scholarly journals A vesetranszplantációval kapcsolatos betegedukációs program tapasztalatai a kelet-magyarországi régióban

2021 ◽  
Vol 162 (26) ◽  
pp. 1012-1021
Author(s):  
Anita Barth ◽  
Gergő József Szőllősi ◽  
Balázs Nemes
Keyword(s):  
Kidney Transplantation ◽  
Data Collection ◽  
Knowledge Score ◽  
Adequate Health Literacy ◽  
Renal Replacement Therapies ◽  
Medical Evaluation ◽  
Health Literacy Level ◽  
Modifiable Factor ◽  
Level Of Knowledge

Összefoglaló. Bevezetés: A tudás mint potenciálisan módosítható faktor a megfelelő döntéshozatal előfeltétele. Célkitűzés: Kutatásunk során a krónikus vesebetegek körében vizsgáltuk az egyes vesepótló kezelési módokkal kapcsolatos ismereteket, elemeztük a tudást befolyásoló tényezőket, annak érdekében, hogy feltérképezzük a betegismeretek e területen megfigyelhető hiányosságait. Egyúttal tájékoztatást és ismeretterjesztést adtunk a vesetranszplantációval kapcsolatosan. Módszer: A betegek ismereteit befolyásoló tényezőket tíz magyarázó változóra korrigált többváltozós lineáris regresszióval értékeltük, melynél a függő változó a tudáspontszám volt. Követéses vizsgálatunk első adatfelvétele során az Eurotransplant-várólistán szereplő, vesetranszplantáció irányában kivizsgálás alatt álló, valamint a veseátültetést elutasító, 18 és 75 év közötti betegeket kerestük fel. Az első körös (alaptudásszintet rögzítő) adatfelvétel összesen 254, az ismeretátadás utáni második pedig 115 vesebeteg bevonásával valósult meg. Eredmények: Eredményeink alapján elmondható, hogy a felsőfokú (β = 1,502, p<0,001) és a középfokú (β = 2,346, p<0,001) iskolai végzettséggel rendelkező betegek egyaránt magasabb tudáspontszámot értek el az alacsonyabb iskolai végzettséggel rendelkezőkhöz képest. A korábban veseátültetésen már átesett betegek 2 ponttal magasabb pontszámot értek el a veseátültetésben még nem részesültekhez viszonyítva (β = 2,024, p<0,001). Szignifikánsan magasabb pontszámot értek el azok a betegek is, akik megfelelő egészségműveltségi szinttel rendelkeztek (β = 1,344, p<0,001). Eredményeink bizonyítják programunk hatékonyságát, mert a részt vevő vesebetegek szignifikánsan magasabb pontszámot értek el a tudásszintfelmérő teszten, több hónappal a betegedukációt követően is (p<0,001). Következtetés: Az általunk azonosított hiányosságok segíthetnek az egészségügyi szakemberek számára abban, hogy melyek azok a területek, amelyekre a betegoktatási és önmegvalósító programok során hangsúlyt kell fektetni a beteg-együttműködés és az eredmények javítása érdekében. Orv Hetil. 2021; 162(26): 1012–1021. Summary. Introduction: Knowledge as a potentially modifiable factor is a prerequisite for appropriate decision making. Objective: In our study, we examined the knowledge level related to renal replacement therapies and its influencing factors among chronic kidney disease patients, in order to identify the patients’ knowledge gaps. At the same time, we provided information, education on kidney transplantation. Method: Factors influencing the patients’ knowledge were evaluated using a multivariate linear regression adjusted for ten factors, where the dependent variable was the knowledge score. During the first data collection of our follow-up study, we contacted patients on the Eurotransplant waiting list, patients undergoing medical evaluation, and patients who refuse a kidney transplant, between 18 and 75 years old. A total of 254 patients were involved in the first round of data collection (recording the basic level of knowledge), and 115 in the second one (after the education). Results: Our results show that patients with both tertiary (β = 1.502, p<0.001) and secondary (β = 2.346, p<0.001) educational attainment achieved higher knowledge scores. Patients with previous kidney transplantation scored 2 points higher than those without (β = 2.024, p<0.001). Moreover, patients with adequate health literacy level achieved significantly higher knowledge scores (β = 1.344, p<0.001). Our results prove the effectiveness of our program since the participants achieved significantly higher scores on the knowledge test, even several months after the education (p<0.001). Conclusion: The gaps we have identified can help the healthcare professionals which areas need to be focused in patient education and self-management programs in order to improve patient collaboration and outcomes. Orv Hetil. 2021; 162(26): 1012–1021.

