Determination of total and residual nitrogen in normal and pathologically altered skin in various skin and venereal diseases

1936 ◽  
Vol 32 (12) ◽  
pp. 1500-1500
Keyword(s):  
Healthy People ◽  
Main Task ◽  
Venereal Diseases ◽  
Residual Nitrogen ◽  
Quantitative Content

Before embarking on the implementation of their main task, the authors preliminarily studied the quantitative content of nitrogen in the skin and blood in rabbits and healthy people

The New Swedish Cyprus Expedition 2010. Excavations at Dromolaxia Vizatzia/Hala Sultan Tekke. Preliminary results

2011 ◽  
Vol 4 ◽  
pp. 69-98 ◽  
Author(s):  
Peter M. Fischer ◽  
Patrik Klingborg ◽  
Fanny Kärfve ◽  
Fredrika Kärfve ◽  
C. Hagberg ◽  
...  
Keyword(s):  
Ground Penetrating Radar ◽  
Main Task ◽  
Phase 2 ◽  
The North ◽  
12Th Century ◽  
Area 6 ◽  
Recent Phase ◽  
The Rich ◽  
Ground Penetrating

Determination of the complete occupational sequence of the site, including investigation of pre-12th century levels which were thoroughly studied by P. Åström since the 1970s, is the main task of the planned project. During the course of the expedition (NSCE11) in spring 2010 a ground-penetrating radar survey (GPR) was carried out at Dromolaxia Vizatzia/Hala Sultan Tekke in Area 6, leading to the discovery of a large Late Cypriote complex. The compound is bordered to the north by a substantial wall, against which nine rooms (so far) could be exposed. Two occupational phases have been verified but there are indications of a third. The suggested functions of the various structures of the most recent phase are: living, working, storage and administration spaces. The rich find contexts point to the production of textiles and metal objects, and the locally produced pottery is generally of a high quality. There are also many imports, mainly from the Mycenaean sphere of culture. The locally produced vessels from Phase 2 include the “Creature krater” which is a masterpiece of a high artistic standard. Another piece of elevated artistry is the piece of a “Warrior vase”.

scholarly journals Determination of hydroxycinnamic acids in the herb of stachys sieboldii miq

2016 ◽  
Author(s):  
S. M. Marchyshyn ◽  
L. V. Husak ◽  
T. S. Berdey
Keyword(s):  
Hydroxycinnamic Acids ◽  
Qualitative Composition ◽  
Quantitative Content ◽  
Stachys Sieboldii

In the article the results of study of qualitative composition and quantitative content of hydroxycinnamic acids in the herb of Stachys sieboldii Miq. are presented. By the method  of HPLC it was established the presence of chlorogenic, rosemarinic, caffeic and p-coumaric acids. Quantitative content of hydroxycinnamic acids was determined by the method of spectrophotometry.

scholarly journals Diagnostic possibilities of accurate determination of the time since death on the concentration of electrolytes in the vitreous body of the human eye

2021 ◽  
pp. 79-85
Author(s):  
Yuliia Sarkisova
Keyword(s):  
Accurate Determination ◽  
Vitreous Body ◽  
Statistical Processing ◽  
Test Material ◽  
Main Task ◽  
Time Since Death ◽  
Exclusion Criteria ◽  
Cardiovascular Pathology ◽  
Human Eye

In this paper the results of modern scientific researches are analyzed and the possibilities of the method of establishing the amount of K+ and Na+ in the vitreous body (VB) of a person for solving problems of practical forensic medicine are studied. The aim of the work. To investigate the possibilities of accurately establishing the time since death (TSD) by determining the amount of electrolytes (K+ and Na+) of human VB. Materials and methods. VB samples from 120 deaths due to cardiovascular pathology (exclusion criteria: eyeball injuries, traumatic brain injury, exogenous intoxications) were studied. The study of the test material was performed on an analyzer of electrolytes and gases ROCHE COBAS B121. The main task was to analyze and establish the dependence of the change in the amount of K+ and Na+ of the VB on the TSD. Statistical processing of the obtained results was performed using Statistica software. Results. In all cases, on average in the first 6 hours, its amount was 7,4 mmol/l, after 6-12 hours – 9,8 mmol/l, after 12-18 hours – 12,1 mmol/l, after 18-24 hours – 16,5 mmol/l, after 24-36 hours – 20,2 mmol/l, after 36-48 hours – 25,3 mmol/l. The amount of Na+ ranged from 120 to 200 mmol/l. Conclusions. It is established that the number of electrolytes of the VB of the human eye naturally changes with increasing postmortem interval, which allows to use this technique to determine the TSD. In particular, the accuracy of setting the DNS by the number of K+ – 4-6 hours between 1 and 18 hours after death. There is an increase in the range of accuracy at a later date of the TSD.

scholarly journals Comparative pharmakognostical study of roots of Rosa Majalis Herrm. and Rosa Canina L.

