scholarly journals Aberrant promoter hypermethylation of RAR-β in endometrial carcinoma- an Indian study.

2021 ◽  
Vol 9 (3) ◽  
pp. 160-166
Author(s):  
Nagaratna Shivanandappa ◽  
◽  
Dr. Shalini N Swamy ◽  
Dr. Sandeep Kumar S ◽  
Dr. Suma Sheshadri ◽  
...  
Keyword(s):  
Endometrial Carcinoma ◽  
Methylation Status ◽  
Promoter Hypermethylation ◽  
P Value ◽  
Epigenetic Alterations ◽  
Gene Methylation ◽  
Chi Square ◽  
Diagnosis And Prognosis ◽  
Potential Marker ◽  
Chi Square Test

Endometrial cancer is the seventh most common cancer in women worldwide with an age-standardized rate of 8.4 per 100,000 women. Epigenetic alterations such as promoterhypermethylation of TSGs are known to be early events in carcinogenesis. The aim of the presentstudy, we assessed the aberrant promoter hypermethylation pattern of RAR-β in 78 endometrialcancer samples. Methods: DNA was isolated from endometrial carcinoma samples and normaltissues and aberrant promoter hypermethylation was assessed using nested and methylation-specificPCR. The Chi-square test was used for statistical analysis and a p-value<0.05 was considered to bestatistically significant. Results: 40 of the 78 (51.28%) endometrial carcinoma samples showedaberrant hypermethylation of the RAR-β gene. Methylation status in each histological subtype, gradeand stage of the disease was also assessed. Conclusion: Aberrant hypermethylation is an importantearly epigenetic alteration that occurs during tumorigenesis. The Data shown here reports thatpromoter hypermethylation of RAR-β occurs in endometrial carcinoma and therefore could be usedas a potential marker for early diagnosis and prognosis of the disease.

scholarly journals Assessment of Aberrant Promoter Hypermethylation of RASSF1a and P16 in Endometrial Carcinoma

2021 ◽  
Vol 8 (7) ◽  
pp. 402-409
Author(s):  
Nagaratna Shivanandappa ◽  
Shalini N Swamy ◽  
Sandeep Kumar S
Keyword(s):  
Endometrial Cancer ◽  
Endometrial Carcinoma ◽  
Promoter Hypermethylation ◽  
Pathological Examination ◽  
Clinicopathological Parameters ◽  
P Value ◽  
Dna Hypermethylation ◽  
Chi Square ◽  
Methylation Specific Pcr ◽  
Specific Pcr

Endometrial carcinoma is one of the most common gynecological malignancies known to affect around 142000 women worldwide. Aberrant promoter hypermethylation of tumor suppressor genes is a common epigenetic alteration reported in cancers. In the present study we report the aberrant promoter hypermethylation of RASSF1a and p16 in 78 endometrial cancer patients. Methods: Endometrial carcinoma samples were collected after pathological examination and DNA was extracted. The DNA was subjected to sodium bisulfite modification and then used to perform methylation specific PCR. The PCR was performed using a two step procedure of nested and methylation specific PCR. The PCR product was visualized using agarose gel electrophoresis. The results obtained were correlated with various clinicopathological parameters. Chi square test was used for statistical analysis and a p-value of <0.05 was considered statistically significant. Result: 60 of the 78 (76.92%) samples showed methylation for RASSF1a gene. 28 of the 78 (35.8%) samples showed methylation for p16 gene. A higher methylation frequency was observed for RASSF1a in the endometrioid and poorly differentiated histological subtypes and stage I and II of the disease. Conclusion: Aberrant promoter hypermethylation of RASSF1a and p16 is known to play an important role in endometrial cancer initiation and progression. The methylation patterns can be used as an important molecular marker for early diagnosis and prognosis of endometrial cancer. Keywords: Epigenetic alterations, DNA Hypermethylation, Endometrial cancer, RASSF1a, p16, Methylation-specific PCR.

