scholarly journals FEATURES OF THE COMPOSITION MACRO ELEMENTS AND TRACE ELEMENTS OF THE EXTRACT OF ALFREDIA CERNUA (L.) CASS., POSSESSING PSYCHOTROPIC EFFECT

2019 ◽  
pp. 191-198
Author(s):  
Inessa Vladimirovna Shilova ◽  
Natal'ya Vladimirovna Baranovskaja ◽  
Rustam Niyazovich Mustafin ◽  
Nikolay Innokent'yevich Suslov
Keyword(s):  
Trace Elements ◽  
Aerial Part ◽  
Organometallic Compounds ◽  
Ethanol Extract ◽  
Biologically Active ◽  
Cobalt Chromium ◽  
Macro Elements ◽  
Ultra Trace ◽  
Pharmacologically Active ◽  
Active Substances

The 95% ethanol extract of Alfredia drooping Alfredia cernua (L.) Cass. (Asteraceae) aerial part exhibits pronounced antidepressant, nootropic and anxiolytic activity. The aim of the work was the qualitative and quantitative analysis of macro-, trace and ultra trace elements of the pharmacologically active extract of the aerial part of the plant. The study of the elemental composition of the extract was performed after ashing using instrumental neutron activation analysis with irradiation with thermal neutrons. The study found 26 elements, of which eight are (conditionally) essential, two macro elements and four trace elements. The obtained results indicate the prevalence of Alfredia cernua of calcium, zinc, sodium, strontium, bromine, as well as iron, barium, cobalt, chromium and lanthanum in the pharmacologically active extract. The extract concentrates a specific group of elements (zinc, cobalt, thorium, hafnium, bromine, chromium, lutetium, lanthanum, strontium, samarium) in comparison with the feedstock, which can be explained by the formation of strong organometallic compounds and chelate complexes. Macro-, trace and ultra trace elements can have a significant impact on metabolic processes, nervous, immune, endocrine, cardiovascular systems, they are an integral part of enzymes, give other biologically active substances an easily digestible form and potentiate their effects.

scholarly journals Quantitative analysis of biologically active substances and the investigation of antioxidant and antimicrobial activities of some extracts of Osage orange fruits

Pharmacia ◽  
2021 ◽  
Vol 68 (4) ◽  
pp. 731-739
Author(s):  
Ani Slavik Dadayan ◽  
Lala Ashot Stepanyan ◽  
Tatevik Hovhannes Sargsyan ◽  
Anahit Mkhitar Hovhannisyan ◽  
Slavik Arshak Dadayan
Keyword(s):  
Antimicrobial Activity ◽  
Ethanol Extract ◽  
Antimicrobial Activities ◽  
The Body ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Osage Orange ◽  
Wide Range ◽  
Pharmacologically Active ◽  
Active Substances

Biologically active substances, the antioxidant and antimicrobial activity of aqueous, 70% ethylate and ethyl acetate extracts of fruits of maclura orange (Osage Orange), a representative of the Moraceae genus growing in the Ararat region of Armenia have been studied. It is found that plant extracts are rich in a wide range of pharmacologically active substances, in particular, tannins, flavonoids, organic acids, vitamins, anthocyanins, micro- and microelements, etc. Based on the investigations performed, extracts of maclura orange can be recommended as a source of biologically active substances (BAS), as well as a preventive and corrective agent in deficiency or imbalance of macro- and microelements in tissue and cellular structures in various pathological processes in the body. An ethanol extract of maclura fruits exhibits the antimicrobial activity against Bacillus subtilis 1820, E. Coli 5002, Serratia marcescens 5251 and Staphylococcus aureus ATCC-6538 strains. Maclura extracts can be used as an environmentally friendly source of antioxidants against early aging.

scholarly journals EFFECTIVENESS OF MICROELEMENTS IN THE FORMATION OF MECHANISMS OF PROTECTION OF THE BODY UNDER THE INFLUENCE OF ENVIRONMENTAL STRESS FACTORS

2021 ◽  
Vol 22 (1) ◽  
pp. 61-67
Author(s):  
V. O. Velichko
Keyword(s):  
Trace Elements ◽  
Immune Status ◽  
The Body ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Stress Factors ◽  
Enzymatic System ◽  
Antioxidant Protection ◽  
The Impact ◽  
Active Substances