Melatih Kepemimpinan Perangkat Desa Kebonharjo Kulonprogo: Membangun Sikap Anti Korupsi

2018 ◽  
Vol 1 ◽  
pp. 107
Author(s):  
Adi Heryadi ◽  
Evianawati Evianawati
Keyword(s):  
Transformational Leadership ◽  
Data Collection ◽  
Paired Samples ◽  
Significant Difference ◽  
Before And After ◽  
Post Test ◽  
Sample Test ◽  
Corruption Perception ◽  
Measuring Tool

This study aims to prove whether transformational leadership training is effective for building anti-corruption attitudes of villages in Kebonharjo village, subdistrict Samigaluh Kulonprogo. This research is an experimental research with one group pre and posttest design.Subject design is 17 people from village of 21 candidates registered. Measuring tool used in this research is the scale of anti-corruption perception made by the researcher referring to the 9 anti-corruption values with the value of reliability coefficient of 0.871. The module used as an intervention made by the researcher refers to the transformational leadership dimension (Bass, 1990). The data collected is analyzed by statistical analysis of different test Paired Sample Test. Initial data collection results obtained sign value of 0.770 which means> 0.05 or no significant difference between anti-corruption perception score between before and after training. After a period of less than 1 (one) month then conducted again the measurement of follow-up of the study subjects in the measurement again using the scale of anti-corruption perception. The results of the second data collection were analysed with Paired Samples Test and obtained the value of 0.623 sign meaning p> 0.05 or no significant difference between post test data with follow-up data so that the hypothesis of this study was rejected.

FAKTOR PENGETAHUAN YANG MEMPENGARUHI KETERATURAN IBU BALITA DALAM MENGUNJUNGI POSYANDU DI DESA CIPANGERAN KECAMATAN SAGULING KABUPATEN BANDUNG BARAT TAHUN 2017

2018 ◽  
Vol 5 (2) ◽  
pp. 13-20
Author(s):  
Lia Kamila ◽  
Liawati . ◽  
Suci Lailani Alipah
Keyword(s):  
Public Health ◽  
Data Collection ◽  
Sample Size ◽  
Health Center ◽  
Analytical Method ◽  
Random Sampling ◽  
Research Method ◽  
Cross Sectional ◽  
Public Health Center ◽  
Level Of Knowledge

ABSTRAK Indikator D/S di wilayah kerja Puskesmas Saguling Desa Cipangeran pada tahun 2016 menunjukkan masih rendahnya kunjungan balita dalam kegiatan posyandu dengan rata-rata hanya memcapai 41,5%, sedangkan target standar palayanan kota jumlah D/S yaitu 85%. Tujuan penelitian ini adalah untuk mengetahui keteraturan ibu dalam mengunjungi Posyandu dari faktor pengetahuan di Desa Cipangeran Kecamatan Saguling Kabupaten Bandung Barat tahun 2017. Metode penelitian ini menggunakan metode analitik dengan pendekatan cross sectional. Data yang digunakan adalah data primer. Populasi seluruh balita di wilayah kerja Puskesmas Saguling tahun 2016 sebanyak 424 ibu balita, besar sampel yang diambil 81 ibu balita, pengambilan sampel dengan menggunakan Sampel Random Sampling, pengumpulan data dengan hasil kuesioner berisi pertanyaan untuk mendapatkan data yang berkaitan dengan variabel yang diteliti. Hasil penelitian pengetahuan ibu balita didapatkan hampir setengah berada dikategori cukup yaitu 47 ibu balita (58%), namun masih ada ibu balita yang memiliki pengetahuan baik yaitu 18 ibu balita (22%), dan ibu balita yang memiliki pengetahuan kurang yaitu 16 ibu balita (20%). Kesimpulan dari penelitian didapatkan tingkat pengetahuan ibu balita yang tidak teratur dalam mengunjungi Posyandu di Desa Cipangeran Kecamatan Saguling Kabupaten Bandug Barat hampir setengah ibu balita berpengetahuan cukup. ABSTRACT The D / S indicator in the working area of ​​Saguling Public Health Center of Cipangeran Village in 2016 indicates that the low number of toddler visits in posyandu activities reaches an average of 41.5%, while the standard target for city / city is 85%. The purpose of this study is to determine the regularity of mothers in visiting Posyandu from knowledge factor in Cipangeran Village, Saguling District, West Bandung regency in 2017. This research method using analytical method with cross sectional approach. The data used is primary data.The population of all toddlers in the working area of Saguling Publich Health Center in 2016 were 424 mother, the sample size was 81 mother, using Random Sampling , data collection with questionnaires containing questions to obtain data related to the variables studied. The result of the research of the knowledge of the mother of the toddler is almost sufficient, namely 47 mothers (58%),but there are still mother who have good knowledge that is 18 mother of toddler (22%) and mother with less knowledge that is 16 mother of balita (20%). The conclusion of the research is the level of knowledge of irregular mother in visiting Posyandu in Cipangeran Village, Saguling, of West Bandung district, almost half of the toddler are knowledgeable enough.

