scholarly journals Effect of vitamin D intake on quality of life parameters in office workers

2021 ◽  
Vol 14 (2) ◽  
pp. 180-189
Author(s):  
A. T. Sharman ◽  
Sh. K. Adambekov ◽  
A. A. Imandosova ◽  
G. F. Elemesova
Keyword(s):  
Quality Of Life ◽  
Vitamin D ◽  
Blood Serum ◽  
Vitamin D Deficiency ◽  
Vitamin D Supplementation ◽  
Office Workers ◽  
Psychological Status ◽  
Sf 36 ◽  
Before And After

Objective: to study the prevalence of vitamin D deficiency and analyze the results of therapy in office workers, including an assessment of the quality of life.Material and methods. An observational non-interventional cross-sectional, cohort, prospective phase IV clinical study included office workers (151 people, age 18–44 years), who were prescribed an aqueous solution of vitamin D. The concentration of 25(OH)D in the blood of patients was measured before and after undergoing treatment. The duration of therapy, depending on the degree of deficiency, was 4 or 8 weeks. The SF-36 scale was used to assess the physiological and psychological status.Results. In 75.5% of the study participants, a insufficiency or deficiency of vitamin D was detected. Differences in the average content of 25(OH)D in blood serum before and after treatment with vitamin D were statistically significant. The level of vitamin D in blood serum, measured by the content of its metabolite 25(OH)D <30 ng/ml, is regarded as suboptimal, i.e. its insufficiency occurs, and <20 ng/ml – as vitamin D deficiency (p<0.0001). The SF-36 score showed significant statistically significant improvements in overall health, physical functioning, and pain in individuals with vitamin D deficiency after vitamin D supplementation. The use of multiple linear regression demonstrated an association of serum 25(OH)D levels with vitamin D-rich foods taken less than once a week.Conclusions. Vitamin D deficiency is very common among office workers: 75.5% had D 25(OH)D levels below 30 ng/ml. Vitamin D deficiency is corrected by taking this vitamin. Vitamin D supplementation helps to improve physical and mental health indicators. Serum 25(ОН)D levels are associated with intake of vitamin D-rich foods and duration of vitamin D treatment.

scholarly journals THE ROLE OF VITAMIN D SUPPLEMENTATION FOR HEAD AND NECK CANCER : A LITERATURE REVIEW

2019 ◽  
Vol 6 (1) ◽  
pp. 59
Author(s):  
Dewi Kania Intan Permatasari ◽  
Irna Sufiawati
Keyword(s):  
Quality Of Life ◽  
Vitamin D ◽  
Head And Neck Cancer ◽  
Literature Review ◽  
Head And Neck ◽  
Vitamin D Deficiency ◽  
Neck Cancer ◽  
Active Form ◽  
Vitamin D Supplementation

Background: Vitamin D has several roles, namely physiological function of calcium and bone metabolism, cell growth and differentiation, immune and cardiovascular function. Vitamin D deficiency can cause the risk of cancer. Head and neck cancer is one of the cancers that occur due to vitamin D deficiency in the body. This literature review was to asses and evaluate the impact and benefits of vitamin D supplementation for head and neck cancer.Discussion: A study found an association between vitamin D supplementation and a low risk of recurrence in conditions of high total vitamin D levels. Another study found a significant increase in quality of life (QOL). The primary mechanism of vitamin D action is mediated through binding of either 1,25(OH)2D3 (active form) or 25(OH)D (less active form) to the VDR, which is a member of the nuclear receptor superfamily of steroid and thyroid hormones with gene-regulatory and consequent anti-proliferative properties.Conclusions: Vitamin D supplementation provides a role in improving the condition of patients with head and neck cancer. Both in terms of suppressing recurrence and in terms of increasing quality of life

Effect of vitamin D supplementation on asthma control in patients with vitamin D deficiency: the ACVID randomised clinical trial

