Foot Arch and Plantar Pressure in the Age of 17-21 Years

Research on the plantar segment has not been widely carried out in Indonesia’s population, even though the plantar segment data will be essential in further research and therapy of plantar-related problems. Therefore, this research intends to describe the plantar profile: the foot arch and the plantar pressure difference between the right and left foot. This research applied a cross-sectional study. Subjects were recruited from the Faculty of Medicine students, Universitas Indonesia, class 2012, with inclusion criteria aged 17-21 years and normal gait. Meanwhile, the exclusion criteria consisted of having postural abnormalities, a history of neuromusculoskeletal disorders in the lower limbs, a history of fractures in the spine and legs, a history of surgery on the spine and legs, and refusing to participate in the study. Research subjects stood on a plantar scanner, conducted at the Anatomy Laboratory, the Faculty of Medicine, Universitas Indonesia. The Mann-Whitney test was then used to analyze the difference in plantar pressure between the right and left foot. The results revealed that a hundred research subjects had a proportion of a low foot arch of 4%, a normal foot arch of 89%, and a high foot arch of 7%. The median right plantar pressure was 273.5 KPa, while the median left plantar pressure was 253.5 KPa. The Mann-Whitney test showed a p-value of 0.954 for the pressure difference between right and left foot. There was no plantar pressure difference between the right and left foot.

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EFEKTIVITAS POSISI TANGAN PENOLONG DALAM PENCEGAHAN RUPTUR PERINEUM PADA PERSALINAN NORMAL

Jurnal Kebidanan ◽

10.35872/jurkeb.v9i01.309 ◽

2017 ◽

Vol 9 (01) ◽

pp. 68

Author(s):

Mulyati Priyantini ◽

Yuli Trisnawati

Keyword(s):

Maternal Morbidity ◽

P Value ◽

Cross Sectional ◽

Second Stage Of Labor ◽

Whitney Test ◽

Second Stage ◽

Mann Whitney Test ◽

Significant Difference ◽

U Value ◽

Quota Sampling

ABSTRAKFokus utama asuhan persalinan adalah pencegahan komplikasi untuk mengurangi angka kesakitan dan kematian ibu. Salah satu upaya adalah mencegah terjadinya ruptur perineum. Posisi tangan yang dipakai penolong persalinan kala II untuk mencegah ruptur perineum antara lain posisi tangan APN dan Varney. Penelitian ini bertujuan untuk mengetahui efektivitas antara posisi tangan penolong menurut APN dan menurut Varney dalam mencegah ruptur perineum spontan pada kala II persalinan di RSIA ‘Bunda arif’ Purwokerto. Penelitian ini merupakan penelitian observasional analitik, menggunakan pendekatan cross sectional dengan populasi seluruh persalinan spontan di RSIA ‘Bunda arif’ Purwokerto. Sampel yang digunakan adalah quota sampling sebanyak 30 sampel yang memenuhi kriteria inklusi. Metode analisis data menggunakan uji U Mann-Whitney. Hasil penelitian ini adalah Kejadian ruptur perineum pada posisi tangan menurut APN sebanyak 93,3%, sedangkan menurut Varney sebanyak 86,7%. Hasil analisa statistik uji U Mann-Whitney didapatkan p value = 0,550 (p>0,005) sedangkan U value = 33,000 (Uh < U t ), artinya tidak ada perbedaan bermakna, tetapi posisi tangan Varney lebih baik dengan selisih ruptur 6,6%. Posisi tangan penolong menurut Varney lebih efektif daripada posisi tangan menurut APN dalam pencegahan ruptur perineum spontan pada kala II persalinan, tetapi keduanya tidak memberikan perbedaan yang bermakna terhadap kejadian ruptur perineum. Penolong persalinan dapat menemukan metode yang paling tepat dalam meminimalisir kejadian ruptur perineum spontan untuk menurunkan angka kesakitan dan kematian ibu.Keyword : Posisi tangan penolong, ruptur perineumEFFECTIVENESS OF HANDLING POSITION IN PREVENTION OF PERINEUM RUPTURE IN NORMAL LABORABSTRACTMain focus of delivery care is preventing the complication to reduce the maternal morbidity and mortality. One of the efforts to prevent the occurance of perineal rupture. The position hand which is used birth attendant in the second stage of labor to prevent perineal rupture among others APN and Varney hands position. The goal of this reasearch is to know the effectiveness between APN and Varney hands position to prevent spontanoeus perineal rupture in the second stage of labor in RSIA ‘Bunda arif’ Purwokerto. This reasearch was observational analytic by approachment cross sectional with population of this reasearch was all of spontaneous delivery in RSIA ‘Bunda arif’ Purwokerto and the sample used quota sampling, it’s about 30 sample can be a inclusion criteria. The analyze method data used U Mann-Whitney test. The result of this experiment are precentage of spontaneous perineal rupture by APN hands position is 93,3%, while by Varney is 86,7%. Result of statistic analysis used U Mann-Whitney test is p value = 0,550 (p>0.005) and U value = 33,000 (Uh < U t). It means, not significant difference, but Varney hands position better by a margin of 6.6%. the conclusion are varney hands position is more effective than APN hands position in prevention spontaneous perineal rupture in the second stage of labor, but both not significant for perinel rupture. Suggestion : Birth attendants can find the most appopriate method to minimize perineal ruptured to reduce maternal morbidity and mortalityKeyword : APN & Varney hands position, and perineal rupture.

