The study of pulmonary function tests in patients with hypothyroidism

Background: Hypothyroidism is a common disease with a prevalence rate of 11% in India. It affects all organ systems in the body. Patients with hypothyroidism frequently have symptoms of fatigue and exercise intolerance. These symptoms could arise from a reduced pulmonary reserve, cardiac reserve or decreased muscle strength or increased muscle fatigue. This study aims to study the pulmonary function test in patients with hypothyroidism.Methods: This is a cross sectional study conducted on 100 patients divided into 2 groups (a) newly detected hypothyroids (b) normal control group. Cases were matched with controls in having similar environment exposure and age group. All patients had routine symptom and clinical assessment. Laboratory investigations such as complete blood picture, pulmonary function test, chest x ray and thyroid function test were done. Data was entered and analysed.Results: In this study conducted on 100 patients, case group had symptoms of easy fatiguability (36%), breathlessness (20%), menstrual abnormality (20%), weight gain (7%) and generalised body aches (5%). Mean FEV1 levels between cases and controls were 1.34 and 1.72 (p value 0.00), mean FVC were 1.88 and 2.09 (p value 0.114), FEV1/FVC ratio of 70.56, 81.98 respectively (p value 0.00). The distribution of PFT pattern was 32% obstructive, 28% mixed pattern and 22% restrictive pattern.Conclusions: This study shows that hypothyroidism causes significant decrease in FEV1 and FEV1/FVC ratio, thereby suggesting obstructive patterns of lung involvement .Therefore PFT can be used routinely as a screening test for all hypothyroid patients to detect early respiratory dysfunction and thereby optimise treatment especially in obese patients and patients with pre-existing lung disease as hypothyroidism adds to their respiratory dysfunction.

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Correlation of Height Parameter and Pulmonary Function Test with Grade of Allergic Rhinitis and Asthma in Children

International Journal of Innovative Research in Medical Science ◽

10.23958/ijirms/vol05-i08/937 ◽

2020 ◽

Vol 5 (08) ◽

pp. 349-352

Author(s):

Sadaf Choudhary ◽

Keya Rani Lahiri ◽

Fehmida Najmuddin

Keyword(s):

Allergic Rhinitis ◽

Pulmonary Function ◽

Pulmonary Function Test ◽

Pulmonary Function Tests ◽

Persistent Asthma ◽

P Value ◽

Function Tests ◽

Function Test

Introduction: Allergic Rhinitis and Asthma adversely affects height in children and it could be considered as an objective tool to assess severity, compliance and lung functions in children. We studied the correlation between height and pulmonary function tests with classification of allergic rhinitis and asthma. Aims & Objectives: 1) To study the height parameter with the grade of asthma and allergic rhinitis 2) To evaluate the pulmonary function test with the severity of asthma and allergic rhinitis 3) To correlate height and pulmonary function test with the classification of asthma and allergic rhinitis. Material and Methods: A prospective study including 30 patients in the age group of 5-12 years diagnosed with allergic rhinitis (AR) and bronchial asthma was conducted in a private tertiary care hospital in Navi Mumbai. History was entered in a pre-designed proforma and height was measured using a calibrated stadiometer along with pulmonary function tests recorded at the initial and two visits, 3 months apart. Results: Height increased significantly in patients without AR (p-value<0.01), with mild intermittent (p-value=0.02) and mild persistent AR (p-value<0.01) on subsequent visits. Patients with intermittent, mild persistent and moderate persistent asthma showed a statistically significant increase in height (p-value<0.01) with subsequent assessments. No significant increase in height was noted in patients with moderate persistent AR (p-value=0.14) and severe persistent asthma (p-value=0.16). At baseline, the height correlated significantly with FEV1 (p value<0.01), FVC (p value<0.01), Pre and Post-PEFR (p value<0.01, each). This trend continued at the first follow up. At the second follow-up, height correlated significantly with all parameters of pulmonary function tests (p value<0.01 for FEV1, FVC, FEV1/FVC ratio and PEFR). Conclusion: Height correlation with classification of AR and Asthma along with pulmonary function test has emerged as a simple, safe, cost-effective method in assessing control and monitoring the disease.

