Medication Errors in Compounding Pharmacy

AbstractThe traditional role of compounding pharmacies is to make drugs prescribed by physicians for patients with needs that cannot be met by commercially available drugs. Medication errors have attracted attention of health authorities since they compromise the patient’s assistance, enhance morbidity rates and increase the healthcare costs. This study analyzed medication errors that occurred in a compounding pharmacy school in order to identify types and periodicity and to outline strategies in the service delivery process to mitigate such errors. This is a retrospective descriptive study carried out from March to June of 2018 and based on the analysis of occurrences recorded by the service sector of a magistral pharmacy school in Rio de Janeiro. The errors were classified according to the stage in the pharmaceutical assistance process and reached 124 records, with an average of 1.03 occurrence/day. The main causes were prescription errors (95 occurrences or 76.60%), administering (12 occurrences or 9.68%), labeling (7 occurrences or 5.65%), dispensing (7 occurrences or 5.65%) and handling (3 occurrences or 2.42%). The errors in the prescription stage, the most frequent ones, were potential but intercepted and cleared before they resulted in a harmful outcome. This study identified medication errors in a magistral pharmacy. The errors were potential but intercepted and resolved before they resulted in a harmful outcome. The results points to the need for systematic surveillance of adverse events in a more active way and for standardizing the procedures throughout the process, from assessing the medical prescription to guiding the patient for proper administration and storage. Keywords: Pharmaceutical Preparations. Risk Management. Pharmacovigilance. Pharmacoepidemiology. ResumoO papel tradicional das farmácias de manipulação é manipular medicamentos prescritos por médicos para pacientes com necessidades que não podem ser atendidas pelos medicamentos disponíveis no mercado. Os erros de medicação são eventos que vêm recebendo grande destaque entre autoridades sanitárias por contribuírem com o aumento das taxas de morbidade e dos custos do sistema de saúde, comprometendo a qualidade da assistência prestada ao paciente. O presente estudo teve por objetivo analisar os principais erros de medicação observados em uma Farmácia Escola magistral localizada no sudeste do Brasil. Foi desenvolvido um estudo descritivo retrospectivo no período de março a junho de 2018, baseado na análise das ocorrências de erros de medicação registradas no período. Os erros foram classificados de acordo com as etapas da assistência farmacêutica. Um total de 124 registros foram verificados no período, com média diária de 1,03 ocorrências/dia. As principais causas destes registros foram em 95 (76,60%) devido a erros de prescrição, 3 (2,42%) referentes à erros de manipulação dos medicamentos, 7 (5,65%) erros de rotulagem, 7 (5,65%) erros de dispensação, e 12 (9,68%) referentes à erros de administração do medicamento pelo paciente. Os erros de maior frequência foram relacionados à escrituração da prescrição. Os erros verificados eram potenciais e foram interceptados e resolvidos antes que resultassem em um desfecho danoso. Os resultados indicaram a necessidade de avançar para uma vigilância sistemática de eventos adversos de forma mais ativa e padronização das condutas relacionadas aos processos desde a avaliação da qualidade da prescrição até a orientação para administração e guarda adequada do medicamento pelo paciente. Palavras-chave: Preparações Farmacêuticas. Gestão de Riscos. Farmacovigilância. Farmacoepidemiologia.

Download Full-text

Renewed energy in Asia's upstream

The APPEA Journal ◽

10.1071/aj18193 ◽

2019 ◽

Vol 59 (2) ◽

pp. 582

Author(s):

Gero Farruggio ◽

David Dixon

Keyword(s):

