scholarly journals Risk factors and clinical features of recurrent stroke in the Tyva Republic

2014 ◽  
Vol 95 (2) ◽  
pp. 199-202
Author(s):  
Kh D Mongush ◽  
A B Ondar ◽  
R Ch Chylbak-ool ◽  
M B Balchir ◽  
Ch O Mongush
Keyword(s):  
Risk Factors ◽  
Family History ◽  
Alcohol Consumption ◽  
Arterial Hypertension ◽  
Recurrent Stroke ◽  
Excessive Alcohol Consumption ◽  
Stroke Group ◽  
History Of ◽  
Excessive Alcohol ◽  
Male Patients

Aim. To determine risk factors and clinical features of the recurrent stroke. Methods. A prospective 3-year cohort study was conducted including 120 patients with stroke admitted to the neurological department of the Republican Hospital №1 of Kyzyl at 2010-2012, 60 of whom had recurrent stroke (group 1), and 60 had primary stroke (group 2). Results. Recurrent stroke was by 16.66% more common in men. The mean age of males having recurrent stroke was younger compared to females (р 0.05). Patients with family history of arterial hypertension in closest relatives were significantly more prevalent among those with recurrent stroke (70 versus 35%, p 0.05). The rate of excessive alcohol consumption was also significantly higher in patients with recurrent stroke (18.33 versus 6.67%, p 0.05). Mortality associated with the recurrent stroke was higher in males of all age groups, difference was statistically significant in male patients over 70 years of age (p 0.05). Combined first 28-day mortality was 26.67% (32 cases), and was higher in patients with primary stroke (p 0.05). Only 21.67% of patients took antihypertensives regularly prior to the primary stroke, among patients with recurrent stroke this share reached 70%. Antiplatelet drugs were taken by 5% of patients prior to the primary stroke, in patients who suffered the stroke the share was higher and reached 53.33%. Conclusion. Family history of arterial hypertension was the most important risk factor for recurrent stroke. Male patients had higher risks of recurrent stroke and fatal outcome, which may be associated with lower drug compliance (including antiplatelet drugs and anticoagulants, antihypertensives) and higher exposure to other risk factors (smoking, excessive alcohol consumption).

scholarly journals Study on Associated Risk Factors of Hypertension at Sipaghat of Sindhupalchowk District, Nepal

2017 ◽  
Vol 1 ◽  
pp. 73-82
Author(s):  
Naresh Manandhar
Keyword(s):  
Risk Factors ◽  
Family History ◽  
Alcohol Consumption ◽  
Lifestyle Modification ◽  
Percent Level ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
History Of ◽  
Family History Of Hypertension ◽  
Associated Risk Factors

Background: Hypertension is a progressive cardiovascular syndrome arising from complex and interrelated etiologies. Males have slightly higher prevalence than female in most of countries of Southeast-Asian region.Objective: The objective of study is to find out prevalence and the risk factors of hypertension at Sipaghat, Sindhulchowk, Nepal.Materials and Methods: A cross-sectional study was conducted at Sipaghat of Sindhupalchowk district in May 2016 and 260 persons were selected randomly. Results: The prevalence of hypertension was higher in male (25.4%) than female (17.4%). Mean age of study population was 42.08 years with standard deviation, 15.95 years. Variables namely age group, smoking, alcohol consumption and family history of hypertension were found to be significant at 5 percent level of significance. Alcohol consumption and smokers have more than two times higher chance of getting hypertension compared to alcohol non-consumer and nonsmoker with 95% confidence intervals were 1.08-4.80 and 1.21-6.10, respectively. Persons with family history of hypertension have 3.8 times more chance of getting hypertension compared to no family history of hypertension with 1.89-7.61 of 95% confidence interval.Conclusion: Lifestyle modification reduces blood pressure which prevents or delays the incidence of hypertension. Hypertension can be controlled and prevented by modifying the lifestyle. People should be advised to avoid modifiable risk factors of hypertension like smoking, consumption of alcohol and physical inactivity through health education programs.Nepalese Journal of Statistics, 2017, Vol. 1, 73-82

Characteristics, management and outcomes of patients with hepatocarcinoma in a low-income country.

