scholarly journals Characteristics of adaptive responses and status of newborns depending on degree of parturient genital colonization with Ur. Urealyticum

2018 ◽  
Vol 35 (6) ◽  
pp. 5-9
Author(s):  
T. A. Melnikova ◽  
M. M. Padrul ◽  
E. S. Gorovits ◽  
G. I. Rabotnikova

Aim. To study the characteristic features of newborn status depending on the level of parturient genital colonization with Ur. urealyticum. Materials and methods. The characteristic features of newborns’ status were studied in 112 puerperas, who by the results of repeated microbiological examination for ureaplasmosis, in the period of 30–34 weeks of pregnancy were divided into 3 groups: group I included 38 persons with negative results of PCR and bacteriology; group II (risk) joined 39 women, infected with Ur. urealyticum to 104 CFU/ml and PCR 5·104 DNA copies per ml; and group III – 35 pregnant women with bacterial inoculation less than 104 CFU/ml. The comparison group – 40 pregnant women, uninfected with ureaplasmas when examined for the first time. Results. In newborn children from puerperas of risk group, Apgar scores at 1 and 5 minutes were statistically significantly lower, than in children, born from mothers of the other groups. In this group, birth of premature newborns and those with hypotrophy as well as newborns with fetal development retardation syndrome were registered significantly more often. Perinatal encephalopathy was detected in 50.0 % of newborns. When discharged from maternal home, nearly a half of infants from this group had no the initially required body mass, but in the other groups there were 2–2.5 times more such newborns. Conclusions. Newborns from mothers infected with Ur. Urealyticum in high, etiologically significant titers, are characterized by decrease in adaptive responses that is proved by Apgar scores and by retarded body mass growth after birth. High level of parturient genital colonization with Ur. urealyticum has a negative effect on the newborns’ health status. Low, etiologically insignificant Ur. urealyticum titers in mothers practically don’t influence the newborns’ health status.

2021 ◽  
Vol 20 (4) ◽  
pp. 64-68
Author(s):  
S.S. Tumanyan ◽  
◽  
S.V. Tumanyan ◽  
E.A. Udovenko ◽  
◽  
...  

Objective. To study the features of adaptive homeostasis in women with normal pregnancy and moderate preeclampsia (MPE). Patients and methods. Sixty-eight pregnant women were under study. General non-specific adaptive responses and adaptive cardiovascular responses were examined in 30 women with normal pregnancy and in 38 women with MPE. Results. Both general and organ adaptive responses were found to have a close correlation with the course of labor, the immediate postpartum period, and perinatal outcomes. Identification of general non-specific adaptive responses in the group of patients with MPE indicated the development of moderate stress response in 37%. Anti-stress responses accounted for 67%, mostly due to the training response. Conclusion. The analysis of comprehensive indicators of systemic and organ adaptation in pregnant women with MPE revealed the maladaptation of their regulatory mechanisms and signs of exhaustion of adaptation and energy reserves. The detected changes in systemic and organ adaptation have a negative effect on pregnancy and perinatal outcomes. Key words: moderate preeclampsia, adaptation, course of labor, prenatal outcomes


Author(s):  
L. V. BAHNIY ◽  
S. N. HERYAK ◽  
N. I. BAHNIY

Today, non-alcoholic fatty liver disease (NAFLD) is a common pathology and pressing problem in pregnant women, especially among overweight, as the incidence of obese women of childbearing age is rapidly increasing. Disorders of lipid metabolism, which is an integral part of this disease, lead to pathological changes in the functional state of the liver, which in turn have a negative impact on pregnancy and lead to the formation of obstetric and perinatal complications. THE AIM OF OUR STUDY was to evaluate the clinical and laboratory markers of liver disorders in pregnant women with NAFLD depending on body mass index. MATERIALS AND METHODS. We’ve examined 98 pregnant women with NAFLD at the stage of non-alcoholic steatohepatitis (NASH) in combination with obesity. The age of the examined women ranged from 21 to 35 years (mean age 30.5 ± 1.5 years). The control group consisted of 30 almost healthy pregnant women. Depending on the body mass index (BMI), all surveyed women are divided into three groups: Group I - overweight pregnant women, Group II - pregnant women with grade I obesity, Group III - pregnant women with grade II obesity. We evaluated the incidence of major clinical complaints and changes in blood biochemical parameters in pregnant women depending on the increasing of BMI. RESULTS. When comparing the clinical manifestations of NAFLD on the stage of NASH in pregnant, the highest frequency is observed in the group of examined women with severe obesity compared with the group of patients with moderate obesity and overweight: symptoms of asthenic syndrome (increased fatigue, sleep disturbances, emotional lability, decreased and increased appetite) in 91.6.0%, 79.1% and 61.5% of patients (p<0.05), manifestations of dyspepsia  (constipation, nausea, flatulence) - in 87.5%, 54% and 34.6% patients (p <0.05), feeling of heaviness or moderate pain in the right hypochondrium - in 62.5% 50% and 30.7% of patients, respectively (p <0.05). CONCLUSIONS. It has been established that pregnant women with non-alcoholic fatty liver disease on the stage of nonalcoholic steatohepatitits have pronounced clinical picture of the disease, which depends on the increase in BMI. It was found that in pregnant women with NAFLD liver dysfunction occurs on the background of grade I obesity, which can be considered as an early marker of steatohepatitis and risk of obstetric complications.