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La acción de juego en desigualdad numérica por periodos en waterpolo (The game action of the power play in water polo by periods)

Retos ◽

10.47197/retos.v0i27.34337 ◽

2015 ◽

pp. 14-18

Author(s):

Pablo García-Marín ◽

Francisco Manuel Argudo Iturriaga ◽

José Ignacio Alonso Roque

Keyword(s):

Longitudinal Design ◽

Match Analysis ◽

Whitney Test ◽

Water Polo ◽

Mann Whitney Test ◽

Play Game ◽

The Right ◽

Power Play

El objetivo de este estudio fue conocer la influencia de los periodos de juego en la dinámica de la acción de juego en desigualdad numérica temporal simple con posesión en waterpolo. Para ello se utilizó un diseño nomotético, multidimensional y de seguimiento. Se analizaron 1230 desigualdades en 95 partidos del Campeonato del Mundo de Waterpolo de Barcelona 2003. Se utilizó la prueba de Kruskal-Wallis para discriminar las categorías con diferencias entre periodos. Posteriormente la prueba U de Mann-Whitney permitió localizar qué periodos de los cuatro diferían entre sí. En la categoría masculina se encontraron diferencias significativas (p < .05) en: lanzamiento frente tenso, posición de lanzamiento izquierda delante, posición de lanzamiento derecha delante, y exclusión sin posesión. Las diferencias alcanzadas en el campeonato femenino fueron: posición de lanzamiento desde el palo derecho, pase previo al lanzamiento desde izquierda detrás, pase previo al lanzamiento desde el palo derecho, duración, parada e introducción del móvil en la portería por el lateral derecho. Se concluye que existe poca variación de la dinámica de la acción de juego en desigualdad entre periodos. El análisis del adversario previo y durante el partido puede ayudar a reducir la incertidumbre de los jugadores y aumentar el rendimiento del equipo.Palabras clave. waterpolo, desigualdad, periodo de juego, masculino, femenino.Abstract. The aim of this study was to determine the influence of game periods on dynamics of the game action during power play in water polo. A nomothetic, multidimensional and longitudinal design was used. Power play situations (n = 1230) were analyzed in 95 matches from World Water Polo Championships in Barcelona 2003. To discriminate the categories with differences by periods the Kruskal-Wallis test was used. Then the specific differences among periods were found with U Mann-Whitney test. Significant statistical differences (p < .05) were found in men championship: drive shot, origin of shot from left forward, origin of shot from right forward, and exclusion fouls without possession. Differences found in women championships were: origin of shot from right pole, last pass before throwing from left backward, last pass before throwing from right pole, duration, detention and goals on the right side. It was concluded that there were little changes on dynamics of the game in power play between periods. The previous and live match analysis of the opponent team could reduce the incertitude of players and increase team performance.Keywords. water polo, power play, game period, male, female.

