Plantas Medicinais Utilizadas na Região de Diamantina (MG), Cerrado e Campo Rupestre da Serra do Espinhaço (MG)

2018 ◽  
Vol 22 (1) ◽  
pp. 63
Author(s):  
Paloma Caroline de Lima Campos ◽  
Bethânia Alves Avelar-Freitas
Keyword(s):  
Developing Countries ◽  
Medicinal Plants ◽  
Chemical Constituents ◽  
Campo Rupestre ◽  
Pharmacological Properties ◽  
Euphorbia Tirucalli ◽  
Safety And Reliability ◽  
New Research ◽  
The City

O uso de plantas medicinais é praticado na medicina popular, sobretudo, nos países em desenvolvimento. As plantas medicinais são elementos que constituem parte da biodiversidade e são largamente utilizadas desde os primórdios da civilização por vários povos e de diversas maneiras. Estas plantas têm se mostrado de importante relevância como medicamentos caseiros, visto que em suas composições possuem constituintes químicos eficazes para o tratamento de certas doenças. Neste estudo, o objetivo foi realizar uma revisão bibliográfica acerca das plantas medicinais utilizadas no município de Diamantina (MG) e seus entornos, a fim de compilar as informações obtidas para auxiliar nos avanços dos estudos. Utilizando os descritores Plantas medicinais, Diamantina e fitoterápicos foram encontrados 10 artigos, sendo as plantas mais citadas as espécies: Ageratum fastigiatum e Euphorbia tirucalli, as quais apresentaram as atividades sobre células do sistema imune em estudos in vitro. Novas pesquisas e estudos ainda são necessários para comprovação de propriedades farmacológicas e padronização do uso, portanto, ainda há poucas informações sobre a segurança e a confiabilidade das plantas medicinais e novos estudos devem ser apurados acerca do assunto.Palavras-chave: Plantas Medicinais. Vale do Jequitinhonha. Diamantina.AbstractThe use of medicinal plants is practiced by many populations, especially in developing countries. Medicinal plants are elements that constitute part of biodiversity and have been widely used since the dawn of civilization by various peoples and in various ways. They have been shown to be of significant relevance as home remedies, since in their compositions they have effectice chemical constituents for the treatment of certain diseases. In this work the objective was to carry out a bibliographical review about the medicinal plants used in the city of Diamantina (MG) and its surroundings, in order to compile the obtained information to support in the studies advances. Using the descriptors Medicinal plants, Diamantina and phytorerapics, 10 articles were found, the most cited being the species Ageratum fastigiatum and Euphorbia tirucalli, which presented the activities on the cells of the immune system in vitro studies. New research and studies are still necessary to prove pharmacological properties and standardization of the use, therefore, there is still little information about the safety and reliability of medicinal plants and new studies should be determined on the subject.Keywords: Medicinal Plants. Jequitinhonha Valley. Diamantina.

scholarly journals A Review of the Ethnomedicinal Uses, Biological Activities, and Triterpenoids of Euphorbia Species

Molecules ◽  
2020 ◽  
Vol 25 (17) ◽  
pp. 4019
Author(s):  
Douglas Kemboi ◽  
Xolani Peter ◽  
Moses Langat ◽  
Jacqueline Tembu
Keyword(s):  
Drug Discovery ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Structural Diversity ◽  
Pharmacological Properties ◽  
Anticancer Activities ◽  
Sensory Disorders ◽  
Wide Range ◽  
Ethnomedicinal Uses