Analisis Faktor Determinan Pelaksanaan Inisiasi Menyusu Dini Oleh Bidan Di Rumah Sakit Umum Anutapura Palu

2018 ◽  
Vol 1 (1) ◽  
pp. 34
Author(s):  
Ni Nyoman Novita ◽  
Gusman Arsyad
Keyword(s):  
Emergency Room ◽  
Peer Support ◽  
Statistical Tests ◽  
Bivariate Analysis ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Implementation Processes ◽  
Chi Square Test ◽  
The Government

Implementation of IMD in hospitals has decreased from the previous year and has not reached the target set by the government. Some IMD implementation processes have not been carried out according to applicable standards. So that babies do not get an IMD in accordance with existing SOPs. The purpose of this study was to determine the determinant factors associated with the implementation of the IMD by midwives in the Midwifery and Maternity Room Emergency Room (IGD) at the Anutapura General Hospital in Palu. This research method is analytical with cross sectional approach. The population of this study was that all midwives in the obstetrics emergency room and maternity room at Anutapura Palu Hospital were 37 respondents. The sample in this study is total sampling. The analysis used was univariate, and bivariate analysis using the chi square test with a confidence level of 95% (α = 0.05). The results of statistical tests on variable knowledge of midwives with the implementation of IMD p value: 0.018 (p value <0.05). APN training with the implementation of IMD p value: 0.697 (p value> 0.05). length of work with the implementation of IMD p value: 0.029 (p value <0.05). and peer support with the implementation of IMD p value: 0.007 (p value <0.05). Conclusions there is a relationship between knowledge, length of work, peer support with the implementation of the IMD, and training factors that have nothing to do with IMD implementation. The strongest factor in the relationship is peer support. It is recommended that the Anutarapura Palu Hospital be able to motivate midwives so that they can further enhance their role in the implementation and provide support to their colleagues so that the implementation of the IMD can be carried out in accordance with applicable standards.Keywords: Knowledge, APN Training, Duration of work, Implementation of IMD

HUBUNGAN ANTARA UMUR IBU DAN JARAK KEHAMILAN DENGAN KEJADIAN PERDARAHAN POSTPARTUM DI RUANG KEBIDANAN RSUD KOTA PRABUMULIH TAHUN 2016

2019 ◽  
Vol 7 (2) ◽  
Author(s):  
Desti Widya Astuti Desti Widya Astuti
Keyword(s):  
General Hospital ◽  
Post Partum ◽  
District General Hospital ◽  
Study Data ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Significance Level ◽  
Chi Square Test ◽  
Post Partum Bleeding

ABSTRAK   Berdasarkan data di RSUD Kota Prabumulih bahwa terdapat peningkatan jumlah kejadian perdarahan post partum, tahun 2014 sebanyak 178 orang, tahun 2015 sebanyak 246 orang dan tahun 2016 sebanyak 151 orang. Penelitian ini bertujuan untuk mengetahui hubungan umur ibu dan jarak kehamilan terhadap kejadian perdarahan post partum di RSUD Kota Prabumulih Tahun 2016. Penelitian ini merupakan penelitian analitik dengan rancangan cross sectional. Populasi yang digunakan adalah semua ibu bersalin di RSUD Kota Prabumulih, sebanyak 1.296 ibu bersalin dan 306 sampel. Pengambilan sampel dengan mengunakan random sampling, analisa data menggunakan analisa univariat dan bivariat dengan menggunakan uji statistik chi-square dengan derajat kemaknaan 0,05. Hasil penelitian ini menunjukan bahwa dari 288 ibu bersalin terdapat 151 yang mengalami perdarahan post partum sebagian besar adalah ibu dengan umur resiko tinggi sebanyak 43 orang  (40,9%) dan ibu dengan jarak kehamilan resiko tinggi sebanyak 21 orang (17,3%). Hasil uju chi-square umur didapatkan p.value 0,000 < α 0,05 dan uji chi-square untuk jarak kehamilan didapatkan p.value 0,000 < α 0,05. Maka ada hubungan umur ibu dan jarak kehamilan terhadap kejadian perdarahan post partum di RSUD Kota Prabumulih Tahun 2016. ABSTRACK   Based on the data at District General Hospital (RSUD) Prabumulih, there was increasing of post-partum bleeding, in 2014, there were 178 people. In 2015, there were 246 people. And in 2016, there were 151 people. The purpose of the study was to know relationship between maternal mother and the distance and old post-partum bleedingat District General Hospital (RSUD) Prabumulih in 2013. The study was analytic researchwith cross sectional design. Population thas was used in the study was all maternal mother ar District General Hospital (RSUD) Prabumulih. It was about 1.296 maternal mother and from 306. Random sampilng was done in the study, data analyses used univariate and bivariate analyses by using chi-square statistic test with significance level 0,05. The study result showed that from 306 maternal mother, there were 151 mother who experienced old post-partum bleeding, the large of that was high maternal mother 43 people  (40,9%) and mother age high distance 21 people (17,3%). The result of chi-square test was p value 0,000 < α 0,05 and chi-square test for age was p value 0,000 < α 0,05. It meant that there was relationship between maternal mother and the distance and of post-partum bleeding at District General Hospital (RSUD) Prabumulih in 2016.