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Tabletop Tsunami Simulator In Tsunami Disaster Preparation To Make Schools Of Disaster Preparedness

Jurnal Kesehatan dr. Soebandi ◽

10.36858/jkds.v9i1.267 ◽

2021 ◽

Vol 9 (1) ◽

pp. 55-59

Author(s):

Feri Ekaprasetia ◽

Guruh Wirasakti

Keyword(s):

Primary School ◽

Vulnerable Groups ◽

P Value ◽

Attitude Score ◽

Whitney Test ◽

Tsunami Disaster ◽

Knowledge And Attitudes ◽

Mann Whitney Test ◽

Post Test ◽

The Impact

Introduction: Tsunami in Indonesia become a threat to society, especially for vulnerable groups. Primary school students are one of the vulnerable groups that should have adequate preparedness both in their knowledge and attitudes in facing the tsunami. To support the preparedness, a tabletop tsunami simulator has been developed. Objective: To describe the tsunami preparedness of school-age children and to assess the impact of the tabletop tsunami simulator on the knowledge and attitudes of school children towards tsunamis. Methods: The study design was a one group pre-test – post-test design with a total participant of 157 students. The research instrument used was a tabletop tsunami simulator and a questionnaire to assess knowledge and attitude towards tsunamis. The statistical test used was the Mann Whitney test. The inclusion criteria included primary school 5th and 6th grade students, had a smartphone, and were willing to be participants. The data was collected using Google form and had obtained ethical approval number 62/SDS/KEPK/TL/VI/2020. Result: The Mann Whitney test showed a significant effect between the tabletop tsunami simulator and the participants’ knowledge of tsunamis with a p-value of 0.000 (p-value <0.05). In the attitude variable, an increase in the attitude score between the pre-test and post-test was also observed. The average attitude score increased from 32.99 to 34.97, with a p-value = 0.000. Conclusion: There is a significant effect between the tabletop tsunami simulator with the participants’ knowledge and attitudes in facing the threat of a tsunami.

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Hemichorea-hemiballismus in a patient with hyperglycaemic hyperosmolar state

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20204257 ◽

2020 ◽

Vol 8 (10) ◽

pp. 3710

Author(s):

Rifkatu S. Reng ◽

Odumodu Kenechukwu ◽

Shuaibu Ramatu ◽

Oyakhire Shyngle ◽

Omonua Special ◽

...

Keyword(s):

Basal Ganglia ◽

Involuntary Movement ◽

Rare Complication ◽

Cerebral Atrophy ◽

Lower Limbs ◽

High Grade Fever ◽

Rare Manifestation ◽

History Of ◽

Hypertensive Woman ◽

The Right

Hemichorea-hemiballismus (HCHB) is a rare manifestation of hyperglycaemic hyperosmolar state caused by contralateral lesion in basal ganglia. A 74-year-old, known diabetic and hypertensive woman presented with one-week history of high-grade fever and loss of consciousness associated with involuntary movement of the right upper and lower limbs for 10 hours prior to presentation. Physical examination revealed pyrexia, tachycardia and altered sensorium. Blood glucose was 53.8 mmol/l, hemoglobin A1c (Hb A1c) 9.9% and brain computed tomography (CT) scan showed cerebral atrophy with bilateral basal ganglia hyperdensities. Escherichia coli was cultured from the urine. She did well on treatment with soluble insulin, rehydration and intravenous ceftriaxone. HCHB is a rare complication seen in patients with poorly controlled diabetes mellitus. This report highlights the reversibility of the disease with prompt diagnosis and appropriate insulin treatment. HCHB should be distinguished from other intracranial pathologies.

