One Step Forward, Two Steps Back

2014 ◽  
Vol 10 (1) ◽  
pp. 1-15 ◽  
Author(s):  
Stephan Engelkamp ◽  
Katharina Glaab ◽  
Judith Renner

AbstractIn their response to our article »Office Hours«, Nicole Deitelhoff and Lisbeth Zimmermann issue three major points of critique towards our proposal of a critical approach to norm research: They criticize, firstly, our discussion of constructivist norm research, secondly, our use of the concepts of local and Western and, thirdly, the overall critical potential of our proposed approach, which they criticize as going merely beyond an unmasking gesture. We take our response to our critics, firstly, as an opportunity to clarify some of the arguments made in our article. Secondly, we confront the points of criticism outlined above and show that Deitelhoff’s and Zimmermann’s critique can only be maintained if one accepts their specific reading of our article. Moreover, it gets tangled up in three major contradictions and is built upon a problematic understanding of the relation between empirical facticity and normative evaluation.

2007 ◽  
Vol 336-338 ◽  
pp. 498-501
Author(s):  
Xian Feng Jiang ◽  
Min Fang Han ◽  
Su Ping Peng

The all processes for manufacturing materials parts of solid oxide fuel cell (SOFC) are discussed in the paper. The films are made in one step by the ways of APS, VPS, EVD, which are usually used to produce the electrolyte and interconnect. The films are thin and good gas-resistance, but with relatively high cost. All parts of SOFC are made by the following ways, such as sol-gel, tape casting, tape calendaring and screen printing, which are suitable for manufacturing samples in industry with the cheapest process by co-sintered together ways.


2009 ◽  
Vol 1209 ◽  
Author(s):  
Georgios A. Sotiriou ◽  
Adrian Camenzind ◽  
Frank Krumeich ◽  
Andreas Meyer ◽  
Sven Panke ◽  
...  

AbstractSilver clusters (4-150 nm) anchored on nanostructured silica particles (300-400 m2/g) with closely controlled Ag content and size were made in one-step by scalable flame spray pyrolysis of Ag-nitrate and hexamethyldisiloxane containing solutions. Composite Ag/SiO2 nanoparticles were characterized by S/TEM, EDX spectroscopy, X-ray diffraction, N2 adsorption. The activity of such nanoparticles against the Gram negative bacterium Escherichia coli was investigated by monitoring the recombinantly synthesized green fluorescent protein. It is shown that higher Ag content particles exhibit a stronger antibacterial effect.


Author(s):  
Barbara Korth

This paper uses the findings of a critical ethnography studying the interactions of adult colleagues (Korth, 1998) to propose a critical approach to care theory and research. The argument proceeds from Jaggar's (1995) critique of the scholarship on care. Her criticism voices concerns regarding the lack of attention to the justificatory potential of care research/theory and the over-dependence on particularities. This paper provides one set of responses capable of addressing these concerns and of reformulating the concerns into a more complex conceptualization of care. The resulting analysis implies a theory of care as a pragmatic-communicative construct, one that is more precise, but compatible with the interpersonal rationality to which Noddings (1991) attributes caring. Care emerges as a communicative act with a complex but definitive horizon structure. Care did not reconstruct from on-going interactions as a simple intention, nor a feeling, nor anything extra-rational or non-rational. This approach to understanding caring locates Jaggars concerns within the interpretive life of interactants. The papers specific contributions include exemplifying a refined analysis of care-in-action, articulating a meta-theory useful for the theory and study of care, introducing a typology of caring acts, demonstrating the critical potential of care research, and illustrating the connection between critique and justification.


2007 ◽  
Vol 54 (2) ◽  
pp. 29-32 ◽  
Author(s):  
M. Jovanovic ◽  
M. Colic ◽  
L. Rasulic ◽  
M. Stojicic ◽  
M. Malis

Reconstruction of the nose is very old surgical procedure and, in fact, represents the beginnings of plastic surgery. In reconstruction, an effort has to be made in order to achieve a normal look. A surgeon must choose carefully the method of reconstruction, taking into consideration the skin color, texture and nasal topography. Full-thickness nasal defects in alar region are very difficult for reconstruction due to anatomic characteristics and structures, which are very important for normal breathing and cosmetic result. Our study analyzed 16 patients with full-thickness defect of alae nasi. Folded nasolabial flaps were used for reconstruction of these defects. Good results were achieved in all cases. The flap was vital. No flap necrosis was reported in any of these patients. The lining of the nose was good. Postoperatively, the alar edge was thickened, but it became thinned after six months. The incision in donor?s region was well placed in the natural line of nasolabial fold. It was concluded that folded nasolabial flap was extremely good one-step procedure for reconstruction of full-thickness defects of alar region. .


2020 ◽  
Vol 19 (2) ◽  
pp. 136-151
Author(s):  
Shivani Singh ◽  
Meenakshi Dhanawat ◽  
Sumeet Gupta ◽  
Deepak Kumar ◽  
Saloni Kakkar ◽  
...  

: Alzheimer’s disease (AD) is a multifarious and developing neurodegenerative disorder. The treatment of AD is still a challenge and availability of drug therapy on the basis of symptoms is not up to the mark. In the context of existence, which is getting worse for the human brain, it is necessary to take care of all critical measures. The disease is caused due to multidirectional pathology of the body, which demands the multi-target-directed ligand (MTDL) approach. This gives hope for new drugs for AD, summarized here in with the pyrimidine based natural product inspired molecule as a lead. The review is sufficient in providing a list of chemical ingredients of the plant to cure AD and screen them against various potential targets of AD. The synthesis of a highly functionalized scaffold in one step in a single pot without isolating the intermediate is a challenging task. In few examples, we have highlighted the importance of this kind of reaction, generally known as multi-component reaction. Multi-component is a widely accepted technique by the drug discovery people due to its high atom economy. It reduces multi-step process to a one-step process, therefore the compounds library can be made in minimum time and cost. This review has highlighted the importance of multicomponent reactions by giving the example of active scaffolds of pyrimidine/fused pyrimidines. This would bring importance to the fast as well as smart synthesis of bio-relevant molecules.


