The kinetic behavior of antioxidant activity and the stability of aqueous and organic polyphenol extracts from navel orange peel

Abstract Polygonatum odoratum (Mill.) Druce (POD) is a natural plant widely used for food and medicine, thanks to its rich content of a strong antioxidant agent called homoisoflavones. However, food processing methods could affect the stability of POD flavones, resulting in changes to their antioxidant activity. This study attempts to evaluate the antioxidant activity of POD flavones subject to different processing methods and determines which method could preserve the antioxidant activity of POD flavones. Therefore, flavones were extracted from POD samples, which had been treated separately with one of the four processing methods: extrusion, baking, high-pressure treatment, and yeast fermentation. After that, the antioxidant activity of the flavones was subject to in vivo tests in zebrafish embryos. The results show that yeast fermentation had the least disruption to the antioxidant activity of POD flavones, making it the most suitable food processing method for POD. By contrast, extrusion and high-pressure treatment both slightly weakened the antioxidant activity of the flavones and should be avoided in food processing. The research results provide a reference for the development and utilization of POD and the protection of its biological activity.

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Complexes of Copper and Iron with Pyridoxamine, Ascorbic Acid, and a Model Amadori Compound: Exploring Pyridoxamine’s Secondary Antioxidant Activity

Antioxidants ◽

10.3390/antiox10020208 ◽

2021 ◽

Vol 10 (2) ◽

pp. 208

Author(s):

Guillermo García-Díez ◽

Roger Monreal-Corona ◽

Nelaine Mora-Diez

Keyword(s):

Antioxidant Activity ◽

Ascorbic Acid ◽

Rate Constant ◽

Stable Complex ◽

Aqueous Environment ◽

Oh Radicals ◽

Bidentate Ligands ◽

Superoxide Radical Anion ◽

Amadori Compound ◽

The Stability

The thermodynamic stability of 11 complexes of Cu(II) and 26 complexes of Fe(III) is studied, comprising the ligands pyridoxamine (PM), ascorbic acid (ASC), and a model Amadori compound (AMD). In addition, the secondary antioxidant activity of PM is analyzed when chelating both Cu(II) and Fe(III), relative to the rate constant of the first step of the Haber-Weiss cycle, in the presence of the superoxide radical anion (O2•−) or ascorbate (ASC−). Calculations are performed at the M05(SMD)/6-311+G(d,p) level of theory. The aqueous environment is modeled by making use of the SMD solvation method in all calculations. This level of theory accurately reproduces the experimental data available. When put in perspective with the stability of various complexes of aminoguanidine (AG) (which we have previously studied), the following stability trends can be found for the Cu(II) and Fe(III) complexes, respectively: ASC < AG < AMD < PM and AG < ASC < AMD < PM. The most stable complex of Cu(II) with PM (with two bidentate ligands) presents a ΔGf0 value of −35.8 kcal/mol, whereas the Fe(III) complex with the highest stability (with three bidentate ligands) possesses a ΔGf0 of −58.9 kcal/mol. These complexes can significantly reduce the rate constant of the first step of the Haber-Weiss cycle with both O2•− and ASC−. In the case of the copper-containing reaction, the rates are reduced up to 9.70 × 103 and 4.09 × 1013 times, respectively. With iron, the rates become 1.78 × 103 and 4.45 × 1015 times smaller, respectively. Thus, PM presents significant secondary antioxidant activity since it is able to inhibit the production of ·OH radicals. This work concludes a series of studies on secondary antioxidant activity and allows potentially new glycation inhibitors to be investigated and compared relative to both PM and AG.

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Optimization of Ultrasound-Assisted Extraction via Sonotrode of Phenolic Compounds from Orange By-Products

Foods ◽

10.3390/foods10051120 ◽

2021 ◽

Vol 10 (5) ◽

pp. 1120

Author(s):

María del Carmen Razola-Diaz ◽

Eduardo Jesús Guerra-Hernández ◽

Celia Rodríguez-Pérez ◽

Ana María Gómez-Caravaca ◽

Belén García-Villanova ◽

...

