PECULIARITIES OF STRUCTURAL-FUNCTIONAL STATE OF THE KIDNEYS ACCORDING ELASTOGRAPHY SHEARWAVE IN CHILDREN WITH ARTERIAL HYPERTENSION ON THE BACKGROUND OF OBESITY

Introduction. Metabolic and hemodynamic consequences of obesity (insulin resistance and hyperglycemia, hypertension, dyslipidemia) rofm metabolic syndrome in adolescence and an accordingly high risk of cardiovascular morbidity and mortality in adulthood. In recent years, studies have shown that obesity and metabolic syndrome are independent risk factors for chronic kidney disease (CKD). Ultrasonography is the most commonly used noninvasive method for research of the kidneys in pediatric patients.Aim of the study: to assess new features of shear wave elastography for the diagnosis of structural-functional state of the kidneys in children with arterial hypertension and obesity. Materials and methods. Ultrasound examination of kidneys was performed using a digital portable ultrasound system ANGIODIN - sono / P - Ultra (NPF “BIOS” Russia). Was examined 83 children who underwent elastography shear wave parenchymal layer of the kidney definition of renal parenchymal stiffness in kPa.Results. In patients with arterial hypertension and obesity the results of elastography, shear waves we found significant differences in the elasticity of the renal parenchyma between those with arterial hypertension (group 1, n=37) and children with uncomplicated obesity (group 2, n=26). The elasticity of the renal parenchyma in patients of the control group (n=20) was significantly lower than in patients of the 1st and 2nd groups. The results show that in children of the 1st group with stable hypertension high values of the elasticity of the renal parenchyma were detected in 3,2 times more often in comparison with children of the 1st group were diagnosed with labile hypertension. Conclusion. The shear wave elastography is an informative noninvasive method of evaluation of the kidneys in children with arterial hypertension with obesity. This diagnostic approach can be used in pediatric patients as a screening method (before ABPM) to assess the risk of developing hypertension, degree of hypertension and the adequacy of current anti-hypertensive therapy.

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Evaluation of Ovaries in Patients with Polycystic Ovary Syndrome using Shear Wave Elastography

Current Medical Imaging Formerly Current Medical Imaging Reviews ◽

10.2174/1573405615666190114150538 ◽

2020 ◽

Vol 16 (5) ◽

pp. 578-583

Author(s):

Aysegul Altunkeser ◽

Zeynep Ozturk Inal ◽

Nahide Baran

Keyword(s):

Shear Wave ◽

Large Scale ◽

Polycystic Ovary ◽

Shear Wave Elastography ◽

Left Ovary ◽

Control Group ◽

Tissue Elasticity ◽

Group I ◽

Pcos Group ◽

The Right

Background: Shear wave electrography (SWE) is a novel non-invasive imaging technique which demonstrate tissue elasticity. Recent research evaluating the elasticity properties of normal and pathological tissues emphasize the diagnostic importance of this technique. Aims: Polycystic ovarian syndrome (PCOS), which is characterized by menstrual irregularity, hyperandrogenism, and polycystic overgrowth, may cause infertility. The aim of this study was to evaluate the elasticity of ovaries in patients with PCOS using SWE. Methods: 66 patients diagnosed with PCOS according to the Rotterdam criteria (PCOS = group I) and 72 patients with non-PCOS (Control = group II), were included in the study. Demographic and clinical characteristics of the participants were recorded. Ovarian elasticity was assessed in all patients with SWE, and speed values were obtained from the ovaries. The elasticity of the ovaries was compared between the two groups. Results: While there were statistically significant differences between the groups in body mass index (BMI), right and left ovarian volumes, luteinizing hormone and testosterone levels (p<0.05), no significant differences were found between groups I and II in the velocity (for the right ovary 3.89±1.81 vs. 2.93±0.72, p=0.301; for the left ovary 2.88±0.65 vs. 2.95±0.80, p=0.577) and elastography (for the right ovary 36.62±17.78 vs. 36.79±14.32, p=0.3952; for the left ovary 36.56±14.15 vs. 36.26±15.10, p=0.903) values, respectively. Conclusion: We could not obtain different velocity and elastography values from the ovaries of the patients with PCOS using SWE. Therefore, further large-scale studies are needed to elucidate this issue.

