scholarly journals Prevalence of hypoglycemia in diarrheal dehydration at hospitalization in severe acute malnutrition

2018 ◽  
Vol 5 (3) ◽  
pp. 1092 ◽  
Author(s):  
Rameshwar Ninama ◽  
Chakshu Chaudhry ◽  
Rameshwar Lal Suman ◽  
Suresh Goyal ◽  
Ramprakash Prakash Bairwa ◽  
...  

Background: Diarrhea is the major cause of death in children below five years of age. Hypoglycemia has been a potential fatal complication of infectious diarrhea in both well-nourished and poorly nourished children. But prevalence of hypoglycemia in diarrheal dehydration is not exactly known. This study was done to evaluate the glycemic status in children having acute diarrhea with dehydration and specifically associated with severe acute malnutrition (SAM).Methods: This descriptive cross-sectional study was conducted during July 2017 to December 2017 at Bal Chikitsalaya Udaipur, Rajasthan, India. Blood glucose levels were assessed in 150 children of acute diarrhea with dehydration, comprising of 100 SAM and 50 Non SAM children.Results: Average blood glucose of SAM children was 89 mg/dl and of non-SAM, it was 120 mg/dl. Average blood glucose was low in SAM as compared to non-SAM in both some dehydration (116.08±21.26) and severe dehydration (66.69±19.80) as well as with or without ORS intake. Overall 18 (12%) of children had hypoglycemia and all were in severe dehydration and not taking ORS. Blood glucose levels were statistically low in severe dehydration and those who were not taking ORS at the time of hospitalization (p = 0.001). In severe dehydration 25% of children had hypoglycemia means every fourth child had low blood glucose <54 mg/dl.Conclusions: Overall prevalence of hypoglycemia is 12% in diarrheal dehydration and 20% in SAM with dehydration. Twenty five percent of severe dehydration children had hypoglycemia, and all have not started ORS. None of the child started ORS developed hypoglycaemia.

2021 ◽  
Vol 17 (4) ◽  
pp. 157
Author(s):  
Ni Ketut Sutiari ◽  
Ali Khomsan ◽  
Hadi Riyadi ◽  
Faisal Anwar ◽  
Desak Putu Yuli Kurniati ◽  
...  

Health status and micronutrient intake among vegetarian and non-vegetarian in BaliBackground: Several studies have reported that vegetarian diets have health benefits for those adopting the diets.Objective: This study aimed to compare anemia status and micronutrient intake between vegetarians and non-vegetarians in Bali.Methods: This cross-sectional study was conducted in Bali. A total of 240 samples consisting of 160 vegetarians and 80 non-vegetarians were randomly selected. Hemoglobin (Hb) and fasting blood sugar levels were measured using the cyanmethemoglobin method and enzymatic colorimetric, respectively. Meanwhile, the data on micronutrient intakes were collected by interviews using the semi-quantitative food frequency questionnaire (SQFFQ). The data were analyzed using descriptive statistics, and the Mann-Whitney test was performed to analyze the differences.Results: The study’s results showed that the mean Hb levels in the vegetarian group were significantly lower than non-vegetarians (p=0.002; p<0.05), and the anemia status in vegetarian women were higher (22.5%) than non-vegetarian women (2.5%). The mean fasting blood glucose level in non-vegetarians was significantly higher than in the vegetarian group (p=0.000; p<0.05). There were no differences in zinc (Zn) intake between vegetarians and non-vegetarians, but there were significant differences (p<0.05) in vitamin C, vitamin D, vitamin B12, folic acid, magnesium (Mg), calcium (Ca), and iron (Fe) intakes.Conclusions: There were differences in anemia status and fasting blood glucose levels between vegetarians and non-vegetarians. The fasting blood glucose levels of non-vegetarians were higher than vegetarians, and there were differences in the intake of certain micronutrients between vegetarians and non-vegetarians.


Nutrients ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 4141
Author(s):  
Helena J. Bentil ◽  
Alyssa M. Abreu ◽  
Seth Adu-Afarwuah ◽  
Joseph S. Rossi ◽  
Alison Tovar ◽  
...  

