Retrotransposons: Metaparasites and Agents of Genome Evolution

2006 ◽  
Vol 52 (3-4) ◽  
pp. 319-330 ◽  
Author(s):  
François Sabot ◽  
Ruslan Kalendar ◽  
Marko Jääskeläinen ◽  
Chang Wei ◽  
Jaakko Tanskanen ◽  
...  

Transposable elements comprise the bulk of higher plant genomes. The majority of these elements are the Class I LTR retrotransposons, which transpose via an RNA intermediate in a "Copy-and-Paste" mechanism. Because retrotransposons use cellular resources and their own enzymes to replicate independently of the genome as a whole, and have thereby become in many cases more predominant than the cellular genes, they have been considered "selfish DNA" and nuclear parasites. They are thought to share many features of the internal life cycle of retroviruses such as HIV (lentiviruses). However, whereas at least some of the retroviruses arriving in an organism during an infection must be functional in order for the infection to proceed, some LTR retrotransposon families appear to completely lack active members even though they remain mobile. Furthermore, the process of retrotransposition is inherently error-prone and mutagenic, giving rise to "pseudospecies," or clusters of imperfect copies. The non-autonomous retrotransposons are able to cis- and trans-parasitize host retrotransposons to gain mobility, much as do defective interfering particles of RNA viruses. Hence, a complex dynamic is set up, whereby the impact of retrotransposons on genomes can be under selection on the organismal level; the impact of non-autonomous retrotransposons on autonomous ones can likewise be under selection if there is selection on the autonomous elements themselves. We are exploring the retrotransposon life cycle and the causes and possible consequences of non-autonomy at each stage regarding genome evolution.

2011 ◽  
Vol 204-210 ◽  
pp. 1659-1664
Author(s):  
Qing Wen Sun ◽  
Liu Huai

Research on the account sale only focused on account sale itself, and it can’t support enterprises sufficiently to make decision of account sale in theory and methodology. So considering the impact of account sale on cash sale in the process of account sale of enterprises, the demand shifting of cash sale because of account sale, the cash sale and account sale characteristics in declining period of products and applying the theories of product life cycle (PLC) and dynamic programming, the paper set up the optimal model of decision-making in declining period of life cycle for the purpose of maximizing total profit of cash sale and account sale and made out the optimal starting time, then determined the best credit policy by exploring the relation between the optimal starting time of account sale and enterprises making credit policies. The paper provides certain proof for enterprises to make reasonable and economical credit policies.


2018 ◽  
Vol 1 (1) ◽  
pp. 1
Author(s):  
Murisal Murisal

Motif and Impact of Early Marriage in Indarung Ngalau Batu Gadang.Penelitian is motivated by teenagers who married early on. Today, young men and women have a tendency to be less prepared to enter the home life, they are only ready to marry (ready here can be interpreted, maturity in terms of financial, understand what the meaning of marriage according to marriage law) is the bond of inner birth between a man and a woman as husband and wife for the purpose of forming a happy and eternal family (household) based on the Supreme Godhead while they are not ready to set up a home, whereas to build a household requires preparation both physically and spiritually . The purpose of this study to determine the motives underlying adolescents to make early marriage and the impact caused in the household as a result of the marriage.


2003 ◽  
Author(s):  
Shayne Brannman ◽  
Eric W. Christensen ◽  
Ronald H. Nickel ◽  
Cori Rattelman ◽  
Richard D. Miller

Author(s):  
Mark Burden

Much eighteenth-century Dissenting educational activity was built on an older tradition of Puritan endeavour. In the middle of the seventeenth century, the godly had seen education as an important tool in spreading their ideas but, in the aftermath of the Restoration, had found themselves increasingly excluded from universities and schools. Consequently, Dissenters began to develop their own higher educational institutions (in the shape of Dissenting academies) and also began to set up their own schools. While the enforcement of some of the legal restrictions that made it difficult for Dissenting institutions diminished across the eighteenth century, the restrictions did not disappear entirely. While there has been considerable focus on Dissenting academies and their contribution to debates about doctrinal orthodoxy, the impact of Dissenting schools was also considerable.