HUBUNGAN UMUR DAN PARITAS IBU DENGAN KEJADIAN HIPEREMESIS GRAVIDARUM DI RUMAH SAKIT UMUM PUSAT Dr. MOHAMMAD HOESIN PALEMBANG TAHUN 2011

2019 ◽  
Vol 2 (1) ◽  
Author(s):  
Wahyu Ida Muliana Wahyu Ida Muliana
Keyword(s):  
Pregnant Women ◽  
Medical Record ◽  
Random Sampling ◽  
Hyperemesis Gravidarum ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Systematic Random Sampling ◽  
Pregnancy And Childbirth ◽  
Chi Square Test

ABSTRACT Hyperemesis Gravidarum marked excessive nausea and vomiting in pregnant women at a young age. WHO estimates that 536,000 women died from direct complications of pregnancy and childbirth. One complication of pregnancy is Hyperemesis Gravidarum. Hyperemesis Gravidarum in the world has been estimated to occur in 1-2% of pregnant. According to data from the Medical Record of Dr. Mohammad Hoesin Palembang Hospital, the incidence of Hyperemesis Gravidarum in 2011 there were 72 people of 661 pregnant women. The purpose of this reseach was to determine the relationship between maternal age and parity with Hyperemesis Gravidarum in Dr. Mohammad Hoesin Palembang Hospital 2011. The Design of this reseach used Cross Sectional by analytic approach survey. The population of this reseach are all of mother who gestational ≤ 16 weeks (four months) in the Installation of Obstetrics and Gynecology, Dr. Mohammad Hoesin Palembang Hospital in January to December of 2011 with the sample of 661 people which taken by systematic random sampling and the reseach was conducted from 17 April to 24 April 2012.  Each variable that was observed in tests using Chi-Square test with a (0.05).  The results of this study showed that 5.9% of mothers with hyperemesis gravidarum, 21.8% of mothers with high risk age, and 30.0% primigravida. Chi-Square test showed no significant relationship between age (p value = 0.000) and parity (p value = 0.000) with the incidence of hyperemesis gravidarum. Expected to the Hospital to be implemented properly instructed how to provide counseling to pregnant women about pregnancy and childbirth, as well as provide confidence that the nausea and vomiting is a symptom of physiology in pregnancy.   ABSTRAK Hiperemesis Gravidarum ditandai mual dan muntah yang berlebihan terjadi pada ibu hamil di usia muda. WHO memperkirakan 536.000 perempuan meninggal dunia akibat langsung dari komplikasi kehamilan dan persalinan. Salah satu komplikasi kehamilan adalah Hiperemesis Gravidarum. Insiden Hiperemesis Gravidarum di dunia telah diperkirakan terjadi pada 1-2% wanita hamil. Menurut data dari Medical Record Rumah Sakit Umum Pusat Dr. Mohammad Hoesin Palembang, angka kejadian Hiperemesis Gravidarum pada tahun 2011 terdapat 72 orang dari 661 ibu hamil. Tujuan penelitian ini adalah untuk mengetahui hubungan antara umur dan paritas ibu dengan kejadian Hiperemesis Gravidarum pada ibu di Rumah Sakit Umum Pusat Dr. Mohammad Hoesin Palembang tahun 2011. Desain Penelitian ini menggunakan survei analitik dengan pendekatan Cross Sectional. Populasi penelitian ini adalah dengan umur kehamilan ≤ 16 minggu (4 bulan) yang pernah dirawat inap di Instalasi Kebidanan dan Penyakit Kandungan Rumah Sakit Umum Pusat Dr. Mohammad Hoesin Palembang pada bulan Januari-Desember tahun 2011 dengan jumlah sample 661 orang yang diambil secara systematic Random Sampling (secara acak sistematis) dan penelitian ini dilakukan dari tanggal 17 April sampai dengan 24 April 2012. Masing-masing variabel yang diteliti di uji dengan menggunakan uji Chi-Square dengan a (0,05). Hasil penelitian ini menunjukkan bahwa 5,9% ibu mengalami hiperemesis gravidarum, 21,8% ibu dengan umur resiko tinggi, dan 30,0% ibu primigravida. Uji Chi-Square menunjukkan ada hubungan yang bermakna antara umur (p value = 0,000) dan paritas (p value = 0,000) dengan kejadian hiperemesis gravidarum. Diharapkan dapat menjadi masukan bagi pihak Rumah Sakit agar dilaksanakan penyuluhan dengan cara memberikan konseling terhadap ibu hamil tentang kehamilan dan persalinan, serta memberikan keyakinan bahwa mual muntah merupakan gejala fisiologi pada kehamilan.

