scholarly journals Is visceral obesity the cause of obesity paradox?

2017 ◽  
Vol 62 (6) ◽  
pp. 33-39 ◽  
Author(s):  
Daria A. Borodkina ◽  
Olga V. Gruzdeva ◽  
Ludmila V. Kvitkova ◽  
Olga L. Barbarash
Keyword(s):  
Visceral Obesity ◽  
Diabetes Type 2 ◽  
Obesity Paradox ◽  
Epidemiological Studies ◽  
Overweight And Obesity ◽  
The Body ◽  
Markers Of Inflammation ◽  
Obesity And Overweight ◽  
Long Term Prognosis

Obesity is one of the 10 risk factors of death. Many epidemiological studies have shown that overweight and obesity are associated with 44% cases of diabetes type 2, and 23% of cases of coronary heart disease. The body mass index (BMI) is traditionally a diagnostic marker of obesity and overweight are considered. However, in the last 15 years, there has been work on the «paradox» of obesity. So the obese long-term prognosis and stroke are more favorable than individuals without excess weight and obesity. A deeper analysis of the data showed that the highest risk of developing cardiovascular disease and disorders of carbohydrate metabolism associated with visceral obesity. This is largely due to metabolic disorders occurring on the background of visceral obesity, such as insulin resistance, hyperglycemia, dyslipidemia, an imbalance of adipokines and markers of inflammation. These changes in individuals with visceral obesity can occur regardless of the value of BMI.

scholarly journals Association between Obesity and Overweight and Cardiorespiratory and Muscle Performance in Adolescents

2020 ◽  
Vol 18 (1) ◽  
pp. 134
Author(s):  
Peter Petrovics ◽  
Barbara Sandor ◽  
Anita Palfi ◽  
Zsolt Szekeres ◽  
Tamas Atlasz ◽  
...  
Keyword(s):  
Seasonal Fluctuation ◽  
Overweight And Obesity ◽  
The Body ◽  
Muscle Performance ◽  
Aerobic Performance ◽  
Childhood And Adolescence ◽  
Inverse Association ◽  
Obesity And Overweight ◽  
Short And Long Term

The high prevalence of obesity in childhood and adolescence has major public health consequences, since it is associated with various chronic diseases in the short- and long-term. The goal of our study was to examine the possible association between obesity and overweight and cardiorespiratory and muscle performance during a 4-year follow up period in adolescents. The body mass index (BMI) and physical performance of adolescents (360 girls and 348 boys) between 14–18 years of age was measured twice a year, and the possible correlation between overweight and obesity and cardiorespiratory and muscle performances were investigated. Our results revealed that cardiorespiratory performance increased significantly in boys during the 4 years (p < 0.001), but the aerobic performance of girls only showed seasonal fluctuation. Muscle performance significantly increased both in boys and girls (p < 0.001). Inverse association between obesity and cardiorespiratory and muscle performance was proved. Overweight was also inversely correlated with cardiorespiratory performance, but it demonstrated no correlation with muscle strength. Avoiding increased BMI and decreased physical fitness is essential for adolescents’ health to prevent short- and long-term adverse effects.

scholarly journals “Childhood Obesity its Factors, Complications and Impact on Overall Health in Children”

2021 ◽  
pp. 1-5
Author(s):  
Asma Saghir Khan
Keyword(s):  
Physical Activity ◽  
Childhood Obesity ◽  
Health Care Professionals ◽  
Genetic Factors ◽  
Overweight And Obesity ◽  
Family Influences ◽  
Childhood Overweight And Obesity ◽  
Number Of Factors ◽  
Obesity And Overweight

Childhood, overweight and obesity are increasingly significant problems, and ones that are likely to endure and to have long term adverse influences on the health of individuals and populations unless action is taken to reverse the trend. A number of factors have been suggested as contributing to the development of childhood obesity. These include genetic factors, decreasing levels of physical activity, increased time spent in sedentary behavior and changes in diet. In addition, lifestyle factors, including family influences, changes in society and media advertising, have been associated with the increasing incidence of obesity and overweight in childhood. To address the problem, health care professionals should incorporate appropriate screening in their child practice. Comprehensive assessment of children who are, or who are at risk of becoming, obese is also necessary

scholarly journals Overweight And Obesity Repercussion In The Postoperative Of Myocardial Revascularization Surgery

2014 ◽  
Vol 48 (2) ◽  
pp. 236-241 ◽  
Author(s):  
Nyagra Ribeiro de Araújo ◽  
Raul Amaral de Araújo ◽  
Simone Maria Muniz da Silva Bezerra
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Myocardial Revascularization ◽  
Cardiovascular Complications ◽  
Overweight And Obesity ◽  
The Body ◽  
Cross Sectional ◽  
Obesity And Overweight ◽  
Obese Subjects ◽  
Revascularization Surgery

