scholarly journals IDENTIFICATION OF IMAGE AREA CONCEPT OF TSUNAMI DISASTER RESPONSE IN COASTAL SPATIAL Case Study : Serangan Island, Denpasar, Bali

2020 ◽  
Vol 2 (2) ◽  
pp. 176-189
Author(s):  
I Gede Surya Darmawan
Keyword(s):  
Disaster Response ◽  
Provincial Government ◽  
Disaster Mitigation ◽  
Residential Areas ◽  
White Sand ◽  
Tsunami Disaster ◽  
Image Area ◽  
Communal Space ◽  
The Many ◽  
And Function

Serangan Island is one of the favourite tourist destinations in Bali which is the result of reclamation in 1995-1998, famous for its image as "Turtle Island", the presence of Sakenan Temple, white sand beaches, marine tourism, watersport, coral reef cultivation and seaweed, and the the fishing village of Bugis and Bali. However, behind the many tourism potentials, Serangan Island is threatened with earthquakes and tsunamis because the island is located on the south coast facing the Indian Ocean and the island's relatively low topography and inland elevation. In 2014, the Provincial Government of Bali through the Regional Disaster Management Agency (BPBD) built a communal space in the form of a Temporary Evacuation Place (TES) which is integrated with the Serangan Village Market. This research will identify in detail the implementation of the concept of the image of the disaster response area in the coastal area of Serangan Island. The research method used is descriptive qualitative with purposive sampling, with the use of the image theory of the area and disaster response architecture as the basis of this research. The results of the study show that the concept of the image of the Serangan Island area has also applied the concept of disaster mitigation both in architecture and in spatial planning. This identification has been seen in the concept of paths, edges, districts, nodes and landmarks. The main attacks are on residential areas, although in some parts the potential and function of disaster mitigation aspects need to be maximized.Keywords – image area concept, tsunami disaster response, coastal spatial

scholarly journals DISASTER RISK MANAGEMENT in PALU CITY

2019 ◽  
Author(s):  
muhammad ahsan samad
Keyword(s):  
Natural Disasters ◽  
Natural Disaster ◽  
Disaster Management ◽  
Disaster Risk ◽  
Disaster Mitigation ◽  
Tsunami Disaster ◽  
Community Preparedness ◽  
The Many ◽  
The City

Palu City is one of the provincial capitals in Indonesia which is right on the Equator line. In addition, this city is one of the many regions in the eastern part of Indonesia that have a considerable potential for natural disasters. The natural disaster that occurred in Palu on September 28, 2018 consisted of three types of disasters, the first was an earthquake, the second tsunami and the last was liquefaction. This natural disaster caused damage to supporting infrastructure and thousands of people died. The large number of fatalities illustrates that the preparation and preparedness of the community and local government authorities are still low, mainly due to a lack of knowledge and concern for these natural phenomena and their consequences. The earthquake and tsunami disaster that took place in the city of Palu Sigi and Donggala was a momentum to change the paradigm of disaster management by increasing community preparedness. This research tells the story of the phenomenon of the three natural disasters, also tried to explain the steps and design of disaster mitigation. Disaster Mitigation must be implemented to reduce the risk of natural disasters. Public policy about community preparedness towards disaster management is very important and urgent to do in order to reduce disaster risk. Disaster cases in Palu City as a case study are considered relevant for the implementation of disaster management systems.

scholarly journals Spanning the gap: unraveling RSC dynamics in vivo

2021 ◽  
Author(s):  
Heinz Neumann ◽  
Bryan J. Wilkins
Keyword(s):  
Cell Cycle ◽  
Posttranslational Modifications ◽  
Transcriptional Activation ◽  
Binding Mode ◽  
Binding Modes ◽  
Binding Domains ◽  
Binding Interface ◽  
The Many ◽  
And Function

AbstractMultiple reports over the past 2 years have provided the first complete structural analyses for the essential yeast chromatin remodeler, RSC, providing elaborate molecular details for its engagement with the nucleosome. However, there still remain gaps in resolution, particularly within the many RSC subunits that harbor histone binding domains.Solving contacts at these interfaces is crucial because they are regulated by posttranslational modifications that control remodeler binding modes and function. Modifications are dynamic in nature often corresponding to transcriptional activation states and cell cycle stage, highlighting not only a need for enriched spatial resolution but also temporal understanding of remodeler engagement with the nucleosome. Our recent work sheds light on some of those gaps by exploring the binding interface between the RSC catalytic motor protein, Sth1, and the nucleosome, in the living nucleus. Using genetically encoded photo-activatable amino acids incorporated into histones of living yeast we are able to monitor the nucleosomal binding of RSC, emphasizing the regulatory roles of histone modifications in a spatiotemporal manner. We observe that RSC prefers to bind H2B SUMOylated nucleosomes in vivo and interacts with neighboring nucleosomes via H3K14ac. Additionally, we establish that RSC is constitutively bound to the nucleosome and is not ejected during mitotic chromatin compaction but alters its binding mode as it progresses through the cell cycle. Our data offer a renewed perspective on RSC mechanics under true physiological conditions.

