ENDOCRINE CHANGES BEFORE AND AFTER THE MENARCHE

1973 ◽  
Vol 74 (4) ◽  
pp. 695-702 ◽  
Author(s):  
B.-A. Lamberg ◽  
R.-L. Kantero ◽  
P. Saarinen ◽  
O. Widholm

ABSTRACT In an endocrine survey of healthy girls aged 8 to 20 years before and after the menarche the serum TSH was measured by radioimmunoassay along with some parameters of thyroid function which are described separately. The subjects were grouped according to the skeletal age (SA) until the menarche and after this in the post-menarcheal age (PMA) expressed in years. The TSH value was highest in the youngest age group and from then on decreased. However, within 0.5 years after the menarche another significantly elevated TSH peak occurred. There was no significant difference between the means for TSH before (5.4 μU/ml) and after the menarche (5.7 μU/ml). Both values, however, as well as the means for almost all the individual age groups, were significantly higher than the mean for 13 boys aged 12 to 16 years (3.9 μU/ml) and that for normal adults (3.6 μU/ml). When the girls were grouped according to the stage of puberty, the TSH peak at the time of menarche disappeared. When they were grouped according to SA, a gradual declining trend was seen from age 8 to 16 years. It is concluded that the maturation process in girls in some way involves a significant elevation of serum TSH and an increase in the total and free T4 level which is not dependent on binding proteins.

2019 ◽  
Vol 56 (1) ◽  
pp. 10-14 ◽  
Author(s):  
Fangio FERRARI ◽  
Elisa Cantú Germano DUTRA ◽  
Henrieli Correia ZANARDI ◽  
Bruno Lorenzo SCOLARO ◽  
Odemari Miranda FERRARI

ABSTRACT BACKGROUND: The bacterium Helicobacter pylori is strongly associated with the development of gastric adenocarcinoma. Currently, the prevalence in developed countries is 40%, but this value increases considerably in developing countries, which can reach rates bigger than 90%. OBJECTIVE: The objective of this study was to determine the mean and annual prevalence of Helicobacter pylori infection in patients from Itajaí during the period from July 1992 to April 2016, as well as the gender and age groups most affected. METHODS: After consent of the clinical director of the Gastroclinica Itajaí and confidentiality commitment about the research, the database of the Endoscopy Service of the clinic was evaluated. All the patients who underwent their first upper digestive endoscopy with urease test and/or histological analysis were included. The data were submitted to statistical analysis of prevalence by gender, age group and years of study, with subsequent correction through the confidence interval. RESULTS: The mean prevalence of Helicobacter pylori infection thru all years of study was 50.07%. With the calculation of the annual prevalences, it was evident the gradual reduction of infection in the population of Itajaí, that was 81.3% in 1992, declining to 33% in the year of 2016. When classifying the prevalence of infection by gender, it was higher in males (53.59%), and gender distribution by age group showed no statistically significant difference among genders between the ages of 40 and 80 years. In relation to the age group, the highest prevalence was in the group between 40 and 49 years. CONCLUSION: Although this study is retrospective and based on endoscopic database analysis, without access to clinical data of patients such as prior use of proton pump inhibitor and antibiotics to endoscopy, its results are important because they may reflect the current panorama of Helicobacter pylori infection in the city under study, where it has been presenting a gradual reduction of prevalence over the years, with current rates similar to that of developed countries (33%). Future studies are needed to confirm our data.


2003 ◽  
Vol 27 (1) ◽  
pp. 91-94 ◽  
Author(s):  
Ali Mentes ◽  
Julide Atukeren

The aim of the study was to evaluate toothbrushing management and ability of children in relation to age and gender. The study population consisted of 75 children and were divided into three equal groups as 3-5, 6-8 and 9-11 years of age.The grip type during toothbrushing was recorded on videotape.The most preferred grip types were distal (73%) followed by power (43%) and oblique grips (29%). There were a statistically significant differences between age groups and the grip types (p<0.001) but no significant difference was seen between boys and girls in grip preferences (p>0.05).The mean duration of toothbrushing was shorter in 3-5 years of age group (28 seconds) than the 6-8 and 9-11 age groups (35 and 47 seconds respectively).


