scholarly journals Capacitação Profissional na Geração de Resíduos Sólidos de Serviço de Saúde em Ambiente Hospitalar

UNICIÊNCIAS ◽  
2021 ◽  
Vol 24 (2) ◽  
pp. 146-150
Author(s):  
Huama Monteiro de Brito ◽  
Marcelo Dias de Souza ◽  
Patrícia Paz da Costa ◽  
Géssica Lataliza de Menezes ◽  
Flavia Machado Coelho ◽  
...  
Keyword(s):  
Experimental Study ◽  
Health Services ◽  
Hospital Environment ◽  
Environmental Damage ◽  
Mato Grosso ◽  
Class A ◽  
Qualified Person ◽  
Class D ◽  
Professional Employees ◽  
The Common

O trabalho teve como objetivo analisar a geração de resíduos comuns do Hospital São Luiz de Cáceres do Estado de Mato Grosso, em relação à capacitação dos funcionários no local de trabalho. Trata-se de estudo de intervenção, analítico, experimental de resíduos de serviços de saúde. A realização da capacitação foi no ano de 2017, em que foram abordados cinco pontos de geração no hospital, tendo como prioridade a quantidade de resíduos gerados em cada ponto, sendo quantificados e analisados antes e após a capacitação profissional dos colaboradores. Os resultados demonstraram que os resíduos comuns gerados no local estão sendo descartados de forma incorreta, pois foram observados resíduos da classe A nas lixeiras de classe D, sendo que mesmo com a capacitação, a segregação ainda continuou sendo realizada de forma incorreta por alguns profissionais. Portanto, em função de danos financeiros e ambientais, pode-se dizer que é de suma importância que os profissionais sejam capacitados por uma pessoa qualificada. É necessária uma pessoa capacitada para se responsabilizar pelo PGRSS, SCIH e gestores, aplicando treinamento de capacitação e monitorando diretamente o manejo dos resíduos sólidos gerados no ambiente hospitalar.   Palavras-chave: Lixo Hospitalar. Segregação. Gerenciamento de Resíduos.   Abstract The work aimed to analyze the common residues generation of Hospital São Luiz de Cáceres of the state of Mato Grosso, in relation to the employees training in the workplace. This is an intervention, analytical and experimental study of health services residues. The training was carried out in 2017, in which five generation points were added, having as priority the amount of residues generated in each point, being quantified and advanced and after the professional employees training. The results showed that the common residues generated at the site is being disposed of incorrectly, because class A residues were observed in class D dumps, being that even with the training, the segregation still continued to be performed incorrectly by some professionals. Therefore, due to the financial and environmental damage, it can be said that it is extremely important that professionals are trained by a qualified person. A trained person is required to be responsible for the PGRSS, SCIH and managers, applying training and monitoring directly the solid residues management in the hospital environment.   Keywords: Hospital Garbage. Segregation. Residues Management.

scholarly journals Cyclic Boronates Inhibit All Classes of β-Lactamases

2017 ◽  
Vol 61 (4) ◽  
Author(s):  
Samuel T. Cahill ◽  
Ricky Cain ◽  
David Y. Wang ◽  
Christopher T. Lohans ◽  
David W. Wareham ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Bacterial Infections ◽  
Binding Mode ◽  
Gram Negative ◽  
Content Type ◽  
Class A ◽  
Class D ◽  
Dual Action ◽  
The Common ◽  
Continued Use

ABSTRACT β-Lactamase-mediated resistance is a growing threat to the continued use of β-lactam antibiotics. The use of the β-lactam-based serine-β-lactamase (SBL) inhibitors clavulanic acid, sulbactam, and tazobactam and, more recently, the non-β-lactam inhibitor avibactam has extended the utility of β-lactams against bacterial infections demonstrating resistance via these enzymes. These molecules are, however, ineffective against the metallo-β-lactamases (MBLs), which catalyze their hydrolysis. To date, there are no clinically available metallo-β-lactamase inhibitors. Coproduction of MBLs and SBLs in resistant infections is thus of major clinical concern. The development of “dual-action” inhibitors, targeting both SBLs and MBLs, is of interest, but this is considered difficult to achieve due to the structural and mechanistic differences between the two enzyme classes. We recently reported evidence that cyclic boronates can inhibit both serine- and metallo-β-lactamases. Here we report that cyclic boronates are able to inhibit all four classes of β-lactamase, including the class A extended spectrum β-lactamase CTX-M-15, the class C enzyme AmpC from Pseudomonas aeruginosa, and class D OXA enzymes with carbapenem-hydrolyzing capabilities. We demonstrate that cyclic boronates can potentiate the use of β-lactams against Gram-negative clinical isolates expressing a variety of β-lactamases. Comparison of a crystal structure of a CTX-M-15:cyclic boronate complex with structures of cyclic boronates complexed with other β-lactamases reveals remarkable conservation of the small-molecule binding mode, supporting our proposal that these molecules work by mimicking the common tetrahedral anionic intermediate present in both serine- and metallo-β-lactamase catalysis.