Hubungan Pola Asuh Orang Tua Terhadap Perkembangan Sosial Anak Usia 4-6 Tahun Di Tk Dharma Wanita Gumukmas Tahun 2011

2012 ◽  
Vol 1 (2) ◽  
Author(s):  
Wahyu Widayati
Keyword(s):  
P Value ◽  
Chi Square ◽  
Chi Square Test

Pola asuh orang tua adalah pola perilaku yang diterapkan pada anak dan bersifat relative konsisten dari waktu ke waktu. Dimana salah satu faktor yang mempengaruhi perkembangan sosial anak adalah cara mendidik anak dalam keluarga (pola asuh). Penelitian ini bertujuan untuk mengetahui hubungan pola asuh orang tua terhadap perkembangan sosial anak usia 4-6 tahun di TK Dharma wanita Gumukmas Tahun 2011. Desain penelitian yang digunakan adalah penelitian deskriptif korelasi dengan populasi orang tua murid di TK Dharma wanita Gumukmas. Pengambilan sampel dengan total sampling sebanyak 95 responden. Pengumpulan data untuk mengetahui pola asuh oang tua dan perkembangan sosial anak dengan menggunakan koesioner. Analisanya yaitu univariat dan bivariat. Uji statistik yang digunakan chi square test dengan derajat kemaknaan p>0,05. Hasil penelitian menunjukkan bahwa tidak ada hubungan yang bermakna antara pola asuh orang tua dengan perkembangan sosial anak usia 4-6 tahun di TK Dharma wanita Gumukmas dengan p value 0,008. Berdasarkan hasil penelitian tersebut, diharapkan perlunya pemahaman tentang metode pemberian pola asuh yang efektif bagi anak karena ini sangat penting untuk perkembangan sosial anak

Hubungan Status Gizi Dengan Proses Penyembuhan Luka Di Rsud H. Andi Sulthan Daeng Radja Kabupaten Bulukumba

2017 ◽  
Vol 2 (1) ◽  
pp. 20-28
Author(s):  
Fitriani ◽  
Tenriwati
Keyword(s):  
Wound Healing ◽  
Nutritional Status ◽  
Healing Process ◽  
Data Retrieval ◽  
Observational Research ◽  
Wound Healing Process ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Chi Square Test

At present, the incidence of injuries in Indonesia is quite high, as seen from data on traffic accidents in the general public. There are several factors that affect wound healing, one of which is nutritional status. Based on the preliminary data retrieval conducted by researchers in the seruni surgery room in the last 1 month namely in March, it was found that the number of wounded patients was 109 patients, where the number of men was 78 (71.56%) while the number of women was 31 ( 28.44%) The purpose of this study was to determine the relationship between nutritional status and the wound healing process in RSUD. H. Andi. Sulthan Daeng Radja Kab. Bulukumba. This research uses the type of design of this research is quantitative research. This type of research uses analytic observational research with cross sectional approach. The sample of this study were 41 respondents taken by purposive sampling method. Data analysis in this study used the chi-square test (chi square test). The results of the analysis used the chi-square statistical test with a confidence level (α = 0.05). Based on the results of this test, the p value is 0.001, thus p <α (0.001 <0.05), then Ho is rejected and Ha is accepted. The conclusion of this study is that there is a relationship between nutritional status and the process of wound healing in RSUD. H. Andi. Sulthan Daeng Radja Kab. Bulukumba. Researchers suggest that this study be used as a material consideration in the fulfillment of nutrition in wound care patients in RSUD.H.A. Sulthan Daeng Radja Kab. Bulukumba and this research can be continued by conducting research related to the wound healing process and linking it with other variables.