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The relationship of the shear wave elastography findings of patients with unilateral lumbar disc herniation and clinical characteristics

BMC Musculoskeletal Disorders ◽

10.1186/s12891-019-2814-7 ◽

2019 ◽

Vol 20 (1) ◽

Author(s):

Qingyuan Wang ◽

Hao Zhang ◽

Jinxin Zhang ◽

Hanqi Zhang ◽

Hui Zheng

Keyword(s):

Sciatic Nerve ◽

Shear Wave ◽

Lumbar Disc Herniation ◽

Disc Herniation ◽

Clinical Characteristics ◽

Lumbar Disc ◽

Shear Wave Elastography ◽

Control Group ◽

Symptom Duration ◽

Foraminal Stenosis

Abstract Background The aim of this study was to find out whether the shear wave elastography (SWE) findings of patients with unilateral lumbar disc herniation (LDH) were related to clinical characteristics. Methods For this purpose, the study group included patients (N = 20; 13 male, 7 female) with complaints of unilateral sciatica, with foraminal stenosis caused by one level of LDH (L4-L5 or L5-S1). An gender-and age-matched control group (N = 27; 16 male, 11 female) was included. All the patients were examined on both the axial and longitudinal planes bilaterally at the same level using a convex array probe (1- 6 MHz, Supersonic Imagine, Aix en Provence, France). Results The sciatic nerve stiffness measured on longitudinal planes of the affected side was significantly higher than unaffected side (p < 0.001) and the control group (P < 0.05). Furthermore, the symptom duration of unilateral LDH is positively correlated with the stiffness the sciatic nerve (r = 0.52, p = 0.019). Conclusion According to these findings, ultrasound imaging can be considered as a useful tool to detect changes in the sciatic nerve due to disc herniation. This technique will have a promising prospect for many patients with unilateral LDH in monitoring stiffness during rehabilitation and before or after surgery.

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Assessment of microcirculation and stiffness of renal parenchyma in patients with hemorrhagic fever with renal syndrome using shear wave elastography

Infekcionnye bolezni ◽

10.20953/1729-9225-2019-1-52-57 ◽

2019 ◽

Vol 17 (1) ◽

pp. 52-57

Author(s):

T.M. Kamenshchikova ◽

◽

K.M. Manakhov ◽

A.B. Babochkin ◽

O.V. Malinin ◽

...

Keyword(s):

Shear Wave ◽

Shear Wave Elastography ◽

Hemorrhagic Fever ◽

Renal Parenchyma

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Evaluation of tendinosis of the long head of the biceps tendon by strain and shear wave elastography

Medical Ultrasonography ◽

10.11152/mu-1323 ◽

2018 ◽

Vol 20 (2) ◽

pp. 192 ◽

Cited By ~ 5

Author(s):

Mehmet Hamdi Sahan ◽

Mikail Inal ◽

Veysel Burulday ◽

Turgut Kultur

Keyword(s):

Shear Wave ◽

Biceps Tendon ◽

Shear Wave Elastography ◽

Tissue Type ◽

Diagnostic Tools ◽

Control Group ◽

Type I ◽

Color Mapping ◽

Significant Difference ◽

Long Head

Aim: To investigate strain (SE) and shear wave elastography (SWE) characteristics of the long head of the biceps tendon (LHBT) tendinosis in comparison with magnetic resonance imaging (MRI) findings.Material and methods: Twenty patients with a MRI diagnosis of tendinosis and twenty healthy subjects with normal LHBT in MRI were prospectively examined by SE and SWE. SE color mapping was divided into four types in accordance with elasticity designs: type I predominantly blue (hardest tissue), type II predominantly blue-green (hard tissue), type III predominantly green (intermediate tissue), type IV predominantly green-yellow-red (soft tissue). Quantitative measurements of LHBT hardness with SWE were analyzed in kilopascals (kPa).Results: In the tendinosis group SE types in transverse scan were I in 24% of tendons, II in 50%, III in 25%, and in longitudinal scan I in 15%, II in 75%, and III in 10%. In the control group SE types in transversescan were II in 10% of tendons, III in 55%, IV in 35%, and in longitudinal scan II in 10%, III in 55%, and IV in 35%. SWE values in transverse scan were 38.32±7.2 kPa in the tendinosis group and 18.6±3.1 kPa in the control groupand in longitudinal scan 39.42±7.4 kPa in the tendinosis group, and 20.62±4.6 in the control group. There was a statistically significant difference in terms of elasticity patterns between the tendinosis and control groups (p<0.001). The receiver operating characteristic curve analysis was perfect and a cut-off value of tranverse 25.8 kPa and longitudinal, 24.6 kPa shear values had very high sensitivity and specificity for tendinosis.Conclusion: SE and SWE may be useful diagnostic tools for LHBT tendinosis when considering usability, cost effectiveness, and patient preference compared to MRI.

