scholarly journals Comprehensive geriatric assessment in elderly and senile patients with cardiovascular diseases. Expert opinion of the Russian Association of Gerontologists and Geriatricians

Kardiologiia ◽  
2021 ◽  
Vol 61 (5) ◽  
pp. 71-78
Author(s):  
O. N. Tkacheva ◽  
Yu. V. Kotovskaya ◽  
N. K. Runihina ◽  
E. V. Frolova ◽  
A. S. Milto ◽  
...  
Keyword(s):  
Cardiovascular Diseases ◽  
Elderly Patients ◽  
Scientific Information ◽  
Geriatric Syndrome ◽  
Multiple Systems ◽  
Loss Of Self ◽  
Self Sufficiency ◽  
Physiological Reserve ◽  
Exogenous Factors ◽  
And Function

Senile asthenia syndrome (SAS) is a geriatric syndrome characterized by age-associated decline of the physiological reserve and function in multiple systems, which results in higher vulnerability to effects of endo- and exogenous factors and a high risk of unfavorable outcomes, loss of self-sufficiency, and death. Generally, SAS is observed in elderly patients with comorbidities. In cardiovascular diseases, SAS is associated with a poor prognosis, including a higher incidence of exacerbation and death both during acute events and in chronic disease. However, SAS is often not taken into account in developing diagnostic and therapeutic programs for managing elderly patients with cardiovascular diseases (CVD). This article analyzes available scientific information about SAS, algorithms for SAS diagnosis, and the scales that may be useful in developing individual plans for management of elderly patients with CVD.

Surgery for Lung Cancer and the Consequences for the Swallow

2016 ◽  
Vol 1 (13) ◽  
pp. 162-168
Author(s):  
Pippa Hales ◽  
Corinne Mossey-Gaston
Keyword(s):  
Lung Cancer ◽  
Treatment Options ◽  
Vocal Cord Palsy ◽  
Subsequent Treatment ◽  
Physiological Reserve ◽  
Palliative Phase ◽  
And Function ◽  
The Impact ◽  
Swallow Function

Lung cancer is one of the most commonly diagnosed cancers across Northern America and Europe. Treatment options offered are dependent on the type of cancer, the location of the tumor, the staging, and the overall health of the person. When surgery for lung cancer is offered, difficulty swallowing is a potential complication that can have several influencing factors. Surgical interaction with the recurrent laryngeal nerve (RLN) can lead to unilateral vocal cord palsy, altering swallow function and safety. Understanding whether the RLN has been preserved, damaged, or sacrificed is integral to understanding the effect on the swallow and the subsequent treatment options available. There is also the risk of post-surgical reduction of physiological reserve, which can reduce the strength and function of the swallow in addition to any surgery specific complications. As lung cancer has a limited prognosis, the clinician must also factor in the palliative phase, as this can further increase the burden of an already compromised swallow. By understanding the surgery and the implications this may have for the swallow, there is the potential to reduce the impact of post-surgical complications and so improve quality of life (QOL) for people with lung cancer.

Food for Thought on Pediatric Feeding and Swallowing

2008 ◽  
Vol 17 (3) ◽  
pp. 110-118 ◽  
Author(s):  
Joan C. Arvedson
Keyword(s):  
Developmentally Appropriate ◽  
Evidence Based ◽  
Silent Aspiration ◽  
Multiple Systems ◽  
Young Infants ◽  
Adequate Understanding ◽  
Nutrition And Hydration ◽  
Pediatric Feeding ◽  
Areas Of Concern ◽  
And Function

Abstract “Food for Thought” provides an opportunity for review of pertinent topics to add to updates in areas of concern for professionals involved with feeding and swallowing issues in infants and children. Given the frequency with which speech-language pathologists (SLPs) make decisions to alter feedings when young infants demonstrate silent aspiration on videofluoroscopic swallow studies (VFSS), the need for increased understanding about cough and its development/maturation is a high priority. In addition, understanding of the role(s) of laryngeal chemoreflexes (LCRs), relationships (or lack of relationships) between cough and esophagitis, gastroesophageal reflux (GER), and chronic salivary aspiration is critical. Decision making regarding management must take into account multiple systems and their interactions in order to provide safe feeding for all children to meet nutrition and hydration needs without being at risk for pulmonary problems. The responsibility is huge and should encourage all to search the literature so that clinical practice is as evidence-based as possible; this often requires adequate understanding of developmentally appropriate neurophysiology and function.