Relationship of Workload and Double Role With Work Fatigue on Batik Craftsmen

2019 ◽  
Vol 4 (2) ◽  
pp. 293
Author(s):  
Herdianti Herdianti ◽  
Tatik Maryana
Keyword(s):  
Data Analysis ◽  
Quantitative Research ◽  
Sampling Technique ◽  
Work Load ◽  
Dual Role ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Chi Square Test ◽  
Almost All

<p><em><em>Background: In Batik Mawar, almost all work is done manually using the hands and upper arms on a continuous basis combined with the rigor of work and the use of traditional tools. The work has a heavy workload because all the work process is done by the same craftsman causing fatigue besides that the worker also have double role. The purpose of this study is to determine the relationship between workload and dual role with feelings of fatigue on craftsmen batik roses.Method: This research is Quantitative research with Cross Sectional research design. The population in this study are all artisans in Batik Mawar. Sampling in this study using total sampling technique with the number of research samples as many as 40 respondents. Data analysis used by Univariat and Bivariat.Result: Result of data analysis using Chi-Square test for work load got value p-Value = 0,001. The result of data analysis using Chi-square test for double role got p-value = 0,031. Thus it is concluded that there is a meaningful relationship between workload and dual role with feeling tired. We recommend that craftsmen wash clothes 2 times a day, cook ready meals, other than together in completing the work at home</em></em></p><p><em><br /></em></p><p><em>Di Batik Mawar, hampir semua pekerjaan dikerjakan secara manual menggunakan tangan dan lengan atas secara berkesinambungan yang dikombinasi dengan ketelitian kerja dan penggunaan alat-alat tradisional. Pekerjaan mempunyai beban kerja yang berat dikarenakan semua proses kerja dilakukan oleh pengrajin yang sama sehingga menimbulkan kelelahan</em><em> disamping itu pekerjanya juga memiliki peran ganda</em><em>.</em><em> Tujuan penelitian ini adalah untuk mengetahui hubungan beban kerja dan peran ganda dengan perasaan lelah pada pengrajin batik mawar.Metode: </em><em>Penelitian ini merupakan penelitian Kuantitatif dengan desain penelitian Cross Sectional. Populasi dalam penelitian ini adalah semua pengrajin di Batik Mawar. Pengambilan sampel pada penelitian ini menggunakan teknik total sampling dengan jumlah sampel penelitian sebanyak 40 responden. Analisis data yang digunakan Univariat dan Bivariat.</em><em>Hasil: </em><em>Hasil analisis data yang menggunakan uji Chi-Square untuk beban kerja didapatkan nilai p-Value = 0,001. Hasil analisis data yang menggunakan uji Chi-square untuk peran ganda didapatkan nilai p-value= 0,031. Dengan demikian  disimpulkan bahwa ada hubungan yang bermakna antara beban kerja dan peran ganda dengan perasaan lelah.Sebaiknya pengrajin mencuci pakaian 2 kali sehari, memasak makanan siap saji, selain itu dengan cara bersama-sama dalam menyelesaikan pekerjaan dirumah.</em><em></em></p><strong><em></em></strong>

Relationship of Fiber Intake, Stress Level, Physical Activity with Blood Pressure of Pre Elderly and Elderly in Lubang Buaya and Kampung Tengah

2021 ◽  
Vol 1 (1) ◽  
pp. 1
Author(s):  
Eti Cahya Fitrianti ◽  
Sintha Fransiske Simanungkalit
Keyword(s):  
Physical Activity ◽  
Blood Pressure ◽  
Stress Level ◽  
Blood Pressure Measurement ◽  
Bivariate Analysis ◽  
P Value ◽  
Fiber Intake ◽  
Chi Square ◽  
Stress Levels ◽  
Chi Square Test

High blood pressure is defined as systolic blood pressure that is equal to or above 140 mm Hg or diastolic blood pressure equal to or above 90 mm Hg (JNC VIII, 2013). In 2018, the prevalence of hypertension in Indonesia is based on the characteristics of the age 45-75 years and above with an average of 58.33% (Riskesdas, 2018). The aimed of this study was to determine of fiber intake, stress levels, and physical activity with blood pressure in pre elderly and elderly at RW 03 Lubang Buaya and RW 09 Kampung Tengah, East Jakarta. This research method is observational with cross sectional approach followed by 80 respondents with simple random sampling technique Data collection was taken, namely blood pressure measurement using a Sphygmomanometer, fiber intake using the Food Recall form 2 x 24 hours (Weekend and Weekday), stress levels with the DASS-14 questionnaire, and physical activity with the Baecke questionnaire. Data processing was analyzed by univariate and bivariate using Chi-Square test. The results of bivariate analysis with chi-square test showed a significant relationship between fiber intake (p value = 0.007), stress level (p value = 0,000), and physical activity (p value = 0.022) with blood pressure. There is a relationship between fiber intake, stress level, and physical activity with blood pressure in the elderly and elderly in Lubang Buaya and Kampung Tengah.