2021 ◽  
Vol 39 (15_suppl) ◽  
pp. e16166-e16166
Author(s):  
Jennifer Dominguez ◽  
Bonnie Macario ◽  
Rixci Ramirez ◽  
Mario Daniel Castro
Keyword(s):  
Alcohol Consumption ◽  
Liver Cancer ◽  
Low Income ◽  
Cox Regression ◽  
Target Therapy ◽  
Income Country ◽  
Rank Test ◽  
Excessive Alcohol Consumption ◽  
History Of ◽  
Excessive Alcohol

e16166 Background: Worldwide, every year, there are nearly 905,000 patients diagnosed with liver cancer; it is the sixth most common malignancy and the third most lethal malignancy. Almost three quarters of new patients live in areas with low and medium-income country. Guatemala has the highest mortality and incidence of liver cancer. Objectives: Describe the clinical characteristics, main risk factors, treatment and outcomes of patients with hepatocarcinoma (HCC) in Guatemala. Methods: A retrospective review was performed among patients with HCC from January 2002 to December 2019 in the Instituto Guatemalteco de Seguridad Social (IGSS). Kaplan Meier curves, Cox regression and log-rank test were used to calculate overall survival (OS) and mortality. Results: 140 patients with HCC were analyzed, 114 women and 26 men with a median age of 60 years (20 - 99), 102 patients (73%) have history of excessive alcohol consumption and 11 (8%) has history of chronic hepatitis B or C virus infection. All of the patients have liver cirrhosis, Child-Pugh A 100 patients (71%), B 34 (24%) and C 6 (5%). 10 patients (7%) have HCC BCLC A, 0 (0%) BCLC B, 121 (81%) BCLC C and 9 (6%) BCLC D. All patients with HCC BCLC A received surgical treatment with a median OS of 123 months (95% CI 89 - 156 p < 0.001). 122 patients (89%) received target therapy with Sorafenib with a median OS of 17 months (95% CI 12 - 21 p < 0.001) and 8 patients (6%) underwent to chemoembolization with a median OS of 32 months (95% CI 12 - 52 p < 0.001). At this time, 111 patients (79%) died from the disease, 11 (8%) are alive with the disease and 8 (6%) are alive without disease. Conclusions: The most frequent risk factor for HCC is the excessive alcohol consumption, survival of patients with HCC are associated with treatment at the beginning of the disease.

scholarly journals Alcoholic Cirrhosis with Zinc and Copper Co-Deficiency

2019 ◽  
Vol 2 (1-3) ◽  
pp. 8-15
Author(s):  
Chanita Unhapipatpong ◽  
Daruneewan Warodomwichit ◽  
Kumutnart Chanprapaph
Keyword(s):  
Alcohol Consumption ◽  
Zinc Deficiency ◽  
Copper Deficiency ◽  
Zinc Supplementation ◽  
Alcoholic Cirrhosis ◽  
Oral Antibiotics ◽  
Excessive Alcohol Consumption ◽  
History Of ◽  
Excessive Alcohol

A 54-year-old Thai female with known alcoholic cirrhosis presented with chronic scaly eczematous patches and plaque for over 1 month. Initially, she was treated with oral antibiotics, but the lesions did not improve. The dermatologic examination and history of alcoholic cirrhosis were compatible with zinc deficiency. Moreover, copper deficiency was found together with zinc deficiency. Excessive alcohol consumption can cause zinc and copper co-deficiency. To avoid aggravated copper deficiency after zinc supplementation, copper and zinc were supplemented together in appropriate proportions. On the 2-week follow-up examination, her clinical outcome improved.

scholarly journals The Risk Factors of Pancreatic Cancer Patients in Dr. Cipto Mangunkusumo National Hospital, Jakarta During 2014-2019

2020 ◽  
Vol 21 (2) ◽  
pp. 120-125
Author(s):  
Kaka Renaldi ◽  
Teddy Septianto ◽  
Dadang Makmun
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Pancreatic Cancer ◽  
Chronic Pancreatitis ◽  
Family History ◽  
Alcohol Consumption ◽  
Cancer Patients ◽  
Obesity And Diabetes ◽  
History Of ◽  
Age Adjusted Rates

Background: Pancreatic cancer is a very rare cancer with age-adjusted rates ranging from about 5 to 10 new cases per 100,000 persons per year. It has one of the worst prognoses of any type of cancer, with a 5-year survival rate of only 4.6%. Several risk factors have been identified, including older age, smoking, familial history of pancreatic cancer, obesity, chronic pancreatitis, diabetes mellitus, and alcohol consumption.Method: This was a descriptive study describing the risk factors of patients who were diagnosed with pancreatic cancer in the period between 1 January 2014 – 1 January 2019 at the Cipto Mangunkusumo National Referral Hospital (RSCM) Jakarta. Data were obtained from the medical records and Endoscopic Retrograde Cholangiopancreatography (ERCP) database from the RSCM Gastrointestinal Endoscopy Center.Results: From January 2014 to January 2019 there were 123 patients with newly diagnosed pancreatic cancer in RSCM. The mean age was 52 years old. The incidence of pancreatic cancer is more common in men (53%) than women (47%). The most common risk factor identified is smoking which was found in 29% of patients, followed by obesity at 27.9% and a history of diabetes mellitus at 19.5%. Risk factors with a fairly low prevalence include alcohol consumption at 9.7% and chronic pancreatitis at 2.4%. No family history of pancreatic cancer is identified in any subject.Conclusion: Smoking, obesity, and diabetes mellitus are common risk factors in pancreatic cancer patients. In contrast, chronic pancreatitis, alcohol consumption, and family history of pancreatic cancer are less commonly identified in patients.

