PIPERINE-LOADED CHITOSAN NANOPARTICLES: PREPARATION AND CHARACTERIZATION
2021 ◽
Vol 59
(4)
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pp. 480
Abstract – HCTN7. Plasma cholesterol level plays an important role in atherosclerosis and cardiovascular diseases. Piperine, an alkaloid form of black pepper is known to reduce cholesterol uptake. In this paper, piperine-loaded chitosan nanoparticles (CTS-PIP NPs) were prepared by ionic gelation method. Molecular interactions among the components were confirmed by FT-IR spectroscopy. Transmission electron microscopy (TEM) images revealed spherical-shaped nanoparticles with diameter of <100 nm. CTS-PIP NPs displayed positive ζ-potential(ZP) of about 31.6 mV. Dynamic light scattering (DLS) particle size (PS) distribution analysis indicated the mean particle size of CTS-PIP NPs was 245.9 nm, polydispersity index of 31%
2017 ◽
Vol 50
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pp. 18-31
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2018 ◽
Vol 21
(2)
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pp. 92-97
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