scholarly journals Assessment of reproductive potential in patients after myomectomy

2021 ◽  
Vol 8 (1) ◽  
pp. 35-39
Author(s):  
Yan Van ◽  
Yuliya A. Romadanova ◽  
Alla A. Bakhvalova ◽  
Ekaterina V. Fedina ◽  
Aleksandr A. Zinov’yev ◽  
...  
Keyword(s):  
Surgical Approach ◽  
Ovarian Function ◽  
Reproductive Potential ◽  
Morphological Structure ◽  
Clinical Situation ◽  
Functional Restoration ◽  
Hormonal Profile ◽  
Abdominal Myomectomy ◽  
Time Required ◽  
Selection Of

The aim of the study is to assess the restoration of anatomical and functional integrity of the uterus and identify changes in hormonal profile in women after laparoscopic and abdominal myomectomy. Material and methods. 58 patients aged 36,2 5,9 years old with uterine myoma underwent myomectomy: 31 patients underwent laparoscopic myomectomy and 27 patients underwent abdominal myomectomy. The selection of surgical approach didnt depend on the size, the number and localization of uterine myomas and the patients concomitant pathology. The hormonal profile of the patients including AMH level was assessed befor myomectomy and in the 6 months after the operation. Postoperative assessment was performed on day 5th8th after surgery and in 1 and 6 months after myomectomy. Results. No significant differences were found in the processes of reparation of the uterus and in hormonal profile of the patients after laparoscopic or abdominal myomectomy. The time required for the patients reabilitation and for the restoration of the ovarian function and uterine morphological structure was similar in both groups. Conclusion. The hormonal profile of the patients and the anatomical and functional restoration of myometrium after myomectomy doesnt depend on the surgical approach if myomectomy is performed by an experienced surgeon after the correct assessment of the clinical situation.

Revising the Indications of Transtemporal Surgical Approaches in the Modern Endoscopic Era of Skull Base Surgery: A Dying Art

2020 ◽  
Author(s):  
Ravi Sankar Manogaran ◽  
Raj Kumar ◽  
Arulalan Mathialagan ◽  
Anant Mehrotra ◽  
Amit Keshri ◽  
...  
Keyword(s):  
Skull Base ◽  
Surgical Approach ◽  
Nerve Palsy ◽  
Tertiary Care ◽  
Surgical Approaches ◽  
Microsurgical Anatomy ◽  
Complete Excision ◽  
Lateral Skull Base ◽  
The Individual ◽  
Selection Of

Abstract Objectives The aim of the study is to emphasize and explore the possible transtemporal approaches for spectrum of complicated lateral skull base pathologies. Design Retrospective analysis of complicated lateral skull base pathologies was managed in our institute between January 2017 and December 2019. Setting The study was conducted in a tertiary care referral center. Main Outcome Measures The study focused on the selection of approach based on site and extent of the pathology, the surgical nuances for each approach, and the associated complications. Results A total of 10 different pathologies of the lateral skull base were managed by different transtemporal approaches. The most common complication encountered was facial nerve palsy (43%, n = 6). Other complications included cerebrospinal fluid (CSF) collection (15%, n = 2), cosmetic deformity (24%, n = 4), petrous internal carotid artery injury (7%, n = 1), and hypoglossal nerve palsy (7%, n = 1). The cosmetic deformity included flap necrosis (n = 2) and postoperative bony defects leading to contour defects of the scalp (n = 2). Conclusion Surgical approach should be tailored based on the individual basis, to obtain adequate exposure and complete excision. Selection of appropriate surgical approach should also be based on the training and preference of the operating surgeon. Whenever necessary, combined surgical approaches facilitating full tumor exposure are recommended so that complete tumor excision is feasible. This requires a multidisciplinary team comprising neurosurgeons, neuro-otologist, neuroanesthetist, and plastic surgeons. The surgeon must know precise microsurgical anatomy to preserve the adjacent nerves and vessels, which is necessary for better surgical outcomes.

scholarly journals SARS-CoV-2 and the reproductive system: known and the unknown..!!

2021 ◽  
Vol 26 (1) ◽  
Author(s):  
Indu Sharma ◽  
Priti Kumari ◽  
Anuradha Sharma ◽  
Subhas Chandra Saha
Keyword(s):  
Reproductive Health ◽  
Vertical Transmission ◽  
Reproductive System ◽  
Ovarian Function ◽  
Sperm Count ◽  
Sperm Concentration ◽  
Reproductive Potential ◽  
Oocyte Quality ◽  
Main Body ◽  
Close Monitoring

