scholarly journals ANALISIS KANDUNGAN FITOKIMIA PADA BERBAGAI JENIS MAKROALGA DI PANTAI JUNGWOK, KABUPATEN GUNUNGKIDUL, YOGYAKARTA (Analysis of Phytochemical Contents in Various Types of Macroalgae at Jungwok Beach, Gunungkidul District, Yogyakarta)

2020 ◽  
Vol 16 (1) ◽  
pp. 15-21
Author(s):  
Heny Budi Setyorini ◽  
Ernastin Maria
Keyword(s):  
Bioactive Compounds ◽  
Qualitative Approach ◽  
Test Method ◽  
Fresh Sample ◽  
Screening Analysis ◽  
Purposive Sampling ◽  
Water Fraction ◽  
Qualitative Test ◽  
Phytochemical Contents

Penelitian ini bertujuan untuk mengetahui kandungan fitokimia pada berbagai jenis makroalga di Pantai Jungwok, Kabupaten Gunungkidul, Yogyakarta. Penelitian ini dilaksanakan di Pantai Jungwok, Kabupaten Gunungkidul, Yogyakarta. Materi penelitian ini adalah makroalga (Ulva sp., Gracillaria sp., dan Boergesenia sp). Metode yang digunakan dalam penelitian ini adalah survei dengan pendekatan kualitatif. Teknik pengambilan sampel makroalga menggunakan purposive sampling. Lokasi pengambilan sampel makroalga berada di bagian timur, tengah dan barat Pantai Jungwok. Analisis skrining fitokimia dilakukan dengan uji kualitatif. Analisis skrining alkaloid menggunakan metode Culvenor Fitzgerald, sedangkan untuk steroid dan terpenoid menggunakan metode Liebermann-Buchard Test, pada fraksi air yang terbentuk dilanjutkan dengan uji flavonoid, fenolik dan safonin. Hasil penelitian menunjukan bahwa sampel segar makroalga jenis Gracilaria sp., yang berada di bagian tengah Pantai Jungwok paling banyak mengandung senyawa bioaktif seperti alkaloid, terpenoid dan flavonoid. The objective of this research was to identify the content of phytochemical in various types of macroalgae at Jungwok Beach, Gunungkidul District, Yogyakarta. This research was conducted at Jungwok Beach, Gunungkidul District, Yogyakarta. The material of this research were macroalgae (Ulva sp., Gracillaria sp., and Boergesenia sp.). This method of research used survey with a qualitative approach. The technique of collecting data was done through purposive sampling. The macroalgae samples were collected from the eastern, central and western part of Jungwok Beach. The phytochemical tests were carried out using qualitative test. Alkaloid screening analysis using the Culvenor Fitzgerald method, while for steroids and terpenoids using the Liberman Buchard Test method, the formed water fraction is followed by flavonoid, phenolic and safonin tests. The results showed that fresh sample of the macroalgae type Gracilaria sp., which is located in the middle of Jungwok Beach, contains the most bioactive compounds such as alkaloids, terpenoids and flavonoids.

Penerapan Psikologi Islam dalam Praktek Profesi Psikolog Muslim

2020 ◽  
Vol 3 (1) ◽  
pp. 47-60
Author(s):  
Yulia Hairina ◽  
Mubarak Mubarak
Keyword(s):  
Discussion Group ◽  
Qualitative Approach ◽  
Psychological Services ◽  
Reference Source ◽  
Sampling Techniques ◽  
Purposive Sampling ◽  
Primary Reference ◽  
Islamic Psychology

This research aims to describe the application of Islamic Psychology in the practice of Muslim psychologists and the obstacles in its application. This study uses a qualitative approach for taking respondents using purposive sampling techniques. There are twenty respondents in this study. The method used in collecting data from this study is the interview and Focus Discussion Group. This study found that the understanding of Islamic Psychology was quite diverse, but in essence, an approach that used the Qur'an and Hadist was the primary reference source. Its application, including the psychological services, and the process of counseling and therapy were carried out by integrating psychology and Islam. The cases also handled varied, not limited to severe or mild cases. The challenges were related to the ability of the psychologists and the acceptance of the clients.