2021 ◽  
pp. 71-78
Author(s):  
Tetiana Oproshanska ◽  
Olga Khvorost ◽  
Kateryna Skrebtsova ◽  
Konradas Vitkevicius
Keyword(s):  
Cell Walls ◽  
Raw Materials ◽  
Total Polyphenols ◽  
Diagnostic Features ◽  
Rosa Canina ◽  
Plant Raw Materials ◽  
Quantitative Content ◽  
Microscopic Features ◽  
Boundary Limits

The aim is to conduct a comparative pharmacognostical study of the series of roots of Rosa (R.) majalis Herrm. and Rosa (R.) canina L. with the establishment of diagnostic features of morphological and anatomical structure and boundary limits of numerical indicators of raw materials. Materials and methods. The fresh and dry raw materials were used to study the macroscopic microscopic features by microscope Delta optical BioLight 300 (Poland). Determination of total polyphenols was performed by spectrophotometry (on a spectrophotometer Optizen POP (Korea)) and HPLC (chromatograph an Agilent 1200 3 D LC System Technologies (USA)). Results. The morphological (nature of the surface (periderm) and fracture) and anatomical (color of cell walls and their cavities; location of the sclerenchyma; the presence of a crystalline coating of the sclerenchyma at the root of R. canina; of various elements of the remains of the tetraarchic conducting bundle in the center of the root) diagnostical features of roots of R. majalis and R. Canina were established. Comparing the numerical values of loss on drying (not more than 10 %), total ash (not more than 5 %), extractable matter (not less than 9 %) and the quantitative content of total polyphenols (not less than 4 %) it was determined that both types of raw materials according to these indicators are almost indistinguishable. Conclusions. Loss on drying, total ash, extractable matter and content of total polyphenols of the root of R. majalis and R. canina do not have significant differences, that is why the root of both plant species can be used as medicinal plant raw materials such as “Rose root”. The obtained data will be used in further research when creating methods of quality control of plant raw materials and phytomedicines

scholarly journals THE PROBLEM OF ANDROGYNOUS IDEAL OF A HUMAN BEING IN V.V. ROZANOV’S PHILOSOPHY OF SEX

2021 ◽  
pp. 55-62
Author(s):  
Tatyana A. Ivanova ◽  
Keyword(s):  
Old Testament ◽  
Married Couple ◽  
Russian Philosophy ◽  
Main Task ◽  
Unsuccessful Attempt ◽  
Concept Of God ◽  
Metaphysical Principle ◽  
The Ideal ◽  
Love Dynamics

The purpose of this article is a philosophical and anthropological analysis of the ideal of androgyne in V.V. Rozanov’s metaphysics of sex. The main focus is on the comparison of the destructive and constructive forms of the androgyne in his philosophy. According to the philosopher, destructive forms include people of «moonlight» or «third sex», who are considered the founders of New Testament Christianity, denying the life of the flesh. Constructive forms are the natural androgyny of a child and the androgyny of a married couple, which reveals itself in love, dynamics, mutual complementarity of a man and a woman. The paper draws parallels between N.A. Berdyaev’s and V.V. Rozanov’s concepts of androgyne, which are antipodal in terms of direction of thought but have common meanings. It is concluded that thesimilarity between the concepts lies in the understanding of gender as a dynamic and metaphysical principle that penetrates through not only the bodily but also the spiritual life of a person, and therefore cannot be rejected. The concepts are also similar in that they draw a boundary between the androgyne and the hermaphrodite, of which the former is the ideal of the human wholeness, while the latter is an unsuccessful attempt to achieve it. The differences between these philosophers consist in the priority of spiritual love in Berdyaev’s system and worldly, bodily love in Rozanov’s, as well as in a different understanding of the process of an androgyne being generated in a person, which, in Berdyaev’s conception, is individual and arises in each of the persons who are in love with each other, while, according to Rozanov, it is exclusively achievable in couples. The paper also pays attention to Rozanov’s own theology, which renews the Old Testament family ideals, offering the concept of God as a «sexual» being and proposing to consider the act of love within marriage as a sacred mystery that unites a person with God in co-creation. The study allows us to rethink the modern problems of gender self-determination of a person, returning to the metaphysical foundations of the Russian philosophy of gender, the main task of which was the synthesis of the spiritual and bodily principles in a person.