2021 ◽  
Vol 15 (10) ◽  
pp. 3500-3502
Author(s):  
Saeeda Safi ◽  
Umme habiba ◽  
Shandana Mustafa Jadoon ◽  
Umbreen Idrees ◽  
Ayesha Aftab ◽  
...  

Objective: The aim of this study is to compare the vitamin D level among vaccinated and non-vaccinated pregnant women with COVID-19. Study Design: Observational/comparative study Place and Duration: The study was conducted at the department of Gynae and Obs Quaid-e-Azam International Hospital, Islamabad and Qazi Hussain Ahmad Medical Complex, Nowshera for Duration of six months from October 2020 to March 2021. Methods: Total 120pregnant women had coronavirus disease were presented. Informed written consent was taken for details demographics age, gestational age, parity and body mass index. 18-45years was the women ages. Patients were categorized into 2-groups. Group I had 60 vaccinated patients and in group II 60 non-vaccinated pregnant women. Blood sample of all the patients were taken for the level of serum 25-hydroxy vitaminD3 [25 (OH) D3]. Vitamin D deficiency was calculated and compared among both groups. Sufficient serum vitamin D level was considered >30ng/ml. SPSS 23.0 version was used to analyze complete data. Results: In group I age was 28.4±8.55 years with mean BMI 24.08±1.18 kg/m2 and in group II age was 27.41±6.37 years with mean body mass index 23.12±4.42 kg/m2. Mean gestation age in group I was 33.12±9.42 weeks and in group II mean gestational age was 34.07±5.63 weeks. Mean parity in group I was 3.88±7.27 and in group II 4.01±4.14 was mean parity. We found 28 (46.7%) primigravida cases in I-group and 30 (50%) primigravida females in II-group. In group I 51(85%) patients had vitamin D deficiency and in group II 54 (90%) had deficiency of vitamin D. Among 51 deficient women of group I, number of severe deficiency (<10ng/ml) women were 8 (13.3%), deficiency (10-20ng/ml) were 13 (21.7%) and not-sufficient (20-30ng/ml) were 30 (50%) and in group II prevalence of severity (<10ng/ml) patients were 10 (16.7%), deficient cases (10-20ng/ml) were 15 (25%) and not-sufficient cases (20-30ng/ml) were 29 (48.3%). Deficient vitamin D serum levels were 15.01±1.22 in group I and 14.34±4.12 in group II. Conclusion: In this study we concluded that prevalence of vitamin D deficiency was highly among pregnant women and most probably in non-vaccinated pregnant patients but did not find any significantly difference among both groups. Keywords: Pregnancy, COVID-19, Vitamin D, Vaccination


2018 ◽  
Vol 6 (2) ◽  
pp. 154
Author(s):  
Hermin Yulianti ◽  
Fariani Syahrul

Working during pregnancy has negative effect for the health status of pregnant women. Exercises during pregnancy is one of the ways to improve the health status of pregnant women. The aim of research was to analyze the differences of duration and type of childbirth based on the exercises during pregnancy on working mother. This research was an observational analytic study with retrospective cohort design. The exposed population was third trimester of pregnant women who worked and participated in pregnancy exercises > 180 minutes. The non-exposed population was third trimester of pregnant women who worked and participated in pregnancy exercises ≤ 180 minutes. Sample for the exposed group was 30 pregnant women and the non-exposed group was 60 pregnant women. The research analysis was to find the RR value with 95% Confidence Interval (CI). Pregnant women who participated in pregnancy exercises have a short or normal childbirth period 1.543 times than non-participated women. Pregnant women who participated in pregnancy exercises have a normal type of childbirth 1.256 times than non-participated women. There were differences of duration and type of childbirth based on the pregnancy exercises on working mother.


2021 ◽  
Vol 6 (1) ◽  
pp. 113-118
Author(s):  
I. I. Petrashenko ◽  
◽  
T. O. Loskutova ◽  
Zavizion E. M.