scholarly journals Comparison of the Phytochemical Properties, Antioxidant Activity and Cytotoxic Effect on HepG2 Cells in Mongolian and Taiwanese Rhubarb Species

Molecules ◽  
2021 ◽  
Vol 26 (5) ◽  
pp. 1217
Author(s):  
Ganbolor Jargalsaikhan ◽  
Jin-Yi Wu ◽  
Yen-Chou Chen ◽  
Ling-Ling Yang ◽  
Ming-Shun Wu
Keyword(s):  
Liver Cancer ◽  
Bioactive Compounds ◽  
Cytotoxic Effect ◽  
Antioxidant Properties ◽  
Radical Scavenging ◽  
Ethanol Extract ◽  
Parp Cleavage ◽  
Total Phenolic ◽  
Antioxidant Capacities ◽  
Phytochemical Contents

The Mongolian rhubarb—Rheum undulatum L. (RU)—and Rumex crispus L. (RC)—a Taiwanese local rhubarb belonging to the family of Polygonaceae—are principal therapeutic materials in integrative medicine due to their rich quantities of bioactive compounds; however, their phytochemical and antioxidant properties, and anti-cancer activity is poorly investigated. Furthermore, the phytochemical characteristics of both species may be affected by their different geographical distribution and climatic variance. The current study aimed to compare RU with RC extracts in different polarity solvents (n-hexane, ethyl acetate, acetone, ethanol, and water) for their phytochemical contents including the total phenolic content (TPC), total anthraquinone content (TAC), total flavonoid content (TFC), antioxidant and free radical scavenging capacities, and anticancer ability on the HepG2 cell. Except for the n-hexane extract, all of the RU extracts had considerably higher TPCs than RC extracts, ranging from 8.39 to 11.16 mg gallic acid equivalent (GAE) per gram of dry weight, and the TPCs of each extract were also significantly correlated with their antioxidant capacities by ABTS, DPPH, and FRAP assays (p < 0.05). Moreover, there was no remarkable association between the antioxidant capacities and either TACs or TFCs in both the RU and RC extracts. Besides, high-performance liquid chromatography (HPLC) analysis revealed that both the RU and RC extracts contained chrysophanol, emodin, and physcion, and those bioactive compounds were relatively higher in the n-hexane solvent extracts. Additionally, we observed different levels of dose-dependent cytotoxic effects in all the extracts by cell viability assay. Notably, the ethanol extract of RU had a compelling cytotoxic effect with the lowest half-maximum inhibition concentration (IC50-171.94 ± 6.56 µg/mL at 48 h) among the RU extracts than the ethanol extract of RC. Interestingly, the ethanol extract of RU but not RC significantly induced apoptosis in the human liver cancer cell line, HepG2, with a distinct pattern in caspase-3 activation, resulting in increased PARP cleavage and DNA damage. In summary, Mongolian Rhubarb, RU, showed more phytochemical contents, as well as a higher antioxidant capacity and apoptotic effect to HepG2 than RC; thus, it can be exploited for the proper source of natural antioxidants and liver cancer treatment in further investigation.

Strategi Peserta Program Keluarga Harapan (PKH) Mempertahankan Status Pesertanya; Studi Nagari Punggasan Timur Kecamatan Linggo Sari Baganti Kabupaten Pesisir Selatan

2019 ◽  
Vol 3 (2) ◽  
pp. 10-25
Author(s):  
Casiavera
Keyword(s):  
Data Collection ◽  
Sampling Technique ◽  
Structuration Theory ◽  
Structured Interview ◽  
Qualitative Approach ◽  
Duality Relation ◽  
Purposive Sampling ◽  
Depth Interview ◽  
Anthony Giddens

This study explains about PKH recipients’ strategy to accept the assistance and not to be graduated. This study used the qualitative approach using descriptive type. Informants are chosen based on purposive sampling technique while data collection applies observation technique and in-depth interview (loosely structured interview). It uses Structuration theory proposed by Anthony Giddens which focuses on duality relation between agent and structure.

