scholarly journals The effect of anti-microbial peptide on the performance, survival rate, and diarrhea ratio the pig: A meta-analysis

2021 ◽  
Vol 46 (3) ◽  
pp. 270-281
Author(s):  
D. N. Adli ◽  
O. Sjofjan ◽  
M. M. Sholikin ◽  
N. Qamariyah ◽  
T. R. Priambodo ◽  
...  

A meta-analysis conducted to determine effect of anti-microbial peptide (AMP) form on the per-formance of pig. A database was designed based on data published that reported used probiotic on pig. The method used in the selection of articles was based on the systematic review center for laboratory animal experimentation (SYRCLE's) method. The final database consisted of 41 in vivo studies with 241 treatments. The analysis statement in the system were R Version 3.6.30. In general, in the total phase, body weight and survival rate increased (p <0.05; quadratic) due to AMP administration. In continued of the phase 1, growth performance parameters [eg, body weight, average daily gain (ADG), and average daily intake (ADI), feed conversion ratio (FCR)] increased (p <0.05; quadratic) and FCR decreased (p <0.05; quadratic) due to SAP administration. In the total phase, parameters such as body weight, ADG, and survival rate increased (p <0.05; quadratic) while ADI tended to increase (p <0.1; linear) due to the increase in the CAP dose. Meanwhile, other parameters in the total phase, i.e. FCR decreased (p <0.05; quadratic). The optimal dose of CAP for the total phase was 21.406 mg/kg of feed with a predicted minimum FCR of 1.47. The AMP forms (SAP and CAP) improved (p <0.05) the pa-rameters of body weight, ADG, ADI, FCR, diarrhea ratios, and survival rate at each phase. In sum-mary, both form and dosage of the anti-microbial help to beneficial effect on the growth performance of pigs.

2021 ◽  
Vol 16 (1) ◽  
pp. 31-38
Author(s):  
Chunbo Wei ◽  
Xiuwei Lin ◽  
Ying Zhang ◽  
Xuanchen Wan ◽  
Haotong Wu ◽  
...  

Abstract This study aims to investigate the effects of different selenium (Se) sources on the growth performance of Chinese broilers and provide a scientific rationale for adding Se additives to broiler feed. Relevant studies that meet standard inclusion criteria were identified and extracted from China National Knowledge Infrastructure and Wanfang and Chinese Scientific Journal (VIP) databases. A total of 9 studies with 539 subjects were included. A meta-analysis was performed with STATA15.0 to estimate the combined standardized mean difference (SMD) with a 95% confidence interval (95% CI). Heterogeneity test of articles was examined by Q-test, and the results showed that P values of feed conversion ratio, average daily gain (ADG), and average daily intake were all less than 0.05, suggesting a strong heterogeneity among the selected literature. Therefore, the random effect model is selected to calculate the SMD of the three indexes. The combined SMDs (95% CI) of feed:gain, ADG, and average daily feed intake (ADFI) were −0.39 (−1.03, 0.25), 0.26 (−0.29, 0.81), and −1.45 (−3.09, 0.20), respectively, and the P values were all less than 0.05. This study shows that the absolute differences in the growth performance (feed:gain, ADG, and ADFI) of broilers fed with either organic or inorganic Se supplements at the same dose were quite small. The P values of Egger’s test were 0.770, 0.089, and 0.426, respectively, for the above indexes, showing no significant publication bias. Sensitivity analysis ensured the stability and reliability of the results. In summary, the effects of organic and inorganic Se in feed on the growth performance of broilers are statistically equal.


