scholarly journals Antibiotic treatment and resistance in chronic wounds of vascular origin

2016 ◽  
Vol 89 (3) ◽  
pp. 365-370 ◽  
Author(s):  
Valentina Tzaneva ◽  
Irena Mladenova ◽  
Galina Todorova ◽  
Dimitar Petkov
Keyword(s):  
Antibiotic Treatment ◽  
Chronic Wounds ◽  
Chronic Wound ◽  
Cross Sectional Study ◽  
P Value ◽  
Beta Lactam ◽  
Cross Sectional ◽  
Gram Negative ◽  
Beta Lactam Antibiotics ◽  
Wide Range

Background and aim. The problem of antibiotic resistance is worldwide and affects many types of pathogens. This phenomenon has been growing for decades and nowadays we are faced with a wide range of worrisome pathogens that are becoming resistant and many pathogens that may soon be untreatable. The aim of this study was to determine the resistance and antibiotic treatment in chronic wounds of vascular origin.Methods. We performed a cross sectional study on a sample of patients with chronic vascular wounds, hospitalized between October 2014 and August 2015, in the Clinic of Vascular Surgery in Trakia Hospital Stara Zagora. The statistical analysis of data was descriptive, considering the p value of ≤0.05, the threshold of statistical significance.Results. In the group of 110 patients, the significantly most frequent chronic wound (p<0.001) was peripheral arteriopathy (47.3%, CI95%: 38.19-56.54). Among 159 strains, 30% of patients having multiple etiology, the species most frequently isolated were Staphylococcus aureus, E.coli, Enterococcus faecalis, Pseudomonas aeruginosa and Proteus mirabilis with a significant predominance (p<0.05) of the Gram negative (55.1%). The spectrum of strains resistance included the Beta-lactams (36.4%, p<0.001), Macrolides (20%), Tetracyclines (9.1%), Aminoglycosides (8.2%) and Fluoroquinolones (4.5%).Conclusions. Gram negative microorganisms were the main isolates in patients with vascular chronic wound. Significantly predominant was the resistance to the beta-lactam antibiotics.

scholarly journals Evaluating the Effectiveness of Lumber Corset Wearing in Low Back Ache: A Rehabilitation Center Based Cross-sectional Study

2020 ◽  
Vol 9 (2) ◽  
pp. 90-98
Author(s):  
Ahmed I ◽  
Khan Md Jobair ◽  
Khan AR ◽  
Zaman S ◽  
Hawlader MDH
Keyword(s):  
Cross Sectional Study ◽  
Therapeutic Benefit ◽  
P Value ◽  
Low Back ◽  
Rehabilitation Center ◽  
Cross Sectional ◽  
Medical Practitioners ◽  
Wide Range ◽  
Back Ache ◽  
Poor Relationship

Patients are most commonly advised by medical practitioners even after remaining wide range of controversy regarding wearing of lumber corset in low backache (LBA). Therefore, this study aimed to determine the potential evidence of using lumber orthosis in LBA. The study adopted 50 participants (21 male and 29 female) ages ranging between 20 to 60 years as sample selecting randomly from September to December 2015. Outcome evaluated by calculating and presenting descriptive statistics at 0.05 p-value and x2 test with confidence intervals (95%), Odd Ratio (OR), and Relative Risk (RR). Age and sex were not statistically significant determinants (x2 1.172, p 0.279 and x2 0.593, p 0.441, respectively). Wearing orthosis and reduce pain in a journey found as protective (RR 0.79 and RR 0.94) also poor relationship discovered in considering OR (OR 0.242, 95% CI 0.021-2.780 and OR 0.857, 95% CI 0.164-4.467). Our data were unable to provide adequate proof that wearing lumber corset bring any clinical or therapeutic benefit in managing LBA to the patients.

scholarly journals Effect of Oral Nigella Sativa on Fasting Blood Glucose in Adults

2019 ◽  
Vol 4 (1) ◽  
Keyword(s):  
Blood Glucose ◽  
Nigella Sativa ◽  
Fasting Blood Glucose ◽  
Cross Sectional Study ◽  
P Value ◽  
Sectional Study ◽  
Cross Sectional ◽  
Wide Range ◽  
The World ◽  
Before And After