Keyword(s):

Antioxidant Activity ◽

Phenolic Compounds ◽

High Performance ◽

Phenolic Content ◽

Orange Peel ◽

Polar Compounds ◽

Ultrasound Assisted Extraction ◽

Assisted Extraction ◽

Quantitative Analyses ◽

Ultrasound Assisted

Orange peel is the main by-product from orange juice industry. It is a known source of bioactive compounds, mostly phenolic compounds, and it has been widely studied for its healthy activities. Thus, this research focuses on the establishment of ultrasound-assisted extraction of phenolic compounds in orange peel using a sonotrode. For this purpose, a Box–Behnken design of 27 experiments was carried out with four independent factors—ratio ethanol/water (v/v), time (min), amplitude (%), and pulse (%). Quantitative analyses of phenolic compounds were performed and the antioxidant activity was measured by ABTS and DPPH methods. The validity of the experimental design was confirmed by ANOVA and the optimal sonotrode extraction conditions were obtained by response surface methodology (RSM). The extracts obtained in the established conditions were analyzed by High Performance Liquid Chromatography (HPLC) coupled to mass spectrometer detector and 74 polar compounds were identified. The highest phenolic content and antioxidant activity were obtained using 45/55 ethanol/water (v/v), 35 min, amplitude 90% (110 W), and pulse 100%. The established method allows an increment of phenolics recovery up to 60% higher than a conventional extraction. Moreover, the effect of drying on phenolic content was also evaluated.

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Effect of Water Activity on the Stability to Oxidation of Spray-Dried Encapsulated Orange Peel Oil Using Mesquite Gum (Prosopis Juliflora) as Wall Material

Journal of Food Science ◽

10.1111/j.1365-2621.2002.tb11385.x ◽

2002 ◽

Vol 67 (1) ◽

pp. 206-211 ◽

Cited By ~ 87

Author(s):

C.I. Beristain ◽

E. Azuara ◽

E.J. Vernon-Carter

Keyword(s):

Water Activity ◽

Orange Peel ◽

Prosopis Juliflora ◽

Wall Material ◽

Effect Of Water ◽

Orange Peel Oil ◽

The Stability ◽

Spray Dried ◽

Mesquite Gum ◽

Peel Oil

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Ultrasonic-Supercritical CO2-Assisted Extraction and Component Analysis of Navel Orange Peel Pigment

Asian Journal of Chemistry ◽

10.14233/ajchem.2015.17816 ◽

2015 ◽

Vol 27 (6) ◽

pp. 2137-2140

Author(s):

Xianchun Yu ◽

Ying Wu ◽

Delin Sun ◽

Tian Tian

Keyword(s):

Supercritical Co2 ◽

Orange Peel ◽

Component Analysis ◽

Navel Orange ◽

Assisted Extraction

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Enhancement of Chemical Stability and Dermal Delivery of Cordyceps militaris Extracts by Nanoemulsion

Nanomaterials ◽

10.3390/nano10081565 ◽

2020 ◽

Vol 10 (8) ◽

pp. 1565 ◽

Cited By ~ 1

Author(s):

Pachabadee Marsup ◽

Kankanit Yeerong ◽

Waranya Neimkhum ◽

Jakkapan Sirithunyalug ◽

Songyot Anuchapreeda ◽

...