scholarly journals ROLE OF HELICOBACTER PYLORI INFECTION AND LIFESTYLE HABITS IN THE DEVELOPMENT OF GASTRODUODENAL DISEASES IN A POPULATION FROM THE BRAZILIAN AMAZON

2013 ◽  
Vol 50 (3) ◽  
pp. 170-174 ◽  
Author(s):  
Ruth Maria Dias Ferreira VINAGRE ◽  
Adenielson VILAR-e-SILVA ◽  
Amanda Alves FECURY ◽  
Luisa Caricio MARTINS
Keyword(s):  
Risk Factors ◽  
Helicobacter Pylori ◽  
Peptic Ulcer ◽  
Alcohol Consumption ◽  
Eating Habits ◽  
Severe Disease ◽  
Lifestyle Habits ◽  
Excessive Alcohol Consumption ◽  
Excessive Alcohol ◽  
H Pylori

Context Although more than half of the world's population is colonized with Helicobacter pylori, it remains unknown why this organism is able to produce severe disease in some hosts and be innocuous in others. The clinical outcome of infection is determined by several factors, including differences in the host response to bacterial stimulation, specific virulence factors of the organism and environmental influences, or a combination of these factors. Objectives This study compared the prevalence of H. pylori infection and risk factors (infection with CagA+ strains, excessive alcohol consumption, smoking, and inadequate eating habits) between patients with different gastrointestinal disorders and associated these risk factors with the histopathological findings. Methods In a prospective study, samples were collected from 442 patients and a standardized questionnaire regarding lifestyle habits (excessive alcohol consumption, smoking, and eating habits) was applied. The presence of H. pylori and of the cagA gene was investigated by polymerase chain reaction (PCR). Gastric biopsies were obtained for histological assessment. Results The frequency of alcohol consumption, smoking, inadequate diet and infection with CagA+ H. pylori was higher among patients with peptic ulcer and adenocarcinoma when compared to those with gastritis. Gastric inflammation was more pronounced in patients infected with CagA+ strains. Conclusion We conclude that infection with CagA+ H. pylori strains, excessive alcohol consumption, smoking and inadequate eating habits increase the risk of developing peptic ulcer and gastric carcinoma.

scholarly journals Shared Medical and Environmental Risk Factors in Dry Eye Syndrome, Sjogren’s Syndrome, and B-Cell Non-Hodgkin Lymphoma: A Case-Control Study

2019 ◽  
Vol 2019 ◽  
pp. 1-9 ◽  
Author(s):  
Hadas Ben-Eli ◽  
Doron J. Aframian ◽  
Eldad Ben-Chetrit ◽  
Dror Mevorach ◽  
Geffen Kleinstern ◽  
...  
Keyword(s):  
Risk Factors ◽  
Family History ◽  
Alcohol Consumption ◽  
B Cell ◽  
Dry Eye ◽  
Case Control Study ◽  
Case Control ◽  
Non Hodgkin Lymphoma ◽  
History Of ◽  
Control Study

Objectives. To assess whether there are shared exposures associated with Sjogren’s syndrome (SS), dry eye syndrome (DES), and B-cell non-Hodgkin lymphoma (B-NHL), in order to determine whether they are etiologically related. Methods. In a clinic-based case-control study, 702 participants (91 SS, 120 DES, 211 (age and sex frequency-matched) controls, and 280 B-NHL cases) were recruited and interviewed regarding exposures, medical history, and family history. Results. Female predominance was noted in SS (ratio 9.2 : 1). Eye dryness was severest in SS compared to DES and controls (P<0.001). Compared to controls, alcohol consumption was inversely associated with NHL, DES, and SS (odds ratio OR=0.47, 95% confidence interval (CI): 0.31-0.71; OR=0.54, 95% CI: 0.33-0.88; and OR=0.26, 95% CI: 0.14-0.49, respectively), while a previous history of infection requiring hospitalization was positively associated with all three conditions: NHL (OR=1.92; 95% CI: 1.23-2.99), DES (OR=3.29; 95% CI: 1.97-5.47), and SS (OR=4.74; 95% CI: 2.66-8.44). NHL patients were more likely to report first-degree relatives with hematologic cancer, while having first-degree relatives with an autoimmune disease (AID) was associated with SS (OR=5.25; 95% CI: 2.59-10.63) and DES (OR=3.55; 95% CI: 1.83-6.91) compared to controls. Conclusions. Some exposures are associated with all three conditions (such as an inverse association with alcohol consumption and a positive association with serious past infection), while a family history of AID appears to be shared by DES and SS, but not NHL subjects. Shared risk factors for all three conditions indicate possible mutual etiological pathways.