Introduction: Nigella Sativa is widely used traditional medicinal plant throughout the world as seeds and oil. It has been used to treat a wide range of disorders including Diabetes Mellitus (DM). Objective: Effect of oral Nigella Sativa on fasting blood glucose in non-diabetic individuals. Methods: A cross sectional study was conducted on 10 healthy non diabetic volunteers aged 20-35 years with normal fasting blood glucose (FBG). Subjects were given Nigella Sativa seeds orally (4gm) twice per day for 2 days. FBG was measured before and after Nigella Sativa supplementation by glucose oxidase methods using bio system A25. Results: The level of the fasting blood glucose was 99.4±3.1 mg/dl in the first day and deceased to 93.1±4.6 mg/dl after Nigella Sativa administration, which was statistically significant (p. value= 0.031). Conclusion: Nigella Sativa significantly reduced the level of blood glucose among non-diabetics adults. The mechanism of action of Nigella sativa needs to be investigated.

scholarly journals Chemical exposure in garage workers and related health risks on the biochemical levels: A comparative study in Harar town, eastern Ethiopia

2019 ◽  
Vol 7 ◽  
pp. 205031211984679
Author(s):  
Zerihun Ataro ◽  
Abraham Geremew ◽  
Fekadu Urgessa
Keyword(s):  
Clinical Chemistry ◽  
Biological Effects ◽  
Chemical Exposure ◽  
The United States ◽  
Cross Sectional Study ◽  
Control Group ◽  
P Value ◽  
Cross Sectional ◽  
Eastern Ethiopia ◽  
Wide Range

Objectives: Occupational exposure to chemicals causes a wide range of biological effects depending on the level and duration of exposure. The current study is intended to determine the differences in biochemical levels among garage workers compared with occupationally nonexposed participants in Harar town, eastern Ethiopia. Methods: A comparative cross-sectional study was conducted in Harar town, eastern Ethiopia. Thirty (30) garage workers were selected and compared with 30 age- and sex-matched control group of teachers and students. Demographic and occupational data were collected using a structured questionnaire by trained data collector. Biochemical levels were measured by automated clinical chemistry analyzer (Autolab 18, Boehringer-Mannheim Diagnostics, the United States). Data were analyzed using STATA Version 13. Results: All of the included garage workers were male. A statistically significant increase were found in alanine aminotransferase (35.60 ± 7.93 vs 19.17 ± 0.91 U/L; P value = 0.0440), aspartate aminotransferase (47.23 ± 4.89 vs 27.03 ± 1.13 U/L; P value = 0.0002), total protein (85.83 ± 1.16 vs 76.40 ± 0.86 g/l; P value < 0.0001), uric acid (7.34 ± 0.29 vs 5.19 ± 0.21 mg/dl; P value < 0.0001), glucose (85.13 ± 3.92 vs 75.60 ± 2.40 mg/dl; P value = 0.0425); total cholesterol (199.40 ± 13.11 vs 140.37 ± 3.81 mg/dl; P value = 0.0001) and triglyceride (143.40 ± 5.79 vs 110.60 ± 8.98 mg/dl; P value = 0.0033) in garage workers compared with control group. On the contrary, a statistically significant decrease were found in albumin (39.37 ± 1.78 vs 46.37 ± 0.56 g/l; P value = 0.0004) and urea (21.63 ± 1.04 vs 27.60 ± 1.69 mg/dl; P value = 0.0039) among garage workers compared with the control group. Conclusion: Our finding indicates that working in the garage changes most of the biochemical levels. Therefore, appropriate and effective safety measures need to be implemented to prevent possible chemical exposure during routine work.

scholarly journals Healing of Chronic Wounds with Platelet-Derived Growth Factors from Single Donor Platelet-Rich Plasma following One Freeze-Thaw Cycle. A Cross-Sectional Study

2021 ◽  
Vol 10 (24) ◽  
pp. 5762
Author(s):  
Vidán-Estévez Vidán-Estévez ◽  
Sánchez-Herráez Sánchez-Herráez ◽  
Escalante-Barrigón Escalante-Barrigón ◽  
Seco-Calvo Seco-Calvo
Keyword(s):  
Chronic Wounds ◽  
Platelet Rich Plasma ◽  
Cross Sectional Study ◽  
P Value ◽  
Sectional Study ◽  
Cross Sectional ◽  
Freeze Thaw ◽  
Single Donor ◽  
Thaw Cycle ◽  
Freeze Thaw Cycle