The theory of the vibrations of the pianoforte string put forward by Kaufmann in a well-known paper has figured prominently in recent discussions on the acoustics of this instrument. It proceeds on lines radically different from those adopted by Helmholtz in his classical treatment of the subject. While recognising that the elasticity of the pianoforte hammer is not a negligible factor, Kaufmann set out to simplify the mathematical analysis by ignoring its effect altogether, and treating the hammer as a particle possessing only inertia without spring. The motion of the string following the impact of the hammer is found from the initial conditions and from the functional solutions of the equation of wave-propagation on the string. On this basis he gave a rigorous treatment of two cases: (1) a particle impinging on a stretched string of infinite length, and (2) a particle impinging on the centre of a finite string, neither of which cases is of much interest from an acoustical point of view. The case of practical importance treated by him is that in which a particle impinges on the string near one end. For this case, he gave only an approximate theory from which the duration of contact, the motion of the point struck, and the form of the vibration-curves for various points of the string could be found. There can be no doubt of the importance of Kaufmann’s work, and it naturally becomes necessary to extend and revise his theory in various directions. In several respects, the theory awaits fuller development, especially as regards the harmonic analysis of the modes of vibration set up by impact, and the detailed discussion of the influence of the elasticity of the hammer and of varying velocities of impact. Apart from these points, the question arises whether the approximate method used by Kaufmann is sufficiently accurate for practical purposes, and whether it may be regarded as applicable when, as in the pianoforte, the point struck is distant one-eighth or one-ninth of the length of the string from one end. Kaufmann’s treatment is practically based on the assumption that the part of the string between the end and the point struck remains straight as long as the hammer and string remain in contact. Primâ facie , it is clear that this assumption would introduce error when the part of the string under reference is an appreciable fraction of the whole. For the effect of the impact would obviously be to excite the vibrations of this portion of the string, which continue so long as the hammer is in contact, and would also influence the mode of vibration of the string as a whole when the hammer loses contact. A mathematical theory which is not subject to this error, and which is applicable for any position of the striking point, thus seems called for.


Foods ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 873
Author(s):  
Francisco Javier Flor-Montalvo ◽  
Agustín Sánchez-Toledo Ledesma ◽  
Eduardo Martínez Cámara ◽  
Emilio Jiménez-Macías ◽  
Jorge Luis García-Alcaraz ◽  
...  

Natural stoppers are a magnificent closure for the production of aging wines and unique wines, whose application is limited by the availability of raw materials and more specifically of cork sheets of different thickness and quality. The growing demand for quality wine bottle closures leads to the search for alternative stopper production. The two-piece stopper is an alternative since it uses non-usable plates in a conventional way for the production of quality caps. The present study has analyzed the impact of the manufacture of these two-piece stoppers using different methodologies and for different dimensions by developing an LCA (Life Cycle Assessment), concluding that the process phases of the plate, its boiling, and its stabilization, are the phases with the greatest impact. Likewise, it is detected that the impacts in all phases are relatively similar (for one kg of net cork produced), although the volumetric difference between these stoppers represents a significant difference in impacts for each unit produced.


Author(s):  
M. von der Thannen ◽  
S. Hoerbinger ◽  
C. Muellebner ◽  
H. Biber ◽  
H. P. Rauch

AbstractRecently, applications of soil and water bioengineering constructions using living plants and supplementary materials have become increasingly popular. Besides technical effects, soil and water bioengineering has the advantage of additionally taking into consideration ecological values and the values of landscape aesthetics. When implementing soil and water bioengineering structures, suitable plants must be selected, and the structures must be given a dimension taking into account potential impact loads. A consideration of energy flows and the potential negative impact of construction in terms of energy and greenhouse gas balance has been neglected until now. The current study closes this gap of knowledge by introducing a method for detecting the possible negative effects of installing soil and water bioengineering measures. For this purpose, an environmental life cycle assessment model has been applied. The impact categories global warming potential and cumulative energy demand are used in this paper to describe the type of impacts which a bioengineering construction site causes. Additionally, the water bioengineering measure is contrasted with a conventional civil engineering structure. The results determine that the bioengineering alternative performs slightly better, in terms of energy demand and global warming potential, than the conventional measure. The most relevant factor is shown to be the impact of the running machines at the water bioengineering construction site. Finally, an integral ecological assessment model for applications of soil and water bioengineering structures should point out the potential negative effects caused during installation and, furthermore, integrate the assessment of potential positive effects due to the development of living plants in the use stage of the structures.