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Efektifitas endorphin massage terhadap fungsi seksual perempuan pada masa menopause

Jurnal Kebidanan dan Keperawatan Aisyiyah ◽

10.31101/jkk.315 ◽

2018 ◽

Vol 13 (1) ◽

pp. 88-94

Author(s):

Sri Wahyuni ◽

Tutik Rahayu

Keyword(s):

Data Processing ◽

Sexual Function ◽

Wilcoxon Test ◽

P Value ◽

Female Sexual Function ◽

Z Score ◽

Whitney Test ◽

Mann Whitney Test ◽

Before And After

Abstract: The purpose of this study is to identify the effectiveness ofendorphine massage on female sexual function during menopause inNgampel District of Kendal Regency. Sampling was done by samplingcriteria acsidental aged less than 60 years old, have a husband, in a healthycondition. Data processing was performed using the Wilcoxon test todetermine differences in sexual function before and after the interventionwhile endorphine effectiveness of massage performed by using MannWhitney.Hasil research: Wilcoxon test showed that there are significantdifferences in sexual function before and after being given endorphineMassage with p value 0.00. While Mann Whitney test showed p value of0.13 and the value of z score of -2.828, which means there is a stronginfluence among endorphine Massage to increased sexual function soendorphine Massage is effective for improving sexual function.

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ONSET PENGELUARAN KOLOSTRUM PERSALINAN NORMAL LEBIH CEPAT DARIPADA PERSALINAN SECTIO CAESARIA

Media Ilmu Kesehatan ◽

10.30989/mik.v5i3.164 ◽

2019 ◽

Vol 5 (3) ◽

pp. 193-199

Author(s):

Maria NSW Kause ◽

Yanita Trisetiyaningsih ◽

Anastasia Suci Sukmawati

Keyword(s):

Breast Milk ◽

Post Partum ◽

Sampling Technique ◽

P Value ◽

Cross Sectional ◽

Whitney Test ◽

Mann Whitney Test ◽

The Difference ◽

Cross Sectional Design ◽

First Time

Background: Lactation onset is a term of multiplying breast milk until the release of breast milk for the first time. It is also perceived by mothers as a bit hard breast, inflammed, and full of breast milk or the release of colostrum. Colostrum is the first liquid secreted by breast milk gland since the first day until the fourth day of labour. One of the factors that influences lactation onset is labour methods. Mothers who undergo sectio caesaria surgery will experience pain and prolonged effects of anesthesia compared to mothers with normal labors. Objective: To investigate the difference of colostrum releasing onset in post partum mothers with normal labors and sectio caesaria in Panembahan Senopati General Hospital, Bantul. Method: This study was quantitative with cross sectional design. The number of samples were 80 respondents selected with purposive sampling technique. Study instrument was observational sheets. Data analysis applied Mann-Whitney test. Result: The majority of respondents who had normal labors and sectio caesaria experienced different colostrum onset. In normal labors, the time of colostrum release was 1 day. In sectio caesaria labors, the time of colostrum release was 2 days. The average duration of post partum mothers with normal labors was 13,6 hours and post partum mothers with sectio caesaria was 22,6 hours. The result of Mann-Whitney test was that there was a difference between colostrum release onset of post partum mothers with normal labors and sectio caesaria with p-value of 0,001 (p<0,05). Conclusion: Colostrum onsets were different in normal labors and sectio caesaria labors. Keyword: Colostrum, Normal labors, Sectio Caesaria labors.

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Pengaruh Range Of Motion Untuk Menurunkan Nyeri Sendi Pada lansia Dengan Osteoartritis di Wilayah Puskesmas Godean I Sleman Yogyakarta

Care Jurnal Ilmiah Ilmu Kesehatan ◽

10.33366/cr.v6i1.785 ◽

2018 ◽

Vol 6 (1) ◽

pp. 36

Author(s):

Maruli Taufandas ◽

Elsye Maria Rosa ◽

Moh Afandi

Keyword(s):

