scholarly journals Determinação de valores próprios de referência para vitamina D, hormônio paratireoideo e cálcio em um laboratório de análises clínicas

2018 ◽  
Vol 28 (4) ◽  
pp. 28462 ◽  
Author(s):  
Adriana Dalpicolli Rodrigues ◽  
Estefânia Weirich ◽  
Eunice Zanandréa Duarte
Keyword(s):  
Vitamin D ◽  
Direct Method ◽  
Package Insert ◽  
Cross Sectional Study ◽  
Reference Intervals ◽  
Lower Range ◽  
Cross Sectional ◽  
Laboratory Workers ◽  
The Mean

AIMS: To determine the proper reference intervals for vitamin D, parathyroid hormone (PTH) and calcium in a clinical laboratory.METHODS: A retrospective cross-sectional study was carried out at the units of Alfa Ltda. Laboratory, located in Caxias do Sul, in the mountain region of Rio Grande do Sul. The sample included self-declared healthy clients and laboratory workers. The study was based on two research methods (direct and indirect) proposed by the Clinical & Laboratory Standards Institute for the establishment of proper reference intervals for a specific laboratory. The direct method (DM) involved questionnaire application, collection and analysis of blood samples and the indirect method (IM) consisted of database analysis.RESULTS: Results of 241 individuals were evaluated in the DM, of which 120 were female. The mean age of participants was 33.8±10.6 years. IM resulted in 5,485 values for vitamin D, 191 for PTH, and 856 for calcium. The mean age of the individuals was 45.0±15.6 years, 49.0±15.3 years and 48.87±15.41 years, respectively. The proper reference intervals obtained by the DM were statistically equal to those of the IM for the three dosages. When comparing the reference intervals obtained with those available in the manufacturer report, vitamin D resulted in a lower range of normality (report: >30 ng/mL; MD: 10-47 ng/mL; MI: 11-46 ng/mL), PTH in a higher range (report: 15-68.3 ng/mL; MD: 19.2-81.6 ng/mL; MI: 26.1-94.3 ng/mL), and calcium presented very close values (report: 8.3-10.6 ng/mL; MD: 8.3-10.2 ng/mL; MI: 8.2-10.1 ng/mL). There was a statistical difference between the reference intervals established for vitamin D and calcium between genders.CONCLUSIONS: Both MD and MI were efficient for the determination of proper reference intervals. The reference intervals established in the study, specifically for vitamin D and PTH, were different from those suggested in the manufacturer's package insert, which reinforces the recommendation of establishing proper reference intervals for each laboratory.

scholarly journals KNOWLEDGE AND PRACTICES REGARDING VITAMIN D DEFICIENCY AMONG WOMEN ATTENDING IMAM HUSSEIN MEDICAL CITY IN KARBALA 2018

2019 ◽  
pp. 39-43
Author(s):  
SARAH JAFAR AL-GHRAIBAWI ◽  
SAAD IBRAHIM AL-GHABBAN ◽  
RIYADH DHEYHOOD AL-ZUBAIDY
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Public Awareness ◽  
Sun Exposure ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Significant Difference ◽  
Medical City ◽  
The Mean ◽  
Socio Demographic Factors

Objective: Vitamin D deficiency is a global health problem. It is significantly associated with skeletal and non-skeletal problems. Prevention can be maintained mainly by effective sun exposure or supplementation and to lesser extent by dietary intake. To determine the magnitude of knowledge and practice of women towards vitamin D deficiency. Methods: A cross-sectional study, purposive sample of 442 women were approached who attended consultants’ clinics of Imam Hussein Medical City in Karbala. Data collection done between March 2 and June 30, 2018 through direct interviews using a special questionnaire prepared for the purpose of the study. Results: Less than half (45.2%) of the women had heard about vitamin D; their source of information was from relatives and friends then from health care provider. The mean score for the participants’ knowledge about VDD was 4.25 out of 9.0 (47%). It has a significant association with higher educational levels and urban residence. There is no significant difference regarding age, marital status or occupation. The mean score for the participants’ practice about vitamin D deficiency was 2.53 out of 5 (50.71%). There is no influence of practice score by socio-demographic factors. Conclusion: Overall knowledge towards vitamin D deficiency was suboptimal. Improving practices towards VD is directly related to increase knowledge about it that indicates the need to increase public awareness about the problem, encourage appropriate way of sun exposure, consumption of vitamin D rich food and taking supplementation when sun exposure is difficult.

scholarly journals Thyroid Function and 25 (OH) Vitamin D Level among Sudanese Women in Early Pregnancy