2021 ◽  
Vol 11 (9) ◽  
pp. 3820
Author(s):  
Noelia Llantoy ◽  
Gabriel Zsembinszki ◽  
Valeria Palomba ◽  
Andrea Frazzica ◽  
Mattia Dallapiccola ◽  
...  

With the aim of contributing to achieving the decarbonization of the energy sector, the environmental impact of an innovative system to produce heating and domestic hot water for heating demand-dominated climates is assessed is evaluated. The evaluation is conducted using the life cycle assessment (LCA) methodology and the ReCiPe and IPCC GWP indicators for the manufacturing and operation stages, and comparing the system to a reference one. Results show that the innovative system has a lower overall impact than the reference one. Moreover, a parametric study to evaluate the impact of the refrigerant is carried out, showing that the impact of the overall systems is not affected if the amount of refrigerant or the impact of refrigerant is increased.


2021 ◽  
Vol 13 (9) ◽  
pp. 5322
Author(s):  
Gabriel Zsembinszki ◽  
Noelia Llantoy ◽  
Valeria Palomba ◽  
Andrea Frazzica ◽  
Mattia Dallapiccola ◽  
...  

The buildings sector is one of the least sustainable activities in the world, accounting for around 40% of the total global energy demand. With the aim to reduce the environmental impact of this sector, the use of renewable energy sources coupled with energy storage systems in buildings has been investigated in recent years. Innovative solutions for cooling, heating, and domestic hot water in buildings can contribute to the buildings’ decarbonization by achieving a reduction of building electrical consumption needed to keep comfortable conditions. However, the environmental impact of a new system is not only related to its electrical consumption from the grid, but also to the environmental load produced in the manufacturing and disposal stages of system components. This study investigates the environmental impact of an innovative system proposed for residential buildings in Mediterranean climate through a life cycle assessment. The results show that, due to the complexity of the system, the manufacturing and disposal stages have a high environmental impact, which is not compensated by the reduction of the impact during the operational stage. A parametric study was also performed to investigate the effect of the design of the storage system on the overall system impact.


2021 ◽  
Vol 13 (10) ◽  
pp. 5726
Author(s):  
Aleksandra Wewer ◽  
Pinar Bilge ◽  
Franz Dietrich

Electromobility is a new approach to the reduction of CO2 emissions and the deceleration of global warming. Its environmental impacts are often compared to traditional mobility solutions based on gasoline or diesel engines. The comparison pertains mostly to the single life cycle of a battery. The impact of multiple life cycles remains an important, and yet unanswered, question. The aim of this paper is to demonstrate advances of 2nd life applications for lithium ion batteries from electric vehicles based on their energy demand. Therefore, it highlights the limitations of a conventional life cycle analysis (LCA) and presents a supplementary method of analysis by providing the design and results of a meta study on the environmental impact of lithium ion batteries. The study focuses on energy demand, and investigates its total impact for different cases considering 2nd life applications such as (C1) material recycling, (C2) repurposing and (C3) reuse. Required reprocessing methods such as remanufacturing of batteries lie at the basis of these 2nd life applications. Batteries are used in their 2nd lives for stationary energy storage (C2, repurpose) and electric vehicles (C3, reuse). The study results confirm that both of these 2nd life applications require less energy than the recycling of batteries at the end of their first life and the production of new batteries. The paper concludes by identifying future research areas in order to generate precise forecasts for 2nd life applications and their industrial dissemination.


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