Solar Wind ◽

Service Sector ◽

Oil And Gas ◽

Oil Companies ◽

National Oil Companies ◽

Grid Connection ◽

New Energy ◽

Operational Expenditure ◽

And Storage

Upstream is enjoying a renewed optimism in pricing and project developments, and the growth outlook is positive. That said, current investment in upstream across Asia is less than half that of renewable projects, which accounted for over US $180 billion in 2018. Got your attention? It certainly has for national oil companies and regional oil and gas players as companies explore the opportunities presented by lowering solar and storage costs. In this paper we analyse capex trends and forecasts across both sectors in Australia and the region. Will this growth continue, who is set to gain and by how much? We explore the growing role of renewables in the oilfield service sector. Australia is not alone in experiencing a renewables boom; the trend continues across Asia, with government initiatives more often than not being the catalyst and the boom then fuelled by a seemingly endless supply of insatiable investors. Australia is experiencing a frenzy of activity; developers are rushing to grab land and be the first past the post on grid connection. What can we expect as the renewable energy target transitions to the national energy guarantee, to whatever comes next? We compare the corporate landscapes across the upstream and new energy sectors, and explore what is driving them closer each year as miners and upstream operators turn to solar, wind and storage to reduce operational expenditure and boost field economics. Adani has one of the largest solar pipelines in Australia; will Woodside follow suit? Finally, we compare returns for recently commissioned renewable and upstream projects.

Download Full-text

THE ROLE OF ANTHROPONYMS IN THE SEMANTIC FIELD OF ARTISTIC WORKS

Naukovy Visnyk of South Ukrainian National Pedagogical University named after K D Ushynsky Linguistic Sciences ◽

10.24195/2616-5317-2019-29-6 ◽

2019 ◽

Vol 2019 (29) ◽

pp. 66-77

Author(s):

Lidiya Derbenyova

Keyword(s):

Literary Work ◽

Main Theme ◽

Semantic Field ◽

New Meanings ◽

Minor Part ◽

The One ◽

A Minor ◽

And Storage ◽

Horizon Of Expectations

The article explores the role of antropoetonyms in the reader’s “horizon of expectation” formation. As a kind of “text in the text”, antropoetonyms are concentrating a large amount of information on a minor part of the text, reflecting the main theme of the work. As a “text” this class of poetonyms performs a number of functions: transmission and storage of information, generation of new meanings, the function of “cultural memory”, which explains the readers’ “horizon of expectations”. In analyzing the context of the literary work we should consider the function of antropoetonyms in vertical context (the link between artistic and other texts, and the groundwork system of culture), as well as in the context of the horizontal one (times’ connection realized in the communication chain from the word to the text; the author’s intention). In this aspect, the role of antropoetonyms in the structure of the literary text is extremely significant because antropoetonyms convey an associative nature, generating a complex mechanism of allusions. It’s an open fact that they always transmit information about the preceding text and suggest a double decoding. On the one hand, the recipient decodes this information, on the other – accepts this as a sort of hidden, “secret” sense.

Download Full-text

FAITHâ€“BASED COMMUNITIES AND POLITICS IN DULLSTROOM-EMNOTWENI: LOCAL STORIES OF IDENTITY

Oral History Journal of South Africa ◽

10.25159/2309-5792/1594 ◽

2016 ◽

Vol 1 (1) ◽

pp. 45-57 ◽

Cited By ~ 2

Author(s):

Christina Landman

Keyword(s):

Higher Education ◽

Service Delivery ◽

Special Focus ◽

Traditional Role ◽

Cultural Conflicts ◽

Local Identities ◽

Political Interests ◽

Local Municipality ◽

The Face

A majority of the black community of Dullstroom-Emnotweni in the Mpumalanga highveld in the east of South Africa trace their descent back to the southern Ndebele of the so-called â€˜Mapoch Grondenâ€™, who lost their land in the 1880s to become farm workers on their own land. A hundred years later, in 1980, descendants of the â€˜Mapoggersâ€™ settled in the newly built â€˜townshipâ€™ of Dullstroom, called Sakhelwe, finding jobs on the railways or as domestic workers. Oral interviews with the inhabitants of Sakhelwe â€“ a name eventually abandoned in favour of Dullstroom- Emnotweni â€“ testify to histories of transition from landowner to farmworker to unskilled labourer. The stories also highlight cultural conflicts between people of Ndebele, Pedi and Swazi descent and the influence of decades of subordination on local identities. Research projects conducted in this and the wider area of the eMakhazeni Local Municipality reveal the struggle to maintain religious, gender and youth identities in the face of competing political interests. Service delivery, higher education, space for women and the role of faith-based organisations in particular seem to be sites of contestation. Churches and their role in development and transformation, where they compete with political parties and state institutions, are the special focus of this study. They attempt to remain free from party politics, but are nevertheless co-opted into contra-culturing the lack of service delivery, poor standards of higher education and inadequate space for women, which are outside their traditional role of sustaining an oppressed community.