Author(s):  
Amr M.A. Elmasry ◽  
Luis A. Miranda ◽  
Germán Mendoza ◽  
Fernando X. Plata

Background: The effects of the probiotics vary with the doses and strains used for this reason, a study was conducted over 35 days to determine the effect of live yeast supplementation in the diet of growing rabbits on growth performance and apparent nutrient digestibility.Methods: A total of 60 New Zealand and California rabbits (5 weeks old, average body weight 0.881±0.015 kg) were housed in 30 cages. They were fed with a control diet based on alfalfa and maize or barley grains and supplemented with Procreatin®7 (Saccharomyces cerevisiae CNCM I 1077) or Biosaf® SC47 (Saccharomyces cerevisiae NCYC Sc47) at three doses, namely 0, 6.4, or 12.8 ×109 CFU per kg basal diet.Result: The higher yeast concentration had a positive effect (P less than 0.01) on final body weight (BW), average daily gain (ADG) and carcass weight (CW). However, there were no significant differences in dry matter intake. As a result of this, the feed conversion ratio (FCR) decreased (P less than 0.01). Significant increases (P less than 0.05) in nutrient digestibility (DM, OM, NDF and ADF) were observed with both grains. The use of yeast in maize and barley-based diets of rabbits has positive effects on growth performance and nutrient digestibility.


2021 ◽  
Author(s):  
shewangizaw woltamo wolde ◽  
Tadele Mirkena ◽  
Aberra Melesse ◽  
Tadelle Dessie ◽  
Solomon Abegaz

Abstract The Normal Feathered local chicken (LL), Sasso-RIR (SRSR) and their F1-cross (LSR) chickens were hatched to evaluated for egg hatchability, growth performance, feed efficiency and survival rate. After 14-days of brooding, 150 chicks of each genotype were randomly selected and further replicated in to five pens in a deep litter grower house consisting of 30 chicks each in a completely randomized design, and evaluated for a period of 16-weeks. Hatchability of fertile eggs was highest for LL (80.0 %), intermediate for LSR (68.6%) and lowest for SRSR (55.9%) chickens. The body weight (BW) of chicks at 2-weeks of age was 80.0, 76.3 and 61.5 g/bird for SRSR, LSR, and LL, respectively, the latter being the lowest (p<0.05). The respective BW at 8-weeks of age was 732, 587 and 451 g while at 18-weeks it was 1877, 1379 and 1070 g/bird and different from each other (p<0.05). During 3- to 8-weeks and 9- to 18-weeks growth periods, the LL chickens were inferior (p< 0.05) in feed intake (29.7 and 66.9 g/d/bird) whereas the SRSR chickens were superior (p< 0.05) in body weight gain (15.5 and 16.3 g/d/bird) and feed conversion ratio (2.67 and 5.35 g feed/ g gain), respectively. The mortality rate of chicken was not affected by genotypes. It can be concluded that the exotic blood of Sasso-RIR chicken had played a significant role in upgrading the growth rate and market weight of the local Normal Feathered chicken without adverse effect on hatchability, feed efficiency, and survival rate.


2014 ◽  
Vol 14 (1) ◽  
pp. 101-115 ◽  
Author(s):  
Alessandro Agazzi ◽  
Erica Tirloni ◽  
Simone Stella ◽  
Serena Maroccolo ◽  
Barbara Ripamonti ◽  
...  

AbstractThe aim of this study was to evaluate the effects of the administration of a species-specific probiotic (Lactobacillus animalis SB310, Lactobacillus paracasei subsp. paracasei SB137 and Bacillus coagulans SB117 in a 30:35:35 ratio, respectively; 1.8 × 1010 CFU/g of powder) on gut microbial balance, immune response and growth performance of Holstein female calves during the first month of life. Twenty-two calves were divided into two experimental groups from 2 to 28 days of life: control (C), fed with milk replacer and concentrate as a basal diet, and treatment (T), fed C diet plus 1 g/calf/day of probiotic powder for the first month of age. Faecal and blood samples were individually collected and analysed weekly. Individual faecal score was recorded daily and general health score was calculated at the end of the trial. Cell-mediated immune response was evaluated by skin test at 7 and 28 days of life. Milk replacer and concentrate intake were recorded daily, while body weight and biometrical parameters were recorded at 2, 8, 14, 21 and 28 days of life, thus average daily gain and feed conversion rate were calculated. During the first week of treatment, lower blood eosinophil percentage (0.05% vs. 0.22%; P≤0.01) was found in T group, while basophils were higher in T than C group at the end of the trial (0.21% vs. 0.16%; P≤0.05). Higher faecal lactic acid bacteria (LAB)/E. coli ratio on day 28 of life (3.73 log CFU/g vs. 2.02 log CFU/g; P≤0.05) and lower incidence of diarrhoea were found in the treated group (63.30% vs. 70.71%; P=0.05). Body weight (48.92 kg vs. 46.92 kg; P≤0.05), total concentrate intake (14.77 kg vs. 12.56 kg on dry matter basis; P≤0.05), and heart girth (81.16 cm vs. 78.49 cm; P≤0.05) were significantly higher in T group. The administration of the probiotic during the first month of life improved gut microbiota and increased the growth performance and some biometric parameters of calves.


