scholarly journals Association between Dietary Magnesium Intake and Glycemic Markers in Ghanaian Women of Reproductive Age: A Pilot Cross-Sectional Study

Nutrients ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 4141
Author(s):  
Helena J. Bentil ◽  
Alyssa M. Abreu ◽  
Seth Adu-Afarwuah ◽  
Joseph S. Rossi ◽  
Alison Tovar ◽  
...  

Low magnesium intake has been shown to be associated with an increased risk of type 2 diabetes mellitus (T2DM) in several studies conducted in high-income countries. However, very few studies have been performed in Africa, where many countries have a growing rate of T2DM. We conducted a pilot cross-sectional study among 63 women in Ghana to investigate the association between magnesium intake and glycemic markers. We assessed dietary magnesium using a food frequency questionnaire and glycemic markers using fasting blood glucose and glycated hemoglobin A1c (HbA1c). Our findings showed that the mean magnesium intake was 200 ± 116 mg/day. The prevalence of T2DM was 5% by measuring fasting blood glucose and 8% by measuring HbA1c. Unadjusted linear regression models revealed that higher magnesium intake significantly predicted higher fasting blood glucose levels (β = 0.31; 95% CI: 0.07, 0.55; p = 0.01) and HbA1c levels (β = 0.26; 95% CI: 0.01, 0.51; p = 0.04). In adjusted analyses, magnesium intake was no longer significantly associated with either fasting blood glucose levels (β = 0.22; 95% CI: −0.03, 0.46; p = 0.08) or HbA1c levels (β = 0.15; 95% CI: −0.08, 0.39; p = 0.20). In conclusion, our study did not show a significant association between magnesium intake and glycemic markers in women of reproductive age in Ghana. The results of this study need to be further substantiated because this was the first study to examine magnesium intake and glycemic markers in this population in Africa.

2021 ◽  
Vol 17 (4) ◽  
pp. 157
Author(s):  
Ni Ketut Sutiari ◽  
Ali Khomsan ◽  
Hadi Riyadi ◽  
Faisal Anwar ◽  
Desak Putu Yuli Kurniati ◽  
...  

Health status and micronutrient intake among vegetarian and non-vegetarian in BaliBackground: Several studies have reported that vegetarian diets have health benefits for those adopting the diets.Objective: This study aimed to compare anemia status and micronutrient intake between vegetarians and non-vegetarians in Bali.Methods: This cross-sectional study was conducted in Bali. A total of 240 samples consisting of 160 vegetarians and 80 non-vegetarians were randomly selected. Hemoglobin (Hb) and fasting blood sugar levels were measured using the cyanmethemoglobin method and enzymatic colorimetric, respectively. Meanwhile, the data on micronutrient intakes were collected by interviews using the semi-quantitative food frequency questionnaire (SQFFQ). The data were analyzed using descriptive statistics, and the Mann-Whitney test was performed to analyze the differences.Results: The study’s results showed that the mean Hb levels in the vegetarian group were significantly lower than non-vegetarians (p=0.002; p<0.05), and the anemia status in vegetarian women were higher (22.5%) than non-vegetarian women (2.5%). The mean fasting blood glucose level in non-vegetarians was significantly higher than in the vegetarian group (p=0.000; p<0.05). There were no differences in zinc (Zn) intake between vegetarians and non-vegetarians, but there were significant differences (p<0.05) in vitamin C, vitamin D, vitamin B12, folic acid, magnesium (Mg), calcium (Ca), and iron (Fe) intakes.Conclusions: There were differences in anemia status and fasting blood glucose levels between vegetarians and non-vegetarians. The fasting blood glucose levels of non-vegetarians were higher than vegetarians, and there were differences in the intake of certain micronutrients between vegetarians and non-vegetarians.


2019 ◽  
Vol 6 (3) ◽  
pp. 706
Author(s):  
K. N. S. V. Chalapathi Rao ◽  
Ashok Vankayala ◽  
Suresh Babu Sayana ◽  
D. S. S. K. Raju

Background: Several observational studies, well controlled randomized trials and meta-analyses reported that patients treated with statins has high risk of new onset diabetes mellitus (NODM), but the exact incidence and mechanism is still unclear and controversy. The present study was planned to find out the incidence of prediabetes and NODM and possible mechanism of action.Methods: This was a prospective, cross‑sectional study carried out at the Department of General Medicine for a period of one and half year between August 2017 and February 2019. Normoglycemic patients whose fasting blood glucose levels below 100 mg/dL and at least one year of treatment with statins were recruited in the study. Glycaemic status, development of prediabetes and NODM and insulin resistance were the primary outcomes whereas lipid profile, adverse drug effects of statins were secondary outcomes. Collected data was analysed by suitable statistical methods.Results: A total of 146 patients were recruited and 120 completed the entire study. Mean fasting blood glucose levels before initiation of statin therapy was 89.45±10.21. After one year of statin therapy, patients were separated as prediabetics and new onset diabetics and there mean fasting blood glucose levels were 116.24±12.86 (n=10) and 152.44±20.12 (n=12) respectively. A total of 12 (10.0%) patients were developed NODM and 10 (8.2%) patients developed prediabetes at the end of statin therapy. Atorvastatin 40mg was most frequency prescribed statin followed by Atorvastatin 20mg. A total of 70 (58.3%) study participants developed mild to moderate drug related adverse effects (ADRs), statin‑induced myalgia (55.7%) was the most common ADR.Conclusions: Patients treatment with statins had developed prediabetes and NODM. Atorvastatin 40mg and greater dose significantly induced NODM. Fasting blood glucose levels should be measured periodically with prescription contains higher doses of statins.