2018 ◽  
Vol 6 (3) ◽  
pp. 488-492
Author(s):  
Imad R. Musa ◽  
Duria A. Rayis ◽  
Mohmamed A. Ahmed ◽  
Ammar H. Khamis ◽  
Abubakr M. Nasr ◽  
...  
Keyword(s):  
Vitamin D ◽  
Thyroid Function ◽  
Early Pregnancy ◽  
Cross Sectional Study ◽  
The Body ◽  
Sectional Study ◽  
Cross Sectional ◽  
Vitamin D Levels ◽  
The Mean ◽  
25 Oh Vitamin D

AIM: A cross-sectional study was conducted at Saad Abualila Hospital (Khartoum, Sudan) to evaluate the vitamin D levels and thyroid function among pregnant Sudanese women (132) in early pregnancy.METHODS: A cross-sectional study was conducted at Saad Abualila hospital (Khartoum, Sudan) during the period from March to July 2015. Women who were in early pregnancy with a singleton pregnancy were approached to participate in the study after signing informed consent. A sample size of 132 participants was calculated guided by the normal interval of thyroid function in Sudanese women in the first trimester and not the level of 25(OH) vitamin D. The 25 - hydroxyvitamin D (25 (OH) vitamins levels were measured using an electrochemiluminescence immunoassay on an Elecsys 2010 Analyzer (Roche Diagnostics, Mannheim, Germany).RESULTS: The mean (SD) of age, gravidity and gestational age was 27.6 (5.5) years, 2.2 (1.6) and 10.4 (2.2) weeks, respectively. The mean (SD) of the body mass index (BMI) and haemoglobin was 27.1 (5.2) kg/m2 and 10.8 (1.1) g/dl, respectively. Median (interquartile) values of TSH, FT3, and FT4 were 1.164 IU/ml (0.079 -2.177 IU/ml), 4.639 nmol/l (3.843 - 6.562 nmol/l), and 16.86 pmol/l (13.02 - 31.48 pmol/l), respectively. There was no significant correlation between vitamin D levels and TSH, FT3 and FT4CONCLUSION: There is no correlation between 25 (OH) vitamin D levels and thyroid function during early pregnancy among Sudanese pregnant women, despite prevalent vitamin D deficiency among these women.

scholarly journals DETERMINATION OF THE COMBINED WIDTH OF MAXILLARY ANTERIOR TEETH USING INNERCANTHAL DISTANCE WITH RESPECT TO AGE GENDER AND ETHINICITY

2021 ◽  
Vol 71 (Suppl-1) ◽  
pp. S164-69
Author(s):  
Naseer Ahmed ◽  
Maria Shakoor Abbasi ◽  
Danish Azeem Khan ◽  
Shiza Khalid ◽  
Warda Jawed ◽  
...  
Keyword(s):  
Cross Sectional Study ◽  
Gender Disparities ◽  
Sectional Study ◽  
Weak Correlation ◽  
Cross Sectional ◽  
Anterior Teeth ◽  
Significant Difference ◽  
The Mean ◽  
The Relationship

Objective: To evaluate the relationship between inner canthal distance and maxillary anterior teeth width withrespect to age, gender and ethnicity. Study Design: Cross sectional study. Place and Duration of Study: Altamash Institute of Dental Medicine, Karachi, from Aug 2019 to Jan 2020. Methodology: One hundred participants from both genders with full permanent dentition, no interdental space or pathology and facial symmetry were included in this study. The measurements were carried out with digital Vernier caliper. SPSS-25 was used for statistical analysis. Results: The mean ± SD of inner canthal distance and width of maxillary anterior teeth were 2.99cm ± 0.46and 3.82cm ± 0.35 respectively. A significant difference was found between gender (p=0.037) and inner canthaldistance. The maxillary anterior teeth width and inner canthal distance varies amongst different ethnicities(p=0.01). The inner canthal distance does not vary with advancing age (p=0.87) whereas width of maxillaryanterior teeth varies (p=0.04). A weak correlation value of 0.47 was found between inner canthal distance andmaxillary anterior teeth width. Conclusion: This research suggests that there is a weak relationship between inner canthal distance and maxillary anterior teeth width. Therefore, a multiplication ratio of 1.27 is advised to get combined mesiodistal width of maxillary anterior teeth. Additionally, the value of both differs in various local ethnicities. Inner canthal distance does not vary with age though has significant gender disparities while maxillary anterior teeth width remains constant.