Analysis of literature data and the results of our own research show that even with intensive rearing of animals with the use of balanced feeding and keeping them in accordance with the technology - it is almost impossible to avoid stress. And especially, excessive man-made load on agroecosystems also has a negative impact on animal life. Factors that cause a decrease in immune status and the emergence of immune pathology in animals include: industrial technology of animal husbandry, chemicalization in crop and livestock production, man-made pressure, dietary imbalance in nutrients and biologically active substances. This increases the impact on the body of heavy metals, which displace nutrients from body tissues, in particular trace elements and replace them in metabolic processes, which is a potential prerequisite for the development of oxidative stress. The mechanism of development of stress reaction of an organism is closely connected with activity of POL (lipid peroxidation) and depression of antioxidant potential. Under these conditions, the ability of the organism to mobilize protective and adaptive capabilities in response to the action of negative factors becomes especially important. Keeping productive animals in adverse conditions, unbalanced feeding are components of immobilization stress, which reduces their productivity, affects reproductive function, metabolic and functional disorders, reducing nonspecific and specific resistance of the organism (Fedoruk & Kravtsiv, 2003; Velychko, 2008; Velychko, 2011). Under conditions of man-caused load on the environment, respectively, and animals – it is promising to develop effective methods for regulating the activity of the enzymatic system of antioxidant protection with the help of biologically active substances, in particular trace elements. The results of research confirm that this has a positive effect on the formation of productive and adaptive properties of animals. The system of antioxidant protection is a necessary part of non-specific reactions of the organism, a component of the processes of its adaptation to environmental conditions, a component of normal life, a factor in maintaining homeostasis. Widespread immunodeficiency and elucidation of the main links of their pathogenesis have exacerbated the problem of regulating disorders of the immune system. Therefore, knowledge of the patterns of formation of the immune status of animals, especially in the early postnatal period, is important in the development of methods for the correction of immunodeficiency, antioxidant protection.

scholarly journals Chemical Composition and Content of Biologically Active Substances Found in Cotinus coggygria, Dactylorhiza maculata, Platanthera chlorantha Growing in Various Territories

Plants ◽  
2021 ◽  
Vol 10 (12) ◽  
pp. 2806
Author(s):  
Stanislav Sukhikh ◽  
Lyudmila Asyakina ◽  
Maxim Korobenkov ◽  
Liubov Skrypnik ◽  
Artem Pungin ◽  
...  
Keyword(s):  
Trace Elements ◽  
Capillary Electrophoresis ◽  
Medicinal Plants ◽  
Feed Additives ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Livestock Products ◽  
Cotinus Coggygria ◽  
Active Substances

Medicinal plants (Cotinus coggygria, Dactylorhiza maculata, Platanthera chlorantha) growing in various territories (Kaliningrad, Moscow, and Minsk regions) were the objects of research. This paper presents a study of the chemical composition of these plants. To analyze the qualitative and quantitative composition of biologically active substances, the method of high-performance liquid chromatography was used. Atomic absorption spectrometry was used to study the content of trace elements. The content of organic acids and vitamins was determined by capillary electrophoresis using the Kapel-105/105M capillary electrophoresis system with high negative polarity. Extracts of medicinal plants were obtained on a Soxhlet apparatus using 70% ethanol as an extractant. It was found that among the biologically active substances in the plants under discussion, hyperoside, rutin (C. coggygria), Ferulic acid and Gallic acid (D. maculata), triene hydrocarbon (3,7-Dimethyl-1,3,6-octatriene), unsaturated alcohol (3,7-Dimethyl-2,6-octadien-1-ol), and benzyl acetate (P. chlorantha) prevailed. Samples of these medicinal plants contained trace elements (phosphorus, potassium, calcium, sodium, magnesium, and sulfur) and many aliphatic organic acids (succinic acid, benzoic acid, fumaric acid, citric acid, oxalic acid, and tartaric acid). The largest amount of biologically active substances and secondary metabolites of the studied plants from the Eastern Baltic is associated with climatic and ecological differences from other regions. The composition of these plants determines the potential of their use in feed additives for livestock and poultry as part of measures to improve the quality of livestock products. The use of medicinal plants for the production of feed additives is relevant in terms of improving regional economies, as well as improving the quality of life and nation’s health by providing ecologically clean livestock products.

ECDYSTEROIDS AND FLAVONOIDS OF SILENE GRAEFFERI

2021 ◽  
pp. 175-182
Author(s):  
Elena Sergeyevna Filonenko ◽  
Larisa Nikolayevna Zibareva
Keyword(s):  
Aerial Part ◽  
Western Siberia ◽  
Botanical Garden ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
General Tendency ◽  
Vegetative Development ◽  
Promising Source ◽  
First Time ◽  
Active Substances

In this paper Silene graefferi Guss. is recommended for the first time as a promising source of flavonoids and is a well-known producer of ecdysteroids. This perennial species is adapted to the conditions of Western Siberia and has been successfully cultivated in the Siberian Botanical garden of TSU since 2015. It was interesting to study the composition and features of accumulation of biologically active substances during the growth and development of S. graefferi. It was shown that 20-hydroxyecdysone and polypodine B are present in the aerial and underground parts of introduced in culture S. graefferi plants during the entire vegetative development. An unidentified ecdysteroid was detected in the aerial part at the beginning of the vegetation and in the roots during the flowering phase. During vegetative development, common flavonoids and characteristic ones at different periods of plant development were found. The phase of maximum accumulation of ecdysteroids and flavonoids of S. graefferi is the beginning of vegetation, and the minimum is flowering. In the age dynamics the highest levels of biologically active substances in plants were noted at 2 and 3 years of life, then there is a general tendency to decrease with the age of the plant. From the aerial part of S. graefferi, 20-hydroxyecdysone, polypodine B and vitexin were isolated and identified by HPLC.