Thorax ◽  
2020 ◽  
pp. thoraxjnl-2019-213936
Author(s):  
Rubén Andújar-Espinosa ◽  
Lourdes Salinero-González ◽  
Fátima Illán-Gómez ◽  
Manuel Castilla-Martínez ◽  
Chunshao Hu-Yang ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Asthma Control ◽  
Intervention Group ◽  
Vitamin D Supplementation ◽  
Control Group ◽  
Asthmatic Patients ◽  
Secondary Endpoints

BackgroundThe relationship between asthma and vitamin D deficiency has been known for some time. However, interventional studies conducted in this regard have shown conflicting results.ObjectiveTo evaluate the efficacy of vitamin D supplementation in asthmatic patients in improving the degree of control of asthma.MethodsRandomised, triple-blind, placebo-controlled, parallel-group study in adult asthmatic patients with serum 25-hydroxyvitamin-D3 <30 ng/mL. The intervention group received oral supplementation with 16 000 IU of calcifediol per week, and the control group had placebo added to their usual asthma treatment. The study period was 6 months. The primary endpoint was the degree of asthma control as determined by the asthma control test (ACT). Secondary endpoints included quality of life measured using the mini Asthma Quality of Life Questionnaire, the number of asthma attacks, oral corticosteroid cycles, the dose of inhaled corticosteroids, number of emergency visits, unscheduled consultations with the primary care physician and hospitalisations for asthma.ResultsOne hundred and twelve patients were randomised (mean age 55 years, with 87 (78%) being women). Of the 112 patients, 106 (95%) completed the trial. Half the patients (56) were assigned to the intervention group and the other half to the control group. A statistically significant clinical improvement was observed in the intervention group (+3.09) compared with the control group (−0.57) (difference 3.66 (95% CI 0.89 to 5.43); p<0.001) as measured using ACT scores. Among the secondary endpoints, a significant improvement in the quality of life was found in the intervention group (5.34), compared with the control group (4.64) (difference 0.7 (95% CI 0.15 to 1.25); p=0.01).ConclusionAmong adults with asthma and vitamin D deficiency, supplementation with weekly oral calcifediol compared with placebo improved asthma control over 6 months. Further research is needed to assess long-term efficacy and safety.Trial registration numberNCT02805907.

Effects of Vitamin D Supplementation on Nonspecific Musculoskeletal Pain, Quality of Life, Self-Related Health and Sexual Satisfaction: A Randomized Control Trial

2018 ◽  
Vol 17 (1) ◽  
pp. 17-22
Author(s):  
Mottaghi Peyman ◽  
Miraghajani Maryam ◽  
Hajianfar Hossein ◽  
Abadi Rayehe Shekl
Keyword(s):  
Quality Of Life ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Sexual Satisfaction ◽  
Intervention Group ◽  
Vitamin D Supplementation ◽  
Unknown Etiology ◽  
Self Rated Health ◽  
Pain Scores

Non-specific musculoskeletal pains (CNMP) are common problem with unknown etiology which has become a major concern because of their negative impact on health. The aim of the present study was to investigate the effect of vitamin D supplementation on pain scores, quality of life, self-rated health and sexual satisfaction among CNMP patients with vitamin D deficiency. In this clinical trial study, sixty-six patients (18–50 years in both sex) with CNMP and vitamin D deficiency were randomly assigned to consume 50000 IU vitamin D, once every week for 8 weeks in the intervention group or placebo in the control condition. Clinical examination, pain scores, quality of life (QoL), self-rated health and sexual satisfaction were measured at the beginning and at the end of study. Patients in the vitamin D group had a significant pain relief after 8 weeks compared to the placebo group (p = 0.04 vs. p = 0.42). Also, they had increased QoL scores and sexual satisfaction compared with placebo (p < 0.0001 and p = 0.01, respectively). We observed a significant effect on improvement of quality of life, sexual satisfaction and pain in patients with CNMP after administration of therapeutic doses of vitamin D. Such findings could be considered to implement informative interventional programs to control CNMP complications and develop practical policies to improve the diet quality among CNMP patients. Further studies are needed to determine whether vitamin D supplementation lead to significant modifications in CNMP complications with consideration of confounding factors in different population.