scholarly journals Interactions of Ceftobiprole with β-Lactamases from Molecular Classes A to D

2007 ◽  
Vol 51 (9) ◽  
pp. 3089-3095 ◽  
Author(s):  
Anne Marie Queenan ◽  
Wenchi Shang ◽  
Malgosia Kania ◽  
Malcolm G. P. Page ◽  
Karen Bush
Keyword(s):  
Functional Groups ◽  
Hydrolytic Stability ◽  
Enterobacter Cloacae ◽  
Class A ◽  
Extended Spectrum ◽  
Class D ◽  
The Family ◽  
Class B ◽  
The Common ◽  
Antibacterial Spectrum

ABSTRACT The interactions of ceftobiprole with purified β-lactamases from molecular classes A, B, C, and D were determined and compared with those of benzylpenicillin, cephaloridine, cefepime, and ceftazidime. Enzymes were selected from functional groups 1, 2a, 2b, 2be, 2d, 2e, and 3 to represent β-lactamases from organisms within the antibacterial spectrum of ceftobiprole. Ceftobiprole was refractory to hydrolysis by the common staphylococcal PC1 β-lactamase, the class A TEM-1 β-lactamase, and the class C AmpC β-lactamase but was labile to hydrolysis by class B, class D, and class A extended-spectrum β-lactamases. Cefepime and ceftazidime followed similar patterns. In most cases, the hydrolytic stability of a substrate correlated with the MIC for the producing organism. Ceftobiprole and cefepime generally had lower MICs than ceftazidime for AmpC-producing organisms, particularly AmpC-overexpressing Enterobacter cloacae organisms. However, all three cephalosporins were hydrolyzed very slowly by AmpC cephalosporinases, suggesting that factors other than β-lactamase stability contribute to lower ceftobiprole and cefepime MICs against many members of the family Enterobacteriaceae.

Kinetics of hypso anhydrites dissolution in water. Experimental studies

2019 ◽  
pp. 93-96
Author(s):  
A. L. Lebedev ◽  
I. V. Avilina
Keyword(s):  
Experimental Data ◽  
Experimental Study ◽  
Riccati Equation ◽  
Balance Equation ◽  
Experimental Studies ◽  
Common Ion ◽  
The Common ◽  
Common Ion Effect ◽  
Kinetics Of Dissolution ◽  
Kinetics Of

Experimental study of kinetics of dissolution of hypso anhydrites at 25 ᵒC made it possible to formulate model of the process in the form of a balance equation for the kinetics of dissolution of gypsum, anhydrite (first and second orders, respectively) and kinetics of precipitation of gypsum (second order). The processing of the experimental data were carried out on the basis of the solution of the Riccati equation. When taking into account the common-ion effect on the solubility of gypsum and anhydrite, the calculated values turned out to be more comparable with the experimental ones.

Cooperation Pullout Test of Double Self-Tapping Screws in Wood Structures

2011 ◽  
Vol 374-377 ◽  
pp. 2520-2524 ◽  
Author(s):  
Gang Shi ◽  
Jian Xing Zhang ◽  
Yuan Qing Wang ◽  
Hui Juan Huang ◽  
Zheng Hong Zhang
Keyword(s):  
Experimental Study ◽  
Pullout Test ◽  
The Self ◽  
Connection Strength ◽  
Wood Structure ◽  
Wood Structures ◽  
Pullout Resistance ◽  
Loading Tests ◽  
The Common ◽  
Strength And Stiffness

In this paper, the experimental study on the self-tapping screw’s pullout resistance in the wood structure was conducted. Domestic ordinary screws were used together with imported or domestic wood to fabricate 6 screw connection specimens in wooden walls. Then monotonic loading tests were conducted and it can be concluded that, the common round screw connection strength mainly depends on the failure mode, the lack of cooperation effect significantly influences the strength of screw connections, and the dispersion of screw connection stiffness is high. So, to obtain formulae for the self-tapping screw connection strength and stiffness by further experimental study will be very necessary.

scholarly journals Aspectos clínicos e epidemiológicos relacionados ao transplante de córneas

2019 ◽  
Vol 13 ◽  
Author(s):  
Mayk Penze Cardoso ◽  
Marcos Antonio Ferreira Júnior ◽  
Elenilda De Andrade Pereira Gonçalves ◽  
Vanessa Giavarotti Taboza Flores ◽  
Élen Ferraz Teston ◽  
...  
Keyword(s):  
Health Services ◽  
Corneal Transplantation ◽  
Epidemiological Data ◽  
Distribution Patterns ◽  
Cross Sectional Study ◽  
The State ◽  
Cross Sectional ◽  
Mato Grosso ◽  
Eye Banks ◽  
Mato Grosso Do Sul