scholarly journals MATA KULIAH PENDIDIKAN KEWARGANEGARAAN SEBAGAI UPAYA MEMUPUK RASA NASIONALISME MAHASISWA (Studi Kasus Pada Mahasiswa Universitas Buana Perjuangan Karawang)

2018 ◽  
Vol 2 (1) ◽  
Author(s):  
Yogi Nugraha
Keyword(s):  
Civic Education ◽  
Teacher Candidates ◽  
Case Study Research ◽  
Target Population ◽  
Study Time ◽  
Qualitative Approach ◽  
Purposive Sampling ◽  
Study Research ◽  
Education Courses

ABSTRACT This study aims to describe the implementation of civic education courses in an effort to foster a sense of nationalism student at the Buana Perjuangan Karawang University. This study used a qualitative approach with the method used is the case study. Research conducted at the Buana Perjuangan Karawang University, with an estimated study time for start of the date October 28, 2017 until August 28, 2018. The target population in this study were students who follow courses of civic education, and sampling using techniques purposive sampling. The results obtained show that nationalism formed through civic education in college can be formed. It is based on a statement cited by respondents stated that the Civic Education is very important to learn in college, it's based on the erosion of a sense of nationalism began to be immediately addressed by studying Civics. Civic education is also learned to go back to the students will be taught by the teacher candidates Pancasila and Civic Education. Increased sense of nationalism in studying Civics is proof that Civic Education is so important to learn. Keywords: Civic Education, Nationalism, Students. ABSTRAK Penelitian ini bertujuan untuk mendeskripsikan pelaksanaan mata kuliah pendidikan kewarganegaraan dalam upaya memupuk rasa nasionalisme mahasiswa di Universitas Buana Perjuangan Karawang. Penelitian ini menggunakan pendekatan kualitatif dengan metode yang digunakan yaitu metode studi kasus. Penelitian dilaksanakan pada Universitas Buana Perjuangan Karawang, dengan estimasi waktu penelitian selama mulai dari tanggal 28 Oktober 2017 sampai dengan tanggal 28 Agustus 2018. Populasi target dalam penelitian ini adalah mahasiswa yang mengikuti mata kuliah pendidikan kewarganegaraan, dan pengambilan sampel menggunakan teknik purposive sampling. Hasil penelitian yang diperoleh menunjukkan bahwa nasionalisme yang terbentuk melalui pembelajaran pendidikan kewarganegaraan di perguruan tinggi dapat terbentuk. Hal ini berdasarkan pernyataan yang diutarakan oleh para responden yang menyatakan bahwa Pendidikan Kewarganegaraan sangat penting untuk dipelajari di Perguruan Tinggi, hal ini didasarkan pada mulai lunturnya rasa nasionalisme haruslah segera diatasi dengan mempelajari Pendidikan Kewarganegaraan. Pendidikan Kewarganegaraan juga dipelajari untuk kembali dibelajarkan kepada peserta didik nantinya oleh para calon guru Pendidikan Pacasila dan Kewarganegaraan. Meningkatnya rasa nasionalisme dalam mempelajari Pendidikan Kewarganegaraan merupakan bukti bahwasanya Pendidikan Kewarganegaraan begitu penting untuk dipelajari. Kata kunci: Pendidikan Kewarganegaraan, Nasionalisme, Mahasiswa.

scholarly journals MENGUNGKAP PERSEPSI WAJIB PAJAK ATAS PENDAMPINGAN RELAWAN PAJAK

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
I Nyoman Putra Yasa ◽  
Ni Made Ayu Sri Putri Artini ◽  
Luh Melly Astari ◽  
Ni Putu Purnama Sari
Keyword(s):  
Sampling Technique ◽  
Research Data ◽  
Qualitative Approach ◽  
Research Use ◽  
Purposive Sampling ◽  
Volunteer Program ◽  
Interview Techniques ◽  
Technological Advances ◽  
Reporting Process ◽  
Tax Returns