Author(s):  
Dr. Sheetal Gupta ◽  
Dr. Anita Gupta ◽  
Dr. Sushmita Ahirwal

Visual perception is the process by which individuals assign meaning, understanding, and interpretation to what they have seen. The aim of this study was to determine the visual perceptual skills of typically developing Indian children on MVPT-4. A sample of 180 typically developing Indian students were included in the study using convenience sampling method. They were divided in six age groups with age ranging from 6years to 12 years with 30 children in each age group. It was found that visual perceptual skills of typically developing Indian children in 6-12 years of age group can be assessed using MVPT-4. Analysis was done using One-way Anova to compare the mean raw score of each age group. There was a significant difference between the age groups at statistical value of p< 0.001. The score improved with age, signifying refined and matured visual perceptual skills in older children. Age influences visual-perceptual skills of these children. This study also provides a foundation for further researches and highlights the importance of MVPT-4 as a screening tool to be used by the occupational therapist in order to assess the visual perceptual skills of children.


2021 ◽  
Vol 5 (1) ◽  

Purpose: The goal of this study was to determine age-relatedvariation in the thickness of the corneal epithelium using ultrasound pachymeter. Methods: One hundred three patients were enrolled in this study and grouped according to age: Group A (< 30 years), group B (31-40 years), group C (41-50 years), group D (51-60 years), group E (61-70), and group F (> 71). Total corneal and corneal epithelial thickness measurements were made using the SonogageCorneo-Gage Plus 2 (Cleveland, Ohio) ultrasound pachymeter. Correlations of central epithelial thickness with central total corneal thickness, age, and gender were calculated. In addition, mean central epithelial thickness (CET) was measured. One-way ANOVA testing and post hoc analysis with the Tukey test and Pearson correlation were performed to analyze data. Results: The mean epithelial thickness at the central cornea was 47.88±1.15 μm, with no statistically significant difference between right and left eyes, and no significant differences in gender or central total corneal thickness. The difference in mean epithelial thickness across age groups was statistically significant (p <0.008). The mean epithelial thickness of the > 71 years group was significantly thinner than that of the < 30 years, 31-40, 41-50, and 51-60 years age groups. Conclusions: Ultrasound pachymeter of the corneal epithelium demonstrated that the oldest age group (> 71 years) had significantly thinner central corneal epithelial thickness than the younger age groups. There was no correlation between epithelial thickness, total corneal thickness, gender, or laterality.


2021 ◽  
Vol 9 (A) ◽  
pp. 1117-1122
Author(s):  
Sherif Shafik El-Bahnasy ◽  
Magdy Youakim ◽  
Mohamed Shamel ◽  
Hisham El Sheikh

AIM: The purpose of the study was to measure and compare the prevalence of mandibular canal (MC) location variations in regard to mandibular first molars in both genders at different age groups. METHODS: A retrospective study was performed on 80 cone-beam computed tomography scans. Distance between MC and apical apices of first molars, buccal and lingual cortical plates was measured in both sides. RESULTS: 80 scans with 160 sides were analyzed. Distances was measured bilaterally for all scans with mean (5.22 ± 0.77) in men versus (4.1 ± 0.7) in women at group age 31–40 apical to apices of first molars. The mean was (3.77 ± 0.62) in men versus (2.81 ± 0.47) in women at same age group at buccal side, lingually the mean was (4.02 ± 0.67) in men versus (3.67 ± 0.26) in women in the same age group. CONCLUSION: Our study showed that there were decrease in measurements in older age group in both genders and in female groups more than male groups but with no statistical significant difference.