Author(s):  
MM Rahman ◽  
NR Sarker ◽  
MA Alam

This study was carried out to evaluate the feeding effect of high yielding fodders (HYF) on feed intake and growth performance of growing Hilly Brown Bengal (HBB) goat. For this purpose, a feeding trail was conducted with 16 growing HBB kids (4 to 5 months) by dividing equally in four groups having four replicates for a period of 75 days. The goats in group T0 (control) received natural grass along with 101.30g concentrates and adlibitum cowpea hay, whereas in group T1, T2 and T3, only natural grass was replaced by BLRI Napier 3, BLRI Napier 4 and Ruzi fodder, respectively. Total dry matter intake (DMI), roughages DMI, crude protein intake (CP), body weight gain (kg), average daily gain (g) and forth night body weight gain (g/day) were studied. Results revealed that, DMI (288.39, 285.71, 293.48 and 301.35 g/day in group T0, T1, T2 and T3, respectively), body weight gain (3.60, 3.74, 3.73 and 3.77 kg in group T0, T1, T2 and T3, respectively), average daily gain (47.32, 49.16, 49.12 and 48.92 g in group T0, T1, T2 and T3, respectively) and feed conversion ratio (6.2, 5.9, 6.0 and 6.1 in group T0, T1, T2 and T3, respectively) of HBB kids were not differed significantly (P>0.05) for all the treatment groups. The DMI from roughages (196.2, 193.5, 201.3 and 209.2 g/day in group T0, T1, T2 and T3, respectively) and CP intake (38.7, 42.1, 48.3 and 38.8 g/day in group T0, T1, T2 and T3, respectively) were significantly varied (P<0.05), while highest CP intake was found in the treatment group T2. Forthnight body weight (g/day) was not significantly (P>0.05) gained with feeding of HYF for all the treatment groups. From this study, it can be concluded that, growing HBB kids could equally be supplied with either BLRI Napier 3 or BLRI Napier 4 or Ruzi fodder in addition to ad libitum cowpea hay for better voluntary feed intake and growth. Bang. J. Livs. Res. Vol. 27 (1&2), 2020: P. 73-81


2019 ◽  
Vol 97 (11) ◽  
pp. 4619-4624
Author(s):  
Sandra J A van Kuijk ◽  
Marc Jacobs ◽  
Coen H M Smits ◽  
Yanming Han

Abstract The current study compared the effect of hydroxychloride trace minerals (HTM) with the effect of inorganic trace minerals (ITM) on growth performance and carcass quality in grower-finisher pigs. The results of 6 studies conducted throughout Europe were combined into one meta-analysis. All included studies were performed using pigs from about 19 kg of body weight until slaughter. In all studies, 2 different mineral sources were compared, HTM and sulfates as ITM. Zn from either HTM or ITM was added at a level of 80 ppm to the diet, and Cu was added at a level of 15 ppm from the same source as Zn. In most studies, an additional treatment was included in which 20 ppm Zn was used from either source in combination with 15 ppm Cu from the same source. Diets were fed in 3 phases according to local commercial standards. The body weight, average daily gain, average daily feed intake, and gain:feed ratio were measured at the end of each phase. At the end of each study, the carcass yield, back fat thickness, and lean meat percentage were measured at commercial slaughterhouses. The meta-analysis was conducted using a MIXED model in SAS taking into account the within-study and between-study variation. The comparison was done only between HTM and ITM added at the same Zn level. No statistical differences were observed for growth performance or carcass characteristics between the mineral sources in pigs fed 20 ppm Zn. When 80 ppm Zn was used, a significant improvement in lean meat percentage was observed in pigs fed HTM compared with pigs fed ITM. In the overall study period, there was a tendency towards an increased gain:feed ratio in pigs fed 80 ppm Zn from HTM. In the last feeding phase, before slaughter gain:feed ratio and average daily gain were both significantly improved by 3.9%. In conclusion, HTM addition improved growth performance and lean meat percentage in grower-finisher pigs.