PREVENTION OF COGNITIVE DISORDERS IN ELDERLY AND SENILE PATIENTS

2021 ◽  
pp. 721-726
Author(s):  
Г.И. Шварцман ◽  
Е.М. Первова ◽  
С.В. Лобзин ◽  
Е.Г. Клочева ◽  
В.В. Голдобин ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Vitamin D ◽  
Cerebrovascular Disease ◽  
Blood Serum ◽  
Cognitive Functions ◽  
Cognitive Disorders ◽  
Vitamin D Levels ◽  
Sf 36 ◽  
Low Levels

Целью исследования была оценка влияния витамина D на когнитивные функции и качество жизни пациентов пожилого и старческого возраста с цереброваскулярной болезнью. Обследованы 100 пациентов пожилого и старческого возраста с цереброваскулярной болезнью: у 60 человек уровень 25(OH)D в сыворотке крови <20 нг/мл (дефицит, выраженный дефицит), у 40 человек данный показатель был ≥30 нг/мл (в пределах нормы). Когнитивные функции оценивали по нейропсихологическим шкалам MMSE, MoCA, FAB, тесту «рисование часов», таблицам Шульте. Для исследования качества жизни все пациенты заполняли общий опросник SF-36. Об обеспеченности организма витамином D судили по содержанию 25(OH)D в сыворотке крови. Пациенты с низким уровнем витамина D [25(ОН)D <20 нг/мл] были разделены на две подгруппы: 1-я - 30 человек, которым холекальциферол назначили в дозировке 8 000 МЕ/сут в течение 3 мес; 2-я - 30 человек, которым терапию холекальциферолом не проводили. Исследование показало, что пациенты с низким уровнем витамина D [25(OH)D <20 нг/мл] имели достоверно значимо ниже показатели как когнитивных функций, так и качества жизни. В работе было доказано, что когнитивные функции влияют на качество жизни. У пациентов с исходно низким уровнем витамина D [25(ОН)D <20 нг/мл] после приема холекальциферола в дозировке 8 000 МЕ/сут в течение 3 мес наблюдали нормализацию уровня 25(ОН)D (средний уровень составил 34,10±7,42 нг/мл) в сыворотке крови и отмечали достоверно значимую положительную динамику при оценке когнитивных функций и качества жизни. The aim of the study was to evaluate the effect of vitamin D on the cognitive functions and quality of life in elderly and senile patients with cerebrovascular disease. 100 elderly and senile patients with cerebrovascular disease were examined: 60 people - level 25 (OH)D in blood serum <20 ng/ml (deficiency, pronounced deficiency), in 40 people this indicator was ≥30 ng/ml (within the normal range). Cognitive functions were evaluated according to neuropsychological scales (MMSE, MoCA, FAB, «clock drawing test», Schulte tables). To study the quality of life, all patients filled out a general questionnaire SF-36. The body’s vitamin D supply was judged by the content of 25 (OH)D in the blood serum. Patients with low vitamin D levels (25 (OH)D <20 ng / ml) were divided into two subgroups: 30 people were prescribed cholecalciferol at a dosage of 8 000 IU/day for three months and 30 people who were not treated with cholecalciferol. The study showed that patients with low levels of vitamin D [25 (OH)D <20 ng/ml] had significantly worse indicators when assessing both cognitive functions and quality of life. The work proved that cognitive functions affect the quality of life. In patients with extremely low levels of vitamin D [25 (OH)D <20 ng/ml], after taking cholecalciferol at a dosage of 8000 IU/day for three months, there was a normalization of the level of 25 (OH)D (the average level of which was 34,10±7,42 ng/ml) in the blood serum and there was a significantly significant positive dynamics in assessing cognitive functions and quality of life.

scholarly journals The sensitivity to change of the cluster headache quality of life scale assessed before and after deep brain stimulation of the ventral tegmental area