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Medium-Term Pulmonary Function Test After Thoracoscopic Lobectomy and Segmentectomy for Congenital Lung Malformation: A Comparative Study With Normal Control

Frontiers in Pediatrics ◽

10.3389/fped.2021.755328 ◽

2021 ◽

Vol 9 ◽

Author(s):

Jin-Xi Huang ◽

Song-Ming Hong ◽

Jun-Jie Hong ◽

Qiang Chen ◽

Hua Cao

Keyword(s):

Pulmonary Function ◽

Pulmonary Function Test ◽

Small Airway ◽

Normal Lung ◽

Control Group ◽

Medium Term ◽

Thoracoscopic Lobectomy ◽

Congenital Lung Malformation ◽

Significant Difference ◽

Function Test

Purpose: This study aimed to compare the outcomes and pulmonary function test (PFT) of thoracoscopic segmentectomy and lobectomy in infants with congenital lung malformation and study the result of PFT on a medium-term basis.Methods: The clinical data of 19 infants with congenital lung malformation who underwent thoracoscopic surgery in our hospital from January 2018 to March 2019 were retrospectively studied; these infants were paired with another 19 infants who underwent thoracoscopic lobectomy during the same period using propensity score matching. Age-matched healthy individuals with similar body sizes were recruited for PFT as the control group. Patient characteristics, postoperative PFT, and outcomes were extracted for statistical analysis.Results: The average length of hospital stay did not significantly differ between segmentectomy and lobectomy groups. The segmentectomy group had more chest tube drainage than the lobectomy group. PFT 1 month after the operation showed that the tidal volume of the lobectomy group was lower than that of the segmentectomy group. Time to peak expiratory flow/time of expiration and peak flow/terminal airway velocity (V25%) indicated small airway dysfunction in the lobectomy group, and no obvious abnormalities were found in “time of inspiratory/time of expiration” in either group. Reexamination of pulmonary function 2 years after the operation showed that the small airway function of the segmentectomy group returned to normal, and no significant difference in pulmonary function was noted among the three groups.Conclusion: The short-term pulmonary function recovery was better after segmentectomy than after lobectomy. Patients who underwent thoracoscopic lobectomy and segmentectomy have normal lung function 2 years after the operation.

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Assessment of pulmonary function test in type 2 diabetes mellitus and its correlation with their HbA1c levels

International Journal of Advances in Medicine ◽

10.18203/2349-3933.ijam20190109 ◽

2019 ◽

Vol 6 (1) ◽

pp. 164

Author(s):

Archana Toppo ◽

Kulvant Singh Ajamani

Keyword(s):

Diabetes Mellitus ◽

Pulmonary Function ◽

Pulmonary Function Test ◽

Small Sample Size ◽

Type Ii Diabetes Mellitus ◽

Small Sample ◽

Control Group ◽

Endogenous Insulin ◽

Function Test ◽

Restrictive Pattern

Background: Diabetes mellitus (DM) is a group of metabolic disorders characterized by hyperglycemia and deranged metabolism of carbohydrates, lipids and protein that result from insensitivity to endogenous insulin. It is a substantial global health problem and markedly increases morbidity and mortality of the affected people.Methods: The present study was conducted in the Department of medicine Dr. B.R.A.M. Hospital, Raipur. Total 67 subjects with type II diabetes mellitus as per WHO criteria of diabetes mellitus, aged between 18-60years of both sexes were included in the study. Patients FBS, PPBS were analysed by glucose oxidase (GOD), peroxidase (POD) methods in ILAB 650 analyser and HbA1C was analysed using HPLC. Pulmonary function test was conducted in all the subjects using the spirometer which is the gold standard for accurate and repeatable measurement of lung function.Results: Majority of the subjects were male (36, 53.7%) and belonged to age group of 51-60years (n=34, 50.7%), Duration of DM </=10years (n=47, 70.1%), restrictive pulmonary function in 10 (14.9%) subjects. Correlation of age with a restrictive pattern of PFT (P=0.013*) and with duration of diabetes (P<0.0001**). Pulmonary function test parameters having mild downstream correlation with diabetes mellitus.Conclusions: Diabetes was more common in the sixth decade of life with slight male preponderance. The short-term indicators of glycaemic controls were not significantly associated with a restrictive pattern of PFT. Despite the best effort, there are limitations of this study, which includes small sample size, author have not taken general population, and lack of a control group. These limitations can be overcome in the future studies.

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THE THE NEGLECTED ASSOCIATION OF LUNGS AND GLYCEMIC CONTROL.

International Journal of Medical and Biomedical Studies ◽

10.32553/ijmbs.v4i2.917 ◽

2020 ◽

Vol 4 (2) ◽

Author(s):

Dona Das ◽

R.V. Sridhar ◽

Midun Chandar

Keyword(s):

Glycemic Control ◽

Early Diagnosis ◽

Pulmonary Function ◽

Pulmonary Function Test ◽

Rural Population ◽

Target Organ ◽

The Body ◽

Lung Involvement ◽

Multiple Organs ◽

Function Test

The awareness of diabetes and its increasing complications remain hidden and often diagnosed stage at a later stage in India, especially among the rural population. Diabetes is known to affect multiple organs in the body but lung as a target organ has not been highlighted enough. Pulmonary Function Test is an important tool in the early diagnosis of lung involvement in diabetes, however its availability and utility among the mass population in India is not abundant.