Induction Suspension of Conductive Microring and Its Gyroscopic Stabilization

2021 ◽  
Author(s):  
Dmitrii Skubov ◽  
Ivan Popov ◽  
Pavel Udalov
Keyword(s):  
Magnetic Field ◽  
Steady State ◽  
Eddy Current ◽  
Equilibrium Position ◽  
Critical Case ◽  
Conservative System ◽  
Critical Value ◽  
Main Task ◽  
Gyroscopic Stabilization

Abstract The main task of our work is determination of possible levitation of micro-ring with eddy current in magnetic field of down ring with set alternating current and determination of critical value of «ohmic» damping separated field of parameters, at which motions of suspension ring transit from divergent to meeting to steady-state equilibrium position. I. e. in this critical case the motion practically coincides with motions of conservative system. The possibility of gyroscopic stabilization of suspension ring taking into account initial set rotation is considered. Thereby it can serve as contactless micro-gyroscope.

COTTONWEED MARSH (MARSH). CHEMICAL COMPOSITION OF ETHANOL EXTRACT

2020 ◽  
Vol 5 (4) ◽  
pp. 29-32
Author(s):  
V. Platonov ◽  
V. Dunaev ◽  
G. Suhih ◽  
M. Shatskiy ◽  
M. Volochaeva
Keyword(s):  
Chemical Composition ◽  
Mass Spectra ◽  
Ethanol Extract ◽  
Structural Group ◽  
Quantitative Content ◽  
Wide Range ◽  
Structural Formulas ◽  
First Time ◽  
Sulfur Containing

For the first time, a detailed study of the chemical composition of ethanol extract of dried marsh (swamp), a product obtained after preliminary exhaustive last ex-traction with n-hexane, toluene, chloroform and acetone was performed. Chromatography-mass spectrometry made it possible to identify 119 individual compounds in this extract with the determination of their quantitative content, mass spectra and structural formulas, and the calculation of the structural-group composition was performed. A characteristic feature of the extract is the presence of significant amounts of nitrogen and sulfur-containing compounds (20.04), esters (21.47), sterols (18.54), carboxylic acids (8.15) and hydrocarbons (7.15) (wt. % of the extract). In addition, the extract contains phenols, ketones, aldehydes, alcohols and glycosides: 5.01; 4.34; 4.88; 3.16 and 3.12 (wt. % of the extract), respectively. Dominance in the extract of nitrogen-sulfur-containing and compounds; environment of sterols-betulin and its derivatives, esters, as well as the presence of different structure of phenols, glycosides, aldehydes and alcohols makes it possible to assume a wide range of pharmacological activity of drugs based on ethanol extract of dried marsh (marsh).

scholarly journals HPLC determination of phenolic compounds content in Parmelia sulcata and Parmelia vagans thalli

Pharmacia ◽  
2019 ◽  
Vol 66 (4) ◽  
pp. 161-164
Author(s):  
O. A. Kyslychenko ◽  
Viktoriia V. Protska ◽  
Iryna O. Zhuravel
Keyword(s):  
Phenolic Compounds ◽  
Inflammatory Diseases ◽  
Raw Materials ◽  
Folk Medicine ◽  
Usnic Acid ◽  
Total Content ◽  
Raw Material ◽  
Parmelia Sulcata ◽  
Quantitative Content