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Davide Cappon ◽  
Agata Ryterska ◽  
Harith Akram ◽  
Susie Lagrata ◽  
Sanjay Cheema ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cluster Headache ◽  
Mcgill Pain Questionnaire ◽  
Sensitivity To Change ◽  
Sf 36 ◽  
Quality Of Life Scale ◽  
Before And After ◽  
Life Scale ◽  
Generic Measures

Abstract Background Cluster headache (CH) is a trigeminal autonomic cephalalgia (TAC) characterized by a highly disabling headache that negatively impacts quality of life and causes limitations in daily functioning as well as social functioning and family life. Since specific measures to assess the quality of life (QoL) in TACs are lacking, we recently developed and validated the cluster headache quality of life scale (CH-QoL). The sensitivity of CH-QoL to change after a medical intervention has not been evaluated yet. Methods This study aimed to test the sensitivity to change of the CH-QoL in CH. Specifically we aimed to (i) assess the sensitivity of CH-QoL to change before and following deep brain stimulation of the ventral tegmental area (VTA-DBS), (ii) evaluate the relationship of changes on CH-QoL with changes in other generic measures of quality of life, as well as indices of mood and pain. Ten consecutive CH patients completed the CH-QoL and underwent neuropsychological assessment before and after VTA-DBS. The patients were evaluated on headache frequency, severity, and load (HAL) as well as on tests of generic quality of life (Short Form-36 (SF-36)), mood (Beck Depression Inventory, Hospital Anxiety and Depression Rating Scale), and pain (McGill Pain Questionnaire, Headache Impact Test, Pain Behaviour Checklist). Results The CH-QoL total score was significantly reduced after compared to before VTA-DBS. Changes in the CH-QoL total score correlated significantly and negatively with changes in HAL, the SF-36, and positively and significantly with depression and the evaluative domain on the McGill Pain Questionnaire. Conclusions Our findings demonstrate that changes after VTA-DBS in CH-QoL total scores are associated with the reduction of frequency, duration, and severity of headache attacks after surgery. Moreover, post VTA-DBS improvement in CH-QoL scores is associated with an amelioration in quality of life assessed with generic measures, a reduction of depressive symptoms, and evaluative pain experience after VTA-DBS. These results support the sensitivity to change of the CH-QoL and further demonstrate the validity and applicability of CH-QoL as a disease specific measure of quality of life for CH.

scholarly journals A functional electric orthesis on the paretic leg improves quality of life of stroke patients

2006 ◽  
Vol 64 (1) ◽  
pp. 20-23 ◽  
Author(s):  
Mara Renata Fernandes ◽  
Luciane B.C. Carvalho ◽  
Gilmar F. Prado
Keyword(s):  
Quality Of Life ◽  
Social Functioning ◽  
Physical Functioning ◽  
Bodily Pain ◽  
Improve Quality ◽  
Stroke Patients ◽  
Normal Life ◽  
Sf 36 ◽  
Before And After

CONTEXT: Hemiparesia changes quality of life of patients with stroke making difficult a normal life. OBJECTIVE: To evaluate the effect of Functional Eletric Orthesis (FEO) applied over the paretic leg in the quality of life of stroke patients. METHOD: The quality of life of 50 stroke patients of Associacao de Assistencia a Crianca Deficiente (AACD) was evaluated with SF-36 questionnaire before and after the treatment with a FEO for rehabilitation of walking. We analyzed data according to gender and affected hemisphere. RESULTS: The average values from all domains of SF-36 improved significantly (p<0.001). Female patients improved more than male in Emotional Domain (p=0.04) and presented a trend to be better regarding Bodily Pain and Social Functioning. Patients with right hemiparesia improved more than those with left hemiparesia (p=0.02). CONCLUSION: FEO over a paretic leg is efficient to improve quality of life of stroke patients, mainly Physical Functioning.

