Incidence of thyroid malignancies in Baku

Aim. To study the epidemiological situation of the incidence of thyroid cancer in Baku during the period 2012-2016. Methods. The basis for conducting the present study was statistical reporting form No. 7 of the Ministry of Health of the Republic of Azerbaijan for the period 2012-2016. 355 patients were examined who were further divided into 2 age groups: 0-17 years (children) and 18 years and older (adults). To assess the epidemiological situation, extensive parameter (disease distribution), intensive (incidence), prevalence of thyroid malignancies, overall mortality rate and lethality, 5-year survival and cancer aggressiveness were used. Results. Analysis of the incidence of thyroid malignancies in Baku during the period 2012-2016, revealed an increase in incidence, especially in female patients. During the study period, incidence of thyroid cancer among males was 1.5-1.6 per 100 000, and among females - 2.5-4.2 per 100 000. Prevalence during the study period among males increased by 1.7 times and by 2.3 times among females. The peak morbidity of thyroid cancer among females was in the age group of 30-39 years (1.8 per 100 000) and 50-59 years (2.2 per 100 000), and among males the standardized index for all age groups was relatively stable (0.3 per 100 000). Conclusion. The assessment of incidence of thyroid malignancies among the population of Baku during the period 2012-2016 revealed its increase, especially among the female population.

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Morphological and Prognostic Characteristics of Breast Cancer in Women Living in the Sakha Republic (Yakutia)

International Journal of Biomedicine ◽

10.21103/article11(2)_oa13 ◽

2021 ◽

Vol 11 (2) ◽

pp. 201-205

Author(s):

Maria Kirillina ◽

Irina Kononova ◽

Sargylana Sofronova ◽

Petr Ivanov ◽

Aytalina Golderova

Keyword(s):

Breast Cancer ◽

Age Groups ◽

Staging System ◽

Cancer Staging ◽

Tnm Staging ◽

Age Group ◽

Morphological Examination ◽

Female Population ◽

Tnm Staging System ◽

The Republic

Background: This article presents the results of the analysis of the clinical and morphological examination of breast cancer (BC) in women of the Republic of Sakha (Yakutia) (RS(Y)). Methods and Results: The object of the study was fragments of breast tissue from 294 women who underwent surgical treatment and/or needle biopsy. By ethnicity, there were 118(40.1%) women of indigenous nationalities and 176(59.9%) women of non–indigenous nationalities. The greatest number of cases of BC was registered in the age group of 50-59 (32.6%). The age group of 40-49 was in second place (20.4%). Among the indigenous population, women in the age groups of 40-49 years (23.7%) and 50-59 years (26.3%) predominated. The age groups of 50-59 years (36.9%) and 60-69 years (22.2%) predominated among the non-indigenous women. Tumors with a size of 2 cm to 5 cm prevailed; they were detected in 185(62.9%) women. Tumors with a spread to the chest wall and skin develop more often in women of non-indigenous nationalities (15.9% of cases), than in women of indigenous nationality (6.8% of cases). Regardless of ethnicity, the most common histological form of BC in women of the RS(Y) was infiltrative ductal cancer (65.3%). Cancer staging according to the TNM staging system showed that n the age group of women under 39 years, Stage IIIB+IIIC (43.2%) was most often registered (p=0.01), while in other age groups, Stage IIA (32.4%) was more often noted. Conclusion: Our findings suggest that further investigation of the peculiarities of the course of BC in the female population of Yakutia would lead to much improved methods of diagnosis and treatment.

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The Incidence of Thyroid Cancer in England and Wales over A Ten-Year Period

Bengal Journal of Otolaryngology and Head Neck Surgery ◽

10.47210/bjohns.2017.v25i1.103 ◽

2017 ◽

Vol 25 (1) ◽

pp. 8-11

Author(s):

Louise Marie Evans ◽

Michael Stechman ◽

David Owens

Keyword(s):