Research biologically active substances Atragene speciose Weinm.

2002 ◽  
Vol 1 (2) ◽  
pp. 55-59
Author(s):  
I. V. Shilova
Keyword(s):  
Oleanolic Acid ◽  
Pharmacological Activity ◽  
Triterpene Glycosides ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Active Fraction ◽  
Overground Part ◽  
Pharmacologically Active ◽  
Active Substances ◽  
Nootropic Effect

From the overground part of Atragene speciosa Weinm. family Ranunculaceae, we obtained a fraction possessing a marked nootropic effect from which 3,4-dihydroxyphenylethanol-2, its 2-O-β-D-glucopyranoside, and a sum of glycosides of dihydroxybutane acid were isolated. In addition to the foregoing substances, in the pharmacologically active fraction we revealed the presence of triterpene glycosides (whose sapogenins are hederagenine and oleanolic acid), aminoacids and microelements. For the frist time the obtained data about the biologically active substances and their pharmacological activity give us the possibility of development of a new phytopreparation with the nootropic effect on the basis of Atragene speciose Weinm.

scholarly journals Organoleptic characteristics and nutritional value of roasted peanuts from the chain of hotel and restaurant complexes in Kiev region

2021 ◽  
Vol 23 (96) ◽  
pp. 15-18
Author(s):  
L. Korol-Bezpala ◽  
S. Merzlov ◽  
V. Marshalok ◽  
H. Merzlova ◽  
Y. Shurchkova ◽  
...  
Keyword(s):  
Trace Elements ◽  
Human Health ◽  
Nutritional Value ◽  
Feed Additives ◽  
The Body ◽  
Biologically Active ◽  
State Research ◽  
Organoleptic Characteristics ◽  
Organoleptic Parameters ◽  
Active Substances

Foods must contain all the nutrients necessary to maintain human health, development and life. These components include protein, fats, carbohydrates, vitamins, minerals and other biologically active substances, which must be in sufficient quantity and ensure the proper functioning of the body. One such food that contains significant amounts of nutrients is peanuts. Peanuts are a source of protein, carbohydrates, fats, fiber, trace elements and vitamins. The nutrients of the product are easily absorbed. The article presents the results of a study of the nutritional value of roasted salted peanuts of various manufacturers, which are used for consumption in hotel and restaurant complexes in the Kiev region. The studies were carried out in the laboratory of the State Research Control Institute of Veterinary Drugs and Feed Additives (Lviv). Nutritional value was determined according to different methods, which are intended for each indicator, and also used statistical methods. According to the research results, it was revealed that the content of moisture, protein, fat and fiber in peanuts Big Bo, Felix Peanuts and Cossack Slava ranges, respectively, in the range from 0.73 to 1.37 %, from 26.3 to 26.9, from 46.01 to 48.6 g/100 g of product and 3.56 to 3.92 %. According to organoleptic parameters, prototypes of peanuts from different manufacturers meet the standard requirements. Promising research is the study of trace elements in roasted salted peanuts from various manufacturers.

Prospects for application sapropel in feeding of cows

2020 ◽  
pp. 54-60
Author(s):  
L. Yarmots ◽  
G. Yarmots ◽  
A. Belenkaya ◽  
M. Smyshlyaeva
Keyword(s):  
Trace Elements ◽  
Raw Materials ◽  
Positive Influence ◽  
Biologically Active ◽  
Control Group ◽  
Milk Productivity ◽  
Productivity Indicators ◽  
Experimental Group ◽  
Active Substances ◽  
Effective Source

Numerous studies have shown that sapropel is an effective source of macro-and microelements, as well as biologically active substances. There are about 3 million lakes on the territory of Russia, where sapropel reserves are estimated at 250 billion tons. There are 497 lakes on the territory of the Tyumen region, the estimated reserves of sapropel in them are 1398,7 million tons. The Tyumen region is a biogeochemical province for all normalized trace elements. Biologically active compounds obtained from natural raw materials, including normalized trace elements in organic form are the most promising and safe. Under the inviroments of the Tyumen region, such natural raw materials can be sapropels. The study of the effectiveness of the use of sapropels and their influence on the metabolism and milk productivity of cattle is an urgent topic. The purpose of the research was to study the influence of sapropel lake Nepryak on milk productivity indicators and the biochemical composition of the blood of cows. For the experiment 3 groups of cows have been formed (a control group and two experimental ones) based on the principle of pairs of analogs. Cows of the 1st experimental group have been got in the ration of 300 g of sapropel per head/day, 2nd experimental – 500 g/head/day. Cows of the control group did not receive sapropel in the ration. It has been found as the result of research that the use of sapropel lake Nepryak in feeding of cows in doses of 300 and 500 g/head/day had the positive influence on their milk productivity. At the same time, it is most effective to feed sapropel at the dose of 300 g/ head/day.

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