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The Role of Shear Wave Ultrasound Elastography in the Diagnosis of Adenomyosis and / or Hyperplastic Processes of the Endometrium

Ukraïnsʹkij žurnal medicini bìologìï ta sportu ◽

10.26693/jmbs05.06.129 ◽

2020 ◽

Vol 5 (6) ◽

pp. 129-135

Author(s):

V. V. Lazurenko ◽

◽

T. V. Melikhova

Keyword(s):

Shear Wave ◽

Uterine Leiomyoma ◽

Diagnostic Errors ◽

Shear Wave Elastography ◽

Diagnostic Methods ◽

Ultrasound Elastography ◽

Control Group ◽

Yellow Light ◽

Light Blue ◽

The Third

Today, hysteroscopy, ultrasound and magnetic resonance imaging are most often used in clinical practice for the diagnosis of adenomyosis. However, the high frequency of diagnostic errors (from 20 to 40%), depending on the experience of the operator and equipment, detailing the structure of the myometrium and the parameters of ultrasound differentiation of adenomyosis, requires the search for new optimal diagnostic methods. The purpose of our study was to determine the parameters of ultrasound elastography of the shear wave in patients with adenomyosis and / or hyperplastic processes of the endometrium. Material and methods. The study included 128 patients aged from 27 to 53 years (mean 39.4 ± 8.6). The first group included 38 (29.6%) patients diagnosed with grade I-II adenomyosis, the second group had 41 (32.1%) patients with a combination of grade I-II adenomyosis with endometrial hyperplastic processes and / or uterine leiomyoma, the third group consisted of 39 (30.5%) women only with hyperplastic processes of the endometrium. The control fourth group included 10 (7.8%) women without endometrial pathology, who sought women's advice on primary infertility. Results and discussion. When performing shear wave elastography, significant differences in the color of myometrial mapping were found between patients of the first, third and control groups (p <0.001). Unchanged myometrium in all patients of the control group was represented by shades of blue, and the staining was uniform in 9 (90%) subjects. In patients of the first group, the myometrium was stained with shades of red in 31 (81.63%) cases and shades of yellow in 3 (7.8%) cases; in 23 (60.5%) cases there was inhomogeneous red staining and in 14 (36.8%) cases staining was inhomogeneous in shades of red-yellow-light blue. When performing elastography in patients of the second group in the projection of the myoma was more often detected staining in shades of red in 20 (48.8%) cases, yellow in 6 (14.6%) and light blue in 3 (7.3%) cases; in 28 (68.3%) cases there was inhomogeneous red staining and in 19 (46.3%) cases staining was inhomogeneous in shades of red-yellow-light blue. In the third group in the projection of the leiomatous node was more often determined by staining in shades of red in 22 (56.4%) cases, yellow in 8 (20.5%) and light blue in 6 (15.4%) cases, colors on the background of the blue myometrium; inhomogeneous staining of myomatous nodes was detected in 31 (79.5%), and homogeneous staining was in 7 (17.9%) cases. Unchanged myometrium in the control group was characterized by significantly lower values of the Young's modulus 25.2 (17.9-34.1 kPa), while in the group of adenomyosis the average value of Emean reached 71.8 (17.9-281.3 kPa), was maximally high and significantly different from the indicators of the control group and from the indicators of group 3 patients 29.6 (13.5-58.9 kPa). The rates of patients of the second group, in whom grade I-II adenomyosis was combined with endometrial hyperplastic processes and / or uterine leiomyoma 54.7 (15.6-133.9 kPa) were also significantly higher than the values of the control group and the third group. Conclusion. Shear wave ultrasound is a minimally invasive and accessible method of high-quality preoperative diagnosis, necessary to avoid hysterectomy and clarify the diagnosis without surgery, which is recommended for use in practice to improve the accuracy of diagnosis of adenomyosis

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Is shear wave elastography relevant in the diagnosis of polycystic ovarian syndrome?