Animals ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1598
Author(s):  
Junjing Xue ◽  
Liang Xie ◽  
Bo Liu ◽  
Liyuan Zhou ◽  
Yajun Hu ◽  
...  

Epidermal growth factor (EGF) plays an important role in nutrients absorption. However, whether it can be an effective additive to improve the growth performance and nutrients absorption in lipopolysaccharide (LPS) challenged early weaning piglets is still unknown. A 14-days trial was conducted to investigate how EGF attenuates the effect of LPS on the growth performance, nutrient digestibility, microelement absorption of early-weaned pigs, and study the underlying mechanism. A total of 48 early weaned piglets, aged 25 days, were randomly distributed to four groups (control, EGF, LPS and EGF + LPS groups) consisting of a 2 × 2 factorial design. The main factors were the level of LPS (HLPS = high LPS: 100 μg/kg body weight; ZLPS = low LPS: 0 μg/kg body weight) and EGF (HEGF = high EGF: 2 mg/kg diet; ZEGF = low EGF: 0 mg/kg diet). Each group had four replicates and each replicate consisted of three piglets. The results showed that piglets injected with HLPS level significantly decreased the average daily gain (ADG), and significantly increased the feed conversion ratio (FCR) compared with the piglets injected with ZLPS level, while piglets fed HEGF level significantly increased the average daily feed intake (ADFI) compared with the piglets fed ZEGF level (p < 0.05). Piglets injected with HLPS level significantly decreased the apparent digestibility of crude fat compared with the piglets injected with ZLPS level (p < 0.05). Piglets injected with HLPS level significantly increased the concentration of most microelements in the gastrointestinal tract chyme and feces, and significantly decreased the expression levels of most microelement transport-relative genes in the mucosa of gastrointestinal tissues compared with the piglets injected with ZLPS level (p < 0.05). Piglets fed HEGF level significantly decreased the concentration of microelement in the gastrointestinal tract chyme and feces, and significantly increased the expression levels of the microelement transport-relative genes in the mucosa of gastrointestinal tissues compared with the piglets fed ZEGF level (p < 0.05). In conclusion, dietary EGF could attenuate the negative effect of LPS exposure on the apparent digestibility of crude fat and microelement absorption of early-weaning piglets. EGF and LPS influenced the absorption of essential trace element through changing the expression levels of microelement transport-relative genes in the mucosa of gastrointestinal tissues. In the early weaning piglets, EGF can be used as an additive to increase the essential trace elements absorption.


2021 ◽  
Author(s):  
Abdolhamid Karimi ◽  
Mohammad Javad Abarghuei ◽  
Alidad Boostani

