Blood in psoriasis. Engman, Davis, Reinsh (Diss., 1921)

1923 ◽  
Vol 19 (4) ◽  
pp. 103-103
Author(s):  
E. Korneychik
Keyword(s):  
Leukocyte Count ◽  
Erythrocyte Count ◽  
Total Leukocyte Count ◽  
Normal Limits ◽  
Transient Decrease

The author concludes that Hb content in psoriasis is sometimes decreased, especially in the rash period, erythrocyte count is usually normal, but sometimes there is a transient decrease in the rash period, total leukocyte count is within normal limits.

scholarly journals Effect of garlic and vitamin B-complex in lead acetate induced toxicities in mice

1970 ◽  
Vol 6 (2) ◽  
pp. 203-210 ◽  
Author(s):  
MSH Khan ◽  
M Mostofa ◽  
MS Jahan ◽  
MA Sayed ◽  
MA Hossain
Keyword(s):  
Cell Volume ◽  
Packed Cell Volume ◽  
Lead Acetate ◽  
Leukocyte Count ◽  
Erythrocyte Count ◽  
Total Leukocyte Count ◽  
Vitamin B ◽  
Group B ◽  
Haemoglobin Content ◽  
Serum Glutamate

The experiment was performed on 25 adult mice, (Swiss albino), weighing about 25 gm, maintained on standard pellet diet and drinking water ad libitum. All the mice were randomly divided into five equal groups (5x5). Each group comprised of five mice was marked as group A, B, C, D and E. In the present study an attempt has been taken to study the effect of Garlic and vitamin B-complex in lead induced toxicities in mice with the observation of some parameters as toxic signs and body weight, some haematological parameters like total erythrocyte count (TEC), total leukocyte count (TLC), haemoglobin content (Hb%) and Packed cell volume (PCV), some biochemical parameters such as serum glutamate pyruvate transaminase SGPT/ALT, Serum glutamate Oxaloacetate transaminase (SGOT/AST) and postmortem changes in mice. An attempt was also made to estimate the residual deposition of lead in body tissues i.e. blood, liver, kidney, brain and bone in mice. Mice treated with lead acetate showed severe toxic signs and significantly reduced total erythrocyte count, total leukocyte count, haemoglobin content and packed cell volume and significant elevation of SGPT and SGOT. But in case of mice treated by lead acetate along with Garlic and vitamin B-complex showed almost normal levels of haematological and biochemical parameters. From this experiment it is revealed that Garlic and vitamin B-complex has protective and curative effect in lead toxicity. The mean body weight of mice of group B (only lead acetate) was significantly (p < 0.01) decreased, in comparison with the other treated groups. Lead acetate group also significantly reduced (p < 0.01) total erythrocyte count, packed cell volume and hemoglobin content was on 42 days of treatment. SGPT and SGOT were significantly elevated in all treated groups in comparison with control group. The liver of the mice of group B were blackish discoloration and enlarged. The significant reduction of lead in blood, liver and kidney was found in group E < C< D in comparison to group B (lead treated). The order of effectiveness was Garlic + Vitamin B- complex > Garlic > Vitamin Bcomplex. Key words: Garlic, vitamin B-complex, lead acetate, mice   doi: 10.3329/bjvm.v6i2.2337 Bangl. J. Vet. Med. (2008). 6 (2): 203-210

scholarly journals Hematological Value of Captive Elephants (Elephas maximus) Around Chitwan National Park, Sauraha, Nepal

2021 ◽  
Author(s):  
Roshan Ghimire ◽  
Sagar Regmi ◽  
Rakshya Shrestha ◽  
Amir Sadaula ◽  
Janardan Dev Joshi
Keyword(s):  
National Park ◽  
Leukocyte Count ◽  
Hematological Parameters ◽  
Research Work ◽  
Health Condition ◽  
Erythrocyte Count ◽  
Total Leukocyte Count ◽  
Major Work ◽  
Significant Difference ◽  
Chitwan National Park

Abstract Veterinary hematology serves as an important screening procedure to assess general health condition, diagnosis, and treatment of disease. The study was aimed to interpret and establish a set of hematology reference range for Asian elephants kept under private and government facilities of Nepal as no major work has been done till now. Blood samples from 50 elephants around Chitwan National Park, Sauraha was collected and hematological parameters like total erythrocyte count and total leukocyte count were determined. The results showed that the majority of hematological value was in line with the value previously published by different authors. The mean erythrocyte and leukocyte count was reported as 3.32 ±0.93 ×10^6 cell/µL and 10448±335.49 cells/ µL respectively. No sex-associated significant difference was observed in the case of total erythrocyte count whereas total leukocyte counts varied significantly within sex. Our finding revealed no significant difference in hematological parameters between governmental and privately owned elephants. The hematological value of our study can be used as a reference value for assessing the health condition of elephants in Nepal. Further research work should be conducted to evaluate the factors affecting hematological parameters.

scholarly journals Effectiveness of Potassium Diformate on Feed to Improve Immune Performance of Goldfish (Carassius auratus L.)