2018 ◽  
Vol 5 (3) ◽  
pp. 1092 ◽  
Author(s):  
Rameshwar Ninama ◽  
Chakshu Chaudhry ◽  
Rameshwar Lal Suman ◽  
Suresh Goyal ◽  
Ramprakash Prakash Bairwa ◽  
...  

Background: Diarrhea is the major cause of death in children below five years of age. Hypoglycemia has been a potential fatal complication of infectious diarrhea in both well-nourished and poorly nourished children. But prevalence of hypoglycemia in diarrheal dehydration is not exactly known. This study was done to evaluate the glycemic status in children having acute diarrhea with dehydration and specifically associated with severe acute malnutrition (SAM).Methods: This descriptive cross-sectional study was conducted during July 2017 to December 2017 at Bal Chikitsalaya Udaipur, Rajasthan, India. Blood glucose levels were assessed in 150 children of acute diarrhea with dehydration, comprising of 100 SAM and 50 Non SAM children.Results: Average blood glucose of SAM children was 89 mg/dl and of non-SAM, it was 120 mg/dl. Average blood glucose was low in SAM as compared to non-SAM in both some dehydration (116.08±21.26) and severe dehydration (66.69±19.80) as well as with or without ORS intake. Overall 18 (12%) of children had hypoglycemia and all were in severe dehydration and not taking ORS. Blood glucose levels were statistically low in severe dehydration and those who were not taking ORS at the time of hospitalization (p = 0.001). In severe dehydration 25% of children had hypoglycemia means every fourth child had low blood glucose <54 mg/dl.Conclusions: Overall prevalence of hypoglycemia is 12% in diarrheal dehydration and 20% in SAM with dehydration. Twenty five percent of severe dehydration children had hypoglycemia, and all have not started ORS. None of the child started ORS developed hypoglycaemia.


Author(s):  
Meiriani . ◽  
Yuneldi Anwar ◽  
Puji Pinta Omas Sinurat

Background: Diabetes and higher HbA1c level have increased the incidence of stroke. Hemoglobin levels both high and low are associated with poor outcomes. Leukocytes play an important role in the initiation of the atherosclerosis process.Methods: This was a cross-sectional study with a sample size of 62 people selected by non-random sampling method on a consecutive basis, patients with acute stroke were taken blood to measure blood glucose levels, HbA1c, Hb and Leucocytes when entering the hospital room. Outcomes were assessed using NIHSS and MRS. The calculation of NIHSS and MRS scores was performed on the first day of admission and the fourteenth day. To analyze the correlation of blood sugar levels during HbA1c, Hb and leukocytes in acute stroke, this study used Spearman's correlation test. The p value <0.05 was considered statistically significant.Results: The study subjects of 62 acute stroke patients (acute ischemic stroke 31 people and 31 people hemorrhagic stroke). Acute stroke patients were consisted of 38 men (61.3%) and 24 women (38.7%). Of 31 people with hemorrhagic stroke, there were 16 men (51.6%) and 15 women (48.4%), ischemic stroke patients were consisted of 22 people (71, 0%) and women were 9 people. Spearrman repair test showed no symptoms between blood glucose levels, HbA1c, Hemoglobin and leukocytes with outcomes in acute stroke.Conclusions: There was no significant association between blood glucose levels, HbA1c, hemoglobin and leukocytes with outcomes in acute stroke.


2020 ◽  
Vol 8 (3) ◽  
pp. 247
Author(s):  
Siti Cholifah ◽  
Paramitha Amelia Kusumawardani ◽  
Miftahul Muslih

<em>Efforts to limit and regulate birth spacing as a goal to create quality families and healthy families, the government encourages people to use contraceptives as birth control. One of these contraceptives is injection contraception. Injecting contraception is the most widely used contraceptive tool by the people of Indonesia, is considered effective, practical, but has several side effects, the most worrying is that it affects blood glucose. Blood glucose levels in the human body that increase more than normal can be a symptom of diabetes mellitus. The purpose of this study is to determine differences in blood glucose levels in progestin injection and combined injection contraceptive acceptors. Observational research design using a cross sectional approach. The study population was all injectable acceptors. Samples were taken that met the inclusion criteria, namely respondents were willing to be examined, there was no history of diabetes mellitus (DM), less than 40 years of age, acceptors of at least 6-8 hours fasting. Sampling was carried out using consecutive sampling techniques totaling 50 acceptors (25 progestin injection acceptors, 25 combined injection acceptors). Data were analyzed by Witney mann test using α = 0.05. The results showed the mean fasting blood glucose for progestin injection acceptors was higher than for combination injections, the test results P = 0.008 &lt;α = 0.05. The conclusions of the study show that there are significant differences in blood glucose levels in progestin-injecting acceptors and this combination means that progestin-injecting contraceptives have a higher impact on increasing fasting blood sugar levels compared with combined injection contraception. Suggestions for health workers to control blood glucose injector acceptors at acceptors who experience high glucose levels are recommended to replace non-hormonal contraceptive methods.</em>