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Study of pulmonary function test in asymptomatic smokers and non-smokers between 30-50 years of age in a tertiary care hospital

International Journal of Advances in Medicine ◽

10.18203/2349-3933.ijam20172601 ◽

2017 ◽

Vol 4 (4) ◽

pp. 959

Author(s):

Kekhrielhouto Sophie ◽

Neelima Singh ◽

Avinash John Dharvey

Keyword(s):

Pulmonary Function ◽

Pulmonary Function Test ◽

Tertiary Care ◽

Significant Risk ◽

Uncontrolled Hypertension ◽

Chronic Obstructive ◽

P Value ◽

Care Hospital ◽

Age Group ◽

Function Test

Background: Tobacco smoking is widely prevalent all over the world and it continues to rise in developing countries. Smoking has a deleterious effect on pulmonary functions. Smoking is the single most significant risk factor contributing to the development of Chronic obstructive airway diseases (COPD). Spirometry by a trained health professional gives an indication of lung health by measuring airway abnormality. Objectives were to study pulmonary function test (PFT) in smokers and non-smokers between 30-50 years and to study the correlation of PFT with pack years.Methods: Apparently healthy subjects, 50 smokers and 50 non-smokers between 30-50 years without any symptoms were included as subjects. Patients with uncontrolled hypertension, recent myocardial infarction and pulmonary TB were excluded. Ex-smokers were excluded from the study. Patients with acute respiratory illness, severe systemic illness, chest trauma and dementia were also excluded. After proper history taking and clinical examination, measuring height and weight (vitals, pulse rate, respiratory rate, blood pressure) the selected individual was subjected to spirometry using ATS criteria (American Thoracic Society criteria). Spirometry was performed using UNI-EM spirometer. Collected data was analyzed using Statistical Package for the Social Service (SPSS) software version 17.Results: In this study 94 males and 6 females were enrolled as subjects. Maximum number of the patient 49 cases (49%) presented in the age group of 30-35 years, followed by 23 cases (23%) in 36-40 years age group. Of these 49 cases,15 were smokers while the rest 34 were non-smokers (P=0.0007). In 100 cases studied, 39% showed normal PFT and 61% shows abnormal PFT. Among smokers (out of total 50 cases) pulmonary function test (PFT) was abnormal in 36 cases (72%) while in non-smokers, 25 (50%) had abnormal PFT (P-value-0.024). This data indicates that smoking is highly associated with an abnormal PFT pattern. Out of 100 cases both smokers and non-smokers, 11 (73.33%) underweight cases with (BMI<18.4) showed abnormal PFT. In 50 smokers, maximum cases 29 (58%) had normal BMI (18.5-22.9) (P value 0.0002). Abnormal PFT was observed in 25 (50%) non-smokers (P=0.001). Abnormal PFT was seen in 30 (69.77%) smokers with pack years <15 and 6 smokers (85.6%) with pack years >15 (P-value 0.383).Conclusions: Smoking is common in males between 30-35 years age group. Smoking is highly associated with an abnormal PFT. Cessation of smoking should be encouraged and PFTs from time to time in asymptomatic adults both smokers and non-smokers will be useful for early identification of abnormalities.

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EFFECT OF ERGONOMIC GYMNASTIC ON BLOOD PRESSURE AND LIPID PROFILE HYPERTENSION PATIENT AT SUMBER AGUNG VILLAGE, JATIREJO DISTRICT, MOJOKERTO CITY, INDONESIA

INTERNATIONAL JOURNAL OF NURSING AND MIDWIFERY SCIENCE (IJNMS) ◽

10.29082/ijnms/2017/vol1.iss1.24 ◽

2017 ◽

Vol 1 (1) ◽

pp. 14-25

Author(s):

Eka Nur Soemah ◽

Agus Hariyanto ◽

Amar Akbar

Keyword(s):

Blood Pressure ◽

Lipid Profile ◽

Total Cholesterol ◽

T Test ◽

The Body ◽

Control Group ◽

P Value ◽

Common Disease ◽

Sample Number ◽

Hypertension Patient

Background : Hypertension is the most common disease found in the community. It does not only degrade the quality of life, but it can be life-threatening. Hypertension is known as heterogeneous group of disease because it can affect anyone from different age groups and various economic classes. There are two therapies for hypertension ie pharmacology and nonpharmacology. One of non-pharmacology therapy is doing ergonomic gymnastics. The purpose of this study is to see the effect of ergonomic gymnastics on blood pressure in people with hypertension in Sumber Agung Village, Jatirejo Sub-district, Mojokerto Regency. Method : This research method used one group pre test - post test design with control group. Sampling technique used was simple random sampling, from 80-person population of hypertension patient in Sumber Agung Village Jatirejo Sub-district Mojokerto Regency and become sample number 20 respondents in treatment group, and 20 respondents in control group according to criteria. Data collection using interval scale blood presure and total cholesterol. Analysis using statistical test Paired T test and Independent T-test SPSS 17. Result : From the analysis we got result p value 0,00 <0,05 it indacted that means of blood presure and lipid profile before ergonomic gymnastic and after ergonomic gymnastic shown significat value, it means that ergonomic gymnastic was very effective for blood pressure and lipid profile (total cholesterol). Discussion : Ergonomic gymnastics is one of effective therapy, easy to do and useful. Because ergonomic gymnastics can make the body become relaxed and blood vessels become vasodilated so that the blood flow and oxygen supply becomes smooth and it get impact in lipid profile . keywords : Aergonomic Gymnastic, Blood Pressure, Lipid Profile, Hipertension.

