  
Acetic Acid ◽  
Reaction Time ◽  
Catalyst Concentration ◽  
Raw Materials ◽  
Volume Ratio ◽  
Raw Material ◽  
Biodiesel Production ◽  
Carbon Catalyst ◽  
Mass Spectometry

Esterification and transesterification processes for biodiesel production generate glycerol which is possible to be converted into triacetin. It is an actractive bioadditive for increasing octane number of fuel. The production of this bioadditive in a biodiesel plant also increases the revenue as raw material comes from biodiesel process production as by-product.This study examines the effects of catalyst concentration and temperature on triacetin production using glycerol from esterification process and acetic acid at volume ratio of 1:3 as raw materials. An activated charcoal as catalyst is activated with sulfuric acid at concentration of 2% and 3% (w/w). The esterification temperatures are varied at 90 and 100°C and the reaction time is set for 3 hours. The samples are taken frequently at certain interval times of 15, 30, and 60 minutes for chemical analysis using Gas Chromatography Mass Spectometry. It is observed that using 2% and 3% (w/w) of catalysts at 90°C and 60 minutes reaction time converts 41.037% and 57.441% of glycerol respectively.

scholarly journals DEVELOPMENT OF TECHNOLOGY FOR PRODUCTION OF SUBSTANCE SILECBINE ON THE BASIS OF EC-DYSTEROIDS OF THE AERIAL PARTS OF SILENE BRAHUICA

2021 ◽  
pp. 319-327
Author(s):  
Ravshanjon Muratjanovich Khalilov ◽  
Mohira Rakhimovna Yakubova
Keyword(s):  
Particle Size ◽  
Microcrystalline Cellulose ◽  
Water Solution ◽  
Liquid Extraction ◽  
Raw Material ◽  
Process Temperature ◽  
Mass Ratio ◽  
Aerial Parts ◽  
Liquid Liquid Extraction ◽  
Plant Substances

The process extraction of ecdysterone from the aerial parts of Silene brahuica was studied. On the basis results research, the following extraction conditions were established: extractant – 90% ethanol, particle size of raw material – no more than 5 mm and process temperature – 20–30 °C. A five-fold extraction of ecdysterone from the aerial parts of Silene brahuica is proposed. To purify of the extract, a sequential liquid-liquid extraction is proposed, according to which the concentrated extract is diluted with water and treated three times with extraction petrol to remove hydrophobic impurities, then extracted six times with butanol to remove hydrophilic impurities. For effective drying of the silekbin substance, a filler was used, as which microcrystalline cellulose was selected in a mass ratio of 1 : 2 to the dry residue of the dried water solution. The technology of obtaining the substance of the adaptogenic and immunostimulating drug "Silekbin" from the aerial parts of Silene brahuica, which is tested on semi-industrial installations of the Pilot production of the Institute of the Chemistry of Plant Substances, has been developed.

scholarly journals THE DEVELOPMENT AND VALIDATION OF THE METHOD TO QUANTIFY THE AMOUNT OF PHENOLIC ACIDS IN AERIAL PARTS OF ZIZIPHORA CLINOPODIOIDES LAM.

2019 ◽  
pp. 161-168 ◽  
Author(s):  
Valeriya Yur'yevna Andreeva ◽  
Galina Il'inichna Kalinkina ◽  
Valeriya Vladimirovna Li
Keyword(s):  
Quantitative Determination ◽  
Phenolic Acids ◽  
Aerial Part ◽  
Raw Material ◽  
Alcoholic Extract ◽  
Extraction Temperature ◽  
Aerial Parts ◽  
Highly Sensitive ◽  
Development And Validation

Development and validation of method for quantitative determination of the amount of phenolic acids in the aerial part of the Ziziphora clinopodioides Lam. Objective: to develop and conduct a validation assessment of the method for determining the content of the amount of phenolic acids in the Ziziphora clinopodioides. The method of quantification of phenolic acids equivalent to chlorogenic acid by direct spectrophotometry in aerial parts of the Ziziphora clinopodioides has been developed based on the study of the absorption spectrum of an aqueous-alcoholic extract. The influence of the following factors on the yield of phenolic acids was studied: the nature of the extractant, the ratio of raw material: extractant, the degree of particle fineness, the extraction multiplicity, the extraction temperature; their optimum values were established. The method of quantitative determination of the amount of phenolic acids in the aerial part of the Ziziphora clinopodioides is validated; it has been established that the proposed method is highly sensitive, correct, reproducible and suitable for use in an analytical laboratory based on the data obtained.