Range Of Motion ◽

Wilcoxon Test ◽

Control Group ◽

P Value ◽

Control Group Design ◽

Whitney Test ◽

Group Design ◽

Mann Whitney Test

Salah satu penyakit degeneratif pada lansia yang sering dialami yaitu osteoartritis, yang ditandai dengan adanya nyeri pada ekstremitas bawah dan prevalensinya semakin meningkat dengan bertambahnya usia. Penatalaksanaan non farmakologi merupakan komponen yang sangat penting dalam mengatasi nyeri, salah satu bentuknya adalah latihan Range of Motion. Tujuan: Penelitian ini bertujuan untuk mengetahui pengaruh Range of Motion untuk menurunkan nyeri sendi pada lansia dengan osteoartritis di wilayah kerja Puskesmas Godean I Sleman Yogyakarta. Metode :Penelitian ini adalah study intervensi berupa penelitian kuantitatifdengan rancangan Quasi Eksperiment Design: Pretest-Posttest Control Group Design. Penelitian dilakukan di dua dusun di Kabupaten Sleman yaitu di dusun Mertosutan dan dusun Ngabangan.Sampel pada penelitian ini sebanyak 36 orang lansia dengan masing-masing 18 lansia sebagai kelompok intervensi dan 18 lansia sebagai kelompok kontrol.Pengambilan sampel menggunakan teknik purposive sampling.Analisis data yang digunakan adalah Wilcoxon Test dan Mann Whitney Test. Hasil : Setelah melakukan latihan Range of Motionselama 4 minggu, didapatkan hasil bahwa terdapat pengaruh Range of Motion terhadap skala nyeri sendi pada lansia dengan osteoartritis dengan p value 0,000 (α < 0,05). Kesimpulan :Range of Motion berpengaruh secara signifikan terhadap penurunan tingkat skala nyeri sendi pada lansia dengan osteoartritis

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Adaptive Nonparametric Tests for the Generalized Behrens-Fisher Problem

Austrian Journal of Statistics ◽

10.17713/ajs.v39i4.252 ◽

2016 ◽

Vol 39 (4) ◽

Author(s):

Uttam Bandyopadhyay ◽

Atanu Biswas ◽

Dhiman Dutta

Keyword(s):

Probabilistic Approach ◽

Nonparametric Tests ◽

P Value ◽

Test Procedures ◽

Whitney Test ◽

Test For Symmetry ◽

Mann Whitney Test ◽

Nominal Size ◽

Median Test ◽

The One

Some adaptive test procedures are developed for the generalized Behrens-Fisher problem. The one having a deterministic approach is based on calculating a measure of symmetry from each sample and using them as a basis for choosing between the modifiedWilcoxon-Mann-Whitney test (Fligner and Policello, 1981) and the modified Mood’s median test (Fligner and Rust, 1982). The other one is a probabilistic approach which also uses a combination of the modified Wilcoxon-Mann-Whitney test and the modified Mood’smedian test according to an evidence of asymmetry provided by the p-value from the triples test for symmetry given in Randles, Fligner, Policello, and Wolfe (1980). This probabilistic approach is further modified by using a suitable function of the p-value from the triples test. A simulation study reveals that the modified procedure performs reasonably well in terms of power and attainment of the nominal size.

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Pengaruh Diabetes Self Management Education (DSME) terhadap Self Management pada Pasien Diabetes Mellitus

Jurnal Ilmiah Kesehatan ◽

10.48144/jiks.v12i2.174 ◽

2019 ◽

Vol 12 (2) ◽

Author(s):

Trina Kurniawati ◽

Titih Huriah ◽

Yanuar Primanda

Keyword(s):