Evaluation of Quality of Root Canal Obturation, Coronal Restoration and Periapical Health in Failed Endodontically Treated Teeth

2021 ◽  
Vol 11 (02) ◽  
pp. 54-59
Author(s):  
Syed Adeel Ahmed ◽  
Safia Anwar ◽  
Imtiaz ul Haq
Keyword(s):  
Root Canal ◽  
P Value ◽  
Periapical Lesion ◽  
Endodontically Treated Teeth ◽  
Chi Square ◽  
Cross Sectional ◽  
Total N ◽  
Chi Square Test ◽  
Cross Tabulation

Objective: To investigate the implication of quality of obturation and coronal restoration on periapical tissue in failed endodontically treated teeth. Study Design and Setting: This cross-sectional research was performed in the Operative Department of BUMDC on 187 patients reporting with root canal failure from March 2019 to August 2019. Methodology: Patients of both genders aged between 20-60 years were considered for this study. Single and multirooted teeth indicated for repeated endodontic treatment due to under filled, overfilled obturation, voids in obturation, absence and presence of coronal restoration were included. One operator carried out clinical examination of the teeth and periapical radiograph was taken for each patient by using E-Speed film and evaluated by the same operator using an illuminated viewer box. SPSS 17 for windows software was used for data entering and chi- square test was applied for statistical calculation of the outcomes. Results: Total n=187 endodontic treated failed teeth were evaluated, out of which 52.9% were of females and 47.1% to males. The number of obturations with acceptable length were 81(43.3%), with adequate density were 107 (57.2%) and with consistent taper were 116(62%). Periapical lesion was observed in 118(63.1%) cases. Quality of obturation significantly affects the periapical health. Cross tabulation showed a significant association (p-value <0.000) between inadequate coronal restoration and changes in periapical area. Conclusion: The successful prognosis of the root canal treatment relies on the good quality of obturation and adequate coronal filling.

HUBUNGAN TINGKAT PENGETAHUAN MENGENAI DIET HIPERTENSI TERHADAP KEJADIAN HIPERTENSI PADA LANSIA DI PUSKESMAS BALOI PERMAI BATAM KOTA

2020 ◽  
Vol 9 (1) ◽  
pp. 50-60
Author(s):  
Brain Guntoro ◽  
Kasih Purwati
Keyword(s):  
Public Health ◽  
Health Center ◽  
The Elderly ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Public Health Center ◽  
Chi Square Test ◽  
History Of ◽  
Level Of Knowledge

Hypertension is one of the number one causes of death and disability in the world. Hypertension contributes nearly 9.4 million deaths from cardiovascular disease each year. Hypertension can cause undesirable effects, it needs good handling, one of them is by doing a hypertension diet. To carry out a hypertension diet requires knowledge, lack of knowledge can increase risk factors for hypertension. This study aims to determine the relationship of the level of knowledge about hypertension diet to the incidence of hypertension in the elderly at the Baloi Permai Public Health Center Batam City. This research method is an analytic observational with a cross-sectional approach conducted at the Baloi Permai Public Health Center Batam City 2018. Sampling technique is a total sampling with a sample of 64 people in 2018 determined by inclusion and exclusion criteria. The results of the study were analyzed with frequency distribution and then tested with the Chi-square test. Based on the results of this study indicate that of the 64 respondents found elderly who have a good level of knowledge are 41 people (64.1%), 48 people (75.0%) have an age range between 60-70 years. 27 people (42.2%) elderly have the last high school education and 40 people (62.5%) have jobs as entrepreneurs. Elderly people who have normal blood pressure are 40 people (62.5%), and those affected by hypertension are 24 people (37.5%). The elderly who have a family history of hypertension is 21 people (32.8%) and those who do not have a history of hypertension are 43 people (67.2%). Chi-Square Test analysis results show the significance value p = 0.009. This number is significant because the p-value is smaller than the significance level (α) ≤ 5% (0.05), so H0 is rejected and Ha is accepted. Therefore it can be concluded that there is a significant relationship about the level of knowledge about the hypertension diet to the incidence of hypertension in the elderly. From the results of this study it was concluded that there was a relationship between the level of knowledge about the hypertension diet and the incidence of hypertension in the elderly at the Baloi Permai Public Health Center Batam City in 2016.

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