THE CRITICALLY ILL CHILD: SICKLE CELL DISEASE CRISES AND THEIR MANAGEMENT

PEDIATRICS ◽  
1971 ◽  
Vol 48 (4) ◽  
pp. 629-635
Author(s):  
Howard A. Pearson ◽  
Louis K. Diamond
Keyword(s):  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Mutant Gene ◽  
Point Of View ◽  
Clinical Aspects ◽  
Cell Disease ◽  
Form And Function ◽  
Heterozygous Form ◽  
The Many ◽  
And Function

This brief review, being limited in scope to the recognition and management of the life-threatening and painful crises in infants and children with sickle-cell disease, has not even touched on the intriguing mystery of the molecular basis for the sickling phenomenon–how one amino-acid substitution (gene controlled) in the beta chain sequence of 146 amino acids can cause such serious disruption in form and function; or how this mutation occurred in the first place and why it has persisted in contrast to the rapid disappearance of many other deleterious mutants. Nor has there been even mention of the many milder symptoms, signs, and complications due to the presence of Hb. S., either in the homozygous (disease-producing) state or heterozygous form when found in combination with other hereditary hemoglobin defects. The accumulated knowledge about this mutant gene, its biochemical effects, and geographic distribution is enormous. From a fundamental scientific standpoint, sickle cell disease is one of the best understood of human afflictions. However, from a practical point of view treatment of the patient himself is often only symptomatic and palliative. Nevertheless, prompt and effective therapy of the myriad manifestations of sickle cell disease can effectively reduce morbidity and mortality. The pediatrician who cares for black children in his practice should be familiar with the cardinal diagnostic and clinical aspects of sickle cell disease and its crises.

scholarly journals The Preparedness Level of Families with Disabilities Children in Facing the Earthquake and Tsunami Disaster in Padang, West Sumatra

2021 ◽  
Vol 4 (1) ◽  
pp. 61
Author(s):  
Muchsin Riviwanto ◽  
Darwel Darwel ◽  
Defriani Dwiyanti ◽  
Juanda Juanda
Keyword(s):  
Disaster Preparedness ◽  
Local Governments ◽  
Statistical Tests ◽  
Disaster Mitigation ◽  
Special Treatment ◽  
Preparedness Plan ◽  
Tsunami Disaster ◽  
West Sumatra ◽  
The Face ◽  
Index Value

Disability groups are groups vulnerable to disaster risk. Most families with disabilities feel worried about defending themselves in the event of a disaster. They are less socialized with disaster mitigation efforts. This research has provided an overview of the preparedness of families with disabilities children in increasing disaster resilience. Analytical research was conducted on families with disabilities children in the city of Padang. Data collection tools in this study used a standard questionnaire from LIPI-UNESCO / ISDR. The data were processed by a computer and analyzed using multiple regression statistical tests. The results showed the preparedness of Families With Disabilities Children in the face of disasters; it was seen that the knowledge category was ready (42.2%), the preparedness plan category was not ready (37.8%), the disaster warning category was not ready (46.7%), the resource mobilization category was not ready, ready (82.2%), the tsunami disaster preparedness index value is 57% (ready category). This research recommended local governments must provide special treatment for people with disabilities by increasing training, seminars, and disaster simulations.

scholarly journals Estimation of Communities and Tourists Willingness to Pay for Tsunami Disaster Mitigation of Marine Tourism in the Kalianda Coastal Area, South Lampung Regency

2021 ◽  
Vol 19 (1) ◽  
pp. 1-9
Author(s):  
Permana Ari Soejarwo ◽  
Rismawaty Rusdi ◽  
Taryono Kodiran ◽  
Umi Muawanah
Keyword(s):  
Willingness To Pay ◽  
Contingent Valuation Method ◽  
Coastal Areas ◽  
Disaster Mitigation ◽  
Coastal Vegetation ◽  
Economic Losses ◽  
Coastal Protection ◽  
Tsunami Early Warning ◽  
Marine Tourism ◽  
Tsunami Disaster