Download Full-text

The Service Sector in the Economy in Poland and European Union Countries

Olsztyn Economic Journal ◽

10.31648/oej.3146 ◽

2015 ◽

Vol 10 (3) ◽

pp. 191-207

Author(s):

Walentyna Kwiatkowska

Keyword(s):

Service Sector ◽

Value Added ◽

Total Employment ◽

Eu Countries ◽

Gross Value Added ◽

European Union Countries ◽

Service Sectors ◽

Sector Theory ◽

The Eu

The role of the service sector in the economy is increasing in the process of socio-economic development. This tendency has been confirmed and explained by the three-sector theory formulated by A.G.B. Fisher, C. Clark, and J. Fourastie. The main goal of the paper is to show development tendencies in service sectors in Poland and the EU countries and assess them in view of the three-sector theory. The share of the service sector in the total employment and in the total gross value added in the years 2005-2013/2014 will be analysed together with two sub-sectors including market and non-market services. The research shows that the share of the service sector in total employment and total gross value added has been recently increasing in Poland as well as in other EU countries, but there is a gap in this process between Poland and the most developed EU countries. Moreover, in Poland, the role of market services has been recently increasing much faster than the role of non-market services.

Download Full-text

The role of lipid metabolism and signalling during postharvest treatment and storage of horticultural crops

Stewart Postharvest Review ◽

10.2212/spr.2008.3.7 ◽

2008 ◽

Vol 4 (3) ◽

pp. 1-8

Author(s):

Fernando Alferez

Keyword(s):

Lipid Metabolism ◽

Horticultural Crops ◽

Postharvest Treatment ◽

And Storage

Download Full-text

Effects and Side Effects of Platelet Transfusion

Hämostaseologie ◽

10.1055/a-1347-6551 ◽

2021 ◽

Author(s):

Fabrice Cognasse ◽

Kathryn Hally ◽

Sebastien Fauteux-Daniel ◽

Marie-Ange Eyraud ◽

Charles-Antoine Arthaud ◽

...

Keyword(s):

Side Effects ◽

Immune Responses ◽

Platelet Transfusion ◽

Biological Response ◽

Innate Immune ◽

Innate Immune Responses ◽

Stress Injury ◽

Processing And Storage ◽

And Storage

AbstractAside from their canonical role in hemostasis, it is increasingly recognized that platelets have inflammatory functions and can regulate both adaptive and innate immune responses. The main topic this review aims to cover is the proinflammatory effects and side effects of platelet transfusion. Platelets prepared for transfusion are subject to stress injury upon collection, preparation, and storage. With these types of stress, they undergo morphologic, metabolic, and functional modulations which are likely to induce platelet activation and the release of biological response modifiers (BRMs). As a consequence, platelet concentrates (PCs) accumulate BRMs during processing and storage, and these BRMs are ultimately transfused alongside platelets. It has been shown that BRMs present in PCs can induce immune responses and posttransfusion reactions in the transfusion recipient. Several recent reports within the transfusion literature have investigated the concept of platelets as immune cells. Nevertheless, current and future investigations will face the challenge of encompassing the immunological role of platelets in the scope of transfusion.

Download Full-text

Applications of Energy Beams in Material and Device Processing

MRS Proceedings ◽

10.1557/proc-23-25 ◽

1983 ◽

Vol 23 ◽

Author(s):

G.J. Galvin ◽

L.S. Hung ◽

J.W. Mayer ◽

M. Nastasi

Keyword(s):

Ion Beam ◽

High Energy ◽

Ion Beams ◽

Traditional Role ◽

Near Surface ◽

Device Processing ◽

Composition Modification ◽

Directed Energy ◽

Transistor Fabrication

ABSTRACTEnergetic ion beams used outside the traditional role of ion implantation are considered for semiconductor applications involving interface modification for self-aligned silicide contacts, composition modification for formation of buried oxide layers in Si on insulator structures and reduced disorder in high energy ion beam annealing for buried collectors in transistor fabrication. In metals, aside from their use in modification of the composition of near surface regions, energetic ion beams are being investigated for structural modification in crystalline to amorphous transitions. Pulsed beams of photons and electrons are used as directed energy sources in rapid solidification. Here, we consider the role of temperature gradients and impurities in epitaxial growth of silicon.