2016 ◽  
Vol 15 (1) ◽  
pp. 118-122
Author(s):  
Vidya Bhagat

Background: The Psychotherapy can be effective in prolonging periods free of depression in early senescent has been focused on the study. People refused medication agreed to come for psychotherapy are treated to get free from their depressive symptom. The main objective of the study was therefore using psychotherapy as a treatment module to stretch time free of depression. Further psycho education to give more information on depression and increase patient flexibility for the combination of anti-depressant with psychotherapy when needed.Methodology: The subjects selected for the study were 60 patients from ‘Nitte Rural Psychiatry Clinic’ Nitte Mangalore Karnataka, India. They were selected by random sampling technique. Medico-Psychological questionnaire for general neuroticism was administered to find out the extent of depression before and after psychotherapy. To find the difference between the age and depression before and after psychotherapy Carl Pearson’s Correlation coefficient method was carried out.Results: The results reveal that a non-significant difference between age groups with extent of depression in different age group of early senescent before and after psychotherapy (Chi-square=1.7913, p>0.05) at the 5 % level of significance and (Chi-square=2.4485, p>0.05) at the 5 % level of significance respectively. Further the Comparison of extent of depression before and after psychotherapy in 50-55, 56-60 age groups and as a total by Wilcoxon matched pairs test has been administered and the result reveals that significant differences between extent of depression before and after psychotherapy in 50-55yrs of age group (Z=2.5205, p<0.05) at the 5 % level of significance, 56-60yrs of age group (Z=2.2014, p<0.05) at the 5 % level of significance. It means that, the significant means that, the significance of 15.7%, 10.5%depression was decreased before and after psychotherapy respectively. A significant difference was observed between extent of depression before and after psychotherapy in 50-60yrs of age group (Z=3. 2958, p<0.05) at the 5 % level of significance. It means that, the significance of 13.0% depression was decreased after psychotherapy.Conclusion: The implication of this study was to develop insight and understanding among the clinicians that importance psychotherapy as treatment of depression.Bangladesh Journal of Medical Science Vol.15(1) 2016 p.118-122


2010 ◽  
Vol 95 (8) ◽  
pp. 3675-3683 ◽  
Author(s):  
Rebecca Over ◽  
Sonia Mannan ◽  
Hala Nsouli-Maktabi ◽  
Kenneth D. Burman ◽  
Jacqueline Jonklaas

Context: Some studies suggest altered pituitary functioning and TSH production with aging. Objective: Our objective was to test the hypothesis that less TSH production occurs despite comparable hypothyroxinemia with advancing age. Design: We retrospectively studied adult outpatients of all ages with confirmed hypothyroidism and documented their TSH and free T4 concentrations. Participants: Two populations of 112 patients were subdivided into four age groups: 1) patients newly diagnosed with primary hypothyroidism and 2) thyroid cancer patients undergoing l-T4 withdrawal in preparation for diagnostic or therapeutic radioiodine. Main Outcome Measure: The relationship between paired free T4 and TSH concentrations and patient age was studied. Results: With spontaneous hypothyroidism, the mean TSH concentration decreased nonsignificantly in each ascending age group with comparable free T4 (FT4) concentrations (&lt;35 yr, 69 mIU/liter; 35–49 yr, 49 mIU/liter; 50–64 yr, 43 mIU/liter; &gt;64 yr, 29 mIU/liter). With iatrogenic hypothyroidism, the mean TSH concentration decreased significantly in each ascending age group (&lt;35 yr, 156 mIU/liter; 35–49 yr, 115 mIU/liter; 50–64 yr, 74 mIU/liter; &gt;64 yr, 46 mIU/liter; P &lt; 0.001) despite similar FT4 concentrations. The relationship between the log-transformed TSH and FT4 was significantly and inversely affected by age in multivariate analyses in both spontaneous hypothyroidism (P = 0.0005) and in iatrogenic hypothyroidism (P &lt; 0.0001). Conclusions: Age modifies the pituitary set point or response to comparably reduced free T4 concentrations, resulting in lesser serum TSH elevation in older individuals. This phenomenon occurs with both spontaneous and iatrogenic hypothyroidism. This may be an adaptive response in normal aging or a pathological alteration of pituitary function with age.