Medical Ultrasonography ◽

10.11152/mu-1849 ◽

2019 ◽

Vol 21 (2) ◽

pp. 158 ◽

Cited By ~ 1

Author(s):

Ersen Ertekin ◽

Ozgür Deniz Turan ◽

Ozum Tuncyurek

Keyword(s):

Shear Wave ◽

Polycystic Ovarian Syndrome ◽

Imaging Finding ◽

Shear Wave Elastography ◽

Left Ovary ◽

Control Group ◽

Diagnostic Efficacy ◽

Significant Difference ◽

The Right ◽

Ovarian Syndrome

Aim: The aim of this study was to determine the contribution of Shear Wave Elastography (SWE) to the diagnosis of polycystic ovarian syndrome (PCOS).Material and methods: Thirty-seven patients with PCOS diagnosis criteria were included in the study. Sixteen volunteer patients without hormonal disturbances and with normal menstrual cycles were evaluated as the control group. Gray scale ultrasonography (US) and SWE measurements in both ovaries were performed by a single radiologist who was blinded to the clinical and laboratory results.Results: The SWE measurements in PCOS group were 8.4±2.0 kPafor the right ovary and 9.4±3.9 kPa for the left ovary and in the control group 7.8±4.1 for the right ovary and 8.6±2.5 kPa for the left ovary. There was no statistically significant difference between the PCOS and the control group according to the SWE results (for right ovary p=0.356, for left ovary p=0.258, and total ovary p=0.293).Conclusions: The ovarian morphology isstill the most reliable imaging finding in the diagnosis of PCOS, although it is controversial especially among adolescents. Although the diagnostic efficacy of SWE is demonstrated in a variety of soft tissue lesions, we did not find any significant contribution of SWE to the diagnosis PCOS. Therefore, the promising value of elastography is yet to be defined for the diagnosis of PCOS.

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The relationship of the shear wave elastography findings of patients with unilateral lumbar disc herniation and clinical characteristics

10.21203/rs.2.11168/v3 ◽

2019 ◽

Author(s):

qingyuan wang ◽

jinxin zhang ◽

hanqi zhang ◽

hui zheng ◽

Hao Zhang

Keyword(s):

Sciatic Nerve ◽

Shear Wave ◽

Lumbar Disc Herniation ◽

Disc Herniation ◽

Clinical Characteristics ◽

Lumbar Disc ◽

Shear Wave Elastography ◽

Control Group ◽

Symptom Duration ◽

Foraminal Stenosis

Abstract Abstract Background The aim of this study was to find out whether the shear wave elastography (SWE) findings of patients with unilateral lumbar disc herniation (LDH)were related to clinical characteristics . Methods For this purpose,the study group included patients(N=20; 13 male, 7 female) with complaints of unilateral sciatica , with foraminal stenosis caused by one level of LDH (L4-L5 or L5-S1).An gender-and age-matched control group(N=27; 16 male, 11 female) was included.All the patients were examined on both the axial and longitudinal planes bilaterally at the same level using a convex array probe(1- 6MHz,Supersonic Imagine,Aix en Provence,France). Results The sciatic nerve stiffness measured on longitudinal planes of the affected side was significantly higher than unaffected side (p < 0.001)and the control group (P<0.05).Furthermore,the symptom duration of unilateral LDH is positively correlated with the stiffness the sciatic nerve(r=0.52,p=0.019). Conclusion According to these findings, ultrasound imaging can be considered as a useful tool to detect changes in the sciatic nerve due to disc herniation. This technique will have a promising prospect for many patients with unilateral LDH in monitoring stiffness during rehabilitation and before or after surgery. Keywords Ultrasound 、Sciatic nerve、Shear wave elastography、lumbar disc herniation

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The relationship of the shear wave elastography findings of patients with unilateral lumbar disc herniation and clinical characteristics

10.21203/rs.2.11168/v2 ◽

2019 ◽

Author(s):

qingyuan wang ◽

jinxin zhang ◽

hanqi zhang ◽

hui zheng ◽

Hao Zhang

Keyword(s):

Sciatic Nerve ◽

Shear Wave ◽

Lumbar Disc Herniation ◽

Disc Herniation ◽

Clinical Characteristics ◽

Lumbar Disc ◽

Shear Wave Elastography ◽

Control Group ◽

Symptom Duration ◽

Foraminal Stenosis

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Metabolic syndrome – a risky combination

ARS Medica Tomitana ◽

10.2478/v10307-012-0036-4 ◽

2012 ◽

Vol 18 (4) ◽

pp. 188-192

Author(s):

R. S. Şuţa ◽

Cristina Şuţa

Keyword(s):