Low magnesium intake has been shown to be associated with an increased risk of type 2 diabetes mellitus (T2DM) in several studies conducted in high-income countries. However, very few studies have been performed in Africa, where many countries have a growing rate of T2DM. We conducted a pilot cross-sectional study among 63 women in Ghana to investigate the association between magnesium intake and glycemic markers. We assessed dietary magnesium using a food frequency questionnaire and glycemic markers using fasting blood glucose and glycated hemoglobin A1c (HbA1c). Our findings showed that the mean magnesium intake was 200 ± 116 mg/day. The prevalence of T2DM was 5% by measuring fasting blood glucose and 8% by measuring HbA1c. Unadjusted linear regression models revealed that higher magnesium intake significantly predicted higher fasting blood glucose levels (β = 0.31; 95% CI: 0.07, 0.55; p = 0.01) and HbA1c levels (β = 0.26; 95% CI: 0.01, 0.51; p = 0.04). In adjusted analyses, magnesium intake was no longer significantly associated with either fasting blood glucose levels (β = 0.22; 95% CI: −0.03, 0.46; p = 0.08) or HbA1c levels (β = 0.15; 95% CI: −0.08, 0.39; p = 0.20). In conclusion, our study did not show a significant association between magnesium intake and glycemic markers in women of reproductive age in Ghana. The results of this study need to be further substantiated because this was the first study to examine magnesium intake and glycemic markers in this population in Africa.


Author(s):  
Meiriani . ◽  
Yuneldi Anwar ◽  
Puji Pinta Omas Sinurat

Background: Diabetes and higher HbA1c level have increased the incidence of stroke. Hemoglobin levels both high and low are associated with poor outcomes. Leukocytes play an important role in the initiation of the atherosclerosis process.Methods: This was a cross-sectional study with a sample size of 62 people selected by non-random sampling method on a consecutive basis, patients with acute stroke were taken blood to measure blood glucose levels, HbA1c, Hb and Leucocytes when entering the hospital room. Outcomes were assessed using NIHSS and MRS. The calculation of NIHSS and MRS scores was performed on the first day of admission and the fourteenth day. To analyze the correlation of blood sugar levels during HbA1c, Hb and leukocytes in acute stroke, this study used Spearman's correlation test. The p value <0.05 was considered statistically significant.Results: The study subjects of 62 acute stroke patients (acute ischemic stroke 31 people and 31 people hemorrhagic stroke). Acute stroke patients were consisted of 38 men (61.3%) and 24 women (38.7%). Of 31 people with hemorrhagic stroke, there were 16 men (51.6%) and 15 women (48.4%), ischemic stroke patients were consisted of 22 people (71, 0%) and women were 9 people. Spearrman repair test showed no symptoms between blood glucose levels, HbA1c, Hemoglobin and leukocytes with outcomes in acute stroke.Conclusions: There was no significant association between blood glucose levels, HbA1c, hemoglobin and leukocytes with outcomes in acute stroke.


2021 ◽  
Vol 7 (1) ◽  
pp. 27
Author(s):  
Muhammad Ryznar Faisal Nur Luqmani ◽  
Kristianningrum Dian Sofiana ◽  
Bagus Hermansyah

Increase in blood glucose levels can be caused by the long-term use of pesticides by farmers. This study aims to determine whether there is a correlation between the activity of cholinesterase as an indicator of exposure to pesticides and blood glucose of farmers in Mlokorejo Village, Jember Regency. The research method is observational-analytic with a cross-sectional study design. Data in the form of general characteristics of the sample were obtained through interviews, while the data of the activity of cholinesterase and blood glucose levels of farmers were obtained at the Biochemical Laboratory of the Faculty of Medicine, Jember University. The sample size of this study is 30 samples. All of the samples are having an increased activity of cholinesterase. Most of the samples are having normal blood glucose levels. Based on the results of statistical analysis using the Spearman correlation test (a= 0.05), it was concluded that there was no significant correlation between the two variables (p = 0,191). Keywords: blood glucose, cholinesterase, pesticides


e-GIGI ◽  
2015 ◽  
Vol 3 (1) ◽  
Author(s):  
Olyvia Octaviany Monoarfa ◽  
Karel Pandelaki ◽  
Christy N. Mintjelungan