The genus Euphorbia is one of the largest genera in the spurge family, with diversity in range, distribution, and morphology. The plant species in this genus are widely used in traditional medicine for the treatment of diseases, ranging from respirational infections, body and skin irritations, digestion complaints, inflammatory infections, body pain, microbial illness, snake or scorpion bites, pregnancy, as well as sensory disorders. Their successes have been attributed to the presence of diverse phytochemicals like polycyclic and macrocyclic diterpenes with various pharmacological properties. As a result, Euphorbia diterpenes are of interest to chemists and biochemists with regard to drug discovery from natural products due to their diverse therapeutic applications as well as their great structural diversity. Other chemical constituents such as triterpenoids have also been reported to possess various pharmacological properties, thus supporting the traditional uses of the Euphorbia species. These triterpenoids can provide potential leads that can be developed into pharmaceutical compounds for a wide range of medicinal applications. However, there are scattered scientific reports about the anticancer activities of these constituents. Harnessing such information could provide a database of bioactive pharmacopeia or targeted scaffolds for drug discovery. Therefore, this review presents an updated and comprehensive summary of the ethnomedicinal uses, phytochemistry, and the anticancer activities of the triterpenoids of Euphorbia species. Most of the reported triterpenoids in this review belong to tirucallane, cycloartanes, lupane, oleanane, ursane, and taraxane subclass. Their anticancer activities varied distinctly with the majority of them exhibiting significant cytotoxic and anticancer activities in vitro. It is, therefore, envisaged that the report on Euphorbia triterpenoids with interesting anticancer activities will form a database of potential leads or scaffolds that could be advanced into the clinical trials with regard to drug discovery.

A Review of Traditional Uses, Phytochemistry, and Pharmacological Properties of the Genus Saururus

2020 ◽  
Vol 48 (01) ◽  
pp. 47-76 ◽  
Author(s):  
Guangxin Liu ◽  
Zefeng Zhao ◽  
Meilun Shen ◽  
Xue Zhao ◽  
Jing Xie ◽  
...  
Keyword(s):  
Chemical Constituents ◽  
Control Measures ◽  
Lipid Lowering ◽  
Pharmacological Properties ◽  
Clinical Value ◽  
In Vivo Models ◽  
Traditional Uses ◽  
Tract Infections

The genus Saururus, belonging to Saururaceae, contains two species, S. cernuus L. and S. chinensis (Lour) Baill. with common utilization in traditional medicine from Asia to North America for the treatment of edema, beriberi, jaundice, leucorrhea, urinary tract infections, hypertension, hepatitis diseases, and tumors. An extensive review of literature was made on traditional uses, phytochemistry, and ethnopharmacology of Saururus using ethno-botanical books, published articles, and electronic databases. The 147 of chemical constituents have been isolated and identified from S. cernuus and S. chinensis, and lignans, flavonoids, alkaloids, anthraquinones, saponins, and phenols are the major constituents. Various pharmacological investigations in many in vitro and in vivo models have revealed the potential of the genus Saururus with anti-inflammatory, antitumor, anti-oxidant, hepatoprotective, antimelanogenic, lipid-lowering, and bone protective activities, supporting the rationale behind numerous of its traditional uses. Due to the noteworthy pharmacological properties, Saururus can be a better option for new drug discovery. Data regarding many aspects of this plant such as toxicology, pharmacokinetics, quality-control measures, and the clinical value of the active compounds is still limited which call for additional studies.

QUANTITATIVE PHYTOCHEMICAL DETERMINATIONS AND IN-VITRO CYTOTOXIC ACTIVITY OF MEDICINAL PLANTS

2015 ◽  
Vol 1 (01) ◽  
pp. 17-21
Author(s):  
P. Ethalsha Robert ◽  
A. Malar Retna
Keyword(s):  
Medicinal Plants ◽  
Cytotoxic Activity ◽  
Chemical Constituents ◽  
Chloroform Extract ◽  
Total Phenol ◽  
Total Phenol Content ◽  
Medicinal Uses ◽  
Anti Cancer ◽  
Cancer Activity

The present study evaluates in-vitro cytotoxic activity of active extracts of medicinal plants. It evaluates anti-cancer activity of most active extracts of I. pes-caprae and C. roseus. This study focuses on the total phenol content and the total flavanoid content of the plant and searches into its medicinal potency based on the total phenol and total flavanoid content. The anti-cancer activity of the extract is found to be more significant than one another.The cytotoxic activity of Ipomoea pes-caprae and C. roseus showed better results. Methanol extracts of aerial and root of Ipomoea pes-caprae possess maximum anticancer activity is found to be 61.77% and 65.55%. Chloroform extract of Catharanthus roseus root was also active against MCF- 7 cells by exhibiting 64.34% of activity. These plants may be a source of new antibiotic compounds.These findings enriches our knowledge of the chemical constituents that are responsible for the medicinal uses of the plant and the anti-cancer potential of selected plants.