Metabolic Syndrome ◽

Cardiovascular Risk ◽

Arterial Hypertension ◽

Central Obesity ◽

International Diabetes Federation ◽

Hard Core ◽

Common Finding ◽

The Metabolic Syndrome ◽

Cardiovascular Morbidity And Mortality ◽

Study Population

Abstract The metabolic syndrome is characterized by a cluster of related clinical, anthropometric and biochemical features such as central obesity, dysglycaemia, dyslipidaemia and hypertension. It is highly prevalent in the general population (approximately 22%), with differences in relation to race, gender, and age. It carries an increased cardiovascular morbidity and mortality, which makes an early and correct assessment mandatory. The prevalence of the metabolic syndrome is very high in type 2 diabetes patients, in whom it influences the risk of chronic complications. The aim of the present report is to explore the characteristics and the combination types of the metabolic syndrome and to assess the cardiovascular risk in patients presenting this clinical entity. 329 patients consecutively diagnosed with metabolic syndrome were included in the study, both men and women, no limit regarding age. Patient selection was made during the periodic medical visits in the outpatient clinics of Diabetes, Cardiology and Internal Medicine. Metabolic syndrome (MetS) was diagnosed according to 2005 International Diabetes Federation (IDF) Criteria. Women were more frequent than men, mean age was 59.08±888 and they all had central obesity (it is the major criteria of 2005 IDF definition for MetS) .The diagnosis of the metabolic syndrome was fulfilled with only 3 criteria, most of the times. The complete metabolic syndrome was the rarest, less than 25% of the patients presenting all 5 definition criteria and it was more frequent among men (men 39.2% vs women 15.9%: p < 0.0001). Apart from central obesity, which is mandatory for diagnosing MetS and thus present in all patients, arterial hypertension is the most common finding in our study population, with impaired glycaemia and increased triglycerides occupying the second and third place, respectively. Central obesity, arterial hypertension and impaired glycaemia represent the most frequent combination, a real „hard core” of MetS. As expected, the cardiovascular risk was high in the study population. The cardiovascular „score” of our patients increased significantly with the number of components used for the diagnosis of MetS (MetS with 3 elements vs MetS with 4 elements vs MetS with 5 elements: SCORE - 5.36 ± 7.07 vs 7.66 ± 8.63 vs 8.52 ± 8.34, p < 0.01).

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Feasibility of 2-D ultrasound shear wave elastography of fetal lungs in case of threatened preterm labour: a study protocol

BMJ Open ◽

10.1136/bmjopen-2017-018130 ◽

2017 ◽

Vol 7 (12) ◽

pp. e018130 ◽

Cited By ~ 5

Author(s):

Nicolas Mottet ◽

Sébastien Aubry ◽

Chrystelle Vidal ◽

Guillaume Boiteux ◽

Jean-Patrick Metz ◽

...

Keyword(s):

Shear Wave ◽

Study Protocol ◽

Preterm Labour ◽

Shear Wave Elastography ◽

Fetal Lung ◽

Normal Lung ◽

Control Group ◽

National Agency ◽

Research Committee ◽

Fetal Lungs

Introduction2-D ultrasound shear wave elastography (SWE) could be considered as a new noninvasive tool for monitoring fetal lung development based on evaluation of mechanical properties during pregnancy. Interesting results are available concerning the use of SWE on developing organs, especially on premature infants and animal models. The main objective in this study is to evaluate the feasibility of 2-D SWE in human fetal lungs between 24 and 34 weeks of gestation (WG). The secondary objective is to modellise fetal lung-to-liver elastography ratio (LLE ratio) and to assess variations between normal lung and lung surfactant-enriched after a corticosteroids course indicated for a threatened preterm labour (TPL).Methods/designA prospective case-control study will be performed between 24 and 34 WG. Fetal lungs and liver will be explored by SWE into two groups: fetuses of women with an uncomplicated pregnancy (control group) and fetuses of women with a TPL requiring administration of corticosteroids (cases group). LLE ratio will be defined as the value of the lung elasticity divided by the value of the liver elasticity.Primary judgement criterion is the value of elasticity modulus expressed in kilopascal. Lungs and liver will be explored through three measurements to define the most reproducible regions with the lowest intra- and inter-observer variability. Feasibility will be evaluated by assessing the number of examinations performed and the number of examinations with interpretable results. Intra- and inter-observer reproducibility will be evaluated by means of the intra-class correlation coefficient.Ethics and disseminationApproval of the study protocol was obtained from the human ethical research committee (Comité de Protection des Personnes EST II, process number 15/494) and the French National Agency for Medicines and Health Products Safety (process number 2015-A01575-44). All participants will sign a statement of informed consent.Trial registration numberNCT02870608; Recruiting.

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