scholarly journals The Effect of Javanese Language Videos with a Community Based Interactive Approach Method as an Educational Instrument for Knowledge, Perception, and Adherence amongst Tuberculosis Patients

Pharmacy ◽  
2021 ◽  
Vol 9 (2) ◽  
pp. 86
Author(s):  
Fauna Herawati ◽  
Yuni Megawati ◽  
Aslichah ◽  
Retnosari Andrajati ◽  
Rika Yulia
Keyword(s):  
Intervention Group ◽  
Personal Control ◽  
Control Group ◽  
P Value ◽  
Interactive Approach ◽  
Community Based ◽  
Tuberculosis Patients ◽  
Level Of Knowledge ◽  
The Impact

The long period of tuberculosis treatment causes patients to have a high risk of forgetting or stopping the medication altogether, which increases the risk of oral anti-tuberculosis drug resistance. The patient’s knowledge and perception of the disease affect the patient’s adherence to treatment. This research objective was to determine the impact of educational videos in the local language on the level of knowledge, perception, and adherence of tuberculosis patients in the Regional General Hospital (RSUD) Bangil. This quasi-experimental study design with a one-month follow-up allocated 62 respondents in the intervention group and 60 in the control group. The pre- and post-experiment levels of knowledge and perception were measured with a validated set of questions. Adherence was measured by pill counts. The results showed that the intervention increases the level of knowledge of the intervention group higher than that of the control group (p-value < 0.05) and remained high after one month of follow-up. The perceptions domains that changed after education using Javanese (Ngoko) language videos with the Community Based Interactive Approach (CBIA) method were the timeline, personal control, illness coherence, and emotional representations (p-value < 0.05). More than 95% of respondents in the intervention group take 95% of their pill compared to 58% of respondents in the control group (p-value < 0.05). Utilization of the local languages for design a community-based interactive approach to educate and communicate is important and effective.

scholarly journals 71 Ultrasound directed reduction of Colles’ type distal radial fractures in ED (UDiReCT): a feasibility randomized controlled trial

2020 ◽  
Vol 37 (12) ◽  
pp. 835.3-836
Author(s):  
Hamza Malik ◽  
Andrew Appelboam ◽  
Gordon Taylor ◽  
Daryl Wood ◽  
Karen Knapp
Keyword(s):  
Data Collection ◽  
Controlled Trial ◽  
Wrist Fracture ◽  
Recruitment Rate ◽  
Feasibility Trial ◽  
Point Of Care Ultrasound ◽  
Distal Radial Fractures ◽  
Definitive Trial ◽  
Randomised Controlled

Aims/Objectives/BackgroundWrist fractures are among the commonest injuries seen in the emergency department (ED). Around 25% of these injuries have Colles’ type fracture displacement and undergo manipulation in the ED. In the UK, these manipulations are typically done ‘blind’ without real time imaging and recent observational studies show that over 40% of the injuries go on to require surgical fixation (due to inadequate initial reduction or re-displacement). Point of care ultrasound has been used to guide and improve wrist fracture reductions but it’s effect on subsequent outcome is not established. We set up and ran the UK’s first randomised controlled feasibility trial comparing standard and ultrasound guided ED wrist fracture manipulations to test a definitive trial protocol, data collection and estimate recruitment rate towards a future definitive trial.Methods/DesignWe conducted a 1:1, single blind, parallel group, randomised controlled feasibility trial in two UK hospitals. Adults with Colles’ type distal radial fractures requiring manipulation in the ED were recruited by supervising emergency physicians supported by network research nurses. Participants were randomised to ultrasound directed fracture manipulation (intervention) or standard care with sham ultrasound (controls). The trial was run through Exeter Clinical Trials Unit and consent, randomisation and data collection conducted electronically in REDCap cloud. All participants were followed up at 6 weeks to record any surgical intervention and also underwent baseline and 3 month quality of life (EQ-5D-5L) and wrist function (Patient Rated Wrist Evaluation (PRWE) assessments.Results/ConclusionsWe recruited 47 patients in total, with 23 randomised to the interventional arm and 24 randomised to the control arm. We were able to follow up 100% of the patients for the 6 week follow up. Data analysis and results will be presented at the time of the conference.