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CORRELATION OF PHYSICAL ACTIVITY AND PULMONARY FUNCTION TEST IN FIRST YEAR MEDICAL STUDENTS IN A TERTIARY CARE CENTRE.

10.36106/gjra/3916620 ◽

2021 ◽

pp. 243-245

Author(s):

Anuradha Upadhyay ◽

Kavita Yadav ◽

Rajesh Kumar Sharma

Keyword(s):

Physical Activity ◽

Medical Students ◽

Pulmonary Function ◽

Pulmonary Function Test ◽

Acute Exercise ◽

Tertiary Care ◽

The Body ◽

Respiratory Parameters ◽

Function Test ◽

Before And After

BACKGROUND: Measurements of the ventilatory adaptations to physical activity provide useful information about the functional conserve capacity of the lungs in study participants with respiratory diseases. AIM: The present study aimed to study the correlation of physical activity and pulmonary function test in rst year MBBS medical students MATERIALS AND METHODS: A cross-sectional study conducted in a medical college. A total of 80 participated students comprising of 40 males and 40 females in the age group of 18-21 years were divided into four groups based on their body mass index as underweight, normal, overweight and obese group. Respiratory parameters (VC, FVC, FEV1, FEV1% and PEF) measured before and after acute physical activity in the bicycle ergometer. RESULTS: No signicant changes found in all the four groups before and after physical activity in males. The values of FVC & VC after exercise reduced than the baseline values in overweight and obese females (p < 0.01). CONCLUSION: Acute exercise not signicantly affect the respiratory parameters. The body fat distribution of the participated signicantly affect the ventilatory response to acute physical activity in otherwise healthy individuals

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Respiratory Dysfunction in Craniovertebral Junction Pathology: A Pulmonary Function Test Correlation

The Journal of Spinal Surgery ◽

10.5005/jp-journals-10039-1152 ◽

2017 ◽

Vol 4 (4) ◽

pp. 164-170

Author(s):

George C Vilanilam ◽

Dhananjaya I Bhat ◽

Dhaval P Shukla ◽

Hardik Siroya ◽

Talakkad N Sathyaprabha

Keyword(s):

Pulmonary Function ◽

Pulmonary Function Test ◽

Craniovertebral Junction ◽

Respiratory Dysfunction ◽

Function Test ◽

Test Correlation

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EFFECTS OF HIGH-INTENSITY INSPIRATORY MUSCLE TRAINING IN RUGBY PLAYERS

Revista Brasileira de Medicina do Esporte ◽

10.1590/1517-869220182403166216 ◽

2018 ◽

Vol 24 (3) ◽

pp. 216-219 ◽

Cited By ~ 2

Author(s):

Adauto de Oliveira Nunes Júnior ◽

Marina Andrade Donzeli ◽

Suraya Gomes Novais Shimano ◽

Nuno Miguel Lopes de Oliveira ◽

Gualberto Ruas ◽

...

Keyword(s):

Pulmonary Function ◽

Pulmonary Function Test ◽

High Intensity ◽

Inspiratory Muscle ◽

Inspiratory Muscle Training ◽

Control Group ◽

Muscle Training ◽

Level Of Evidence ◽

Function Test ◽

Rugby Players

ABSTRACT Introduction: Rugby is a sport characterized by high and low intensity motor action. Therefore, the respiratory muscles need adequate work to maintain sustained effective breathing. Objective: To analyze the effects of high-intensity inspiratory muscle training (IMT) in amateur rugby players from the city of Uberaba, Minas Gerais, Brazil. Methods: This is a clinical study in which 20 amateur players underwent a pulmonary function test, respiratory muscle strength and physical capacity assessment. The participants were divided into two groups: 10 volunteers in the IMT group (G1) and 10 in the control group (G2). All the assessments were carried out before and after 12 weeks of IMT. Results: No significant changes were observed in the pulmonary function test. However, maximal voluntary ventilation, maximal inspiratory pressure, maximal expiratory pressure and distance increased significantly after IMT. Conclusion: IMT had beneficial effects on amateur rugby players. Level of evidence I; Therapeutic studies - Investigation of treatment results.

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