Diabetes Mellitus ◽

Management Education ◽

Intervention Group ◽

Simple Random Sampling ◽

Wilcoxon Test ◽

Self Management ◽

Control Group ◽

P Value ◽

Whitney Test ◽

Mann Whitney Test

AbstrakEdukasi kepada pasien Diabetes Mellitus (DM) yang dapat memperbaiki hasil klinis adalah Diabetes Self Management Education (DSME). DSME merupakan salah satu metode yang dapat memfasilitasi pengetahuan dan keterampilan. Penelitian ini bertujuan untuk mengetahui pengaruh Diabetes Self Management Education terhadap Self Management pada pasien DM. Penelitian ini menggunakan metode penelitian quasi experimental dengan control group pre test- post test design. Teknik pengambilan sampel menggunakan teknik Simple random sampling dengan jumlah sampel sebanyak 46 orang yang terbagi menjadi 23 orang pada kelompok intervensi mendapatkan DSME sebanyak 4 sesi dalam satu bulan dan 23 orang pada kelompok kontrol mendapatkan edukasi dari Program PERSADIA. Instrumen yang digunakan menggunakan kuesioner. Analisis statistik menggunakan Wilcoxon dan Mann Whitney test. Hasil penelitian menunjukkan bahwa P value uji Wilcoxon test sebesar 0,000 pada kelompok intervensi, P value uji Mann Whitney test adalah 0,000 pada variabel self management. Berdasarkan hasil uji statistik didapatkan p<0,05 yang menunjukkan bahwa terdapat perbedaan nilai self management antara kelompok intervensi dengan kelompok kontrol secara signifikan. Kesimpulan penelitian ini adalah DSME dapat meningkatkan self management pada pasien DM. Disarankan petugas kesehatan dapat memberikan DSME untuk meningkatkan self management pasien diabetes dan menggunakan DSME sebagai program promosi kesehatan.Kata kunci: Diabetes Mellitus; DSME;Self Management The Influnce of Diabetes Self Management Education (DSME) to the Self Management on the Diabetes Patient AbstractEducation to patients Diabetes Mellitus (DM) who can improve clinical outcomes is Diabetes Self Management Education (DSME). DSME is one method that can facilitate knowledge and skills. The purpose of this research is to determine the effect of Diabetes Self Management Education (DSME) to Self Management on the diabetes patients. This study is used the quasi experimental research method with control group pre test post test design. The sampling technique used Simple random sampling with a samples of 46 people and it is devided 23 people in the intervention group get DSME as much as 4 sessions in one month and 23 people in the control group get education programe at PERSADIA. The instrument used was questionnaire. Statistical analysis used Wilcoxon and Mann Whitney test. The results showed that P value of Wilcoxon test was 0.000 in the intervention group, P test value of Mann Whitney test was 0.000 in self management variable. Based on statistical test results obtained p <0.05 which indicates that there are differences in self-management value between the intervention group and the control group significantly. The conclusions of this research is DSME can improve self-management on the patients with diabetes. It is recommended that health workers can provide DSME to improve self-management in diabetic patients and use DSME as a health promotion program.Keywords : Diabetes Mellitus, DSME, Self Management

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Διερεύνηση του ρόλου των κατασταλτικών αυτοαντισωμάτων έναντι του υποδοχέα της θυρεοτρόπου ορμόνης ως αίτιου αποβολών στις εγκύους με θυρεοειδική αυτοανοσία

10.12681/eadd/42287 ◽

2013 ◽

Author(s):

Κωνσταντίνος Τουλής

Keyword(s):