Download Full-text

Effects of Employee Sickness Presence on Customer Repurchase and Recommendation Intentions: The Role of Customer Affective Reactions

Journal of Business and Psychology ◽

10.1007/s10869-021-09764-1 ◽

2021 ◽

Author(s):

Carolin Dietz ◽

Hannes Zacher

Keyword(s):

Service Sector ◽

Productivity Loss ◽

Phone Call ◽

Negative Effects ◽

Disease Avoidance ◽

Positive Effects ◽

Sickness Presence ◽

Organizational Consequences ◽

Health Deterioration

AbstractSickness presence can have important individual and organizational consequences, such as health deterioration or productivity loss. Additional risks, such as negative customer reactions, may be particularly relevant in the service sector. Based on affective events theory and appraisal theories, we hypothesize that employee sickness presence negatively impacts customer repurchase and recommendation intentions. Furthermore, we explore potential affective mechanisms of these effects, including disease avoidance, personal anger, moral outrage, post-consumption guilt, and customer compassion for the employee. We conducted four studies, including three experimental vignette methodology studies (Ns = 227, 72, and 763) and a qualitative study (N = 54). In Study 1, employee sickness presence had negative effects on repurchase and recommendation intentions. Results of Study 2 show that customers experienced disgust, fear, anger, guilt, compassion, and indifference in response to sickness presence. In Study 3, anger explained the negative effects of employee sickness presence on repurchase and recommendation intentions, while appraisals of moral fairness were negatively related to both customer intentions. Finally, in Study 4, disgust and anger explained negative effects, while fear, guilt, and compassion explained positive effects of employee sickness presence on customer intentions. Appraisals of goal incongruence, reduced agency of the customer, and uncertainty were negatively related to customer intentions. The physical absence of the customer in the service encounter (phone call) mitigated the experience of disgust, fear, and anger, whereas it exacerbated feelings of compassion for the ill employee.

Download Full-text

Preparedness and response in Portuguese emergency plans - Interaction with public health

European Journal of Public Health ◽

10.1093/eurpub/ckaa165.868 ◽

2020 ◽

Vol 30 (Supplement_5) ◽

Author(s):

G Leiras ◽

A Martins

Keyword(s):

Public Health ◽

Health Authority ◽

Civil Protection ◽

Emergency Plans ◽

Emergency Situations ◽

Health Measures ◽

Health Authorities ◽

Public Health Authorities ◽

Protection Authority

Abstract Background Articulation between Civil Protection and Public Health authorities is of paramount importance to control, reduce and prevent threats to the health of the population in situations of crisis or catastrophes. National Civil Protection Authority produces Emergency Plans which describe the role of every stakeholder in emergency situations. Role and importance of Public Health and Public Health Authorities is not always present or well described and known amongst stakeholders. Methods Data was collected from all Districtal Emergency Plans (n = 18). Each document was analysed considering time frame, refences to Public Health and Health Authorities, definition of roles, communication channels, coordination and inclusion of intersectoral communication flow. Quantitative analysis included absolute and relative frequencies and qualitative analysis to all parts related to the terms “Public Health” and “Health Authority”. Each document was reviewed by 2 independent researchers. Results From 18 Districtal Emergency Plans (DEP) analysed, 94,4% (n = 17) had references to Public Health, but none referred the role of Public Health Officers. Only 16,7% referred to Health Authorities, although 94,4% mentioned the law 135/2013, defining the role and attributes of Health Authority. In 72,2%, coordination of Public Health Measures was attributed to the National Medical Emergency Institute. Epidemiological surveillance and Public Health Emergencies were referred in 55,6%, and attributed to the Regional Administration of Health. Conclusions Public Health Authorities and Public Health Medical Officers role in articulation with National Civil Protection Authority in emergency situations lacks severely, with this role being replaced by other entities. This is of great concern regarding management and control of diseases, particularly communicable diseases. Key messages Public Health Authorities lack the necessary involvement in Emergency Plans and emergency situations. Public health measures are coordinated by other entities rather than Public Health Authorities.

Download Full-text