Abstract Background COVID-19 is the most recent zoonotic outbreak of coronaviruses. Mostly, it invades the cells of the respiratory system by binding to the receptor angiotensin-converting enzyme 2 (ACE2) which is also present in other organs like the kidney, testis, ovaries, breast, heart, and intestine, rendering them prone to be infected. The reproductive potential is a must for the sustenance of any species and it is our prime duty to safeguard the reproductive system of the present generation from such a deadly virus. The previously reported coronaviruses like severe acute respiratory syndrome coronavirus (SARS-CoV) had a detrimental impact on reproductive organs. There is a dearth of sufficient research to provide substantial evidence for the harmful effects of this novel virus on the reproductive system. Hence, our review compiles the knowledge available until now to boost research in this regard and to take the necessary steps in time. Main body of abstract Here we tried to compile all the data available on the effect of SARS-CoV-2 on the reproductive system as well as vertical transmission of the virus. All related articles published from February to August 2020 were reviewed and thoroughly analyzed. SARS-CoV-2 has been found to affect the sperm concentration and motility, thus degrading the fertility of males. In females, it is suspected that this virus affects the oocyte quality and ovarian function, resulting in infertility or miscarriage. Traces of SARS-CoV-2 virus have also been found in the breast milk of the infected mothers and the semen of infected males. Vertical transmission of SARS-CoV-2 has also been reported in some cases. Conclusion Based on the literature review, SARS-CoV-2 seems to have the potential of affecting both male and female reproductive tracts. This review brings together the findings and observations made in the area of reproductive health during the current pandemic. The reproductive system of the young population is preordained for subsequent disorders, infertility, reduced sperm count, and motility. Therefore, the research and medical practices should focus on possible vulnerability being posed by SARS-CoV-2 to the gametes and future generations. We, hereby, recommend close monitoring of young and pregnant COVID-19 patients concerning reproductive health with utmost priority.

Inflection and the Paradigm in German Nouns

1996 ◽  
Vol 8 (2) ◽  
pp. 219-263 ◽  
Author(s):  
Amanda Pounder
Keyword(s):  
Morphological Structure ◽  
Inflectional Morphology ◽  
Structure Dynamic ◽  
Morphological Component ◽  
Process Framework ◽  
Theoretical Issues ◽  
Selection Of ◽  
Modern Standard

The paper presents an analysis of noun inflection in Modern Standard German within a process framework. Familiar issues in the description of German inflectional morphology are discussed, such as analysis of weak nouns and of plural formation, and the establishment of inflectional classes, as well as broader theoretical issues such as postulation of identity relations (“zeros”). The elements of a process morphology are elaborated, including some that deviate from well-known models, such as recognition of a dynamic morphological component distinct from the static lexicon, expression of morphological semantics in the morphological component, and formalization of the notion of a paradigm. The paradigm is claimed to be an essential morphological structure, dynamic in nature, responsible for organization of the inflectional system and ensuring, in cooperation with operations applied to stems, correct sequencing and selection of these inflectional operations. It is also concluded that the inflectional class, derivative of the paradigm, may be a useful construct in some languages (including German), but is not a necessary one for all inflecting languages.

scholarly journals Critical appraisal of speech in noise tests: a systematic review and survey

2016 ◽  
Vol 5 (1) ◽  
pp. 13 ◽  
Author(s):  
Suhani Sharma ◽  
Rajesh Tripathy ◽  
Udit Saxena
Keyword(s):  
Critical Appraisal ◽  
Measurement Model ◽  
Test Time ◽  
Hearing Research ◽  
Speech In Noise ◽  
Hearing In Noise ◽  
Instrument Bias ◽  
Noise Test ◽  
Time Required ◽  
Selection Of

Speech in noise tests that measure the perception of speech in presence of noise are now an important part of audiologic tests battery and hearing research as well. There are various tests available to estimate the perception of speech in presence of noise, for example, connected sentence test, hearing in noise test, words in noise, quick speech-in-noise test, bamford-kowal-bench speech-in-noise test, and listening in spatialized noise-sentences. All these tests are different in terms of target age, measure, procedure, speech material, noise, normative, etc. Because of the variety of tests available to estimate speech-in-noise abilities, audiologists often select tests based on their availability, ease to administer the test, time required in running the test, age of the patient, hearing status, type of hearing disorder and type of amplification device if using. A critical appraisal of these speech-in-noise tests is required for the evidence based selection and to be used in audiology clinics. In this article speech-in-noise tests were critically appraised for their conceptual model, measurement model, normatives, reliability, validity, responsiveness, item/instrument bias, respondent burden and administrative burden. Selection of a standard speech-in-noise test based on this critical appraisal will also allow an easy comparison of speech-in-noise ability of any hearing impaired individual or group across audiology clinics and research centers. This article also describes the survey which was done to grade the speech in noise tests on the various appraisal characteristics.

scholarly journals Nutrição enteral em sistema fechado para pediatria: escolha com base na disponibilidade no comércio brasileiro e na rotulagem