2020 ◽  
pp. 24-33
Author(s):  
Ayi Yustiati ◽  
Rima Tri Wahyuni ◽  
Achmad Rizal ◽  
Ibnu Bangkit Bioshina Suryadi
Keyword(s):  
Survival Rate ◽  
Red Blood Cells ◽  
Clinical Sign ◽  
Blood Cells ◽  
Carassius Auratus ◽  
Leukocyte Count ◽  
White Blood Cells ◽  
Erythrocyte Count ◽  
Total Leukocyte Count ◽  
Goldfish Carassius Auratus

This research aims to determine the optimum potassium diformate (KDF) dosage which was added to feed to increase the immune status of goldfish (Carassius auratus L). This study was conducted from September 31 - November 15, 2019 at the Laboratory of Aquaculture and Molecular Biotechnology Laboratory of the Faculty of Fisheries and Marine Sciences, University of Padjadjaran. The research method used is the experimental Complete Random Design (CRD) with 4 treatments and 3 replications. The treatments are A (without KDF/control), B (0.1% KDF), C (0.3% KDF) and D (0.5% KDF). The observed parameters are survival rate, total leukocyte count (white blood cells), total erythrocyte count (red blood cells) and gross clinical sign. Observations were made after 30 days of KDF and post-test challenge by Aeromonas hydrophila for 14 days. Data on the number of total leukocyte count and total erythrocyte count were analyzed using F test and Duncan's advanced test at a 95% confidence level, while the gross clinical sign data were analyzed descriptively. The results showed that the KDF 0.3% was the optimum dose and was very effective in optimizing the performance of the goldfish immune system optimally, seen from the number of white blood cells and red blood cells which experienced the highest increase of 23.48% and 9.30%. After the challenge test, fish that were given KDF 0.3% had the highest survival rate of 46.67%. In addition, the process of recovering the number of white blood cells and red blood cells can be faster than other treatments, with a value of 12.85×104 cells mm3-1 and 0.96×106 cells mm3-1, marked also by the healing of clinical symptoms in the morphology of goldfish.

scholarly journals Immune function during pregnancy varies between ecologically distinct populations

2020 ◽  
Vol 2020 (1) ◽  
pp. 114-128
Author(s):  
Carmen Hové ◽  
Benjamin C Trumble ◽  
Amy S Anderson ◽  
Jonathan Stieglitz ◽  
Hillard Kaplan ◽  
...  
Keyword(s):  
Leukocyte Count ◽  
Total Leukocyte Count ◽  
Future Research ◽  
Differential Leukocyte Count ◽  
Ecological Conditions ◽  
Trade Offs ◽  
The Usa ◽  
Immunological Changes ◽  
Fetal Antigens ◽  
Pathogen Exposure

Abstract Background and objectives Among placental mammals, females undergo immunological shifts during pregnancy to accommodate the fetus (i.e. fetal tolerance). Fetal tolerance has primarily been characterized within post-industrial populations experiencing evolutionarily novel conditions (e.g. reduced pathogen exposure), which may shape maternal response to fetal antigens. This study investigates how ecological conditions affect maternal immune status during pregnancy by comparing the direction and magnitude of immunological changes associated with each trimester among the Tsimane (a subsistence population subjected to high pathogen load) and women in the USA. Methodology Data from the Tsimane Health and Life History Project (N = 935) and the National Health and Nutrition Examination Survey (N = 1395) were used to estimate population-specific effects of trimester on differential leukocyte count and C-reactive protein (CRP), a marker of systemic inflammation. Results In both populations, pregnancy was associated with increased neutrophil prevalence, reduced lymphocyte and eosinophil count and elevated CRP. Compared to their US counterparts, pregnant Tsimane women exhibited elevated lymphocyte and eosinophil counts, fewer neutrophils and monocytes and lower CRP. Total leukocyte count remained high and unchanged among pregnant Tsimane women while pregnant US women exhibited substantially elevated counts, resulting in overlapping leukocyte prevalence among all third-trimester individuals. Conclusions and implications Our findings indicate that ecological conditions shape non-pregnant immune baselines and the magnitude of immunological shifts during pregnancy via developmental constraints and current trade-offs. Future research should investigate how such flexibility impacts maternal health and disease susceptibility, particularly the degree to which chronic pathogen exposure might dampen inflammatory response to fetal antigens. Lay Summary This study compares immunological changes associated with pregnancy between the Tsimane (an Amazonian subsistence population) and individuals in the USA. Results suggest that while pregnancy enhances non-specific defenses and dampens both antigen-specific immunity and parasite/allergy response, ecological conditions strongly influence immune baselines and the magnitude of shifts during gestation.