1989 ◽  
Vol 9 (9) ◽  
pp. 4052-4055
Author(s):  
S Fotheringham ◽  
W K Holloman

We have demonstrated that genes from Ustilago maydis can be cloned by direct complementation of mutants through the use of genomic libraries made in a high-frequency transformation vector. We isolated a gene involved in amino acid biosynthesis as an illustrative example and showed that integrative and one-step disruption methods can be used to create null mutations in the chromosomal copy of the gene by homologous recombination. The results of this investigation make it clear that one-step gene disruption will be of general utility in investigations of U. maydis, since simple, precise replacement of the sequence under study was readily achieved.


2017 ◽  
Vol 117 ◽  
pp. 167-175
Author(s):  
E. V. Chefranov ◽  
E. Yu. Fedorenko ◽  
R. V. Krivobok ◽  
G. V. Lisachuk ◽  
I. A. Gusarova

The results of the study of samples of radiotransparent ceramics based on the system SrO—BaO—Al2O3—SiO2 which have been made in one-step and two-step process have been presented. A comparative analysis of their sintering characteristics and dielectric properties have shown that materials which were obtained by a two-stage process are characterized by a relatively high degree of sintering (W = 2..72 ÷ 3.97 %, Papp = 2901 ÷ 3180 kg/m3), sufficient values of dielectric losses tangent (tgδ = 0.000258 ÷ 0.000313), however, their dielectric permittivity (ε = 12.11 ÷ 14.38) don’t reach the specified level. It was concluded that it is necessary to modify the compositions of the basic oxide system using small additives that intensify sintering and provide high-temperature stability of solid solutions of slawsonite and celsian.


2008 ◽  
Vol 8 (2) ◽  
pp. 208-234 ◽  
Author(s):  
Roberto A. Valdeón

This paper presents a critical approach to the translation of cultural items in the Spanish dubbed version of the American sitcom Will & Grace. The paper starts with a presentation of domestication and foreignization (Venuti 1995). The former is discussed in connection with the choices made in the target texts. I, then, introduce the term “alienation” as another strategy used to render culture specificities. In the second section I examine the key comical elements present in the scripts, in which cultural allusions also play a significant role. Section three explores how these culturally anchored lexical items are rendered in the Spanish version, establishing a taxonomy that includes preservation of international items, preservation of culture-specific items, substitution with a different source-culture item, substitution with an international item, substitution with a target-culture item, substitution with corrupted forms of target-culture items and substitution with a superordinate. The use and translation of expletives as elements unique to a language and culture are also covered. The final section discusses the transition from domestication to alienation.


2002 ◽  
Vol 45 (11) ◽  
pp. 133-144 ◽  
Author(s):  
K. Goss

Ongoing deterioration of the riverine environments of the Murray-Darling Basin led the Murray-Darling Basin Ministerial Council to introduce a Cap in 1995 to halt the growth in diversions of water for consumptive use. This initiative recognised the finite nature of water resources in the Basin and sought to introduce a balance between off-stream use of water and protection of the riverine environment. But the cap is only one step, albeit a fundamental one, in restoring the Basin's rivers - it is a “stake in the ground”. Parties to the Murray-Darling Basin Initiative recognise the need to reverse decades of creeping decline if the Basin's rivers and riverine environments are to return to a more ecologically sustainable condition. In the last 12 months, Council and Commission have taken far-reaching decisions designed to restore the Basin's Rivers. Many of these decisions, even 10 years ago, would have been unimaginable. The Report Card will explain the need for a number of recent decisions that will impact on the future of the Basin's rivers. For example, Council's decision to establish an Environmental Manager function in the Office of the Commission was made in the context of the recently agreed Integrated Catchment Management (ICM) Policy, and supporting Sustainable Rivers Audit. The role of targets and accountabilities under the ICM Policy will also be discussed. The Report Card will also present a snapshot of the state of the Basin's rivers and the actions being taken at a range of scales and locations in response to identified problems. Because some of the key initiatives are still in development, this Report Card will set the scene by describing where our attention is being focused and why.


2016 ◽  
Vol 256 ◽  
pp. 314-318 ◽  
Author(s):  
Hong Xing Lu ◽  
Qiang Zhu ◽  
You Feng He ◽  
Fan Zhang ◽  
Da Quan Li

The semi-solid casting process has a lot of advantages in controlling casting defects. High quality impellers have been produced successfully by the semi-solid process for several years. The semi-solid processed impellers have uniform microstructure and premier mechanical properties, and therefore excellent durability. Further improvement of performance of the impellers is demanded and achieved by increasing curvature and length of blades of impellers. These changes create potential trend of casting defects in blades of impellers, such as non-filling holes. In our recently work, castings were made in different conditions, including two-step plunger velocity and one-step plunger velocity. The experimental results show that the change of plunger velocity played a decisive role in the forming of non-filling holes. Entrapped gas is the direct reason of the non-filling holes. With the increasing of plunger velocity, the area of non-filling holes increased. The non-filling holes in blades could be avoided by eliminating the plunger velocity’s changing during filling blades.


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