scholarly journals Comparative epidemiology of gestational diabetes in ethnic Chinese from Shanghai birth cohort and growing up in Singapore towards healthy outcomes cohort

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Evelyn Xiu Ling Loo ◽  
Yuqing Zhang ◽  
Qai Ven Yap ◽  
Guoqi Yu ◽  
Shu E Soh ◽  
...  
Keyword(s):  
Risk Factors ◽  
Family History ◽  
Alcohol Consumption ◽  
Gestational Diabetes ◽  
Diagnostic Criteria ◽  
Birth Cohort ◽  
Growing Up ◽  
Ethnic Chinese ◽  
Iadpsg Criteria ◽  
History Of

Abstract Background Gestational diabetes mellitus (GDM) has been associated with adverse health outcomes for mothers and offspring. Prevalence of GDM differs by country/region due to ethnicity, lifestyle and diagnostic criteria. We compared GDM rates and risk factors in two Asian cohorts using the 1999 WHO and the International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria. Methods The Shanghai Birth Cohort (SBC) and the Growing Up in Singapore Towards healthy Outcomes (GUSTO) cohort are prospective birth cohorts. Information on sociodemographic characteristics and medical history were collected from interviewer-administered questionnaires. Participants underwent a 2-h 75-g oral glucose tolerance test at 24–28 weeks gestation. Logistic regressions were performed. Results Using the 1999 WHO criteria, the prevalence of GDM was higher in GUSTO (20.8%) compared to SBC (16.6%) (p = 0.046). Family history of hypertension and alcohol consumption were associated with higher odds of GDM in SBC than in GUSTO cohort while obesity was associated with higher odds of GDM in GUSTO. Using the IADPSG criteria, the prevalence of GDM was 14.3% in SBC versus 12.0% in GUSTO. A history of GDM was associated with higher odds of GDM in GUSTO than in SBC, while being overweight, alcohol consumption and family history of diabetes were associated with higher odds of GDM in SBC. Conclusions We observed several differential risk factors of GDM among ethnic Chinese women living in Shanghai and Singapore. These findings might be due to heterogeneity of GDM reflected in diagnostic criteria as well as in unmeasured genetic, lifestyle and environmental factors.

scholarly journals Pola makan suku asli Papua dan non-Papua sebagai faktor risiko kejadian hipertensi

2014 ◽  
Vol 10 (4) ◽  
pp. 198
Author(s):  
Sarni Rante Allo Bela ◽  
Bambang Djarwoto ◽  
I Made Alit Gunawan
Keyword(s):  
Risk Factors ◽  
Alcohol Consumption ◽  
Sodium Intake ◽  
Health Sector ◽  
Fat Intake ◽  
Chi Square ◽  
Excessive Alcohol Consumption ◽  
High Sodium ◽  
Potassium Intake ◽  
Excessive Alcohol

Background: Hypertension is one of the problems in the medical and public health sector. The prevalence of hypertension in Jayapura City is 23,8%. Hypertensive disease was ranked 6th among the top 10 diseases in Abepura Hospital. The risk factors, a diet containing high fat, high sodium, low potassium and excessive alcohol consumption has contributed to the increasing of blood pressure.Objective: To determine the degree of hypertension difference between Papuans and non-Papuans, and the effect of intake of fat, sodium, potassium and alcohol consumption as risk factors for hypertension in each tribe.Method: The study was an observational analytic with a case-control design. Samples are 248 which is divided in 62 cases and 62 controls on each tribe. Data analysis using the statistical independent t-test, Chi-Square, Mantel Haenzel, Multiple Regression Logistic.Results: Non-Papuan tribes had 1.9 times higher risk of hypertension stage 2. The fat intake of indigenous Papuans (OR=3.250) and non-Papuans (OR=3.275) correlated significantly. Sodium intake significantly associated in indigenous Papuans, but the non-Papuans, have a significant relation (OR=2.531). There was a correlation between potassium intake in indigenous Papuans (OR=2.348), but the non-Papuans, was not. Consumption of alcohol in indigenous Papuans was significantly associated (OR=2.343), but the non-Papuans, was not. Multivariate analysis showed that psychosocial stress, consumption of alcohol, family history of hypertension, and potassium intake were contributing in indigenous Papuans. Intake of fat, sodium intake, and obesity was contributed in non-Papuan tribes. Conclusion: Non-Papuan tribes prone to has hypertension stage 2. In Papuans, fat intake (> 30%), potassium intake (<2000 mg) and excessive alcohol (≥ 2 glasses/day) are risk factors. In the non-Papuan, fat intake (> 30%) and sodium intake (≥ 2300 mg) are risk factors for hypertension.

Sign in / Sign up

Export Citation Format

Share Document