scholarly journals Establishment of a new relationship between posed smile width and lower facial height: A cross-sectional study

2015 ◽  
Vol 09 (03) ◽  
pp. 394-399 ◽  
Author(s):  
Aby Abraham ◽  
Jinu George ◽  
Elbe Peter ◽  
Koshi Philip ◽  
Rajesh Chankramath ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Facial Height ◽  
The Face ◽  
Facial Proportions ◽  
Males And Females ◽  
The Mean ◽  
The Difference

ABSTRACT Objective: The present study is intended to add a new parameter that would be useful in orthodontic clinical evaluation, treatment planning, and determination of vertical dimension (at occlusion). Materials and Methods: Standardized videographic recording of 79 subjects during posed smile was captured. Each video was then cut into 30 photos using the free studio software. The widest commissure-to-commissure posed smile frame (posed smile width [SW]) was selected as one of 10 or more frames showing an identical smile. Lower third of the face is measured from subnasale to soft tissue menton using a digital vernier caliper. Two values were then compared. Ratio between lower facial height and posed SW was calculated. Results: The co-relation between smiling width and lower facial height was found to be statistically significant (P < 0.01). The ratio of lower facial height and smiling width was calculated as 1.0016 with a standard deviation (SD) = 0.04 in males and 1.0301 with an SD = 0.07 in females. The difference between the mean lower facial height in males and females was statistically significant with a t = 10.231 and P = 0.000. The difference between the mean smiling width in males and females was also statistically significant with a t = 5.653 and P = 0.000. Conclusion: In class I subjects with pleasing appearance, normal facial proportions, normal overjet and overbite, and average Frankfort mandibular angle, the lower facial height (subnasale to soft tissue menton) is equal to posed SW.

Association between vitamin D level and prognostic factors among patients infected with SARS-CoV-2

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Mehrdad Haghighi ◽  
Seyed Shayan Ebadi ◽  
Hussein Soleimantabar ◽  
Atefe Shadkam ◽  
Seyed Alireza Ebadi ◽  
...  
Keyword(s):  
Vitamin D ◽  
Prognostic Factors ◽  
Medical Records ◽  
Lymphocyte Count ◽  
Cross Sectional Study ◽  
C Reactive Protein ◽  
Cross Sectional ◽  
Reactive Protein ◽  
The Mean ◽  
D Dimer

Abstract Objectives The present study aimed to evaluate the presence of any relationship between vitamin D and prognostic factors among patients infected with SARS-CoV-2. Methods This retrospective cross-sectional study was conducted among patients admitted from March to August 2020 in a referral hospital, Tehran, Iran. All patients aged 18–65 who had not any comorbidity participated in the study. The diagnosis of COVID-19 was established using the rRT-PCR test for SARS-CoV-2 detection. Then the incidence of lung involvement and biochemical markers including vitamin D level, c-reactive protein, D-dimer, lymphocyte count, platelet count, white blood cell count, and lactic acid dehydrogenase, were extracted through medical records. Results Altogether, 84 patients met our study criteria, and the information of 68 (80.9%) participants were collected. Among all 68 patients, 45 (66.2%) were male. The mean (SD) age of all participants was 52.4 (10.4) years old. Among 24 (35.2%) clients who died due to SARS-CoV-2, 20 (83.3%) patients were male (p=0.02). The mean (SD) of vitamin D level was 24.1 (13.6) ng/dL. No association between vitamin D level and prognostic factors, including CRP, lymphocyte count, D-dimer, LDH, and HRCT scan score, was observed. Also, the vitamin D level of the dead patients was not significantly different from that of the treated patients. Conclusions Our findings indicated no significant relationship between vitamin D level and prognostic factors or outcomes of patients infected with SARS-CoV-2.

scholarly journals Serum 25(OH)D Level and Parathyroid Hormone in Chinese Adult Population: A Cross-Sectional Study in Guiyang Urban Community from Southeast of China

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Zhang Qiao ◽  
Shi Li-xing ◽  
Peng Nian-chun ◽  
Xu Shu-jing ◽  
Zhang Miao ◽  
...  
Keyword(s):  
Vitamin D ◽  
Parathyroid Hormone ◽  
Secondary Hyperparathyroidism ◽  
Adult Population ◽  
Cross Sectional Study ◽  
Vitamin D Insufficiency ◽  
Cluster Sampling ◽  
Cross Sectional ◽  
The Mean ◽  
Serum Pth