scholarly journals Knowledge and understanding of obstetric danger signs among pregnant women attending the antenatal clinic at the National Referral Hospital in Thimphu, Bhutan: a cross-sectional study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Saran Tenzin Tamang ◽  
Thinley Dorji ◽  
Sonam Yoezer ◽  
Thinley Phuntsho ◽  
Phurb Dorji
Keyword(s):  
Pregnant Women ◽  
Knowledge Score ◽  
Antenatal Clinic ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Obstetric Danger Signs ◽  
Danger Signs ◽  
Obstetric Emergencies ◽  
Level Of Knowledge

Abstract Background The third Sustainable Development Goal for 2030 development agenda aims to reduce maternal and newborn deaths. Pregnant women’s understanding of danger signs is an important factor in seeking timely care during emergencies. We assessed knowledge of obstetric danger signs using both recall and understanding of appropriate action required during obstetric emergencies. Methods This was a cross-sectional study among pregnant women attending antenatal clinic at Bhutan’s largest hospital in Thimphu. Recall was assessed against seven obstetric danger signs outlined in the Mother and Child Health Handbook (7 points). Understanding of danger signs was tested using 13 multiple choice questions (13 points). Knowledge was scored out of 20 points and reported as ‘good’ (≥80%), ‘satisfactory’ (60–79%) and ‘poor’ (< 60%). Correlation between participant characteristics and knowledge score as well as number of danger signs recalled was tested using Pearson’s correlation coefficient. Association between knowledge score and participant characteristics was tested using t-tests (and Kruskal-Wallis test) for numeric variables. Socio-demographic and clinical characteristics associated with the level of knowledge ('good’ versus ‘satisfactory’ and ‘poor’ combined) were assessed with odds ratios using a log-binomial regression model. All results with p < 0.05 were considered significant. Results Four hundred and twenty-two women responded to the survey (response rate = 96.0%). Mean (±SD) knowledge score was 12 (±2.5). Twenty women (4.7%) had ‘good’ knowledge, 245 (58.1%) had ‘satisfactory’ knowledge and 157 (37.2%) had ‘poor’ knowledge. The median number of danger signs recalled was 2 (IQR 1, 3) while 68 women (20.3%) could not recall any danger signs. Most women were knowledgeable about pre-labour rupture of membranes (96.0%) while very few women were knowledgeable about spotting during pregnancy (19.9%). Both knowledge score and number of danger signs recalled had significant correlation with the period of gestation. Women with previous surgery on the reproductive tract had higher odds of having ‘good’ level of knowledge. Conclusions Most pregnant women had ‘satisfactory’ knowledge score with poor explicit recall of danger signs. However, women recognized obstetric emergencies and identified the appropriate action warranted.

scholarly journals Routine clinical care data from thirteen cardiac outpatient clinics: design of the Cardiology Centers of the Netherlands (CCN) database

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Sophie H. Bots ◽  
Klaske R. Siegersma ◽  
N. Charlotte Onland-Moret ◽  
Folkert W. Asselbergs ◽  
G. Aernout Somsen ◽  
...  
Keyword(s):  
Risk Factors ◽  
General Practitioner ◽  
Data Collection ◽  
The Netherlands ◽  
Strong Base ◽  
Daily Care ◽  
Cardiac Symptoms ◽  
Number Of Patients ◽  
Patient Groups