<div class="WordSection1"><p><strong><em>ABSTRACT:</em></strong><em> The purpose of this research to explore the perceptions of taxpayers on the satisfaction of assistance performed by tax volunteers at the Tax Volunteer placement location. There are 4 (four) locations for the placement of Tax Volunteers, namely KPP Pratama Singaraja, KP2KP Negara, KP2KP Amlapura and Tax Center Undiksha. This research use desciptive qualitative approach. The sampling technique used in this research was purposive sampling with interview techniques in collecting research data. The population in this research are taxpayers who carry out the duty to annual tax return through e-Filing. Meanwhile, the sample in this research were taxpayers whose reporting the annual tax return were assisted by Tax Volunteers in the 4 (four) placements. The results of this research indicate that taxpayer assistance activities by tax volunteers in helping to fill individual annual tax returns are very effective. This can be seen from the satisfaction of taxpayers after receiving assistance by Tax Volunteers. Taxpayers are satisfied with the assistance of tax volunteers because the annual tax return reporting process is easier, faster and Tax Volunteers are able to guide Taxpayers in filling out their own. This assistance helps reduce the difficulties experienced by Taxpayers in understanding SPT filling independently. Taxpayer satisfaction is expected to increase compliance in reporting the Annual Tax Return. The sustainability of the Tax Volunteer program is also highly expected because it is considered very effective for taxpayers who do not understand the procedures for submitting annual tax return, especially those who are not yet competent with technological advances.</em></p><p><strong><em>Keywords</em></strong><em>: Perception, Assistance, e-Filing, Tax Volunteers</em></p><p> </p><p><strong>ABSTRAK:</strong> Penelitian ini bertujuan untuk menggali persepsi wajib pajak atas kepuasan pendampingan yang dilakukan oleh Relawan Pajak di lokasi penempatan relawan pajak. Adapun 4 (empat) lokasi penempatan Relawan Pajak yaitu KPP Pratama Singaraja, KP2KP Negara, KP2KP Amlapura dan <em>Tax Center</em> Undiksha. Penelitian ini menggunakan pendekatan deskriptif kualitatif. Teknik penentuan sampel yang digunakan dalam penelitian ini adalah <em>purposive sampling</em> dengan teknik wawancara dalam pengumpulan data penelitian. Yang menjadi populasi dalam penelitian ini adalah Wajib Pajak yang melaksanakan kewajiban dalam melaporkan SPT Tahunan melalui <em>E-Filing</em>. Sedangkan, sampel dalam penelitian ini yakni Wajib Pajak yang kegiatan pelaporan SPT Tahunannya didampingi oleh Relawan Pajak di 4 (empat) penempatan tersebut. Hasil penelitian ini menunjukan bahwa kegiatan pendampingan wajib pajak oleh relawan pajak dalam membantu pengisian SPT tahunan orang pribadi sangat efektif. Hal ini dapat dilihat dari kepuasan wajib pajak setelah mendapatkan pendampingan oleh relawan pajak. Wajib Pajak puas atas pendampingan relawan pajak dikarenakan proses pelaporan SPT Tahunan menjadi lebih mudah, cepat dan para relawan pajak mampu menuntun wajib pajak dalam pengisian SPT-nya. Pendampingan ini membantu mengurangi kesulitan yang dialami Wajib Pajak dalam memahami pengisian SPT secara mandiri. Kepuasan Wajib Pajak diharapkan mampu meningkatkan kepatuhan dalam pelaporan SPT Tahunan. Keberlanjutan program relawan pajak juga sangat diharapkan karena dinilai sangat efektif bagi wajib pajak yang belum mengerti tata cara penyampaian SPT khususnya yang belum cakap akan kemajuan teknologi.</p><p><strong>Kata kunci</strong>: Persepsi, Pendampingan, <em>E-Filing</em>, Relawan Pajak</p><p><em> </em></p></div><strong><br clear="all" /> </strong>

scholarly journals Postnatal Depression in Malaysia: Perspectives of Stakeholder on Awareness Medium

2021 ◽  
Vol 20 (2) ◽  
Author(s):  
Aishah Siddiqah Alimuddin ◽  
Tuti Iryani Mohd Daud ◽  
Umi Adzlin Silim ◽  
Mohd Abdul Wahab Fatoni Mohd Balwi ◽  
Ani Amelia Zainuddin ◽  
...  
Keyword(s):  
Postnatal Depression ◽  
Cultural Context ◽  
Help Seeking ◽  
Qualitative Approach ◽  
University Hospital ◽  
Educational Video ◽  
Educational Tool ◽  
Purposive Sampling ◽  
Face To Face ◽  
Local Setting