2017 ◽  
Vol 6 (4) ◽  
pp. 285
Author(s):  
Nur Rochmah ◽  
Enny Probosari ◽  
Fillah Fithra Dieny

Background : Vitamin D and calcium have metabolic functions in the cells and insufficient intake has been proven to increase the risk factor for many chronic diseases, such as diabetes mellitus. Vitamin D and calcium both contribute in raising insulin secretion by regulating extracelullar calcium concentration and fluxing through cell membranes facilitated by calcium-sensing receptor. This study aimed to determine correlation between vitamin D and calcium intake with blood glucose levels in obese woman aged 45-55 years.Methods : Observational study with cross sectional design. Sixty subjects were selected using consecutive sampling. Food intakes were assessed by Semi Quantitative Food Frequency Questionnaire, fasting blood glucose levels were measured by Glucose Oxidation method, and physical activities were determined by Long International Physical Activity Questionnaire. The data were analyzed using r Pearson and Rank-Spearman test. Results : Mean of fasting blood glucose levels was 90,4±37,22 mg/dL with average vitamin D was 4,1 ±2,23 μg, whereas calcium was 547,7±316,24 mg. All subjects had low vitamin D intake; 88,3% subjects had low calcium intake; 88,3% subjects had normal fasting blood glucose; and 11,7% subjects had hyperglycemia. There was no correlation between vitamin D (p = 0,295) and calcium  (p = 0,295) intake with fasting blood glucose levels. Intake of energy, carbohydrate, fat, protein, fiber  and physical activity also showed no corerelation with fasting blood glucose levels. Conclusion : There was no correlation of vitamin D and calcium intake with fasting blood glucose levels in obese woman aged 45-55 years.


2019 ◽  
Vol 1 (2) ◽  
pp. 41-45
Author(s):  
Suratno Suratno ◽  
Novidha Muji Rahayuningrum ◽  
Helmus Helmus

Alcohol consumption is often associated with the incidence of diabetes mellitus. This study aimed to examine fasting blood glucose levels and alcohol consumption in men in Mendawai, Palangka Raya, Central Kalimantan. The cross-sectional study design was carried out to asses fasting blood glucose levels on 20 male alcohol drinkers. Blood glucose assay was determined by an automated enzymatic colorimetric technique using Photometers (5010 V5+ Robert Riele). Determination of fasting blood glucose level using glucose oxidase and peroxidase (GOD-POD) method. This study found that 40% of alcohol drinker considered high fasting blood glucose level with an average level of 139.6 mg/dL. Twenty-five percent of alcohol drinkers regarded as low fasting blood glucose level with an average of 68.8 mg/dL. And 35% of drinkers have a normal level of fasting blood glucose with an average of 97.4 mg/dL


Jurnal GIZIDO ◽  
2018 ◽  
Vol 10 (2) ◽  
pp. 101-107
Author(s):  
Olga Lieke Paruntu ◽  
Nonce Nova Legi ◽  
I Made Djendra ◽  
Giantri Kaligis

Diabetes mellitus is very influential on the quality of human resources and has a significant impact on health costs. This diabetes mellitus cannot heal but can only be controlled. Patients with diabetes mellitus are not able to produce enough insulin or do not use it effectively so that there is excess glucose in the blood. One of the factors that triggers glucose is an unhealthy diet such as rarely consuming fiber, as well as consuming micronutrients, including magnesium. The general objective of this study was to determine the effect of fiber and magnesium intake with fasting blood glucose levels in type 2 diabetes mellitus patients at Pancaran Kasih General Hospital GMIM Manado. This research method using cross sectional design by purposive sampling. Data collection about the intake of fiber and magnesium using the 24-hour recall and the results of the examination of fasting blood glucose levels were taken through the medical record of the patient. Analyst data using logistic regression analysis. Based on data analysis using Fisher's Exact Test, showed P value = <0.05 / P = 0.013 means that there is a relationship between fiber intake and fasting blood glucose levels. While the results of data analysis using Fisher's Exact Test, showed P value => 0.05 / P = 0.61, meaning that there was no correlation between magnesium intake and fasting blood glucose levels. It can be concluded that there is a relationship between fiber intake and blood glucose levels. There is no relationship between magnesium intake and fasting blood glucose levels.


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