P Value ◽

Exact Test ◽

Whitney Test ◽

Fisher's Exact Test ◽

Mann Whitney Test ◽

Fisher’S Exact Test

Σκοπός Με βάση περιπτώσεις μοριακού μιμητισμού μεταξύ των γλυκοπρωτεϊνών και των υποδοχέων τους, διατυπώσαμε την υπόθεση ότι αυτοαντισώματα έναντι του υποδοχέα της θυρεοτροπίνης (TSH-Rab) κατασταλτικού τύπου (blocking) πιθανά να έχουν δραστικότητα αποκλειστή επί του υποδοχέα της ανθρώπινης χοριακής γοναδοτροπίνης (LH/hCG-R) στο ωχρό σωμάτιο, το τελικό βιολογικό αποτέλεσμα της οποίας θα ήταν η απώλεια κύησης κατά το πρώτο τρίμηνο. Ο σκοπός της μελέτης ήταν η κλινική διερεύνηση της παραπάνω υπόθεσης και συγκεκριμένα η διερεύνηση της παρουσίας και εκτίμηση των συγκεντρώσεων bTSH-Rab στις γυναίκες με θυρεοειδίτιδα Hashimoto και ιστορικό καθ’ έξιν αποβολών (ασθενείς) και η σύγκριση τους με γυναίκες με θυρεοειδίτιδα Hashimoto και φυσιολογικό αναπαραγωγικό ιστορικό (μάρτυρες). Ασθενείς και Μέθοδοι Συνολικά επιλέχθηκαν 86 γυναίκες (46 ασθενείς και 46 μάρτυρες με ηλικιακή εξομοίωση) από εξωτερικά ιατρεία και κλινικές του Νομού Θεσσαλονίκης στο πλαίσιο αναδρομικής μελέτης τύπου ασθενών-μαρτύρων. Για τη συμπερίληψη στην ομάδα των ασθενών, η γυναίκα έπρεπε να είχε ηλικία μικρότερη των 35 ετών στην τελευταία αποβολή και κάτω των 50 ετών κατά την επιλογή, χωρίς να εντοπίζονταν από το ιστορικό, την κλινική εξέταση και τον κατά περίπτωση παρακλινικό έλεγχο, δευτεροπαθείς αιτίες καθ’ έξιν αποβολών. Σε υπο-ομάδα των ασθενών (n=15) πραγματοποιήθηκε ορμονολογική εκτίμηση υποφυσιακής λειτουργίας, διακολπικό υπερηχογράφημα πυέλου, καρυότυπο, ανίχνευση μεταλλάξεων του παράγοντα V, μέτρηση επιπέδων ομοκυστεΐνης, αυτοαντισωμάτων έναντι της διπλής έλικας του DNA, αντιπηκτικού του λύκου, β2-γλυκοπρωτείνης και αντικαρδιολιπινικών αντισωμάτων. Η στατιστική ανάλυση πραγματοποιήθηκε με το λογισμικό Stata 10.0 Αποτελέσματα Δεν ανιχνεύθηκε σημαντική διαφορά στον επιπολασμό (Fisher’s exact test, p-value = 1.00) ή στους τίτλους TSH-Rab μεταξύ των ασθενών και των μαρτύρων (Mann-Whitney test, p = 0.59). Οι αναλύσεις ευαισθησίας με βάση τους ορισμούς των καθ’ έξιν αποβολών, των αυτόματων αποβολών, της θυρεοειδίτιδας Hashimoto και της θετικότητας των TSH-Rab δεν τροποποίησαν την κατεύθυνση των ευρημάτων. Η απουσία συσχέτισης μεταξύ TSH-Rab και αναπαραγωγικού ιστορικού επιβεβαιώθηκε σε μονομεταβλητό μοντέλο λογαριθμικής παλινδρόμησης [OR = 1.00, 95% CI = 0.19-5.25], είτε όταν χρησιμοποιήθηκε ο τίτλος των TSH-Rab (OR = 0.77, 95% CI = 0.29 - 2.08). Η παρουσία των TSH-Rab δεν προέβλεψε με στατιστικώς σημαντικό τρόπο τον αριθμό των αυτόματων αποβολών στις ασθενείς (Coef = -0.4, 95% CI = -1.15 - 0.34, p = 0.285) και απουσία συσχέτισης επιβεβαιώθηκε όταν χρησιμοποιήθηκε ο τίτλος τους (Coef = -.0.53, 95% CI = -1.08 - 0.10, p = 0.054). Τα παραπάνω ευρήματα παρέμειναν ανθεκτικά στην ιεραρχική στάθμιση με την ηλικία και το ΒΜΙ κατά την τελευταία κύηση ή αποβολή σε πολυμεταβλητά μοντέλα παλινδρόμησης. Συμπεράσματα Στην παρούσα μελέτη, δεν προέκυψαν ενδείξεις ότι τα TSH-Rab έχουν σημαντικό ρόλο στην παθογένεια των αυτόματων αποβολών και δεν μπορεί να υποστηριχθεί η κλινική και ερευνητική χρησιμότητα της ανίχνευσής τους στις γυναίκες με θυρεοειδίτιδα Hashimoto και ιστορικό καθ’ έξιν αποβολών.

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