INTRODUCTION: Postnatal depression is a highly prevailing illness, yet underdiagnosed. Untreated, it carries a transgenerational impact, and therefore promoting awareness for it has to be of high priority. This research explored the elements of an educational tool to develop awareness for postnatal depression as preferred by stakeholders. MATERIALS AND METHOD: A descriptive qualitative approach using semi-structured face-to-face interviews were conducted, where nine participants were recruited via purposive sampling from a university hospital in Malaysia. Interviews with each participant were audio-recorded and transcribed to verbatims. Emergent themes were identified during the analysis. RESULTS: Four consistent themes regarding elements for an educational tool were derived as follows: Foundations of the tool, Illness circumstances, Support bases, and Matters of perspective. CONCLUSION: An educational video within the local setting should involve the usage of a short emotionally driven video, highlighting illness- and treatment-related content, and addressing the preference and concerns of women within the religious and cultural context. The use of edutainment as an educational tool is replicable and has a high outreach even to those who are illiterate. The findings can be used in the tailored development of an educational video on postnatal depression which will benefit local women by creating awareness and encouraging early help-seeking.

scholarly journals Lignolytic Enzyme Activity of Isolated Bacteria from Termite (Coptotermes Sp.) and Milkfish (Chanos chanos Forsskal, 1775) Guts

2021 ◽  
Vol 13 (1) ◽  
pp. 70-76
Author(s):  
Emi Latifah ◽  
Putri Dwi Mulyani ◽  
Yekti Asih Purwestri
Keyword(s):  
Enzyme Activity ◽  
Bacillus Licheniformis ◽  
Test Method ◽  
Chanos Chanos ◽  
Enzyme Isolation ◽  
Optimum Ph ◽  
Qualitative Test ◽  
Pseudomonas Alcaligenes ◽  
Enzyme Source ◽  
Brevibacillus Parabrevis

Bacteria BSR 2, Pseudomonas alcaligenes (BSR 3), Brevibacillus parabrevis (BSR 8), Brevibacillus sp. (BSR 9), isolated from termite gut and Bacillus licheniformis (BSA B1) isolated from milkfish gut have been known to possess celluloytic activity. However, their lignolytic ability has not been known. This study aimed to determine the lignolytic ability of bacteria isolated from termit (Coptotermes sp.) and milkfish (Chanos chanos Forsskal, 1775) guts and their enzymes characterization. The qualitative test was done through the spot test method, while quantitative assay was performed spectrophotometrically at 335 nm to calculate vanillin concentration. The isolates were grown in Lignin Mineral Medium, then the optical density (OD620) were measured every 24 hours for 5 days using spectrophotometer to determine their growth profile and the best isolation time of the lignolytic enzyme. Based on results, the best lignolytic enzyme isolation time for strains Bacillus licheniformis (BSA B1) and BSR 2 were 5 days, yielding lignolytic enzyme activity of 0.961 ± 0.168 U/mg and 2.176 ± 0.088 U/mg respectively,  while strains Pseudomonas alcaligenes (BSR 3), Brevibacillus parabrevis (BSR 8), and Brevibacillus sp. (BSR 9) were 4 days, yielding of 1.206 ± 0.045 U/mg, 1.162 ± 0.191 U/mg, and 0.896 ± 0.108 U/mg, respectively. The strain BSR 2 showed the highest lignolytic activity compared to other strains. The optimum temperature for lignolytic enzyme activity of BSR 2 was 30 ℃ and the optimum pH was 7. The lignolytic enzyme activity showed that these bacterial isolates can be a chance to be used as new alternative lignolytic enzyme source in commercial bioconversion process.

scholarly journals PENGARUH PROFITABILITAS TERHADAP NILAI PERUSAHAAN DENGAN PENGUNGKAPAN CORPORATE SOCIAL RESPONSIBILITY (CSR) SEBAGAI VARIABEL PEMODERASI Studi Empiris Pada Perusahaan Pertambangan yang Terdaftar di Jakarta Islamic Index Periode 2010 - 2017