Thyroid Cancer ◽

Age Groups ◽

Ageing Population ◽

Age Group ◽

Thyroid Cancers ◽

England And Wales ◽

Patient Demographics ◽

The Usa ◽

Imaging Patient ◽

Overall Mortality

Introduction The incidence of thyroid cancer has increased worldwide, whether a real or apparent increase is debated. Literature from the USA suggests greater diagnostic scrutiny, environmental and genetic factors may all play a part. This increase will result in a greater number of referrals for surgical assessment. This study examined the trend in incidence of thyroid cancer in England and Wales. Materials and Methods A retrospective study, using the HES database over the period 2000-2010. Data were extracted of all newly diagnosed thyroid cancers in England and Wales and the age at diagnosis. Data were examined for the change in incidence of thyroid cancer diagnosis dependent on the age group of the patient using the linear regression model. Results 45411 patients were identified. In England the incidence of thyroid cancer rose from 5.7/100,000 of the population in 2000 to 9.9/100,000 in 2010 and in Wales it rose from 3.5/100,000 in 2000 to 7.5/100,000. There was a statistical increase (P≤0.02) (t-stat >2) in the diagnosis of thyroid cancers across all age groups with exception of the 0-14 age group (P>0.5). Conclusion There has been a statistical increase in the incidence of thyroid cancer. This is likely to impact on hospitals and cancer service resources. An increase in surgical demand and the coinciding ageing population highlights the importance of further investigation into the etiology, use of imaging, patient demographics, histology and overall mortality of this patient group.

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Lower limb amputations in Southern Finland 1984-1985

Prosthetics and Orthotics International ◽

10.3109/03093648809079386 ◽

1988 ◽

Vol 12 (1) ◽

pp. 9-18 ◽

Cited By ~ 50

Author(s):

T. Pohjolainen ◽

H. Alaranta

Keyword(s):

Lower Limb ◽

Age Groups ◽

Lower Limbs ◽

Amputation Rate ◽

Common Site ◽

Finnish Population ◽

Elderly Age ◽

Epidemiological Situation ◽

Made In ◽

Overall Mortality

To assess the current epidemiological situation concerning lower limb amputations in southern Finland the data on all amputations made in the catchment area of the Helsinki University Central Hospital were analysed for the period 1984-85. During the two-year period, 880 amputations of lower limbs were performed on 705 patients. The amputation rate was 32.5 per 100,000 inhabitants in 1984 and 28.1 in 1985. Patients requiring amputation were arteriosclerotics in 43.1 per cent, and diabetics in 40.7 per cent. Diabetics underwent amputation 3 years younger on average than the arteriosclerotics. The most common site of unilateral amputations was above-knee (42.0 per cent) followed by below-knee (27.7 per cent) and toe amputations (22.2 per cent). The level of amputation tended to become more proximal with increasing age of the patients. The overall mortality figure during three postoperative months was 27.0 per cent. Amputation incidence increased sharply with increasing age. On the base of predictions, the overall age structure of the Finnish population will shift upward causing an increase in the proportion of elderly age groups. A 50% increase in amputation rate is expected in Finland within the next 20-30 years.

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The green autofluorescence intensity and asymmetry of older men is significantly higher than those of older women in their fingernails and certain regions of skin

10.1101/509562 ◽

2019 ◽

Author(s):

Yue Tao ◽

Mingchao Zhang ◽

Danhong Wu ◽

Yujia Li ◽

Weihai Ying

Keyword(s):

Older Women ◽

Diagnostic Method ◽

Age Groups ◽

Older Men ◽

Disease Diagnosis ◽

Health State ◽

Age Group ◽

Female Population ◽

Novel Biomarkers ◽

Left And Right

AbstractOur recent studies have suggested that the patients of multiple diseases have characteristic Pattern of Autofluorescence (AF) in their skin and fingernails, which may become novel biomarkers for both disease diagnosis and evaluation of health state. Since male populations may have higher levels of oxidative stress and inflammation than female population, in our current study we tested our hypothesis that the green AF intensity of older men is higher than that of older women in their fingernails and skin. We found that in both left and right Index Fingernails, the green AF intensity of the men of both the age group of 61 - 70 years of old and the age group of 71 - 80 years of old is significantly higher than that of the women of the same age groups. At both left Dorsal Centremetacarpus and left Centremetacarpus, the green AF intensity of the men at the age between 71 - 80 years of old is also significantly higher than that of the women of the same age group. Moreover, in Index Fingernails, Dorsal Centremetacarpus and Centremetacarpus, the green AF asymmetry of the older men of certain age groups is significantly higher than that of the women of the same age groups. Collectively, our study has provided the first evidence indicating the gender difference between the green AF intensity and asymmetry of older men and those of older women in their fingernails and certain regions of skin, which is valuable for establishing the AF-based diagnostic method.