RESUMOObjetivo: caracterizar epidemiologicamente os transplantes de córneas realizados no estado de Mato Grosso do Sul. Método: trata-se de estudo quantitativo, epidemiológico, de desenho transversal. Compor-se-á a amostra de estudo de forma censitária por todos os pacientes em fila de espera, os submetidos ao transplante de córneas e os doadores desse tipo de tecido no Estado de Mato Grosso do Sul. Realizar-se-á a coleta de dados por meio de três instrumentos elaborados para cada população distinta, com as variáveis de dados clínicos e epidemiológicos. Estabelecer-se-ão estatisticamente os padrões de distribuição e as frequências, bem como as medidas de tendência central, além da análise multivariada com aplicação de medidas de magnitude de efeito e associação, de acordo com a natureza de cada variável, a serem apresentados em forma de gráficos e tabelas. Resultados esperados: espera-se identificar as dificuldades encontradas no sistema estadual de transplante de córneas com foco no desenvolvimento de conceitos técnicos, de planejamento e organização do atendimento aos usuários em fila de espera, doadores e transplantados. Descritores: Transplante de Córnea; Doenças da Córnea; Retalhos de Tecido Biológico; Epidemiologia; Serviços de Saúde; Bancos de Olhos.ABSTRACTObjective: to make the clinical and epidemiological characterization of corneal transplants performed in the state of Mato Grosso do Sul. Method: this is a quantitative, epidemiological, cross-sectional study. A sample of the study will be collected in a census form for all patients in queue, those submitted to corneal transplantation and donors of this type of tissue in the State of Mato Grosso do Sul. Data collection will be performed by means of three instruments elaborated for each distinct population, with the variables of clinical and epidemiological data. Distribution patterns and frequencies as well as measures of central tendency will be statistically established, as well as multivariate analysis with application of magnitude of effect and association, according to the nature of each variable, to be presented in charts and tables. Expected results: it is hoped to identify the difficulties found in the state transplant system of corneal aimed at the development of technical concepts, planning and organization of care for waiting users, donors and transplanted patients. Keywords: Corneal Transplantation; Corneal Diseases; Biological Tissue Patchwork; Epidemiology; Health services; Eye Banks. Descriptors: Corneal Transplantation; Corneal Diseases; Free Tissue Flaps; Epidemiology; Health Services; Eye Banks.RESUMENObjetivo: caracterizar epidemiológicamente los trasplantes de córneas hechos en el estado de Mato Grosso do Sul. Método: trata-se de un estudio cuantitativo, epidemiológico, de diseño transversal. La muestra de estudio se compondrá de forma censal por todos los pacientes en cola de espera, los sometidos al trasplante de córneas y los donantes de ese tipo de tejido en el Estado de Mato Grosso do Sul. Se realizará la recolección de datos mediante tres instrumentos preparados para cada población distinta, con las variables de datos clínicos y epidemiológicos. Se establecerán estadísticamente los patrones de distribución y las frecuencias, así como las medidas de tendencia central, además del análisis multivariado con aplicación de medidas de magnitud de efecto y asociación, de acuerdo con la naturaleza de cada variable, que deberán presentarse en forma de gráficos y tablas. Resultados esperados: se espera identificar las dificultades encontradas en el sistema estatal de trasplante de córneas mirando el desarrollo de conceptos técnicos, de planificación y organización de la atención a los usuarios en cola de espera, los donantes y los trasplantados. Descriptores: Trasplante de Córnea; Enfermedades de Córnea; Colgajos Tisulares Libres; Epidemiología; Servicios de Salud; Bancos de Ojos.

scholarly journals PEDAGOGICAL CARE IN HOSPITAL ENVIRONMENT

2021 ◽  
Vol 9 (12) ◽  
pp. 16-25
Author(s):  
Laynara Soares Vilagra ◽  
Milene Bartolomei Silva ◽  
Valdir Aragão Nascimento
Keyword(s):  
Children And Adolescents ◽  
Hospital Environment ◽  
Educational Service ◽  
Right To Education ◽  
Mato Grosso ◽  
Sick Children ◽  
The Right ◽  
Teaching Modality ◽  
School Tasks ◽  
Mato Grosso Do Sul

Pedagogical assistance in a hospital environment aims to continue the schooling of children who are hospitalized. In addition, it aims to develop activities that help in training and that help with school tasks during hospitalization. This article aims to publicize the hospital class as an inclusive teaching modality aimed at assisting children and adolescents while they are undergoing health treatment during the period of hospitalization. The bibliographical research presents a scenario about the hospital educational service in Brazil and in the state of Mato Grosso do Sul, showing a growing percentage, however, insufficient of hospital classes to guarantee the right to education of sick children and adolescents.