scholarly journals The mongolian gerbil: qualitative and quantitative aspects of the cellular blood picture

1975 ◽  
Vol 9 (4) ◽  
pp. 283-287 ◽  
Author(s):  
Walter G. Dillon ◽  
Chester A. Glomski
Keyword(s):  
Haemoglobin Level ◽  
Cell Volume ◽  
Mongolian Gerbil ◽  
Leukocyte Count ◽  
Absolute Number ◽  
Total Leukocyte Count ◽  
Red Cell ◽  
Blood Picture ◽  
Qualitative And Quantitative ◽  
Circulating Lymphocytes

The gerbil displays sex determined differences in packed red-cell volume, haemoglobin level, total leukocyte count and absolute number of circulating lymphocytes. The erythrocytes demonstrate a prominent polychromasia and frequent occurrence of basophilic stippling.

Outcomes of Peripheral Blood Eosinophilia in Hospitalized Exacerbations of COPD

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Samar El Sharkawy ◽  
Riham Hazem Raafat ◽  
Reem Osama Mohamed Ahmed Qassem
Keyword(s):  
Peripheral Blood ◽  
Diagnostic Performance ◽  
Leukocyte Count ◽  
Airflow Limitation ◽  
Total Leukocyte Count ◽  
Blood Eosinophil ◽  
Copd Exacerbation ◽  
Peripheral Blood Eosinophil ◽  
Copd Exacerbations ◽  
Cutoff Points

Abstract Background The Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines define COPD as a disease state characterized by airflow limitation that is not fully reversible, is usually progressive, and is associated with an abnormal inflammatory response of the lungs to inhaled noxious particles or gases. Objective To identify outcomes of patients with eosinophilic COPD exacerbations requiring hospital admission. Patients and Methods This study is a prospective cohort study that was conducted on two groups of total 60 patients recruited from Ain Shams University hospitals between October 2019 and July 2020. Group 1: Eosinophilic COPD exacerbation if the peripheral blood eosinophil on admission is ≥ 200 cells/µL and/or ≥2% of the total leukocyte count Group 2: Non-eosinophilic COPD exacerbation if the peripheral blood eosinophil on admission is &lt; 200 cells/µL and/or &lt; 2% of the total leukocyte count. Results There was significant high diagnostic performance in predicting readmission at 6-month among eosinophilic group. Eosinophils count, percent (%) and NLR cutoff points had high characteristics (highest in NLR ≥3.1 at discharge) in predicting readmission at 6-month among eosinophilic group. Diagnostic performance of Eosinophils count, percent (%) and NLR were assessed. Eosinophils count, percent (%) and NLR had significant high diagnostic performance in predicting readmission at 6-month among eosinophilic group. Eosinophils count, % and NLR cutoff points had high characteristics (highest in NLR ≥2.1 at discharge) in predicting readmission at 6month among non-eosinophilic group. Conclusion Eosinophils can be used as a prognostic marker in non-infective COPD exacerbations. Validity of eosinophil count and percent as a prognostic parameter in COPD exacerbation can be increased by combining with other parameters for example NLR.