This is a descriptive, retrospective study with cross-sectional quantitative approach, which aimed to relate the body mass index with events in the postoperative period of the myocardial revascularization surgery with use of extracorporeal circulation. The data collection period was between April and June/2012. Patients were divided according to the body mass index and classified as without excess of weight, overweight or obese. The data analysis was based on the descriptive statistics. The patients without excess of weight had more complications, especially those related to the lungs. Among overweight and obese individuals, the cardiovascular complications stood out. The obese subjects had the worse prognostic. Obesity and overweight did not have statistically significant association with a higher frequency of postoperative complications, in spite of the occurrence of cardiovascular complications in this group. The patients without excess of weight had higher risks of developing neurological events.


scholarly journals Estimation of metformin and other sugar reducing therapy influence on the outcomes in patients with acute coronary syndrome and diabetes mellitus type II

2021 ◽  
Vol 10 (4) ◽  
pp. 39-47
Author(s):  
K. Yu. Nikolaev ◽  
K. I. Bondareva ◽  
A. Ya. Kovaleva ◽  
G. I. Lifshits
Keyword(s):  
Myocardial Infarction ◽  
Acute Coronary Syndrome ◽  
Cardiovascular Events ◽  
Diabetes Type 2 ◽  
Diabetes Type ◽  
Coronary Syndrome ◽  
Estimated Risk ◽  
Long Term Prognosis

Aim. To study the influence of hypoglycemic therapy on hospital and long-term prognosis in patients with acute coronary syndrome (ACS) and diabetes type 2.Methods. The study included 63 patients with ACS and type 2 diabetes. All patients had a clinical examination, assessment of mortality risk and myocardial infarction on GRACE scale (Global Registry of Acute Coronary Events) and TIMI (Thrombolisis In Myocardial Infarction) in-hospital and six months after hospitalization.Results. Metformin is associated with a lower estimated risk of in-hospital mortality and within 6 months after discharge in patients with acute coronary syndrome on the background of type 2 diabetes and with less risk of adverse cardiovascular events within 14 days of their occurrence in patients with unstable angina pectoris on the background of diabetes. High daily doses of metformin have also been associated with a decrease in the estimated risk of in-hospital mortality and within 6 months after discharge in patients with ACS associated with diabetes. The inverse association between the daily dosage of metformin and the presence of angina pectoris in patients with ACS and diabetes type 2 indicates a protective effect of metformin high daily dosages in relation to the risk of complications within six months after the discharge from hospital.Conclusion. One of the important aspects of ACS treatment, along with effective therapy, is the impact on concomitant risk factors, including blood glucose control. The main groups of hypoglycemic drugs have currently been identified; their effect on cardiovascular events, long-term effects and long-term prognosis are being investigated.

scholarly journals The prevalence of obesity and overweight in Northeastern Iran

2018 ◽  
Vol 4 (1) ◽  
pp. 1-10 ◽  
Author(s):  
Hakimeh Saadatifar ◽  
Hadi Ostadimoghaddam ◽  
Fahimeh Khoshhal ◽  
Frida Jabbari-Azad ◽  
Saman Mohazzab-Torabi ◽  
...  
Keyword(s):  
Cross Sectional Study ◽  
Overweight And Obesity ◽  
The Body ◽  
Health Policies ◽  
Sectional Study ◽  
Cross Sectional ◽  
Who Criteria ◽  
Obesity And Overweight ◽  
Prevalence Of Obesity ◽  
The Mean

Objective: The aim of this study was to assess obesity and overweight by WHO criteria in Mashhad, Iran. Method: This cross-sectional study was performed on 4453 people from Mashhad in 2009. Comprehensive data of age, height, weight, education, and marriage was collected. Overweight and obesity were calculated according to the body mass index (BMI). Results: A total of 1828 participants entered study, of whom 70.4% were women. The mean age of the population was 39.8±13.5 years. The prevalence of overweight and obesity was 36.5% (95% CI 34.3-38.6) and 16.9% (95% CI 15.1-18.8), respectively. The prevalence of overweight was 39.0% in men and 35.4% in women which increased significantly by age (P<0.001 & OR=1.055). The prevalence of obesity in men and women was 12.3% and 18.9% respectively which showed women had a significantly higher risk (P<0.001). The risk of overweight and obesity was higher in married but lower in educated people. Conclusion: This study showed a rapid increase in obesity and overweight, especially in women, in Mashhad population as a sample of the Iranian society. Attention to preventive and education plans should be the priority of health policies.

scholarly journals Euvolemia as a criterion of diuretic therapy efficacy in chronic heart failure: Literature review