Geographical variation in Chemo profile, Genetic profile and In-vitro Anticancer activity of Chitraka (Plumbago zeylanica Linn.) collected from Himalayas and Western Ghats

2019 ◽  
Vol 4 (04) ◽  
Author(s):  
Rajesh Sharma ◽  
Shraddha Naik ◽  
Vikas Saroch
Keyword(s):  
Medicinal Plants ◽  
Anticancer Activity ◽  
Western Ghats ◽  
Chemical Constituents ◽  
Himalayan Region ◽  
Chemical Components ◽  
Genetic Profile ◽  
Anticancer Activities ◽  
Plumbago Zeylanica

Therapeutic actions of medicinal plants are due to the chemical components present in them. These chemical constituents often vary with change in geographical and climatic conditions. Climate, altitude, and temperature play an important role to make a herb therapeutically potent. Ancient Ayurvedic physicians mentioned that medicinal plants which grow in Himalayan region are more potent as compared to the plants growing in other regions. A modest study was therefore undertaken to compare the in vitro anticancer activity of Plumbago zeylanica Linn. collected from Himalayan region and Western Ghats with respect to their chemo profile and genetic patterns. Variation in physio-chemical, phyto-chemical, the genetic profiles were observed in plants collected from these two regions and corresponding variation was also seen in their anticancer activities.

Ferulic Acid and Cardiovascular Health: Therapeutic and Preventive Potential

2021 ◽  
Vol 21 ◽  
Author(s):  
Evandro Manoel Neto-Neves ◽  
Carlos da Silva Maia Bezerra Filho ◽  
Naiara Naiana Dejani ◽  
Damião Pergentino de Sousa
Keyword(s):  
Cardiovascular Diseases ◽  
Animal Models ◽  
Medicinal Plants ◽  
Ferulic Acid ◽  
Cardiovascular Health ◽  
Mechanisms Of Action ◽  
Pharmacological Properties ◽  
In Vitro Experiments ◽  
Beneficial Effects

: Bioactive compounds found in food and medicinal plants contribute to maintaining health and treating illnesses. For example, hydroxycinnamic acids, such as ferulic acid, are widely present in nature and have several pharmacological properties, including antioxidant, anti-inflammatory, and beneficial effects in parameters of diabetes and hyperlipidemia. In fact, the results of studies in animal models and in vitro experiments of ferulic acid suggest its high therapeutic and preventive potential against several pathological disorders, such as cardiovascular diseases. Therefore, in this review, the bioactivities of ferulic acid on the cardiovascular system are described, including the discussion of the mechanisms of action in the various components of the system. In this review, we discuss the pharmacological properties of this versatile natural product in aspects of cardiovascular health, including cardioprotective and antihypertensive actions, and on the metabolism of lipids, diabetes, and thrombosis.

scholarly journals Genus Stachys: A Review of Traditional Uses, Phytochemistry and Bioactivity

Medicines ◽  
2020 ◽  
Vol 7 (10) ◽  
pp. 63
Author(s):  
Ekaterina-Michaela Tomou ◽  
Christina Barda ◽  
Helen Skaltsa
Keyword(s):  
Biological Activities ◽  
Chemical Constituents ◽  
Present Review ◽  
Pharmacological Properties ◽  
Pharmacological Activities ◽  
Traditional Medicines ◽  
Traditional Uses ◽  
Perennial Herbs ◽  
New Research ◽  
Phytochemical Profiles