On the clinical significance of HDL cholesterol at the present stage

2021 ◽  
Vol 19 (1) ◽  
pp. 50-53
Author(s):  
V. N. Oslopov ◽  
◽  
Yu. V. Oslopova ◽  
E. V. Khazova ◽  
E. R. Girfanutdinova ◽  
...  
Keyword(s):  
Cardiovascular Diseases ◽  
Blood Plasma ◽  
Clinical Studies ◽  
Hdl Cholesterol ◽  
Epidemiological Studies ◽  
Present Stage ◽  
The World ◽  
Cast Doubt ◽  
And Function ◽  
Role And Function

The leading death cause in the world is diseases of the cardiovascular system, with CHD as the leader in the structure of cardiovascular diseases. The cause of this disease is atherosclerosis. One of the possible causes of atherosclerosis is an increase in LDL-C and a decrease in HDL-C in the blood. Many epidemiological studies have reliably shown that HDL cholesterol reduces the risk of developing cardiovascular diseases. Data from recent studies cast doubt on this data. The review briefly describes the current understanding of the effect of HDL-C high levels on morbidity and mortality, lists the new approaches to assessing the role and function of these particles, presents the results of clinical studies of drugs that affect their concentration in blood plasma and the probable causes leading to an increase of the HDL-Cin content in the blood.

scholarly journals Aging clinical problems: a difficult balance between age and frailty

2016 ◽  
Vol 84 (1-2) ◽  
Author(s):  
Renzo Rozzini
Keyword(s):  
Public Health ◽  
Older Adults ◽  
Weight Loss ◽  
Elevated Risk ◽  
Geriatric Syndrome ◽  
Central Focus ◽  
Health Practitioners ◽  
And Function ◽  
Public Health Practitioners ◽  
Clinical Problems

<p>Frailty is a common geriatric syndrome that embodies an elevated risk of catastrophic declines in health and function among older adults. Frailty is a condition associated with ageing with associated weakness, slowing, decreased energy, lower activity, and, when severe, unintended weight loss. As a population ages, a central focus of geriatricians and public health practitioners is to understand, and then beneficially intervene on, the factors and processes that put elders at such risk, especially the increased vulnerability to stressors (e.g. extremes of heat and cold, infection, injury, or even changes in medication) that characterizes many older adults. The syndrome of geriatric frailty is hypothesized to reflect impairments in the regulation of multiple physiologic systems, embodying a lack of resilience to physiologic challenges and thus elevated risk for a range of deleterious endpoints. The empirical assessment of geriatric frailty in individuals seeks to capture this or related features.</p><p><strong>Riassunto</strong></p><p>Fragilità è la predisposizione alla rottura, al danno. L’etimologia della parola fragilità da "frango", rompere, rimanda alla nozione di qualche cosa che se sottoposto a una pressione, a un impatto, rischia di danneggiarsi facilmente. E’ dunque una nozione ampia e intuitiva che può avere ambiti di precisazione più diversi a seconda che se ne parli in fisica (dove esistono dei coefficienti esatti) piuttosto che nei campi della morale o del sentimento, dove la valutazione sarà sempre più "poetica" e affidata alla sensibilità individuale.</p>

Pharmacology and Drug Therapy in Critically Ill Elderly Patients

1992 ◽  
Vol 3 (1) ◽  
pp. 137-148 ◽  
Author(s):  
Mary K. Walker
Keyword(s):  
Older Adults ◽  
Critical Care ◽  
Drug Therapy ◽  
Drug Metabolism ◽  
Elderly Patients ◽  
Treatment Modality ◽  
Drug Disposition ◽  
Structure And Function ◽  
Living Things ◽  
And Function

Aging is a complex, normal, and inevitable process affecting all living things. The physiologic changes of aging, by definition, are postmaturational, occurring after adult maturity is achieved. Changes with aging are primary, irreversible, and progressive. While the processes of aging are neither pathology nor disease, they present important changes in structure and function that alter drug disposition, metabolic rate, and excretion. These changes present special challenges to clinicians in critical care settings for whom pharmacotherapy is a common treatment modality. This article explores the physiologic changes associated with aging and the implications of these changes for management of critically compromised elders. Drug metabolism, distribution, utilization, and excretion in older adults are examined

Sign in / Sign up

Export Citation Format

Share Document