2018 ◽  
Vol 7 (2) ◽  
Author(s):  
Wahyuni Wahyuni ◽  
I Nyoman Nugraha A P ◽  
Siti Aisyah Hidayati
Keyword(s):  
Corporate Social Responsibility ◽  
Social Responsibility ◽  
Firm Value ◽  
Positive Influence ◽  
Test Method ◽  
Purposive Sampling ◽  
Company Value ◽  
Analysis Technique ◽  
Csr Disclosure ◽  
Corporate Social

This study aims to analyze how the influence of profitability on company value and how the influence of profitability on company value with CSR disclosure as a moderating variable. With the purposive sampling method, there are four samples of mining sector companies listed in the Jakarta Islamic Index for the period 2010-2017. Data is processed using SPSS version 23. The analysis technique in this study uses simple linear regression and Moderated Regression Analysis (MRA). MRA is used in this study to analyze CSR Disclosure as a variable that moderates the effect of the independent variable Profitability on the dependent variable Company Value.The result of the research which has been done by using multiple linear regressions shows that profitability has significant and positive influence to the firm value. Meanwhile, the analysis of moderating variable with the interaction test method of MRA shows that the disclosure of corporate social responsibility does not moderate the influence of profitability on the firm value.Penelitian ini bertujuan untuk menganalisis bagaimana pengaruh profitabilitas terhadap nilai perusahaan dan bagaimana pengaruh profitabilitas terhadap nilai perusahaan dengan pengungkapan CSR sebagai variabel pemoderasi. Dengan metode purposive sampling, didapatkan empat sampel perusahaan sektor pertambangan yang terdaftar di Jakarta Islamic Index periode 2010 – 2017.  Data diolah menggunakan SPSS versi 23. Teknik analisis dalam penelitian ini menggunakan regresi linier dan Moderated Regresion Analisys (MRA). MRA digunakan di dalam penelitian ini untuk menganalisis Pengungkapan CSR sebagai variabel yang memoderasi pengaruh antara variabel independen Profitabilitas pada variabel dependen Nilai Perusahaan. Hasil penelitian dengan regresi linear berganda menunjukkan bahwa profitabilitas berpengaruh positif dan signifikan terhadap nilai perusahaan. Sedangkan analisis variabel moderating dengan metode uji interaksi MRA menunjukkan bahwa pengungkapan corporate social responsibility tidak memoderasi pengaruh profitabilitas pada nilai perusahaanKeywords:Profitabilitas, ROA, Nilai Perusahaan, Tobin’s Q, Pengungkapan CSR

scholarly journals Skrining Mekanisme Kerja Daun Malaka (Phyllanthus emblica L.) Sebagai Antidiabetes

2018 ◽  
Vol 1 (3) ◽  
pp. 106-110
Author(s):  
Novi Irwan Fauzi ◽  
Seno Aulia Ardiansyah ◽  
Saeful Hidayat
Keyword(s):  
Mechanism Of Action ◽  
Inhibitory Activity ◽  
Leaf Extract ◽  
Test Method ◽  
Diabetic Rat ◽  
Phyllanthus Emblica ◽  
Insulin Sensitizer ◽  
Water Fraction