Chronic non-healing wounds (CNHWs) may be associated with trauma or idiopathic in nature and are difficult to treat. Our objective was to assess the use of platelet-derived growth factor (PDGF) from single-donor platelets (al-PRP), using one freeze-thaw cycle, for treating CNHWs. We conducted a cross-sectional study. A total of 23 CNHWs being treated with al-PRP. The al-PRP treatment can be considered successful in well over half (n = 13, 56.5%) of the wounds. We found that all the wounds treated for up to 7 weeks showed partial or complete healing, while those treated for between 8 and 12 weeks did not show healing, healing again being successful in cases in which treatment was extended to more than 13 weeks (85.7%). Using chi-square tests, this relationship was found to be highly significant (p < 0.001, chi2 = 19.51; p value = 0.00006). Notably, Cramer’s V coefficient was very high (0.921), indicating that the effect size of PRP treatment duration on healing is very large (84.8%). We could suggest that the use of al-PRP in the healing of CNHWs is a promising approach. Further studies with larger sample sizes and long follow-ups are needed to obtain multivariate models to explain which factors favour the healing of ulcers treated with PRP

scholarly journals Functional outcomes of ACL reconstruction using hamstring auto graft.

2019 ◽  
Vol 26 (11) ◽  
pp. 1965-1970
Author(s):  
Zeeshan Ali Khan ◽  
Benash Altaf ◽  
Samia Javed ◽  
Sadaf Altaf Sadaf Altaf ◽  
Shireen Jawed
Keyword(s):  
Acl Reconstruction ◽  
Rating Scale ◽  
Cruciate Ligament ◽  
Demographic Data ◽  
Cross Sectional Study ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Wide Range ◽  
Effect Of Age

Objectives: The knee joint is made of two cruciate ligaments. One is anterior cruciate ligament (ACL) which is weaker when it comes to comparison with the other cruciate ligament known as posterior cruciate ligament (PCL). ACL tears are most common and frequently neglected. ACL tear is affecting 70% of the population and this high incidence reflects the significance of the problem. Reason of restoration of a torn ACL is to provide knee stability, knee motion in a safe wide range and to prevent osetoarthritis OA. The gold standard for ACL auto-graft reconstruction is bone patella-tendon bone (BTB) which is still questioned by many researchers as this technique followed subjects suffered from knee pain. So aim is to use and to access outcomes of hamstring auto-graft for reconstruction ACL by using Tegner’s score. Study Design: Cross sectional study. Setting: Private based hospital, Faisalabad. Period: January 2017 to January 2019. Material and Methods: It was comprised of in comprised of 97 subjects recruited on the base of positive Tegners score. Demographic data including age was presented as mean and standard deviation. Data was stratified for the variables i.e. age, gender, duration of disease and pre-operative Tegner activity rating scale to address the effect modifiers. Post-stratification Chi-square test is applied to check the significance with P-value less than 0.05 as significant. Regression was applied to check the effect of age on Tegner’s scor. Results: This study comprised of 97 subjects (81 male, 16  females83.5.5% and 16.5% respectively from private setup based hospital with mean age of 31±11.1.Our study showed 96.9% subjects with improved Tegner’s scale after ACL reconstruction following hamstring autograph technique. Regression was also applied to check the effect of age on Tegner’s score which was found to be significant (p value0.00*). Conclusion: Hamstring technique showed good outcomes which can be used to reconstruct ACL for better quality lifestyle.

Brief Overview and Experience of Visual Evoked Potential of First 67 cases at Referral Neuroscience Hospital in Bangladesh

2020 ◽  
Vol 6 (2) ◽  
pp. 74-77
Author(s):  
Mohammad Enayet Hussain ◽  
Bithi Debnath ◽  
AFM Al Masum Khan ◽  
Md Ferdous Mian ◽  
Md Nahidul Islam ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Optic Neuritis ◽  
Clinical Diagnosis ◽  
Optic Neuropathy ◽  
Cross Sectional Study ◽  
P Value ◽  
Pattern Reversal ◽  
Cross Sectional ◽  
The Mean ◽  
Visual Evoked