Abstract: Diabetes Mellitus (DM) is a metabolic disease group with the characteristic blood glucose levels than normal (hyperglycemia) that occurs because abnormalities in insulin secretion, insulin recognized when payable disorders, or combination of both. Regular blood glucose levels cause patients uncontrolled type 2 diabetes are at greater risk for experiencing problems of oral health, including gingivitis. Purpose of this research was to know the description of gingival status in patients of type 2 diabetes at RSU GMIM Pancaran Kasih Manado. This research is an observational descriptive with cross sectional study approach. The research population is all patients of type 2 diabetes outpatient clinic Interna RSU GMIM Pancaran Kasih Manado in September 2014. The research method is by using a Consecutive sampling with a sample of 100 people. The result of this research showed that the gingival status in patients of type 2 diabetes calculated based gingival index that most occur severe gingivitis was 45 respondents (45%). The gingival status that showed the severe gingivitis in patients of type 2 diabetes based on age 17 respondents (48,6%) in the age range of 51-60 years old, based on gender that most occur in women 27 respondents (49,1%), based on duration of suffering 25 respondents (55,6%) in the age range >10 years, and based on blood glucose control (HbA1c) that most numerous in patients with poor blood glucose 30 respondents (60%). Conclusion: The gingival status in patients of type 2 diabetes most occur severe gingivitis, and recommended in patients of type 2 diabetes to improve their healthy lifestyle in order to normalize blood glucose levels so as to reduce the occurrence of diabetes, more attention and maintain oral hygiene, especially the gingival health.Keywords: gingival status, patients of type 2 diabetes.Abstrak: Diabetes Melitus (DM) adalah suatu kelompok penyakit metabolik dengan karakteristik kadar glukosa darah yang melebihi normal (hiperglikemia) yang terjadi karena kelainan sekresi insulin, gangguan kerja insulin, ataupun kombinasi dari keduanya. Kadar gula darah yang tidak terkontrol menyebabkan penderita DM tipe 2 beresiko lebih tinggi mengalami masalah kesehatan mulut, termasuk gingivitis. Penelitian ini bertujuan untuk mengetahui gambaran status gingiva pada penderita Diabetes Melitus tipe 2 di Rumah Sakit Umum GMIM Pancaran Kasih Manado. Penelitian ini merupakan penelitian deskriptif observasional dengan pendekatan cross sectional study. Populasi penelitian yaitu seluruh pasien DM tipe 2 rawat jalan di Poliklinik Interna Rumah Sakit Umum GMIM Pancaran Kasih Manado pada bulan September 2014. Metode penelitian yaitu Consecutive sampling dengan sampel penelitian berjumlah 100 orang. Hasil penelitian menunjukkan bahwa status gingiva yang dihitung berdasarkan indeks gingiva paling banyak menunjukkan gingivitis berat 45 subjek penelitian (45%). Status Gingiva berdasarkan umur paling banyak 17 subjek penelitian (48,6%) pada rentang umur 51–60 tahun, berdasarkan jenis kelamin paling banyak pada perempuan 27 subjek penelitian (49,1%), berdasarkan lamanya menderita paling banyak selama >10 tahun 25 subjek penelitian (55,6%), dan berdasarkan kontrol gula darah (HbA1c) paling banyak pada pasien dengan kontrol gula darah buruk (>9%) 30 subjek penelitian (60%). Simpulan: Penderita DM tipe 2 di Rumah Sakit Umum GMIM Pancaran Kasih Manado paling banyak mengalami gingivitis berat, serta disarankan bagi penderita agar lebih meningkatkan pola hidup sehat guna menormalkan kadar glukosa darah sehingga dapat mengurangi terjadinya diabetes, lebih memperhatikan dan menjaga kebersihan gigi dan mulut, terutama kesehatan gingivanya.Kata kunci: status gingiva, penderita diabetes melitus tipe 2


2019 ◽  
Vol 6 (3) ◽  
pp. 706
Author(s):  
K. N. S. V. Chalapathi Rao ◽  
Ashok Vankayala ◽  
Suresh Babu Sayana ◽  
D. S. S. K. Raju