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A herd immunity to measles and rubella viruses in the population of the Republic of Serbia

Russian Journal of Infection and Immunity ◽

10.15789/2220-7619-ahi-1496 ◽

2021 ◽

Vol 11 (1) ◽

pp. 171-176

Author(s):

M. A. Bichurina ◽

S. Filipovic-Vignjevic ◽

A. Yu. Antipova ◽

M. Bancevic ◽

I. N. Lavrentieva

Keyword(s):

Measles Virus ◽

Herd Immunity ◽

Age Groups ◽

Age Group ◽

Igg Antibodies ◽

Mmr Vaccine ◽

Igg Antibody ◽

Group I ◽

Study Results ◽

The Republic

According to the WHO Strategic Plan, measles should be eradicated in 2020 in the five WHO Regions including European Region. However, large measles outbreaks are being periodically registered in diverse European countries. In the Republic of Serbia (SRB), 5,076 measles cases were detected in 2018, among which 15 cases were fatal.Aim of the study was to examine herd immunity to measles and rubella viruses in the population of the Republic of Serbia.Materials and methods. Blood serum samples obtained in 2018 and 2019 from conditionally healthy residents of the Republic of Serbia were tested for the presence of IgG antibodies to measles and rubella viruses in five age groups: I — children from 2 to 6 years old, II — children from 8 to 14 years old, III — 15 to 24 years old, IV — 25 to 49 years old and V — over 50 years old. A total of 1000 samples were obtained, 200 sera in each group. Enzygnost® Anti-Measles virus/IgG and Enzygnost® Anti-Rubella virus/IgG ELISA test systems (Siemens Healthcare Diagnostics Products GmbH, Germany) were used according to the manufacturer's instructions.Results. Overall, around 23.0% and 33.7% of the surveyed persons had no or low level of anti-measles IgG antibody (≥ 275.0 — ≤ 1000.0 IU/1). In age group I, 60% children contained no or “low” anti-measles antibodies titer (29.5% and 30.5%, respectively). In addition, low antibody titer level was mainly detected in individuals from age group II and III (p < 0.05). A third of children under 8—14 contained high IgG-antibodies titer against measles (> 3000.0 IU/l) that might serve as an evidence that such subjects recently recovered after measles. Similar results were obtained for IgG antibodies to rubella in the same age groups.Discussion. The study results evidence about altered routine immunization against measles and rubella in children aged 12—15 months (first vaccination) and those at age of 6—7 years (revaccination) with MMR vaccine. The data obtained correlate with official data on coverage with measles and rubella vaccines in the Republic of Serbia.

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Age and Gender Specific Lung Cancer Incidence and Mortality in Hungary: Trends from 2011 Through 2016

Pathology & Oncology Research ◽

10.3389/pore.2021.598862 ◽

2021 ◽

Vol 27 ◽

Author(s):

Lilla Tamási ◽

Krisztián Horváth ◽

Zoltán Kiss ◽

Krisztina Bogos ◽

Gyula Ostoros ◽

...

Keyword(s):

Lung Cancer ◽

Age Groups ◽

Age Group ◽

Lung Cancer Incidence ◽

Age And Gender ◽

Female Population ◽

Incidence And Mortality ◽

Icd 10 ◽

And Gender ◽

Gender Specific

Objective: No assessment was conducted describing the age and gender specific epidemiology of lung cancer (LC) prior to 2018 in Hungary, thus the objective of this study was to appraise the detailed epidemiology of lung cancer (ICD-10 C34) in Hungary based on a retrospective analysis of the National Health Insurance Fund database.Methods: This longitudinal study included patients aged ≥20 years with LC diagnosis (ICD-10 C34) between January 1, 2011 and December 31, 2016. Patients with different cancer-related codes 6 months before or 12 months after LC diagnosis or having any cancer treatment other than lung cancer protocols were excluded.Results: Lung cancer incidence and mortality increased with age, peaking in the 70–79 age group (375.0/100,000 person-years) among males, while at 60–69 age group for females (148.1/100,000 person-years). The male-to-female incidence rate ratio reached 2.46–3.01 (p < 0.0001) among the 70–79 age group. We found 2–11% decrease in male incidence rate at most age groups, while a significant 1–3% increase was observed in older females (>60) annually during the study period.Conclusion: This nationwide epidemiology study demonstrated that LC incidence and mortality in Hungary decreased in younger male and female population, however we found significant increase of incidence in older female population, similar to international trends. Incidence rates peaked in younger age-groups compared to Western countries, most likely due to higher smoking prevalence in these cohorts, while lower age LC incidence could be attributed to higher competing cardiovascular risk resulting in earlier mortality in smoking population.