TECHNOLOGICAL ASPECTS OF APPLICATION OF THE PHYTOSORBENT WITH NANOTUBES IN THE PROCESS OF ADSORPTIVE OIL PURIFICATION

2021 ◽  
pp. 59-66
Author(s):  
L. Krichkovskaya ◽  
Essam Elnaggar ◽  
V. Dubonosov
Keyword(s):  
Raw Materials ◽  
Water Solution ◽  
Low Cost ◽  
Agricultural Waste ◽  
Quality Parameters ◽  
Raw Material ◽  
Effect Of Temperature ◽  
Plant Raw Materials ◽  
Fractal Clusters ◽  
Technological Stage

In the present article importance of adsorptive purification of vegetable oils is shown as the most responsible technological stage. Insufficiency of scientific developments in the scope of domestic sorbents in Ukraine is pointed out. The phytosorbent with nanotubes from sunflower peel improving some quality parameters of non-refined sunflower and soybean oils to standard values for refined oils has been offered. Some literature data on the main characteristics of a number of sorption materials (carbonaceous, natural, fibrous, and sorbents obtained from agricultural waste - Corylus avellana Lambert nuts) as a result of heat treatment are analyzed. The main sorption properties are considered; dignity; limitations. The effect of temperature on the productivity of pyrolysis of plant raw materials and the properties of the resulting carbonizates in the temperature range 150-600 °C was investigated. The duration of exposure of materials at the final temperature of the process in all experiments was the same and amounted to 1 h. Analysis of the experimental data allows us to conclude that temperature is the main factor affecting the process of carbonization of the initial plant material. Regardless of the pyrolysis atmosphere, the yield of the product from plant raw materials decreases with a significant increase in temperature. At present, the main raw material for the industrial production of adsorbents is in many studies organic substances - wood, fossil coal, peat, remnants of the processing of agricultural raw materials due to their low cost and large amount. Solving the problem of creating sorbents based on plant raw materials with the inclusion of hydrated fullerenes in their composition solved the problem of creating sorbents and environmental problems, since the waste did not always find a useful application. Concentration of water solution of hydrated C60, fast C60FWS, є molecular-coloidal systems and spherical fractal clusters, structural unit of which is micro-hydrophilic, high-hydrophilic supramolecular complex, molecules can be folded to fit into ) 24-hydration of fullerene C60 (C60HyFn). The hydrated cultivation is set in its own well-ordered, structurally heterogeneous watery middle, in which the directness and kinetics of chemical processes are seen in such, that it is necessary to be washed in order to clean.

Ultrasonic-Assisted Extraction of Total Flavonoids and Lactones from Ginkgo Biloba Powder

2013 ◽  
Vol 641-642 ◽  
pp. 867-870
Author(s):  
Jing Xiang Cong ◽  
Shao Yan Wang ◽  
Wei Zhang ◽  
Xiao Dan Tang
Keyword(s):  
Ginkgo Biloba ◽  
Raw Materials ◽  
Water Solution ◽  
Ultrasonic Extraction ◽  
Raw Material ◽  
Orthogonal Experimental Design ◽  
Total Flavonoids ◽  
Optimal Conditions ◽  
Assisted Extraction ◽  
Ultrasonic Assisted

This article aims to study the extraction conditions of the total flavonoids and lactones from the ginkgo biloba powder. First, the influencing factors and levels for the extraction were determined by the single factor method, and then the optimum extraction conditions were optimized by orthogonal experimental design. The results showed that the optimal conditions for ultrasonic extraction of the total flavonoids were as follows: 2mg cellulase and 0.1g raw material (ginkgo biloba powder) were dissolved in 10ml water solution. The pH of the solvent was 4.5 adjusted with hydrochloric acid. The materials were extracted in ultrasound bath at 55°C for 40min. The optimal conditions for ultrasonic extraction of the total lactones were as follows: 7mg cellulase and 0.1g raw material were dissolved in 10ml water solution with pH 4.9. The raw materials were extracted at 50°C for 35min. Under the optimum conditions, the peak area contents were nearly 90% and 58% for total flavonoids and lactones, respectively.

scholarly journals Chromato-mass spectroscopy of tinctures of Valeriana officinalis aerial part

2021 ◽  
Vol 14 (1) ◽  
pp. 29-38
Author(s):  
V. M. Odyntsova ◽  
V. I. Kokitko ◽  
V. H. Korniievska ◽  
Yu. I. Korniievskyi ◽  
Ye. O. Karpun
Keyword(s):  
Aerial Part ◽  
Raw Materials ◽  
Antioxidant Properties ◽  
Experimental Studies ◽  
Acid Ethyl Ester ◽  
Quinic Acid ◽  
Component Composition ◽  
Biologically Active ◽  
Raw Material ◽  
Valeriana Officinalis