Background: Several observational studies, well controlled randomized trials and meta-analyses reported that patients treated with statins has high risk of new onset diabetes mellitus (NODM), but the exact incidence and mechanism is still unclear and controversy. The present study was planned to find out the incidence of prediabetes and NODM and possible mechanism of action.Methods: This was a prospective, cross‑sectional study carried out at the Department of General Medicine for a period of one and half year between August 2017 and February 2019. Normoglycemic patients whose fasting blood glucose levels below 100 mg/dL and at least one year of treatment with statins were recruited in the study. Glycaemic status, development of prediabetes and NODM and insulin resistance were the primary outcomes whereas lipid profile, adverse drug effects of statins were secondary outcomes. Collected data was analysed by suitable statistical methods.Results: A total of 146 patients were recruited and 120 completed the entire study. Mean fasting blood glucose levels before initiation of statin therapy was 89.45±10.21. After one year of statin therapy, patients were separated as prediabetics and new onset diabetics and there mean fasting blood glucose levels were 116.24±12.86 (n=10) and 152.44±20.12 (n=12) respectively. A total of 12 (10.0%) patients were developed NODM and 10 (8.2%) patients developed prediabetes at the end of statin therapy. Atorvastatin 40mg was most frequency prescribed statin followed by Atorvastatin 20mg. A total of 70 (58.3%) study participants developed mild to moderate drug related adverse effects (ADRs), statin‑induced myalgia (55.7%) was the most common ADR.Conclusions: Patients treatment with statins had developed prediabetes and NODM. Atorvastatin 40mg and greater dose significantly induced NODM. Fasting blood glucose levels should be measured periodically with prescription contains higher doses of statins.


2019 ◽  
Vol 5 (3) ◽  
pp. 162
Author(s):  
Sofiannisa Achmadila ◽  
Kristianningrum Dian Sofiana ◽  
Yudha Nurdian

The use of organophosphate pesticides by farmers can cause long-term health risks, one of which is an increase in blood glucose levels. This study aims to determine whether there is a relationship between the levels of cholinesterase as an indicator of exposure to organophosphate pesticides and blood glucose of farmers in Sukorambi Village, Jember Regency. Secondary data in the form of general characteristics of the sample were obtained through interviews, while the primary data was obtained from examining the levels of cholinesterase and blood glucose levels of farmers at the Biochemical Laboratory of the Faculty of Medicine, Jember University. The research method is observational-analytic with cross-sectional study design. Based on the results of statistical analysis using the Spearman correlation test (p = 0.05), it was concluded that there was no significant relationship between the two variables (p = 0.0802).


2021 ◽  
Vol 10 (5) ◽  
pp. e10910514369
Author(s):  
Anderson Sola Haro ◽  
Thiago dos Santos Rosa ◽  
Hugo de Luca Corrêa ◽  
Rodrigo Vanerson Passos Neves ◽  
Michel Kendy Souza ◽  
...  

Background: Patients with chronic kidney disease (CKD) often present with comorbidities like hypertension and diabetes. These conditions are often associated with loss of strength, which is a strong predictor of mortality. In this sense, it is reasonable to investigate genetic and physiological markers that could be related to strength and identify variables associated with this phenomenon. Objective: This study aimed to investigate the influence of angiotensin-1 converting enzyme (ACE) and angiotensinogen (AGT) M235T polymorphisms, and blood glucose on handgrip strength (HGS) for CKD patients with and without diabetes mellitus (DM). Methods: Male patients (n = 84) participated in this cross-sectional study. Patients were grouped based on the diagnosis of DM or not.  We evaluated HGS using a dynamometer and ACE and AGT polymorphism by polymerase chain reaction. Results: There were differences in HGS between groups. Follow up analyses indicated a difference in the distribution of ACE polymorphism alleles was associated with the reduction in HGS in the DM group. The same response was present for AGT. A negative correlation existed between blood glucose levels and HGS (r = -0.334 with p < 0.05). Discussion: The present data suggests that there is a relationship between physical capacity and poor glycemic control. Conclusion: Our study demonstrated that blood glucose levels are associated with HGS in patients with CKD independent of ACE I/D and AGT M235T polymorphisms. Presence of DM may influence functional strength retention.


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