scholarly journals Genetic Diversity, Biochemical Properties, and Detection Methods of Minor Carbapenemases in Enterobacterales

2021 ◽  
Vol 7 ◽  
Author(s):  
Rémy A. Bonnin ◽  
Agnès B. Jousset ◽  
Cécile Emeraud ◽  
Saoussen Oueslati ◽  
Laurent Dortet ◽  
...  
Keyword(s):  
Genetic Diversity ◽  
Multidrug Resistant ◽  
Biochemical Properties ◽  
Amino Acid Sequences ◽  
Detection Methods ◽  
Gram Negative ◽  
Class A ◽  
Class D ◽  
Class B ◽  
Encoding Genes

Gram-negative bacteria, especially Enterobacterales, have emerged as major players in antimicrobial resistance worldwide. Resistance may affect all major classes of anti-gram-negative agents, becoming multidrug resistant or even pan-drug resistant. Currently, β-lactamase-mediated resistance does not spare even the most powerful β-lactams (carbapenems), whose activity is challenged by carbapenemases. The dissemination of carbapenemases-encoding genes among Enterobacterales is a matter of concern, given the importance of carbapenems to treat nosocomial infections. Based on their amino acid sequences, carbapenemases are grouped into three major classes. Classes A and D use an active-site serine to catalyze hydrolysis, while class B (MBLs) require one or two zinc ions for their activity. The most important and clinically relevant carbapenemases are KPC, IMP/VIM/NDM, and OXA-48. However, several carbapenemases belonging to the different classes are less frequently detected. They correspond to class A (SME-, Nmc-A/IMI-, SFC-, GES-, BIC-like…), to class B (GIM, TMB, LMB…), class C (CMY-10 and ACT-28), and to class D (OXA-372). This review will address the genetic diversity, biochemical properties, and detection methods of minor acquired carbapenemases in Enterobacterales.

Endolymphatic SAC Surgery for Menière's Disease

1983 ◽  
Vol 92 (2) ◽  
pp. 113-118 ◽  
Author(s):  
Gershon J. Spector ◽  
Peter G. Smith
Keyword(s):  
Meniere’S Disease ◽  
Menière’S Disease ◽  
Meniere's Disease ◽  
Ménière’S Disease ◽  
Menière's Disease ◽  
Class A ◽  
Class D ◽  
Class B ◽  
Ménière's Disease

An endolymphatic-mastoid Silastic shunt procedure was performed in 122 cases of Menière's disease having a mean follow-up period of three years. In accordance with American Academy of Ophthalmology and Otolaryngology 1972 criteria, there were 43 % class A, 20% class B, 21% class C, and 17% class D results. Analysis of 35 recent cases having a mean follow-up period of nine months revealed 57% class A, 25% class B, 9% class C, and 9% class D results. Sixteen percent of the patients who experienced classes A, B or C results complained of other fluctuating symptoms which were not relieved by surgery. Moreover, three new eases of otolithic crisis were found in the postoperative group. Seven of ten patients who experienced a class A or B result had either a recrudescence of their vertigo or a significant decrement in hearing in response to a postoperative salt-loading test. It is concluded that the surgical success rate decreases with time and that the procedure appears to alter the symptom complex but does not cure Menière's disease.

Use of Occupational Health Services in a Cyprus Oncology Center

AAOHN Journal ◽  
2009 ◽  
Vol 57 (5) ◽  
pp. 198-201 ◽  
Author(s):  
Helen Provan ◽  
Vasilios Raftopoulos ◽  
Elpidoforos Soteriades
Keyword(s):  
Occupational Health ◽  
Health Services ◽  
Medical Physics ◽  
Hospital Environment ◽  
Health Clinic ◽  
Radiology Department ◽  
Occupational Health Services ◽  
Health Care Planning ◽  
Oncology Center

Use of occupational health services in the hospital environment is an important parameter for annual health care planning. The objective of this study was to evaluate the clinic utilization at a Cyprus oncology center. All visits to the occupational health clinic during an 18-month period were reviewed and analyzed. During the study period, the center had, on average, 161 employees and offered 67 occupational health clinic sessions. Employees had 338 clinic visits, of which 294 were primary and 44 were follow-up visits, with 5 employees, on average, visiting the clinic at each session. Nurses most frequently visited the center (33.4%), followed by the administrative staff (28.6%) and the employees of the Medical Physics and Radiology Department (22.4%), corresponding to the largest groups of employees. The most frequently cited reason for the visits was administrative purposes (23.6%), including updating health records, followed by pre-placement examinations (14.7%) and vaccinations (10.3%). Administrative and clinical reasons were given for occupational health clinic use at the oncology center across all categories of employees.

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