Background: The visual evoked potentials (VEP) is a valuable tool to document occult lesions of the central visual channels especially within the optic nerve. Objectives: The purpose of the present study was to observe the findings of first few cases of VEP done in the neurophysiology department of the National Institute of Neurosciences (NINS), Dhaka, Bangladesh. Methodology: This cross-sectional study was conducted in the Department of Neurophysiology at the National Institute of Neurosciences and Hospital, Dhaka, Bangladesh from September 2017 to March 2020. All patients referred to the Neurophysiology Department of NINS for VEP were included. Pattern reversal VEPs were done using standard protocol set by International Federation of Clinical Neurophysiology (IFCN). Results: The mean age of the study population was 30.70 (±12.11) years (6-68 years) with 31 (46.3%) male and 36 (53.7%) female patients. The mean duration of illness was 8.71 (±1.78) months (3 days- 120 months). Most common presenting symptom was blurring of vision (37.3%) and dimness of vision (32.8%). Patterned VEP revealed mixed type (both demyelinating and axonal) of abnormality in most cases [29(43.35)]. The most common clinical diagnosis was multiple sclerosis (29.85%) and optic neuropathy (26.87%). In the clinically suspected cases of multiple sclerosis, optic neuropathy and optic neuritis most of the cases of VEP were abnormal and the p value is 0.04 in optic neuropathy and optic neuritis. Conclusion: The commonest presentation of the patients in this series were blurring of vision and dimness of vision. The most common clinical diagnosis for which VEP was asked for, was optic neuritis and multiple sclerosis. Most abnormalities were of mixed pattern (demyelinating and axonal). Journal of National Institute of Neurosciences Bangladesh, 2020;6(2): 74-77

THE RELATION OF COPPING STRATEGY BY LOOKING SOCIAL SUPPORT WITH STRESS LEVEL OF BREAST CANCER PATIENT WHO GONE TROUGH CHEMOTHERAPY

2018 ◽  
Vol 1 (1) ◽  
pp. 51-54
Author(s):  
Sri Burhani Putri
Keyword(s):  
Breast Cancer ◽  
Social Support ◽  
Cancer Patient ◽  
Breast Cancer Patient ◽  
Cross Sectional Study ◽  
P Value ◽  
Spiritual Support ◽  
Cross Sectional ◽  
Breast Cancer Chemotherapy ◽  
Patient Stress

Breast cancer is one of the most common illness that killed woman. One of the therapy to cure breast cancer is chemotherapy. Chemotherapy has side effect either physical and psychology, that caused people who’s in chemo therapy, prone to stress. Stress effected by many factors, such as characteristic and chopping strategy that patient has been using. The aim of this research is to get a perspective about the relation of characteristic and chopping strategy with breast cancer patient stress, whose in chemo therapy. This research using cross sectional study and taking sample by using accidental sampling method. The data analyzed by using bavariat and multivariat with variable result shows that breast cancer patient stress who has chemo therapy realted to age characteristic (p value = 0.00) the time since they diagnosed with cancer (pvalue = 0.03), how long they have chemo therapy (pvalue = 0.00) and chopping strategyby looking social support (pvalue = 0.00) looking for spiritual (pvalue = 0.00) with dominan variable which related to stress is chopping strategy to looking spiritual support (coeffecients B = -1.139).   Key words : Breast cancer, chemotherapy, stress  

Faktor Risiko Kejadian Penyakit Kulit Pada Pekerja Pengangkut Sampah Di Kota Jambi

2017 ◽  
Vol 6 (2) ◽  
pp. 129
Author(s):  
Entia Nopa ◽  
Ranissa Dwi Imansari ◽  
Irwandi Rachman
Keyword(s):  
Cross Sectional Study ◽  
Personal Hygiene ◽  
P Value ◽  
Sectional Study ◽  
Chi Square ◽  
Cross Sectional