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Morphological Aspects of Proximal Humerus Fractures in Different Age Groups

Creative Surgery and Oncology ◽

10.24060/2076-3093-2019-9-4-247-253 ◽

2020 ◽

Vol 9 (4) ◽

pp. 247-253

Author(s):

V. V. Gainullin ◽

Т. B. Minasov ◽

M. M. Bagautdinov ◽

A. А. Akhmeldinova ◽

E. R. Yakupova ◽

...

Keyword(s):

Bone Metabolism ◽

Proximal Humerus ◽

Bone Fractures ◽

Age Groups ◽

Proximal Humerus Fractures ◽

Age Group ◽

Morphological Aspects ◽

Republic Of Bashkortostan ◽

Humerus Fractures ◽

The Republic

Introduction. Fracture of the proximal humerus is a common injury that accounts for up to 12 % of all bone fractures and up to 65 % of humeral fractures. 13 % to 16 % of fractures in this segment are multi-fragment with bone impression. This significantly complicates the task of internal fixation. This study aims to analyze the gender and age group distribution of patients with proximal humerus fractures, and morphological aspects of these injuries.Materials and methods. This paper presents a retrospective analysis of the epidemiological and morphological parameters of patients treated surgically for proximal humerus injuries at the Department of Traumatology and Orthopedics of the State Regional Clinical Hospital of the Republic of Bashkortostan № 1 in the city of Oktyabrsky in 2010–2016. The total of 191 patients were included in the study, 121 (63.35 %) females and 70 (36.65 %) males.Results and discussions. A signifi cant increase (more than three times) in the number of proximal humerus fractures was recorded in women in the 50–65 age group and in men in the 55–60 age group. The increase in the incidence of this type of injury does not exceed 22.4 % in comparison to the younger age groups. The increase in the number of injuries in question is undoubtedly due to changes in the bone metabolism in women. The analysis of character and morphology of fractures in women of older age groups indicates a greater prevalence of unstable injury of type 1.1.B and 1.1.C according to AO/ASIF classifi cation, which, again, is due to the demineralization of the segment determined by systemic metabolic abnormalities. The fi ndings indicate the need for perioperative monitoring of the bone metabolism parameters.Conclusion.The morphology and types of fractures depend on a patient’s age and bone quality. A signifi cant increase in this pathology in women of perimenopausal age refl ects changes in bone metabolism.

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1295. Mortality of Patients with HIV Infection Admitted to the Intensive Care Unit: A 16-Year Experience

Open Forum Infectious Diseases ◽

10.1093/ofid/ofz360.1158 ◽

2019 ◽

Vol 6 (Supplement_2) ◽

pp. S466-S467

Author(s):

Fernando Rosso ◽

Diana Marcela Martínez-Ruiz ◽

Andres Castro ◽

Luis Gabriel Parra-Lara ◽

Jorge Andrés Hoyos ◽

...

Keyword(s):

Intensive Care Unit ◽

Intensive Care ◽

Life Expectancy ◽

Age Groups ◽

Noncommunicable Diseases ◽

Age Group ◽

Icu Mortality ◽

Hiv Patients ◽

Hiv Mortality ◽

Overall Mortality

Abstract Background The life expectancy of HIV patients has increased with antiretroviral therapy which has reduced the incidence of AIDS-associated illnesses. Longer life expectancy increases noncommunicable diseases cases and the demand for intensive care unit (ICU) care. ICU mortality is higher among HIV patients. Information about mortality and other relevant outcomes among HIV patients from developing countries is paramount for benchmarking purposes. This study aimed to evaluate the mortality of patients with HIV/AIDS admitted to the ICU during the years 1999 to 2015. Methods An observational retrospective study was conducted based on episodes of patients admitted to the ICU of the Fundación Valle del Lili from December 1998 to October 2015. The Cochran-Armitage test was used to evaluate the trend of HIV mortality by 4-year periods, considering sex and age groups ( <50 vs. >50 years). The Z test compared the mortality between HIV patients with non-HIV patients in the ICU; also it compared the mortality in HIV patients by sex and age group. Results A total of 53,798 episodes of ICU admissions were analyzed, 0.76% (414) were HIV patients, and of this 78.5% were men. Twenty-three percent were over 50 years old. Overall mortality in the ICU was 9.13%, and the mortality in HIV patients was 22.03%, which was higher when compared with a non-HIV group (9%, P < 0.001). Mortality due to HIV had a statistically significant decreasing trend (P < 0.001), going from 40% between 1999 and 2003 to 18.04% between 2012–2015, this trend was observed among men with HIV (P < 0.001) starting with 43. 5% and ending at 20%, but among women the decreasing trend was not statistically significant (P = 0.62). Mortality for HIV decreased, in the <50 years group: it went from 38. 3% to 18. 6% (P = 0.0003). Furthermore, in patients 50 years and older group mortality went from 50% to 17.9% (P = 0.025). During period 2008–2011, patients 50 years and older had more mortality compared with <50 years group (P = 0.019), but there were no differences by sex in any period. Conclusion This study found a statistically significant trend for mortality decrease over a 16-year period among HIV patients admitted to an ICU from a developing country. Disclosures All authors: No reported disclosures.