Background: The genus Stachys L. (Lamiaceae) includes about 300 species as annual or perennial herbs or small shrubs, spread in temperate regions of Mediterranean, Asia, America and southern Africa. Several species of this genus are extensively used in various traditional medicines. They are consumed as herbal preparations for the treatment of stress, skin inflammations, gastrointestinal disorders, asthma and genital tumors. Previous studies have investigated the chemical constituents and the biological activities of these species. Thus, the present review compiles literature data on ethnomedicine, phytochemistry, pharmacological activities, clinical studies and the toxicity of genus Stachys. Methods: Comprehensive research of previously published literature was performed for studies on the traditional uses, bioactive compounds and pharmacological properties of the genus Stachys, using databases with different key search words. Results: This survey documented 60 Stachys species and 10 subspecies for their phytochemical profiles, including 254 chemical compounds and reported 19 species and 4 subspecies for their pharmacological properties. Furthermore, 25 species and 6 subspecies were found for their traditional uses. Conclusions: The present review highlights that Stachys spp. consist an important source of bioactive phytochemicals and exemplifies the uncharted territory of this genus for new research studies.

scholarly journals Exploring essential oils as prospective therapy against the ravaging Coronavirus (SARS-CoV-2)

2020 ◽  
Vol 2 (4) ◽  
pp. 322-330
Author(s):  
Emmanuel Onah Ojah ◽  
Keyword(s):  
Medicinal Plants ◽  
Essential Oils ◽  
Viral Infections ◽  
Chemical Constituents ◽  
Antiviral Agents ◽  
Biological Properties ◽  
Drug Candidate ◽  
Anti Cancer

Introduction: Aromatic plants produce diverse chemical constituents with potential to inhibit viral infections. These plants have been utilized for the prevention and treatment of a range of infectious and non-infectious diseases. Essential oils are among the plant-derived antiviral agents that are being employed in phytomedicine, and are considered as prospective drug candidate against the ravaging Coronavirus. Methods: Relevant articles relating to the concept were identified using a combination of manual library search as well as journal publication on the subject and critically reviewed. Results: Essential oils in medicinal plants have extensive applications in medicinal chemistry, aromatherapy and pharmaceuticals. Essential oils have several biological properties such as antibacterial, antifungal, antiviral, antioxidant, anti-inflammatory, wound-healing and anti-cancer effects in vitro and in vivo. Several reports have analyzed and described essential oils as good antiviral agents against Respiratory tract viral infections hence are excellent prospective candidate against Corona virus. Conclusions: It is hoped that efficient and effective exploration and optimization of essential oils from medicinal plants would improve the drug discovery process against the ravaging Coronavirus.

scholarly journals Pharmacological, medicinal and toxicological properties of lavender essential oil: A review

2021 ◽  
Vol 10 (5) ◽  
pp. e23310514933
Author(s):  
Gabriel Fernando Esteves Cardia ◽  
Francielli Maria de Souza Silva-Comar ◽  
Edvalkia Magna Teobaldo da Rocha ◽  
Saulo Euclides Silva-Filho ◽  
Mayara Zagotto ◽  
...  
Keyword(s):  
Natural Products ◽  
Medicinal Plants ◽  
Essential Oil ◽  
Adverse Effects ◽  
Essential Oils ◽  
Traditional Medicine ◽  
New Drugs ◽  
Pharmacological Properties ◽  
New Research ◽  
Therapeutic Possibilities

The natural products extracted from plants are part of traditional medicine and are also therapeutic possibilities for treating many diseases. Recently, its use in the development of new drugs has shown much visibility for its efficiency and few adverse effects. Essential oils extracted from medicinal plants are indicated to treat numerous diseases due to their antimicrobial, antiviral, antimutagenic, anticancer, antioxidant, anti-inflammatory, immunomodulatory, and antiprotozoal properties. Among essential oils, lavender essential oil stands out for having several important pharmacological properties. This review detailed the main studies on essential oils from different species of lavender and obtained a valuable collection on all their pharmacological, medicinal and toxicological potential. In this context, we evaluated lavender essential oil as a promising substance that can help treat several diseases. We provide some evidence and an overview of the potential therapeutic effect of lavender essential oil to guide new research.

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