Faktor Risiko Kejadian Penyakit Kulit Pada Pekerja Pengangkut Sampah Di Kota Jambi 1Entianopa, 2Ranissa Dwi Imansari, 3Irwandi Rachman       123Program Studi Kesehatan Masyarakat STIKES Harapan Ibu, Jambi   Abstrak Latar Belakang: Kulit merupakan organ terbesar pada tubuh manusia yang membungkus otot-otot dan organ-organ dalam serta merupakan jalinan jaringan pembuluh darah, saraf, dan kelenjar yang tidak berujung, semuanya memiliki potensi untuk terserang penyakit yang salah satunya adalah penyakit kulit. Penyakit kulit merupakan salah satu gangguan kesehatan yang sering dialami oleh pekerja pengangkut sampah. Berdasarkan komposisi sampah yang diangkut serta waktu paparan kerja. Tujuan penelitian ini untuk mengetahui hubungan antara masa kerja, pemakaian Alat Pelindung Diri (APD), dan personal hygiene dengan kejadian penyakit kulit pada pekerja pengangkut sampah di Kota Jambi. Metode: Penelitian ini merupakan penelitian kuantitatif dengan desain penelitian cross sectional study. Sampel penelitian yaitu sebanyak 62 pekerja pengangkut sampah yang berada di Kantor Pekerjaan Umum dan Penata Ruang, yang mana seluruh populasi dijadikan sampel. Data dikumpulkan berdasarkan pemeriksaan kesehatan oleh dokter dan dengan kuesioner, kemudian dianalisa menggunakan uji statistik chi-square. Hasil: Hasil menunjukan bahwa pekerja yang mengalami penyakit kulit sebanyak 35 pekerja (56,5%). Berdasarkan hasil analisis chi-square didapatkan bahwa ada hubungan yang bermakna antara masa kerja dengan kejadian penyakit kulit pada pekerja pengangkut sampah dimana nilai (p-value= 0,006), Pemakaian Alat Pelindung Diri (APD) nilai (p-value= 0,008), personal hygiene nilai (p-value= 0,008). Kesimpulan: Untuk meminimalisir risiko terjadinya penyakit kulit pada pekerja pengangkut sampah disarankan perlunya disusun standar operasional prosedur yang aman, penyediaan sarana sanitasi agar dapat mengurangi resiko terkena penyakit kulit. Pentingnya pemakaian APD dan perilaku hidup bersih dan sehat selama bekerja, serta diharapkan pekerja menggunakan APD pada saat bekerja dan lebih memperhatikan personal hygiene.   Kata kunci      : Masa Kerja, APD, Personal Hygiene

Spectrum of Pathological Lesions in Uterine Specimens with Focus on Gestational Trophoblastic Disease in Karachi

2020 ◽  
Keyword(s):  
Hydatidiform Mole ◽  
Endometrial Stromal Sarcoma ◽  
Gestational Trophoblastic Disease ◽  
Cross Sectional Study ◽  
Reproductive Age ◽  
P Value ◽  
Cross Sectional ◽  
Endometrial Polyps ◽  
Trophoblastic Disease ◽  
Proliferative Endometrium

Background: The most common benign pathological lesion in women of reproductive age is uterine leiomyoma. Gestational trophoblastic disease includes tumors and tumor like lesions originating from trophoblastic tissue. The aim of this study was to find the spectrum of molar pregnancy and uterine pathologies focusing on gestational trophoblastic disease as no study has been done in the past few years. Methods: Endometrial and uterine specimens of patients (n=436) between the ages of 15-65 years were collected from a private hospital in Karachi from December 2018 to December 2019. This cross-sectional study was carried out by pathological diagnosis of patients’ samples under light microscopy using hematoxylin and eosin staining. Stratification was done about age and nature of specimen to control the effect modifiers. The post stratification Chi square test was applied and p value <0.05 was considered significant. Results: Mean age of the patients was 36.1 years ±7.8. Total 436 uterine biopsies included 260(59.6%) hysterectomies, 56(12.8%) endometrial curetting’s, 117(26.8%) evacuation specimens and 3(0.7%) polypectomies. Common pathologies included 124(28.4%) leiomyomas, 61(14%) proliferative endometrium, 52(11.9%) adenomyosis and 32(7.3%) endometrial polyps. Gestational trophoblastic disease was seen in 9(2.06%). Seven (87.5%) were partial hydatidiform moles, one (12.5%) exaggerated placental site reaction and one choriocarcinoma. Mole was common between 26-30 years with mean age of 27.2 years and prevalence was 6/100 abortions. Conclusion: Leiomyoma was the commonest (28.4%) uterine pathology followed by proliferative endometrium (14.5%). However, endometrial stromal sarcoma and endometriosis were found 0.2% each. High prevalence of mole was seen in this study. Partial mole was most common and choriocarcinoma was least common. Keywords: Hydatidiform Mole; Pathology; Prevalence.

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