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THYROID DISORDERS

The Professional Medical Journal ◽

10.29309/tpmj/2018.25.05.310 ◽

2018 ◽

Vol 25 (05) ◽

pp. 691-695

Author(s):

Shazia Jahan ◽

Abdur Rouf ◽

Sajid Aziz ◽

Muhammad Ateeq

Keyword(s):

Teaching Hospital ◽

Age Groups ◽

Teaching Hospitals ◽

Thyroid Disorders ◽

Multicenter Studies ◽

Female Population ◽

Female Ratio ◽

Nodular Goitre ◽

Surgical Department ◽

Thyroid Malignancies

Objective: to study the spectrum of various thyroid disorders presentingin peripheral teaching hospitals of Gujranwala region. Study Design: Descriptive, Crosssectional, Interventional. Setting: Department of Surgery Islam Teaching Hospital Sialkot &Surgical Department of Aziz Bhatti Shaheed (Teaching) Hospital. Nawaz Sharif medical College,University of the Gujrat. Study Period: February 2011 to June 2016. Results: A total of 236patients of all age groups with thyroid gland disorders were enrolled in this study. Majority ofpatients were of middle age group with mean age of 43+ years. Male to female ratio was 1:4.Nodular thyroid enlargement was the commonest presentation. Solitary thyroid nodule was thecommonest variant of nodular goitre seen in 48.52% cases. Thyroid carcinoma was found in36.45% cases among the nodular goitres. Conclusion: Thyroid disorders are common in hillyareas of Pakistan, more common in female population. High prevalence thyroid malignancy inpopulation of the Gujranwala Division of Central Punjab is an alarming and worrisome finding inour study. Larger multicenter studies are suggested in this particular region to know the exactincidence, predisposing factors/ carcinogens etc if any responsible for thyroid malignancies inthis region.

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Gender and demographic features of the labor market of the Republic of Tuva: trends and prospects

POPULATION ◽

10.19181/population.2021.24.2.11 ◽

2021 ◽

Vol 24 (2) ◽

pp. 120-130

Author(s):

Organa Natsak

Keyword(s):

Labor Market ◽

Age Groups ◽

Female Population ◽

Regional Labor Market ◽

Active Population ◽

Regional Labor ◽

Working Age ◽

The Republic ◽

Gender Profile ◽

Demographic Features

The article analyzes the gender and demographic features of the labor market of the Republic of Tuva: the structure and rate of employment and unemployment in gender dimension and historic retrospect covering the period of Tuva People's Republic (1921-1944), the Soviet and post-Soviet stages of history. On the basis of statistical data it is shown that from 1945 began predominance of female population in the demographic structure of the republic that is characteristic of modern Tuva. The author makes an attempt to give a historic explanation of this turn. The article shows changes in the ratio of male to female population of Tuva from 1931 to 2020 using various statistic sources and data. In the features of the gender profile of the regional labor market, the author identifies demographic, socio-cultural and economic factors determining it, in particular, the reasons for withdrawal of men from the economically active population in certain age groups. The article substantiates the thesis that, despite the steady trend of reducing unemployment in the republic in 2017, 2018, 2019, the issue of male employment remains acute. It also shows the level of demographic burden on the working-age population of the Republic of Tuva connected with the specifics of reproductive behavior of the population of the republic, namely, high birth rates, as well as the emerging trend of increasing the proportion of people over the working age due to the positive dynamics of increasing life expectancy in the republic.

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