Daun malaka (Phyllanthus emblica L.) mempunyai potensi digunakan sebagai alternatif obat antidiabetes. Daun malaka menunjukkan efek hipoglikemia pada tikus yang diinduksi aloksan. Namun, mekanisme kerjanya belum diketahui pasti. Penelitian ini dilakukan dalam rangka skrining mekanisme kerja daun malaka sebagai antidiabetes. Skrining mekanisme kerja dilakukan terhadap fraksi air daun malaka melalui uji aktivitas inhibisi enzim α-glukosidase serta α-amilase secara in vitro dan pengujian aktivitas insulin-sensitizer terhadap ekstrak daun malaka dengan metode tes toleransi insulin secara in vivo. Fraksi air daun malaka menunjukkan aktivitas inhibisi terhadap enzim α-glukosidase serta α-amilase dengan nilai IC50 (Inhibitor Concentration 50) pada kedua enzim tersebut berturut-turut adalah 0,87% dan 8,64% b/v. Pada uji aktivitas insulin sensitizer, pemberian ekstrak daun malaka dapat meningkatkan sensitivitas insulin pada tikus diabet dengan kondisi resistensi insulin. Nilai KTTI pada kelompok tikus diabet yang diberi ekstrak daun malaka dosis 100 dan 500 mg/kgbb tikus (74,89 dan 75,57) lebih tinggi dibandingkan kelompok tikus diabet (38,41) dan kadar glukosa darah yang lebih rendah selama interval waktu pengukuran. Daun malaka telah diketahui mampu meningkatkan sekresi insulin dan pada penelitian ini menunjukkan aktivitas inhibisi enzim α-glukosidase serta α-amilase secara in vitro dan menunjukkan aktivitas insulinsensitizer pada tikus diabet dengan kondisi resistensi insulin.   Malaka leaf (Phyllanthus emblica L.) has the potential to be used as an alternative antidiabetic drug. Malacca leaves showed hypoglycemia effect in rat induced by alloxan. However, the mechanism of action is not yet known. This study was conducted to evaluate the mechanism of action of Malaka leaves as antidiabetic. Screening of the mechanism of action was carried out on the water fraction of Malaka leaf  byinhibitory activity examination  on α-glucosidase and α-amylase by in vitro studyand Evaluation of insulin-sensitizer activity of Maaka leaf leaf extract was conducted by invivo  insulin tolerance test method. Malaka leaf water fraction showed inhibitory activity against the α-glucosidase and α-amylase with IC50 values ​​(Inhibitory Concentration 50)  of0.87% and 8.64% b / v on both enzyme, respectively. The evaluation of insulin sensitizer revelead that administration ofMalaka  leaf extract can increase insulin sensitivity in diabetic rat with insulin resistance.KTTI values ​​in diabetic rats given malaka extract  at the dose of 100 and 500 mg / kg BW (74.89 and 75.57) were higher than diabetics rat (38.41) and the extract also decrease blood glucose levels during measurement time intervals . Malaka leafhas been known to increase insulin secretion and the study showedthe  inhibitory activity on α-glucosidase and α-amylase by in vitro study and showed insulinsensitizer activity in diabetic rat with insulin resistance.

scholarly journals Enrichment of Apple Slices with Bioactive Compounds from Pomegranate Cryoconcentrated Juice as an Osmodehydration Agent

2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
M. E. Guerra-Valle ◽  
J. Moreno ◽  
S. Lillo-Pérez ◽  
G. Petzold ◽  
R. Simpson ◽  
...  
Keyword(s):  
Electric Field ◽  
Bioactive Compounds ◽  
Ohmic Heating ◽  
Soluble Solids ◽  
Pomegranate Juice ◽  
Total Flavonoids ◽  
Fresh Sample ◽  
Total Anthocyanin ◽  
Apple Slices ◽  
Combined Technique

Pomegranate juice is an important source of bioactive compounds, and cryoconcentrated juice is an interesting osmodehydration agent to enrich a vegetal matrix. This investigation aimed to incorporate bioactive compounds from pomegranate cryoconcentrated juice into apple slices using osmodehydration (OD) assisted by pulse vacuum (PV) and ohmic heating (OH). The apple slices (3 × 4 × 0.5 cm) were osmodehydrated using a 47 °Brix pomegranate cryoconcentrated juice at 30, 40, or 50°C for 180 min with an electric field of 6.66 V/cm (50 V) and a 5 min pulsed vacuum. Over the time, all of the treatments applied to the apple slices increased the soluble solids and bioactive compounds compared with the fresh sample. PVOD/OH at 50°C had the highest content of total anthocyanin during processing, and the best results for the total flavonoids were obtained with OD/OH at 50°C and 40°C. The osmodehydration assisted by pulse vacuum and ohmic heating using a cryoconcentrated juice is a useful combined technique to acquire enriched vegetal samples with bioactive compounds.

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