Utility of Blood Markers in Early Prediction of Bacteraemia in Acute Febrile Paediatric Patients – An Observational Cohort Study in a Tertiary Care Hospital of North India

2021 ◽  
Vol 8 (28) ◽  
pp. 2526-2531
Author(s):  
Rabindra Bhunia ◽  
Bindu T. Nair ◽  
Vandana Negi
Keyword(s):  
Tertiary Care Hospital ◽  
Leukocyte Count ◽  
Tertiary Care ◽  
North India ◽  
Total Leukocyte Count ◽  
Care Hospital ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Neutrophil Percentage ◽  
Observational Cohort

BACKGROUND Bacteraemia is a common cause of children presenting to the paediatric emergency with acute febrile illness. Blood cultures remain the gold standard for detection of bacteraemia but the positivity is low and also takes time to show positive results. A rapid and reliable biomarker like procalcitonin (PCT), C-reactive protein (CRP), total leucocyte count (TLC), and neutrophil-lymphocyte count ratio (NLCR) can be used to identify febrile children with greater risk for bacteraemia or serious bacterial infections. This would be very helpful to start early treatment of bacteraemia with antibiotics. METHODS The study was an observational cohort study conducted in the Department of Paediatrics of a tertiary care hospital in North India in children between age group 6 months to 12 years presenting with fever of > 100.4° F for 2 - 7 days. Blood samples were sent for PCT, CRP, TLC, NLCR and blood cultures. RESULTS The most sensitive biomarker was total leukocyte count (47.36 %) followed by the neutrophil percentage (26.32 %), C-reactive protein (21.05 %), and procalcitonin (15.79 %). The most specific biomarker was procalcitonin (75.14 %) followed by C-reactive protein (58.56 %), neutrophil percentage (22.65 %) and total leukocyte count (11.05 %). The only biomarker that was statistically significant between the bacteraemia and non-bacteraemia group in the present study was total leukocyte count (P – value < 0.05). CONCLUSIONS The sensitivity and specificity of each single biomarker is low and hence these cannot be used singly to predict bacteraemia. There should be a combination of biomarkers with adequate sensitivity and specificity that can be used to create an algorithm to aid in diagnosis and prognostication. KEYWORDS Procalcitonin, C-Reactive Protein, Blood Culture, Acute Febrile Patient

scholarly journals CORRELATION OF TOTAL LEUKOCYTE COUNT AND PLATELETS WITH THE RECOVERY PHASE IN CHILDREN WITH DENGUE ADMITTED IN AN URBAN TERTIARY CARE CENTER

2019 ◽  
Vol 6 (6) ◽  
pp. 295-299
Author(s):  
Nishikant Kotwal ◽  
Milind Mandlik ◽  
Sachin Daharwal ◽  
Kamble Taposhi ◽  
Abhishek Madhura ◽  
...  
Keyword(s):  
Leukocyte Count ◽  
Care Center ◽  
Tertiary Care ◽  
Recovery Phase ◽  
Total Leukocyte Count ◽  
Tertiary Care Center

scholarly journals Evaluation of Procalcitonin (PCT) As a Marker of Infection in Early Post Living Donated Liver Transplant Period.

2021 ◽  
Author(s):  
Eman Ibrahim El-Desoki Mahmoud ◽  
Mohammad A. Algendy ◽  
Adel M. Al-Ansary ◽  
Maissa K. Noaman
Keyword(s):  
Liver Transplantation ◽  
Clinical Course ◽  
Leukocyte Count ◽  
Demographic Data ◽  
Positive Culture ◽  
Infectious Complications ◽  
Total Leukocyte Count ◽  
Solid Organ ◽  
Single Center ◽  
Cutoff Value

Abstract Background: Procalcitonin (PCT) has been increasingly used as a biomarker of bacterial infection and as a tool to guide antimicrobial therapy. Despite its increased use, data in patients with solid organ transplants are limited. The study aim is to assess the frequency of rising procalcitonin associated with infectious complications in immunosuppressed living donated liver transplantation.Methods: A single center, retrospective observational study. Preoperative patients' demographic data, operative, anesthetic data and postoperative clinical course are analyzed till discharge from intensive care unit.Results: Sixty patients were classified according to the culture results' into a positive culture group & a negative one, then following up sepsis variables in each group. Total leukocyte count (TLC) and procalcitonin (PCT) were high in the positive culture group in the first 4 and 5 days respectively and was statistically significant (P-value < 0.05).PCT at a cutoff value ≥ 9ng/ml had higher specificity, especially on day three postoperative (90.7%). The TLC cutoff value of ≥ 17.3/mm3on day one; had the specificity of > 90%. Conclusions: following up PCT level on day one with TLC is essential and will help to detect sepsis and guide early antimicrobial initiation post liver transplantation.Trial registration: NHTMRI, NCT03389360. Registered 7 February, 2018,https://register.clinicaltrials.gov/prs/app/action/SelectProtocol?sid=S0007O6F&selectaction=Edit&uid=U0003W0U&ts=2&cx=fwyacz

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