2020 ◽  
Vol 35 (2) ◽  
pp. 13-25
Author(s):  
A. A. Garganeeva ◽  
E. A. Kuzheleva ◽  
V. Yu. Mareev
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Diuretic Therapy ◽  
Optimal Dose ◽  
Developed Countries ◽  
The Body ◽  
Hydration Status ◽  
Long Term Prognosis ◽  
Volume Retention

Chronic heart failure (CHF) is a typical outcome for all pathological processes affecting the cardiovascular system and is diagnosed in 1–2% of the population in developed countries. The strategy for managing patients with CHF involves the prescription of diuretics for the relief of volume retention syndrome in addition to pathogenetic pharmacotherapy. Considering the confl icting data concerning the effects of diuretics on the long-term prognosis and clinical course of CHF, a strict approach to the analysis of risk/benefit ratio is necessary while choosing a specific diuretic and determining its optimal dose and duration of use. The article reviews state-of-theart literature on the assessment of hydration status in patients with CHF. The euvolemia state, in which the optimal volume of fl uid is achieved in the body of a patient with CHF is viewed from the perspective of evaluating the efficacy and relevance of diuretic therapy.

scholarly journals Key factors of inflammation and long-term prognosis in patients with myocardial infarction and visceral obesity

2020 ◽  
pp. 77-82
Author(s):  
E. G. Uchasova ◽  
E. V. Belik ◽  
O. V. Gruzdeva ◽  
Y. A. Dileva ◽  
A. A. Kuzmina
Keyword(s):  
Myocardial Infarction ◽  
Vascular Complications ◽  
Visceral Obesity ◽  
Control Group ◽  
Key Factors ◽  
Reactive Protein ◽  
Long Term Prognosis ◽  
Cardio Vascular ◽  
Factor Α

Objective: To assess the relation between key factors of inflammation and myocardial infarction complications in different stages of the diseases in patients with visceral obesity.Methods: Men with the diagnosed myocardial infarction were examined: 64 of them with visceral obesity (the first group) and 30 of them without visceral obesity (the second group). On the 1s t and 12th day of hospitalization, the serum concentrations of interleukins (IL) 1β, 6, 8, 10 and 12, tumor necrosis factor α (TNFα) and C-reactive protein (CRP) were determined. The control group included 30 healthy men.Results: The cytokine profile in visceral obesity was characterized by the increase in concentration of proinflammatory ILs and the decrease in concentration of IL-10. The concentration increase was: 1.3 times for IL-1 and TNFα, 2 times for IL-12, 6 times for IL-6 and 24 times for IL-8 and CRP. The increase in IL-6 and CPR levels in blood serum was associated with the obesity.Conclusions: The development of adverse cardio‑ vascular complications a year later after the previous myocardial infarction is typical for patients with visceral obesity and is followed by the activation of proinflammatory cytokines and deficiency of IL-10. 

scholarly journals Evaluation of the relationship between body composition and weight-height index – BMI

2019 ◽  
Vol 73 ◽  
pp. 572-580
Author(s):  
Katarzyna Banach ◽  
Paweł Glibowski ◽  
Paulina Skorek
Keyword(s):  
Body Composition ◽  
Body Mass ◽  
Body Fat ◽  
Epidemiological Studies ◽  
Overweight And Obesity ◽  
The Body ◽  
Impedance Method ◽  
Composition Analysis ◽  
Obese People ◽  
The Relationship

Aim: Body composition, especially the mass of adipose tissue, affects the risk of developing the metabolic and cardiovascular diseases as well as some cancers. The aim of this study was to determine the relationship between the body composition of adults and their Body Mass Index. Material/Methods: The study involved 120 subjects (69 women and 51 men) aged 19 – 66 (30.55 ± 10.41). The recruited subjects were assigned to three subgroups: with normal body weight, overweight and obesity, depending on the BMI value. There were 40 subjects in each subgroup, including 23 women and 17 men. Besides the measurements of height and body mass, the SECA mBCA515 analyser was applied for the body composition analysis using the bioelectric impedance method. Results: A significant association was found between the BMI index and fat mass, lean mass and muscle mass, both in the whole group and after taking into account the sex. The correlation coefficient R range was from –0.88 to 0.97. The incidence of obesity in the studied group according to body fat content criteria (>25% for men and >30% for women) was 57%, while according to BMI criteria –33%. BMI cut-off points for obesity were 27.8, 26.4 and 26.4 kg/m2 for men, women and for all, respectively. Conclusions: In epidemiological studies, to identify obese people, body fat should also be taken into account in addition to BMI. If obesity is understood as excess fat, and not excess weight, the cut-off points for BMI-based obesity should be lowered.

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