Underground Valerian roots (Vаlеrіаnае radix) are officinal raw materials. More than 1000 compounds were detected in Valeriana officinalis L. s.l., of which no less than 500 natural substances of organic and inorganic origin were identified, among them – carbohydrates, amino acids, lipids, vitamins, enzymes, phenolic compounds, essential oil, iridoids, alkaloids, steroids. The aerial part of Valerian is a source of various flavonoids with pronounced antioxidant properties and specific pharmacotherapeutic activity. The aim of the research is to determine, by means of gas chromatography, component composition of Valerian tinctures, made of the aerial part of V. tuberosa L., V. stolonifera Czern (Kantserivska balka, Zaporizhzhia region, Ukraine) and V. officinalis L. (Łódź, Bydgoszcz, Poland). Materials and methods. Tincture samples of the aerial part of wild species V. tuberosa L., V. stolonifera Czern (Kantserivska balka, Zaporizhzhia region), and V. officinalis L. (the experimental site of ZSMU; Łódź and Bydgoszcz in Poland) were selected for experimental studies according to the traditional production recipe for making tinctures (1 : 5). Component composition of the tinctures was studied using a 7890B gas chromatograph with a 5977B mass spectrometer detector. Results. By means of chromato-mass spectrometry, component composition of the Valerian tinctures has been identified, namely: in the tincture prepared from the aerial part of V. officinalis (Łódź, Poland) 54 components have been identified, V. tuberosa – 50; V. stolonifera – 46 and V. officinalis (Bydgoszcz, Poland) – 30. The chromatogram analysis of four Valerian tinctures helped to identify 118 components, 5 of which were present in all studied tinctures; 12 components were present in three tinctures; 22 components have been found in two tinctures. It should be noted that 10 components have been found in the tinctures in large quantities, their content ranging from 10.91 % to 30.02 %. Conclusions. Analyzing the obtained data of the GC, it can be seen that Valerian tinctures differ both in quantitative and qualitative composition. From the aerial part of Valeriana officinalis, prepared in Łódź and Bydgoszcz in Poland, 17 components coincide. In the tinctures, prepared from herbs collected in Ukraine, 10 components coincide. The highest content of Butanoic acid, 3-methyl – from 4.01 % to 16.78 %; 9,12,15-Octadecatrienoic acid, ethyl ester, (Z,Z,Z)- – from 0.47 % to 7.09 %; Dihydroxyacetone – from 0.37 % to 5.69 % and Quinic acid – from 0.30 % to 4.66 % in all four tinctures by peak areas and retention time should be marked. In three tinctures Cyclododecane, 1,5,9-tris(acetoxy)- has been identified in amount of 30.56 % to 14.56 %. The obtained results confirm the expediency of using the aerial part of Valeriana officinalis as raw material with a large commodity yield and various contents of biologically active substances for further pharmacognostic researches for the purpose of creation of new medicines and phytopreparations

scholarly journals Investigation of Walnut Herbal Drug Raw Material

2019 ◽  
Vol 8 (4) ◽  
pp. 38-46
Author(s):  
N. V. Chebyshev ◽  
A. V. Strelyaeva ◽  
D. I. Lezhava ◽  
A. N. Luferov ◽  
N. V. Bobkova ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Medicinal Plant ◽  
Raw Materials ◽  
Juglans Regia ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Raw Material ◽  
Alcohol Extract ◽  
Plant Raw Materials ◽  
Active Substances

Introduction. Walnut (Juglans regia L.) is a medicinal plant containing a large number of biologically active substances. A number of authors propose to use walnut leaves as medicinal raw materials, in which juglone, flavonoids, tannins, ascorbic acid and other substances are identified. Currently, a standardization technique for this type of raw material has been developed and proposed. However, the medicinal plant walnut can be a source of other types of raw materials, such as milky-waxed walnuts, walnut bark, and walnut partitions. These types of medicinal raw materials contain a large number of biologically active substances and have a great potential for pharmacological activity. Therefore, the study with the subsequent standardization of medicinal plant material of walnut fruits in the stage of milk-wax ripeness and walnut bark is relevant.Aim. The aim of the study is to study the external signs, microscopy of raw walnut bark and walnut fruit in the stage of milky-wax ripeness and chemical composition of alcohol extract from these types of raw materials.Materials and methods. Chromato-mass spectrometry and TLC were used in the work.Results and discussion. When describing external signs and microscopy, diagnostic signs of both whole and crushed raw materials, and powder of walnut bark, and fruits of walnut in the stage of milky-wax ripeness were revealed. Alcohol extract obtained from medicinal plant raw materials walnut bark is a clear brown liquid. Alcohol extract obtained from medicinal plant raw materials of walnut fruit at the stage of milky-wax ripeness is a transparent, green-brown liquid with a fragrant odor.Conclusion. Gallic acid was identified by TLC in walnut bark. Chromato-mass spectrometry in alcohol extraction from the fruit of walnut in the stage of milky-wax maturity was able to identify 17 compounds belonging to different classes of biologically active substances. Sugars, flavonoids, coumarin phenolic compounds, organic acids were identified. In alcoholic extraction from the bark of a walnut, marker compounds have been determined, the combination of which makes it possible to quickly identify this type of raw material using chromatography-mass spectrometry. 

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