Keyword(s):

Antioxidant Activity ◽

Chemical Stability ◽

Radical Scavenging Activity ◽

Skin Irritation ◽

Radical Scavenging ◽

Water Extract ◽

Cordyceps Militaris ◽

Alpha Tocopherol ◽

Dermal Delivery ◽

The Stability

This study aimed to develop nanoemulsions for enhancing chemical stability and dermal delivery of Cordyceps militaris extracts. C. militaris was extracted by maceration and infusion. The extracts were investigated for cordycepin, phenolic, and flavonoid content. The antioxidant activity was investigated by in vitro spectrophotometric methods. The irritation profile was investigated by hen’s egg-chorioallantoic membrane test. Nanoemulsions were developed using high-pressure homogenizer. C. militaris extract was incorporated into the nanoemulsion and investigated for safety, release profile, permeation, and skin retention. The results demonstrated that water extract (CW) contained the significantly highest content of cordycepin, phenolics, and flavonoids, which were responsible for antioxidant activity. CW was the most potent antioxidant. CW possessed comparable 2,2′-diphenyl-1-picrylhydrazyl radical scavenging activity and lipid peroxidation inhibition to l-ascorbic acid (96.9 ± 3.1%) and alpha-tocopherol (87.2 ± 1.0%). Consequently, ten mg/mL of CW was incorporated into nanoemulsions composing of sugar squalene, Tween® 85, and deionized water. Nanoemulsion, which had the smallest internal droplet size (157.1 ± 2.6 nm), enhanced the stability of CW, had no cytotoxicity effect and no skin irritation, released the most CW (0.9 ± 0.0% w/w after 24 h), and delivered the highest CW into the skin layer (33.5 ± 0.7% w/w). Therefore, nanoemulsion was suggested for enhancing the stability and dermal delivery of CW.

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Stability, antioxidant activity and in vitro bile acid-binding of green, black and dark tea polyphenols during simulated in vitro gastrointestinal digestion

RSC Advances ◽

10.1039/c5ra18784b ◽

2015 ◽

Vol 5 (112) ◽

pp. 92089-92095 ◽

Cited By ~ 18

Author(s):

Zhengmei Wu ◽

Jianwen Teng ◽

Li Huang ◽

Ning Xia ◽

Baoyao Wei

Keyword(s):

Antioxidant Activity ◽

Bile Acid ◽

Phenolic Compounds ◽

Binding Activity ◽

Tea Polyphenols ◽

Gastrointestinal Digestion ◽

In Vitro Gastrointestinal Digestion ◽

Bile Acid Binding ◽

The Stability

The stability and antioxidant activity of phenolic compounds, as well as the bile acid-binding activity of green, black, raw liubao and aged liubao tea duringin vitrogastrointestinal digestion were evaluated.

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Journal of Food Quality Thermal Degradation of Plum Anthocyanins: Comparison of Kinetics from Simple to Natural Systems

Journal of Food Quality ◽

10.1155/2018/1598756 ◽

2018 ◽

Vol 2018 ◽

pp. 1-10 ◽

Cited By ~ 2

Author(s):

Mihaela Turturică ◽

Nicoleta Stănciuc ◽

Claudia Mureșan ◽

Gabriela Râpeanu ◽

Constantin Croitoru

Keyword(s):

Antioxidant Activity ◽

Citric Acid ◽

Thermal Degradation ◽

Fluorescence Spectra ◽

Degradation Rate ◽

Natural Systems ◽

Degradation Rate Constant ◽

Higher Temperature ◽

Lower Temperature ◽

The Stability

The stability of anthocyanin was assessed over a temperature range of 50–120°C in different simulated plum juices in order to compare the thermal behavior in the presence of certain compounds. The results were correlated with the antioxidant activity and intrinsic fluorescence spectra. The results suggested significant changes, especially at higher temperature; hence, increase in the fluorescence intensity and some bathochromic and hypsochromic shifts were observed. Anthocyanins in natural matrices presented the highest rate for degradation, followed by the anthocyanins in juices with sugars. Values of the activation energies were 42.40 ± 6.87 kJ/mol for the degradation in water, 40.70 ± 4.25 kJ/mol for the juices with citric acid, 23.03 ± 3.53 kJ/mol for the juices containing sugars, 35.99 ± 3.60 kJ/mol for simulated juices with mixture, and 14.19 ± 2.39 kJ/mol for natural juices. A protective effect of sugars was evidenced, whereas in natural matrices, the degradation rate constant showed lower temperature dependence.

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