The species of Parmelia genus have long been used in Indian folk medicine for the treatment of bronchitis, ulcers, furunculosis, cardiovascular diseases, urolithiasis, amenorrhea, and also at infectious and inflammatory diseases. In Ukraine, the most common lichens of the Parmelia genus are Parmelia sulcata Tailor and Parmelia vagans Nyl. At the same time, thalli of Parmelia genus lichens belong to the non-officinal and poorly studied types of raw material. The qualitative composition and the quantitative content of phenolic compounds in Parmelia sulcata and Parmelia vagans thalli was studied by HPLC. According to the results of the chromatographic analysis, salazinic, fumaroprotocetraric, usnic acids, chloratranorin and atranorin were identified in both types of raw material studied. In addition, protocetraric acid was identified in Parmelia sulcata thalli. According to the results of the experiment, the total content of identified phenolic compounds in Parmelia sulcata thalli was 2019.71±40.39 g/mol, and in Parmelia vagans thalli it comprised 1754.18±34.77 g/mol. In the thalli of both studied species of Parmelia genus, fumaroprotocetraric acid dominanted by the quantity. This substance was present in Parmelia sulcata thalli in the amount of 474.00±9.00 g/mol, and in Parmelia vagans thalli – 456.21±8.67 g/mol. In addition, a significant amount of chloratranorin (408.79±8.99 g/mol) was present in Parmelia sulcata thalli. Quite a high content of atranorin (393.34±8.65 g/mol) and usnic acid (375.31±7.53 g/mol) were defined in Parmelia vagans thalli. The results obtained can be used in the development of quality control methods for Parmelia sulcata and Parmelia vagans thalli, as well as medicines based on these types of raw materials.

scholarly journals Research in the Development and Validation of the Method of Quantitative Determination of Flavonoids in the Common Sorrel Herba, Gathered in the Altai Territory

2019 ◽  
Vol 8 (2) ◽  
pp. 80-86 ◽  
Author(s):  
G. R. Kutateladze ◽  
L. M. Fedoseeva
Keyword(s):  
Particle Size ◽  
Aluminum Chloride ◽  
Raw Materials ◽  
Alcohol Solution ◽  
Raw Material ◽  
Complexation Reaction ◽  
Optimal Parameters ◽  
Quantitative Content ◽  
Development And Validation

Introduction. Common sorrel (Rumex acetosa L.) is a biennial herb from the Buckwheat family (Polygonaceae L.). In our previously studies of phenolic compounds composition of alcohol extraction and ethereal, ethyl acetate, butanol fractions of common sorrel herba and flavonoids of the flavonol group was found. From the literature sources it is known that flavonoids are one of the groups of biologically active compounds with anti-inflammatory action. In this regard, the actual task is to assess the quantitative content of flavonoids in common sorrel herba.Aim. Is the development and validation of a method for the quantitative determination of flavonoids in common sorrel herba.Materials and methods. It has been established that the flavonoid complex of common sorrel herba includes rutin, therefore, the reference sample (RS) rutin was used as a standard for calculating the amount of flavonoids. Alcohol extract of common sorrel herba and a solution of rutin RS were prepared. The complexation reaction with aluminum chloride was carried out. The resulting solutions were investigated by the method of differential spectrophotometry. The spectral characteristics of the test and standard samples were compared. Then we studied the effect of extraction conditions on the yield of flavonoids from the raw material: the extractant, the particle size of the raw material, the ratio of «raw material – extractant», temperature, frequency and duration of extraction. Purified water and ethyl alcohol of various concentrations (20%, 40%, 70%, 90%) were used as the extractant. Next, carried out the selection of the optimal conditions for the complexation reaction (the complexation reaction time, the ratio of «aliquot – aluminum chloride alcohol solution»). The method was validated according to GPM.1.1.0012.15 of the State Pharmacopoeia (SF) XIII edition and generally accepted methods for the following indicators: specificity, analytical field, linearity, accuracy, precision.Results and discussion. The optimal parameters for extracting flavonoids from raw materials were determined (threefold extraction with ethyl alcohol 70% in a water bath, the ratio of «raw material – extractant» – 1:30 for 30 minutes, the particle size of the raw material – 2.0 mm). The conditions for the complexation reaction were selected (the ratio «aliquot: aluminum chloride alcohol solution» – 1: 2.5, the complexing agent – aluminum chloride solution 5% alcohol, the appearance of a stable solution color after 40 minutes). When carrying out the validation of the developed method, it was established that the validation characteristics under study are within the acceptance criteria. When analyzing the raw materials harvested in the Altai Territory in different years, it was found that the content of flavonoids in common sorrel herba ranges from 0,596 to 0,632%.Conclusion. The optimal parameters of extraction of flavonoids from raw materials were determined, the conditions for the complexation reaction were selected, and the developed method was validated. The quantitative content of flavonoids in terms of rutin in sorrel sour grass harvested in the Altai Territory in different years has been established.

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