Objective. To evaluate vitamin D status and serum parathyroid hormone (IPTH) of healthy adults living in Guiyang.Design and Participants. We conducted a cross-sectional evaluation in the General Community in Guiyang by cluster sampling method. The data was a part of 1510 participants (634 men, 876 women) aged 20–79 years median 45.2 years from November 2009 to February 2010 in Guiyang Health Measures Survey.Measurements. Aradioimmunoassay was used to measure the level of 25-hydroxyvitamin D [25(OH)D] and intact parathyroid hormone (iPTH).Results.The mean serum 25(OH)D level was (20.4 ± 9.0) ng/mL and the highest level among participants aged 40–59 years (22.8 ng/mL). The mean serum PTH level was (32.1 ± 13.7) pg/mL and the lowest level among participants aged 40–50 years (30.8 ng/mL). Serum 25(OH)D was below 50 nmol/liter in 52.3%, below 75 nmol/liter in 84.6%, and above 75 nmol/liter in 15.4% of the respondents. Secondary hyperparathyroidism was 5.4% (5.4% among men and 4.6% among women). The prevalence of secondary hyperparathyroidism increased (5.8%, 6.5%, and 7.1%, resp.) with decreasing serum 25(OH)D levels among subjects who were 30 to 20, 19.9 to 10, and <10 ng/mL, respectively. Serum 25(OH)D was inversely associated with serum PTH.Conclusions. Vitamin D insufficiency and its complication of secondary hyperparathyroidism are common.

Vitamin D Status in Irish Children and Adolescents

2014 ◽  
Vol 53 (14) ◽  
pp. 1345-1351 ◽  
Author(s):  
Aoife Carroll ◽  
Chike Onwuneme ◽  
Malachi J. McKenna ◽  
Philip D. Mayne ◽  
Eleanor J. Molloy ◽  
...  
Keyword(s):  
Vitamin D ◽  
Cross Sectional Study ◽  
Healthy Children ◽  
Vitamin D Status ◽  
Formula Milk ◽  
Cross Sectional ◽  
Hydroxyvitamin D ◽  
25 Hydroxyvitamin D ◽  
The Mean ◽  
Vitamin D Supplements

Background. Vitamin D has important skeletal and extraskeletal roles but those living at northerly latitudes are at risk of suboptimal levels because of reduced sunlight exposure. Aim. To describe the vitamin D status of Irish children and identify factors predictive of vitamin D status. Methods. A prospective cross sectional study was undertaken over a 12 month period. Two hundred and fifty two healthy children attending for minor medical or surgical procedures were recruited. All had 25-hydroxyvitamin D (25OHD), parathyroid hormone and bone profiles measured. Results. The mean (standard deviation) for 25OHD was 51(25) nmol/L (20.4 (10) ng/mL). Forty-five percent had levels >50 nmol/L (20 ng/mL). The following variables were significantly associated with 25OHD levels >50 nmol/L (20 ng/mL): sample drawn in April-September, use of vitamin D supplements, consumption of formula milk, and non-African ethnicity. Conclusion. More than half of the children in this study had 25OHD levels less than 50 nmol/L (20 ng/mL). Vitamin D status was significantly improved by augmented oral vitamin D intake.

scholarly journals Vitamin D epimers are associated with circulating haemoglobin levels independently of C-reactive protein

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
La-or Chailurkit ◽  
Piyamitr Sritara ◽  
Prin Vathesatogkit ◽  
Sukit Yamwong ◽  
Nisakron Thongmung ◽  
...  
Keyword(s):  
Vitamin D ◽  
Venous Blood ◽  
High Sensitivity ◽  
Cross Sectional Study ◽  
Total Serum ◽  
C Reactive Protein ◽  
Cross Sectional ◽  
Reactive Protein ◽  
Long Term Follow Up

AbstractVitamin D deficiency has been shown to be associated with anaemia. Circulating 25(OH)D consists of both epimeric and nonepimeric forms. However, the relative roles of epimeric and nonepimeric vitamin D in regulating anaemia and haemoglobin levels remain unknown. Therefore, in this study, we examined the effect of vitamin D, including its epimers, on haemoglobin levels, independently of its effect on circulating high-sensitivity C-reactive protein (hsCRP). This was a cross-sectional study of 1655 subjects from a long-term follow-up cohort at the Electricity Generating Authority of Thailand. Venous blood sample were collected for determination of vitamin D [25(OH)D2, 25(OH)D3, 3′-epi-25(OH)D2, and 3′-epi-25(OH)D3], haemoglobin, and hsCRP levels. Data are presented as mean ± standard deviation. Age, sex, and body mass index (BMI) were significantly associated with circulating haemoglobin levels, while no association was found between total serum 25(OH)D and haemoglobin levels. However, when total 25(OH)D was separated into 3′-epimeric and non-3′-epimeric forms, 3′-epi-25(OH)D was significantly associated with haemoglobin levels, independently of age, sex, and BMI (P < 0.01). No association was found between non-3′-epi-25(OH)D and haemoglobin. When hsCRP was added to the model, the effect 3′-epi-25(OH)D on haemoglobin levels remained significant (P < 0.01). In conclusion, vitamin D epimers are associated with circulating haemoglobin levels, which supports the role of vitamin D in red blood cell and iron physiology.