Diagnosis and treatment of acute surgical abdominal pathology in pregnant women is still complex and not fully resolved issue. The most frequent reason of urgent surgery in pregnant is acute appendicitis. This pathology remains an urgent problem nowadays. Still there is no consensus on the choice of appendectomy method depending on gestational term. The introduction of endoscopic surgery into widespread clinical practice significantly changed the views on the possibility of using it in pregnant women. But possibility of performing laparoscopy in pregnant women still causes some caution. Moreover, laparoscopic techniques at different stages of pregnancy are far from being improved. Material and methods. The study involved 73 pregnant women with acute appendicitis (group I) and 43 non-pregnant women (group II), who were hospitalized to the clinic. The informativeness of laparoscopic method was studied according to the following criteria: sensitivity (Se), specificity (Sp), accuracy (Ac) and efficiency (De). For each of these criteria was calculated a 95% confidence interval (CI). Results and discussion. Research did not reveal correlation of frequency direct and indirect laparoscopic signs from gestational terms. The frequency of these signs was almost the same in the groups of pregnant and non-pregnant women. The most difficult laparoscopic diagnosis was with catarrhal changes in the wall of appendix, since morphological changes in this form of inflammation extended only to the mucous and submucosal membranes, and macroscopic changes were minimal. Such symptom as the imposition of fibrin in catarrhal appendicitis was absent in all cases. The rest of the signs were observed in all women studied, while macroscopic changes in destructive forms of appendicitis, indicating inflammation, were frequent compared with catarrhal ones. Attention drawn to high parameters of informativeness diagnostic laparoscopy in pregnant women in the first trimester. This is due to the coincidence of clinical and histological diagnoses in this trimester. Considering the number of truly negative results of the study in the II and III trimesters of pregnancy, the indicators of informativeness of laparoscopy did not differ much from the gestational age. Conclusion. Thus, laparoscopy as a diagnostic method for acute appendicitis turned out to be quite informative in both pregnant and non-pregnant women: it allowed confirming or excluding diagnosis of acute appendicitis, it also accurately determined the localization of appendix, choosing correct treatment tactics and safely perform an adequate low-traumatic surgery


1996 ◽  
pp. 13-23
Author(s):  
Mykhailo Babiy

Political ideological pluralism, religious diversity are characteristic features of modern Ukrainian society. On the one hand, multiculturalism, socio-political, religious differentiation of the latter appear as important characteristics of its democracy, as a practical expression of freedom, on the other - as a factor that led to the deconsocialization of society, gave rise to "nodal points" of tension, confrontational processes, in particular, in political and religious spheres.


2018 ◽  
Author(s):  
George Simeakis ◽  
Evangelia Vogiatzi ◽  
Panagiota Konstantakou ◽  
Evangelia Zapanti ◽  
Katerina Saltiki ◽  
...  

2020 ◽  
Vol 98 (3) ◽  
pp. 178-184
Author(s):  
T. V. Chernyakova ◽  
A. Yu. Brezhnev ◽  
I. R. Gazizova ◽  
A. V. Kuroyedov ◽  
A. V. Seleznev

In the review we have integrated all up-to-date knowledge concerning clinical course and treatment of glaucoma among pregnant women to help specialists choose a proper policy of treatment for such a complicated group of patients. Glaucoma is a chronic progressive disease. It rarely occurs among childbearing aged women. Nevertheless the probability to manage pregnant patients having glaucoma has been recently increasing. The situation is complicated by the fact that there are no recommendations on how to treat glaucoma among pregnant women. As we know, eye pressure is progressively going down from the first to the third trimester, so we often have to correct hypotensive therapy. Besides, it is necessary to take into account the effect of applied medicines on mother health and evaluate possible teratogenic complications for a fetus. The only medicine against glaucoma which belongs to category B according to FDA classification is brimonidine. Medicines of the other groups should be prescribed with care. Laser treatment or surgery may also be a relevant decision when monitoring patients who are planning pregnancy or just bearing a child. Such treatment should be also accompanied by medicines.


2020 ◽  
Vol 17 (2) ◽  
pp. 172
Author(s):  
HARMAN AGUSAPUTRA ◽  
MARIA SUGENG ◽  
AYLY SOEKAMTO ◽  
ATIK WULANDARI

<p><strong>Abstract</strong></p><p><strong>Background:</strong> Hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>) as antiseptic has been used frequently to clean woundsin in hospitals and clinics. Hydrogen peroxide has the effectof strong oxidative that can kill pathogens. It can clean up debris and necrotic tissuesin wounds. Hydrogen peroxidealso has hemostatic effect that can help to stop bleeding. Besides antiseptic effects, hydrogen peroxide i s suspected of having negative effect in wound healing. Hydrogen peroxide presumably could cause delayed wound healing by exudate formation and delayed epithelial growth.</p><p><strong>Method</strong>: This study was conducted in the laboratory using 48 white mice that were divided into 2 groups. All the mice were purposely wounded. Afterwards in one group the wounds were clean up using hydrogen peroxide, while in the other group without hydrogen peroxide as control. The wounds of both groups were observed on day 1, day 3 and day 7. On day 1 and day 3, both groups did not show significant difference.</p><p><strong>R</strong><strong>esult</strong> : on day 7 showed that the wound healing in hydrogen peroxide group were delayed. Fifty percent of them had the formation of exudate and 62.5% of them showed delayed epithelial growth.</p><p><strong>Conclusion </strong>: This study could show hydrogen peroxide as wound antiseptic has delayed wound healing effect.</p><p><strong>Keyword</strong>: hydrogen peroxide, wound healing</p>


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