Abstract Background Despite the increasing availability of clinical data due to the digitalisation of healthcare systems, data often remain inaccessible due to the diversity of data collection systems. In the Netherlands, Cardiology Centers of the Netherlands (CCN) introduced “one-stop shop” diagnostic clinics for patients suspected of cardiac disease by their general practitioner. All CCN clinics use the same data collection system and standardised protocol, creating a large regular care database. This database can be used to describe referral practices, evaluate risk factors for cardiovascular disease (CVD) in important patient subgroups, and develop prediction models for use in daily care. Construction and content The current database contains data on all patients who underwent a cardiac workup in one of the 13 CCN clinics between 2007 and February 2018 (n = 109,151, 51.9% women). Data were pseudonymised and contain information on anthropometrics, cardiac symptoms, risk factors, comorbidities, cardiovascular and family history, standard blood laboratory measurements, transthoracic echocardiography, electrocardiography in rest and during exercise, and medication use. Clinical follow-up is based on medical need and consisted of either a repeat visit at CCN (43.8%) or referral for an external procedure in a hospital (16.5%). Passive follow-up via linkage to national mortality registers is available for 95% of the database. Utility and discussion The CCN database provides a strong base for research into historically underrepresented patient groups due to the large number of patients and the lack of in- and exclusion criteria. It also enables the development of artificial intelligence-based decision support tools. Its contemporary nature allows for comparison of daily care with the current guidelines and protocols. Missing data is an inherent limitation, as the cardiologist could deviate from standardised protocols when clinically indicated. Conclusion The CCN database offers the opportunity to conduct research in a unique population referred from the general practitioner to the cardiologist for diagnostic workup. This, in combination with its large size, the representation of historically underrepresented patient groups and contemporary nature makes it a valuable tool for expanding our knowledge of cardiovascular diseases. Trial registration: Not applicable.

scholarly journals Successful long-term management of recurrent focal segmental glomerulosclerosis after kidney transplantation with costimulation blockade

2020 ◽  
Author(s):  
Thomas Mühlbacher ◽  
Kerstin Amann ◽  
Moritz Mahling ◽  
Silvio Nadalin ◽  
Nils Heyne ◽  
...  
Keyword(s):  
Kidney Transplantation ◽  
Focal Segmental Glomerulosclerosis ◽  
Costimulation Blockade ◽  
Segmental Glomerulosclerosis ◽  
Remission Maintenance ◽  
Maintenance Immunosuppression ◽  
Therapeutic Concepts ◽  
Allograft Outcome

Abstract Recurrence of primary focal segmental glomerulosclerosis (FSGS) occurs in up to 50% of patients after kidney transplantation and is associated with poor allograft outcome. Novel therapeutic concepts directly target podocyte function via B7-1 with inconsistent response. We present the case of a 19 yr. old patient with recurrent primary FSGS early after living donor kidney transplantation. Plasmapheresis and rituximab did not induce remission. Repetitive abatacept administration was able to achieve partial remission. Maintenance immunosuppression was subsequently switched to a belatacept-based CNI-free immunosuppression, resulting in sustained complete remission with excellent allograft function throughout a follow-up of more than 56 months.

scholarly journals The Use of the Oxygenated AirdriveTM Machine Perfusion System in Kidney Graft Preservation: A Clinical Pilot Study

2020 ◽  
Vol 61 (6) ◽  
pp. 153-162
Author(s):  
Julia H.E. Houtzager ◽  
Sebastiaan David Hemelrijk ◽  
Ivo C.J.H. Post ◽  
Mirza M Idu ◽  
Frederike J. Bemelman ◽  
...  
Keyword(s):  
Kidney Transplantation ◽  
Pilot Study ◽  
Adverse Events ◽  
Deceased Donor ◽  
Kidney Graft ◽  
Machine Perfusion ◽  
End Points ◽  
Viable Solution ◽  
Technical Failures

Background: The shortage of donor kidneys has led to the use of marginal donors, e.g., those whose kidneys are donated after circulatory death. Preservation of the graft by hypothermic machine perfusion (HMP) provides a viable solution to reduce warm ischemic damage. This pilot study was undertaken to assess the feasibility and patient safety of the AirdriveTM HMP system in clinical kidney transplantation. Methods: Five deceased-donor kidneys were preserved using the oxygenated Airdrive HMP system between arrival at the recipient center (Amsterdam UMC) and implantation in the patient. The main study end-points were adverse effects due to the use of Airdrive HMP. Secondary end-points were clinical outcomes and perfusion parameters. All events occurring during the transplantation procedure or within 1 month of follow-up were monitored. Results: Five patients were included in this pilot study. No technical failures were observed during the preservation period using the Airdrive HMP. Mean perfusion parameters were: duration 8.5 h (3–15 h), pressure 25 mm Hg (18–25 mm Hg), flow 49.77 mL/min (19–58 mL/min), resistance 0.57 mm Hg/min/mL (0.34–1.3 mm Hg/min/mL), and temperature 8.2 °C (2–13°C). Mean cold ischemia time (CIT) was 20.2 h (11–29.5 h). No adverse events or technical failures were observed during preservation and transplantation or during the 1-month follow-up. Conclusions: This pilot study showed the feasibility of the use of the Airdrive HMP system with no adverse events in clinical kidney transplantation.