Abstract In this investigation, performance, feed efficiency and carcass traits of 48 weaned crossbred Grey Shirazi × Ghezel and purbred Grey Shirazi fattening lambs (mean live weight, 28.5 ± 0.5 kg and age, 115 ± 5 days) were evaluated. Lambs were divided into 4 groups contain the GM group (12 purebred male lambs of Grey Shirazi ewe × Grey Shirazi ram), the GF group (12 purebred female lambs of Grey Shirazi ewe × Grey Shirazi ram), the CM group (12 crossbred male lambs of Grey Shirazi ewe × Ghezel ram) and the CF group (12 crossbred female lambs of Grey Shirazi ewe × Ghezel ram). The dry matter intakes (DMI), average daily gain (ADG) and carcass traits in the lambs were determined. The DMI was greater in CF lambs compared to GF lambs (P < 0.001). Feed conversion ratio (FCR) was higher in male lambs comparing to female lambs (P = 0.001). The final body weight, ADG, live weight at the slaughtering and hot carcass weight (HCW) were lower in GF lambs compared to another lambs (P < 0.001, P = 0.003). Cold carcass weight (CCW) in CM lambs was higher than in other groups. The Longissimus dorsi (LD) area was higher in crossbreed male lambs (P = 0.001). Crossbreeding improved grow performance (final body weight and ADG) in male and female lambs. Carcass trait was improved by crossbreeding especially in male lambs. Sex effect on growth performance and carcass traits was noticeable and male lambs had superior growth.


2019 ◽  
Vol 97 (Supplement_2) ◽  
pp. 73-73
Author(s):  
Rafael A Cabrera

Abstract The objective of this study was to compare Activo Liquid supplemented via the water agaisnt Mecadox 50 on nursery pigs’ growth performance and survival. Activo Liquid is a combination of secondary plant compounds plus organic acid (antimicrobial) supplemented in the water to support gut health and improve performance. The study design of this trial was a Split Plot with 36 replicates (9 replicates/treatment) with 10 pigs/pen. Pigs were allotted by a Randomized Complete Block Design by weight at weaning. Pigs were around 5.7 kg and 19 days of age average on body weight and weaning age, respectively. The nursery houses were not washed for two turns to expose the animals to serious pathogens. The data were analyzed by analysis of variance with pen as the experimental unit. Significant differences were established by P < 0.05. Treatments were Control with 50g/ton of Mecadox for all nursery phases and three Activo Liquid treatments (6 oz per 128 gallon of drinking water administered either for 3, 5 or 7 days post-weaning). A typical nursery feeding program was followed: Phase 1 from d 0 to d 7, Phase2 from d 8 to d 21 and Phase 3 from d 22 to d4 2. They contain 23%, 21% and 19% crude protein respectively. The results showed no significant difference on final body weight among the treatments. All Activo treatments had improved (P < 0.05) feed conversion (Feed:Gain) when compared with the medicated treatment. Activo Liquid 5d treatment post-weaning had numerically lower mortality when compared with all the other treatments. In conclusion, the results of this trial showed that the supplementation of Activo Liquid for 5 d post-weaning at 6 oz/128 gallon of water can safely replace Mecadox 50 g/ton. More research is needed to validate the repeatability of these results and understand Activo Liquid’s mode of action as a powerful antimicrobial.


Author(s):  
Lukáš Bujňák ◽  
Pavel Naď ◽  
Iveta Maskaľová ◽  
František Zigo

This study was conducted to investigate the influence of replacing part of soybean meal (SBM) with 15% treated rapeseed meal (tRSM) on growth performance, blood parametres and nutrient digestibility in young growing pigs. A total of 12 crossbred growing pigs (Slovakian White x Landrace) with an average initial body weight of 15.70 ± 1.83 kg were divided into two dietary treatments according to their body weight and sex (six pigs in each group). The experiment lasted 34 days. The rapeseed meal was treated with the product that neutralizes the negative effects of glucosinolates contained in rapeseed by-products for pigs feeding. In our study, we did not observe negative effects of tRSM on body weight, average daily gain and feed conversion ratio. In blood profile, serum urea, albumin, glucose and total chlosterol were not influenced by dietary tRSM treatment. Concentration of total proteins was decreased at the end of the experimental period in the experimental group (P<0.01). For apparent total tract digestibility acid-insoluble ash was used as marker. Partially replacing of SBM with tRSM had no significant negative effects on the apparent total tract digestibility of dry matter, crude protein and crude fat. Finally, the inclusion of 15% of treated RSM in growing pig diets had no negative effects on growth performance, nutrients digestibility and selected blood characteristics.


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