The effects of breathing exercises on respiratory functions, functional capacity and quality of life in vehicle spray painters

2021 ◽  
Vol 28 (12) ◽  
pp. 1-8
Author(s):  
Burak Yilmaz ◽  
Cagtay Maden ◽  
Begümhan Turhan
Keyword(s):  
Quality Of Life ◽  
Functional Capacity ◽  
Control Group ◽  
Study Group ◽  
Breathing Exercises ◽  
Sf 36 ◽  
Significant Difference ◽  
Before And After ◽  
Respiratory Exercises

Background/aims Workers engaged in vehicle spray painting are at a risk of developing respiratory problems because of the solvents in the spray paints. Changes in respiratory functions and functional capacities caused by spray painting can be improved with respiratory exercises. The aim of this study was to examine the effects of respiratory exercises on the respiratory functions, functional capacity and quality of life in vehicle spray painters. Methods A total of 70 volunteers with similar characteristics participated in the study. The groups were divided into two groups randomly (35 study group, 35 control group). Respiratory functions (value of forced expiratory volume percentage in 1 second [FEV1]), forced vital capacity percentage [FVC], FEV1/FVC percentage, peak expiratory flow percentage [PEF (%)] and maximum voluntary ventilation percentage [MVV (%)]), functional capacity (6-Minute Walk Test) and quality of life (Short Form Health Survey [SF-36]) were evaluated. The study group undertook supervised breathing exercises 3 days a week for 6 weeks. The same exercises were given to the control group as a home programme. Home programmes were followed up by telephone calls. Evaluations were performed again after 6 weeks. Results In the study group, FEV1 (%) increased more than in the control group (P<0.05). The increase in PEF (%) was similar in both groups (P>0.05). In the study group, FEV1/FVC (%) and MVV (%) were significantly different before and after the intervention (P<0.05), but there was no difference in the control group (P>0.05). There was a greater increase in the study group than in the control group (P<0.05). 6-Minute Walk Test distance (m) before and after the intervention in both groups were similar (P>0.05). Before and after the intervention, a significant difference was found in the vitality and the social function domains of the SF-36 in the study group. In the comparisons of groups, a significant difference was found in the study group in the role-emotional, social function and bodily pain domains of the SF-36 after the intervention (P<0.05). Conclusions Breathing exercises can be recommended for vehicle spray painters to avoid an increase in respiratory resistance and to improve their quality of life.

scholarly journals Analysis of risk factors for vitamin D deficiency by results of the first stage of Russian non-interventional register study

2021 ◽  
pp. 109-118
Author(s):  
L. A. Suplotova ◽  
V. A. Avdeeva ◽  
L. Y. Rozhinskaya ◽  
E. A. Pigarova ◽  
E. A. Troshina
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Russian Federation ◽  
Direct Sunlight ◽  
Cross Sectional ◽  
Wide Range ◽  
Smoking Duration

Introduction. In Russian Federation, there are no comprehensive studies assessing the quality of life and risk factors for vitamin D deficiency and insufficiency, taking into account its status in different geographic latitudes.Aim. To assess the quality of life and risk factors for vitamin D deficiency and insufficiency among the population living in the regions of the Russian Federation located at latitudes from 45 ° to 70 °.Materials and methods. The first stage of the Russian multicenter non-interventional registry study using the “cross-sectional” method was carried out from March 2020 to May 2020.Results and discussion. According to the results of the correlation analysis, qualitative and quantitative factors were identified, presumably being risk factors for vitamin D deficiency and deficiency. Qualitative risk factors include: education; alcohol consumption; being in direct sunlight for more than 30 minutes a day; visit to the solarium; using sunscreen; drinking coffee; taking medications (not vitamin-mineral complexes). Quantitative factors include: visits to specialists (total per year); smoking (duration, years); exercise for more than 30 minutes a day, once a week; being in direct sunlight for more than 30 minutes a day.Conclusion. A wide range of risk factors for vitamin D deficiency dictates the need for their further study to clarify the category of persons who are shown targeted biochemical screening with subsequent drug correction.

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