2020 ◽  
Vol 35 (1) ◽  
pp. 70-76
Author(s):  
Anelise Pigatto Bissacotti ◽  
Franceliane Jobim Benedetti
Keyword(s):  
Enteral Nutrition ◽  
Closed System ◽  
Clinical Situation ◽  
Nutritional Composition ◽  
Enteral Diet ◽  
Pediatric Nutrition ◽  
Age Range ◽  
Selection Of ◽  
Better Than

Introduction: The enteral diet (ED) for pediatric nutrition should ensure the appropriate nutritional intake for the child and/or adolescent. Therefore, during the selection of ED, in addition to the patient’s needs, the characteristics and nutritional composition of the patients should be taken into account. Thus, the objective was to identify and characterize the diets for pediatric enteral nutrition, in a closed system, currently available in the Brazilian market, in order to assist nutritionists and doctors in prescription. Methods: The descriptive and documental research consisted in the identification of the diets for pediatric enteral nutrition, in a closed system, currently available in the Brazilian market and characterization of the diets, based on labeling data. The data of interest for the development of this study were collected in catalogs and official websites of the manufacturers and suppliers and books of enteral nutrition and nutrition in pediatrics. Results: In Brazil, nine pediatric enteral nutrition diets are available in a closed system, marketed by three manufacturers. It was found that the diets for pediatric enteral nutrition can be indicated for a wide age range, from one to 10 years and patients in different pathophysiological states. There is little variation in the levels and sources of macronutrients. Four enteral diets present fibers in their composition and 5 are hypotonic. Conclusions: The Brazilian market has a limited number of diets for pediatric enteral nutrition in a closed system, which makes prescribing a challenge for nutritionists and doctors. It can not be said that a particular pediatric enteral diet in closed system is better than another, each one has specific characteristics. This makes it necessary for to carefully evaluate the professionals adequacy of the diet to the patient’s clinical situation and individuality.

Can intubation be improved with endotracheal tubes marked with a color scale? Randomized controlled study.

2021 ◽  
Author(s):  
Juan Pablo Berazategui ◽  
Ramon Pio Larcade ◽  
Nestor Vain ◽  
Adriana Andrea Castro ◽  
Rose Mari Soria ◽  
...  
Keyword(s):  
Controlled Study ◽  
Endotracheal Tubes ◽  
Correct Placement ◽  
Randomized Controlled ◽  
Color Scale ◽  
Clinical Scenarios ◽  
Significant Difference ◽  
Different Color ◽  
Time Required ◽  
Selection Of

Objective: To assess if a color scale in the endotracheal tube (ETT) helps operators to correctly select the size and depth of placement of the ETT and decrease the time required, compared with the usual numeric ETT scale, in a mannequin model. Design/Methods: The study was conducted in 8 centers. Each size of the ETT was identified with different color by size. All experimental ETT had two painted zones: the mouthpiece and an area of 1 cm marked with the same color (to identify where the ETT should be taped above the lip). The operators were trained as part of the protocol using a video. Four clinical scenarios requiring endotracheal intubation were designed and randomly assigned. Each operator had to select the size and depth of ETT based on the BW, and then had to perform 4 intubation procedures. Results: 108 operators performed 432 intubations. No difference were found in the correct placement and selection of the ETT. Median time (in seconds) required for intubation using numeric vs. experimental tube was: for ETT Ø 2.5, 11.5 vs. 8 (p<0.001), ETTØ3,12 vs. 10 (p<0.001), ETT Ø 3.5, 15.5 vs.12 (p 0.003), ETT Ø4 12 vs.11 (p 0.019). Conclusions: No significant difference was observed in the selection and correct placement of the ETT. However, the intubation time was significantly shorter using the experimental ETT. This device could improve the effectiveness of intubation by reducing the time needed to properly place the ETT at mid trachea.

Bacteriophages: from isolation to application

2021 ◽  
Vol 22 ◽  
Author(s):  
Abdallah S. Abdelsattar ◽  
Alyaa Dawoud ◽  
Salsabil Makky ◽  
Rana Nofal ◽  
Ramy K. Aziz ◽  
...  
Keyword(s):  
Food Industry ◽  
Pathogenic Bacteria ◽  
Phage Genome ◽  
Morphological Structure ◽  
High Specificity ◽  
Potential Alternative ◽  
And Behavior ◽  
Phage Isolation ◽  
Different Levels ◽  
Selection Of

: Bacteriophages are considered as a potential alternative to fight pathogenic bacteria during the antibiotic resistance era. With their high specificity, they are being widely used in various applications: medicine, food industry, agriculture, animal farms, biotechnology, diagnosis, etc. Many techniques have been designed by different researchers for phage isolation, purification, and amplification, each of which has strengths and weaknesses. However, all aim at having a reasonably pure phage sample that can be further characterized. Phages can be characterized based on their physiological, morphological or inactivation tests. Microscopy, in particular, has opened a wide gate not only for visualizing phage morphological structure, but also for monitoring biochemistry and behavior. Meanwhile, computational analysis of phage genomes provides more details about phage history, lifestyle, and potential for toxigenic or lysogenic conversion, which translate to safety in biocontrol and phage therapy applications. This review summarizes phage application pipelines at different levels and addresses specific restrictions and knowledge gaps in the field. Recently developed computational approaches, which are used in phage genome analysis, are critically assessed. We hope that this assessment provides researchers with useful insights for selection of suitable approaches for Phage-related research aims and applications.