scholarly journals Communicative health literacy in patients with non-communicable diseases in Ethiopia: a cross-sectional study

2021 ◽  
Vol 49 (1) ◽  
Author(s):  
Desalew Tilahun ◽  
Abebe Abera ◽  
Gugsa Nemera
Keyword(s):  
Health Literacy ◽  
Cross Sectional Study ◽  
Communicable Diseases ◽  
Source Population ◽  
Sectional Study ◽  
Cross Sectional ◽  
Non Communicable Diseases ◽  
Health Literacy Level ◽  
Literacy Level

Abstract Background Health literacy plays a prominent role in empowering individuals for prevention as well as management of non-communicable diseases (NCDs). However, there is paucity of information on the health literacy of patients with non-communicable diseases in Ethiopia. Therefore, this study aimed to assess communicative health literacy and associated factors in patients with NCDs on follow-up at Jimma Medical Center (JMC), Ethiopia. Methods A cross-sectional study was conducted from 4 May 2020 to 4 July 2020 with 408 randomly selected adult patients, attending outpatient department of JMC in Ethiopia. The final sample size was obtained by using single population proportion formula. All patients with NCDs who were on follow-up at chronic illness clinic, JMC, were used as a source population. All eligible patients with NCDs who fulfilled the inclusion criteria were included in this study. A simple random sampling technique was used to recruit study participants. Data were collected through structured interviewer administered questionnaires on the six of nine health literacy domains using Health Literacy Questionnaire (HLQ) containing 30 items, socio-demographic and socio-economic characteristics, disease-related factors, and health information sources. Multivariable logistic regression was executed to determine the associations. Result Descriptive analysis shows more than half of the respondents in four of the six health literacy domains had high communicative health literacy level (CHLL). The proportion of people with high CHLL across each of the domains was as follows: health care provider support (56.1%), social support for health (53.7%), active engagement with a healthcare provider (56.1%), and navigating healthcare system (53.4%). We found educational status was significantly associated with five of six health literacy domains whereas number of sources was associated with four of six health literacy domains. Conclusion The overall findings of the current study indicate that health literacy levels vary according to socio-demographic and disease characteristics of patients. Thus, healthcare professionals should assess patients’ health literacy level and tailor information and support to the health literacy skills and personal context of their patients.

scholarly journals Severe hypercalcaemia early after kidney transplantation in two patients with severe secondary hyperparathyroidism previously treated with etelcalcetide

2021 ◽  
Author(s):  
Guillaume Dachy ◽  
Jean-Michel Pochet ◽  
Laura Labriola ◽  
Antoine Buemi ◽  
Valentine Gillion ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Transplantation ◽  
Significant Proportion ◽  
High Serum ◽  
Mineral And Bone Disorder ◽  
Parathyroid Adenomas ◽  
Bone Disorder ◽  
Previously Treated ◽  
Severe Hypercalcaemia

Abstract Cinacalcet and, more recently, etelcalcetide revolutionized the treatment of chronic kidney disease–mineral and bone disorder (CKD–MBD). Kidney transplant (KT) usually improves CKD–MBD. However, a significant proportion of KT recipients have high serum calcium levels, not requiring any treatment. We report two patients previously treated with etelcalcetide who developed severe (&gt;3.3 mmol/L) hypercalcaemia in the early post-KT course, requiring parathyroidectomy. Pathological studies showed parathyroid adenomas and hyperplasia. One patient had a graft biopsy showing numerous intratubular calcium phosphate crystals. These observations should prompt pharmacovigilance studies and careful follow-up of KT recipients previously treated with etelcalcetide.

Sign in / Sign up

Export Citation Format

Share Document