Indonesia coastal areas have considerable natural disaster potential including in Kalianda District South Lampung Regency. Natural disasters such as earthquakes, tsunamis and volcanic activity are likely to occur in coastal areas. The disaster has an impact on economic losses in the marine tourism area. In order to mitigate tsunami disasters in the marine tourism area of Kalianda District, South Lampung Regency, 3 (three) types of tsunami mitigation are needed, namely: construction of coastal protection, installation of the Tsunami Early Warning System (TEWS) and planting of coastal vegetation. This study aims to determine the value of willingness to pay (WTP) of community and tourists in supporting the management of the three types of tsunami disaster mitigation above by using economic valuation / Contingent Valuation Method (CVM). The results of this study indicate that the WTP value of community for coastal protection management is Rp 15.547/person/month while the WTP value of tourist is Rp 12.030/one time entry. Meanwhile, for the WTP value of TEWS management is obtained Rp 12.174/person/month. WTP value for the management of coastal vegetation is Rp 12.444/person/month. The WTP calculation is based on consideration of 3 (three) factors, namely age, income, livelyhood and education level. This research shows that the community and tourists are willing to pay for the management of the three types of tsunami disaster mitigation through BUMDes and entrance fees for marine tourism area. The three types of tsunami disaster mitigation can protect, provide security and calm to the community and tourists in the marine tourism area of Kalianda District, South Lampung Regency from future tsunami.

The expanding world of metabolic enzymes moonlighting as RNA binding proteins

2021 ◽  
Author(s):  
Nicole J. Curtis ◽  
Constance J. Jeffery
Keyword(s):  
Gene Expression ◽  
Regulatory Networks ◽  
Binding Proteins ◽  
Molecular Mechanisms ◽  
Rna Binding ◽  
Rna Binding Proteins ◽  
Molecular Structures ◽  
Intermediary Metabolism ◽  
The Many ◽  
And Function

RNA binding proteins play key roles in many aspects of RNA metabolism and function, including splicing, transport, translation, localization, stability and degradation. Within the past few years, proteomics studies have identified dozens of enzymes in intermediary metabolism that bind to RNA. The wide occurrence and conservation of RNA binding ability across distant branches of the evolutionary tree suggest that these moonlighting enzymes are involved in connections between intermediary metabolism and gene expression that comprise far more extensive regulatory networks than previously thought. There are many outstanding questions about the molecular structures and mechanisms involved, the effects of these interactions on enzyme and RNA functions, and the factors that regulate the interactions. The effects on RNA function are likely to be wider than regulation of translation, and some enzyme–RNA interactions have been found to regulate the enzyme's catalytic activity. Several enzyme–RNA interactions have been shown to be affected by cellular factors that change under different intracellular and environmental conditions, including concentrations of substrates and cofactors. Understanding the molecular mechanisms involved in the interactions between the enzymes and RNA, the factors involved in regulation, and the effects of the enzyme–RNA interactions on both the enzyme and RNA functions will lead to a better understanding of the role of the many newly identified enzyme–RNA interactions in connecting intermediary metabolism and gene expression.

KAJIAN ORNAMEN GORGA DI RUMAH ADAT BATAK TOBA (Studi Kasus : Di Kawasan Desa Wisata Tomok, Huta Siallagan dan Huta Bolon Di Kabupaten Samosir)

2019 ◽  
Vol 2 (1) ◽  
pp. 1-14
Author(s):  
Dearma A Saragih ◽  
Yulianto Yulianto ◽  
Raimundus Pakpahan
Keyword(s):  
Comparative Research ◽  
Research Method ◽  
Toba Batak ◽  
Historical Heritage ◽  
The Many ◽  
Almost All ◽  
And Function ◽  
Meaning And Function ◽  
House Building

One of the interesting cultural potentials to be studied is traditional houses. This traditional house has its own uniqueness in every area. One of the uniqueness can be seen from the many ornaments in it. Diversity has its own meaning and function. Ornaments is one of the historical heritage of Indonesia where almost all the tribes in Indonesia can be found various kinds of ornaments that reflect the techniques of each region in Indonesia. Ornament Batak Toba is one of the many ornaments that exist in this country Indonesia. Toba Batak ornament can be found in North Sumatera Province precisely in Samosir regency which always apply Toba Batak ornament as decoration or as identity in important building for Batak Toba, for example in traditional house building in Huta Siallagan, Tomok Village and Huta Bolon.This research is classified in research using descriptive-comparative research method, doing the study by comparing the existing ornaments in these three villages with theories about Ornaments Gorga Rumah Adat Batak Toba, then do the analysis of the condition in accordance with the theory used as a reference

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