Proficient Normalised Fuzzy K-Means With Initial Centroids Methodology

2018 ◽  
Vol 8 (1) ◽  
pp. 42-59
Author(s):  
Deepali Virmani ◽  
Nikita Jain ◽  
Ketan Parikh ◽  
Shefali Upadhyaya ◽  
Abhishek Srivastav
Keyword(s):  
Unsupervised Learning ◽  
Real World ◽  
Learning Algorithms ◽  
Clustering Algorithms ◽  
Real World Data ◽  
World Data ◽  
Clustering Problem ◽  
Time Required ◽  
Selection Of

This article describes how data is relevant and if it can be organized, linked with other data and grouped into a cluster. Clustering is the process of organizing a given set of objects into a set of disjoint groups called clusters. There are a number of clustering algorithms like k-means, k-medoids, normalized k-means, etc. So, the focus remains on efficiency and accuracy of algorithms. The focus is also on the time it takes for clustering and reducing overlapping between clusters. K-means is one of the simplest unsupervised learning algorithms that solves the well-known clustering problem. The k-means algorithm partitions data into K clusters and the centroids are randomly chosen resulting numeric values prohibits it from being used to cluster real world data containing categorical values. Poor selection of initial centroids can result in poor clustering. This article deals with a proposed algorithm which is a variant of k-means with some modifications resulting in better clustering, reduced overlapping and lesser time required for clustering by selecting initial centres in k-means and normalizing the data.

Automation Tool Preparation in the Conditions of Production

2015 ◽  
Vol 770 ◽  
pp. 739-743 ◽  
Author(s):  
A.S. Yuanyushkin ◽  
D.V. Lobanov ◽  
D.A. Rychkov
Keyword(s):  
Comparative Analysis ◽  
Rational Design ◽  
Economic Effect ◽  
Optimal Choice ◽  
Processing Efficiency ◽  
Time Required ◽  
The Given ◽  
High Processing ◽  
Selection Of

The key task of the tool manufacturing is to create or to choose such a type of tool, which would permit to provide high processing efficiency, the best tool`s workability and the quality of the machined surfaces with minimum expenses and resources. The optimal choice of the constructive tool modifications from a variety of options takes much time required for the preparation of the tool to work. To solve this problem, we have developed software that allows you to create, organize and carry out a comparative analysis of structural instruments in order to identify rational option for the given conditions of production. Ordering and selection of a rational design of the instrument is carried out in accordance with established procedures of modeling and comparative analysis of design solutions. Application software can reduce design time technological process by 80...90%, and get a substantial annual economic effect.

The sex ratio of a gilt’s birth litter can affect her fitness as a breeding female

2018 ◽  
Vol 58 (9) ◽  
pp. 1567 ◽  
Author(s):  
J. Seyfang ◽  
R. N. Kirkwood ◽  
A. J. Tilbrook ◽  
C. R. Ralph
Keyword(s):  
Sex Ratio ◽  
Reproductive Performance ◽  
Reproductive Potential ◽  
Group Housing ◽  
Pork Industry ◽  
Welfare Issue ◽  
Breeding Herd ◽  
Uterine Environment ◽  
Animal Welfare Issue ◽  
Selection Of

Lifetime reproductive performance and behaviour are established in utero driven by genetics and the steroidal milieu of the uterine environment. Developing males synthesise androgens that can be absorbed by females in the litter. Consequently, the proportion of males in a litter has the potential to affect both lifetime reproductive performance and behaviour of female littermates. Although reproductive potential is understandably important for gilt selection, behaviour is becoming progressively more important as group housing of sows increases. Aggression can be a cause for removal from the breeding herd, and can also negatively affect reproductive performance and herd longevity. This review covers existing evidence of masculinisation in rodents and sheep, the mechanism causing masculinisation, and the knowledge gaps surrounding masculinisation in pigs. Premature culling of gilts is an economic and animal welfare issue in the pork industry resulting in low retention of gilts and reduced productivity. The selection of gilts needs to be improved to incorporate both lifetime reproductive potential and behaviour. We determined that there is cause to investigate the effect of the birth litter sex ratio of a gilt on her suitability for selection into the breeding herd.

Sign in / Sign up

Export Citation Format

Share Document