scholarly journals Awareness Regarding Vitamin D Amongst The Medical And Non-medical Students Of Karachi

2019 ◽  
Vol 09 (03) ◽  
pp. 197-201
Author(s):  
Asma Dahar ◽  
Tahira Assad ◽  
Hafiza Touseef Sayyar
Keyword(s):  
Vitamin D ◽  
Medical Students ◽  
Cross Sectional Study ◽  
Dental Students ◽  
Sectional Study ◽  
Cross Sectional ◽  
The Mean ◽  
Graduate Trainees ◽  
Male Subjects ◽  
Medical And Dental Students

Objective: To assess the awareness regarding Vitamin D amongst medical and non-medical students. Study Design and Setting: A cross-sectional study was conducted during the period December 2016-June 2017 on a sample size of 388 subjects. Methodology: Undergraduate medical and dental students that are in their 3rd or 4th year, house officers, post graduate trainees and graduate medical students were included in the study. Undergraduate and graduate students from non-medical institutes were also included. The participants were assessed on the basis of a questionnaire which contained 15 closed ended questions. Results: The age of participants in this research varied from 21 to 35 years with the mean age of 24. Male subjects were 25 % but the females were predominant in this study, calculating 75%. Medical subjects were 70.4% (n= 273) and Nonmedical subjects were 29.6% (n= 115). Undergraduates were 79.4% (n=308) and Graduates were 20.6% (n=80). An overall of 75% of the medical subjects have satisfactory knowledge as compared to 25% of the non-medical subjects. Conclusion: There is a lack of awareness regarding vitamin D among non-medical students. Awareness of vitamin among medical students was also not up to the mark

scholarly journals Role of Common Addictive Habits on Hypovitaminosis D among Bangladeshi People

2019 ◽  
Vol 31 (2) ◽  
pp. 89-92
Author(s):  
AHM Habibur Rahman ◽  
Md Emdadul Haque ◽  
Lubna Naznin ◽  
Nasir Uddin Ahmed
Keyword(s):  
Vitamin D ◽  
Armed Forces ◽  
Hypovitaminosis D ◽  
Cross Sectional Study ◽  
Nutritional Disorder ◽  
Cross Sectional ◽  
Effective Measure ◽  
The Mean ◽  
Medicine Today

Introduction: Hypovitaminosis D is a silent but very devastating health issue throughout the world. Some common addictive habits in our country play important role on the issue. The objective of this study was to determine the role of common addictive habits on hypovitaminosis D among the clients attending specialized hospitals. Materials and Methods: This cross-sectional study was conducted among 264 respondents attended Armed Forces Institute of Pathology (AFIP), Dhaka Cantonment for estimation of 25(OH) D within the period of July 2017 to June 2018. Data were collected by face-to-face interview, reviewing with Vitamin D level of the participants from laboratory with the help of a semi-structured questionnaire and checklist respectively. Data were checked, and analyzed with the help of SPSS version 23. Results: Among the respondents, majority (68.56%) were female. The mean ±SD age of the respondents was 48.23 ± 14.05 years. The mean± SD level of 25(OH)D was 50.01± 29.93 nmol/L. Among the males, it was 50.86±28.61 nmo/L and 49.60±26.19 nmol/L among the female. The proportion hypovitaminosis D was 84.84% and a mare difference was found among male and female respondents (84.5% and 85.5% respectively. Smokers (43.88±13.01 nmol/L) were found with lower level of vitamin D than non-smokers (50.88±28.08 nmol/L) (p<0.05).The respondents having habit of chewing betel nut showed lowerlevel of 25 (OH) D than those does not practice that (51.63±18.07 Vs 46.12±13.01 mmol/L). Conclusion: The proportion of hypovitaminosis D was too high. Effective measure to be taken at all level to overcome the nutritional disorder. Medicine Today 2019 Vol.31(2): 89-92

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