2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Gelaye Gebisa ◽  
Kibiru Beriso ◽  
Biruk Bogale ◽  
Oda Gizaw ◽  
Dawit Chala

Trypanosomosis is one of the most economically challenging diseases affecting mammals, and it is a serious haemoprotozoan disease caused by different species of unicellular eukaryotic parasite of the genus trypanosome. The study was conducted to access the prevalence of bovine trypanosomosis, its associated risk factors, and vector density on cattle reared in three selected districts, namely, Chewaka, Dabo Hana, and Meko districts. Blood was collected from a total of 1046 cattle of age groups extending from 1 to 6 years. The buffy coat technique was used to check the presence of parasites from sampled blood, and the trypanosome species were identified using Giemsa-stained thin blood films. The packed cell volume of sampled blood was determined using the haematocrit. A total of 160 traps were deployed to study the entomological survey. Generally, 3.44% of the studied animal was infected with trypanosomosis, and T. vivax was the dominant species of trypanosomosis in the study areas. Significant differences (P < 0.05) were observed due to associated factor viz. body condition and anaemic status of the animal; however, insignificant differences were also recorded between different districts, age group, and sex. The mean PCV value of parasitaemic and aparasitaemic animals was 22.22 ± 0.92 and 26.18 ± 0.16, respectively, and significant difference was P < 0.05. An overall of 1.82 flies per trap per day was recorded from the study areas, and among the total caught vectors, 81.4% of it was G. tachinoides and the rest was G. morsitans. Therefore, the veterinarians have to continue providing the appropriate medication/treatment for the infected animals per appropriate recommendation, and Bedele NTTICC has to take more measures to control the density and distribution of tsetse flies in Dabo Hana district than the others due to high flies per trap per day observed in Dabo Hana district.


2008 ◽  
Vol 2 ◽  
pp. 24-27
Author(s):  
Md Shibbir Ahmed ◽  
Mohsin Khalil ◽  
Md Babibur Rahman ◽  
Sabina Mannan ◽  
Seheli Zannat Sultana ◽  
...  

The morphological study was done to see length, breadth and thickness of the ovary in different age group of Bangladeshi people to increase the knowledge regarding variational anatomy in our population. Sixty two postmortem tissue block containing ovary and fallopian tube along with surrounding structures were collected from 62 female cadavers of different age groups and fixed in 10% formol saline solution. Gross & fine dissections were carried out to study these morphological parameters of ovary in different age group. In the present study, findings were compared with the finding of other researchers.In this study the mean length of ovary was maximum in found in group C (46-80 years) 4.32cm and minimum was found in group A (2-13 years) 2.81cm of both side. The mean breadth of ovary was maximum in group C 2.01cm and minimum was in group A 1.38cm. The mean thickness of ovary maximum was in group C 0.971cm and minimum was in group A 0.682cm of both sides. In statistical analyses significant difference between two groups was calculated by using students ‘t' test. A difference between two groups was considered to be significant when p


2021 ◽  
Vol 45 (3) ◽  
pp. 216-220
Author(s):  
Syed Aliya ◽  
Harsimran Kaur ◽  
Nishita Garg ◽  
Rishika ◽  
Ramakrishna Yeluri

Objective: To evaluate the clinical maximum mouth opening in children and its correlation with age, and sex. Study Design: Three hundred children of age 6–12 years, from different schools of Moradabad city were included. The participants were divided into three groups based on their age i.e Group 1 (n=100) 6–8 years, Group 2 (n=100) 8–10 years and Group 3 (n=100) 10–12 yrs. Three recordings of maximum mouth opening (MMO) were obtained using digital vernier caliper and the mean of three was considered as the MMO of that child. The data was analyzed using Spearman correlation, ANOVA with post- hoc Bonferroni test. The significance level was predetermined at p≤0.05 .Results: The mean MMO for children of Moradabad of aged 6–8yrs in boys is 39.87 ± 4.91 mm and in girls is 36.85± 4.09 mm. In 8–10 yeas age group, the MMO in boys is 44.5± 5.1 mm and in girls 41.77± 5.24 mm. In 10–12 year age group, the MMO in boys is 49.63± 5.56 mm and in girls is 49.33±5.32 mm respectively. The MMO was found to be higher in boys in all the three age groups. Conclusions: There was a significant difference in values of MMO in all the three age groups with boys having higher MMO values when compared to girls. Varying range of MMO values was observed within three age groups.


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