scholarly journals Estimation of D-dimer levels in COVID-19 patients and its correlation with age and gender

Author(s):  
Kalash Chander

Background: COVID-19 patients show some kind of abnormal coagulation parameters, related to thrombotic disorders, which can act as marker of the disease. One such marker is D-dimer, which is a widely used fibrin degradation product test used for initial diagnosis of thrombotic disorders. D-dimer levels from patients coming in OPD of sub-district hospital Bishnah, Jammu were analyzed to estimate the degree of this relation to its severity, age and gender.Methods: A retrospective study was conducted on the D-dimer data, collected from the patients coming in OPD of sub-district hospital Bishnah, Jammu, from March 2019 to March 2020. Randomly selected 134 patients infected with COVID-19, with known age and gender and confirmed by RT-PCR were included in the study.Results: Out of these 134 patients, 76 were males (56.72%) and 58 were females (43.28%). 41.04% patients belonged to the age group 51 to 70 years; 92 patients had elevated levels of D-dimer levels, 52 (38.8%) patients showed D-dimer levels four-folds the safe level, >1000 ng/ml and a significant number of females (70.7%) were found to be with elevated D-dimer levels. Women were found to be at a higher risk of developing thrombotic disorders than men. There was slight relation of thrombotic disorders such as D-dimer with postmenopausal age of women as well.Conclusions: This study has shown a clear guidance that women and older individuals are at a higher risk of developing thrombotic disorders during COVID-19 infection. 

2021 ◽  
pp. 003329412110268
Author(s):  
Vaitsa Giannouli ◽  
Juliana Yordanova ◽  
Vasil Kolev

Research on aesthetic descriptors of art in different languages is scarce. The aim of the present study was to elucidate the conceptual structure of aesthetic experiences of three forms of art (music, visual arts and literature) in the Greek language, which has not been explored so far. It was further aimed to study if biological and cognitive factors such as age and gender might produce differences in art appreciation. A total of 467 younger and older individuals from Greece were asked to generate verbal descriptors (adjectives) in free word-listing conditions in order to collect terms reflecting the aesthetics-related semantic field of art. The capacity of verbal memory was controlled by using a battery of neuropsychological tests. Analysis of generated adjectives’ frequency and salience revealed that ‘beautiful’ was the most prominent descriptor that was selected with a distinctive primacy for all three forms of arts. The primacy of ‘beautiful’ was significantly more pronounced for visual arts relative to music and literature. Although the aging-related decline of verbal capacity was similar for males and females, the primacy of ‘beautiful’ depended on age and gender by being more emphasized for young females than males, and for old males than females. Analysis of secondary descriptors and pairs of adjectives revealed that affective and hedonic experiences are essentially fixed in the semantic field of art reflection. It is concluded that although the concept of the aesthetics seems to be diversified and rich, a clear primacy of beauty is found for the Greek cultural environment and across different forms of art. The results also highlight the presence of complex influences of biological and cognitive factors on aesthetic art experiences.


Author(s):  
Olga Albuquerque ◽  
Gillian Grace Moreira

Using questionnaires and interviews, the video-gaming habits of 136 youngsters, ranging from the ages of 9 to 15 years, were assessed, taking into consideration their age and gender. It was found that many youngsters are playing games which are not appropriate for their age group, and that long hours are spent at computer screens on these games without parental control or supervision. In fact, most parents do not even know what games their children are playing never mind whether they are rated as suitable for their age group. In addition, differences between boys and girls were significant, allowing us to confirm that boys prefer more action-oriented games while girls choose simulation games. Although the small-scale nature of this study does not allow us to generalise its conclusions, its findings are relevant and can point the way for future studies of this type. The centrality of video games in the lives of children and teenagers today is such that these and the practices they engender need to be taken into account when considering the rise of anti-social, aggressive, and at times violent attitudes and behaviours amongst youngsters.


2002 ◽  
Vol 92 (4) ◽  
pp. 1401-1408 ◽  
Author(s):  
Ghislaine Geelen ◽  
Tomi Laitinen ◽  
Juha Hartikainen ◽  
Esko Länsimies ◽  
Kim Bergström ◽  
...  

To evaluate the influence of age and gender on the neuroendocrine control of blood pressure in normal subjects, a 13-min 70° head-up tilt (HUT) was applied after 3 h of recumbency to 109 healthy men and women aged 23–50 yr ( age group I) and 51–77 yr ( age group II). We found that age and gender had a significant influence on plasma norepinephrine (PNE) concentration at baseline and in the upright position. PNE was significantly higher in older men compared with the younger men and women of both age groups, suggesting a divergent age-related activation of the sympathetic nervous system between genders at baseline as well as during a sustained orthostatic challenge. There was no significant influence of age or gender on plasma epinephrine at baseline or during HUT. Plasma renin activity was significantly higher at baseline as well as in the upright position during HUT in elderly men than in women. Age or gender had no influence on plasma vasopressin (PAVP), and, regardless of age, nonhypotensive HUT induced an extremely modest increase in PAVP. The syncopal subjects displayed a hormonal pattern associating increased PNE and a surge in plasma epinephrine and PAVP minutes before syncope during HUT. The orthostatic intolerance appears not to be a feature of healthy aging per se. In healthy subjects, both age and gender modulate markedly the cardiovascular and neuroendocrine responses to an orthostatic challenge and must be taken into consideration, particularly when catecholamine responses are studied.


2014 ◽  
Vol 17 ◽  
Author(s):  
Elena Felipe-Castaño ◽  
Benito León-del-Barco ◽  
José Antonio López-Pina

AbstractTo provide questionnaires for clinical assessment with scales adapted for adolescents would benefit clinical practice as well as research. The aim of this paper is to report normative data for adolescents on the SCL-90-R using a probability sample from the community. The participants were 1,663 adolescents, 845 girls and 818 boys, with an average age of 14.26 (SD = 1.36). They were selected through stratified cluster sampling with groups randomly selected from schools. Sampling error was estimated at 4% with a 95.5% confidence level. Cohen´s d effect sizes are reported for age-group. We found significant differences across participants according to gender and age on SCL-90-R Global Scores and Symptom Dimensions. Thus, we provide normative data, divided according to age and gender.


2003 ◽  
Vol 14 (2) ◽  
pp. 109-113 ◽  
Author(s):  
Sarah Creighton ◽  
Melinda Tenant-Flowers ◽  
Christopher B Taylor ◽  
Rob Miller ◽  
Nicola Low

A cross-sectional study of new clients with either gonorrhoea or chlamydia attending King's College Hospital in 1998. One thousand two hundred and thirty-nine women and 1141 men had gonorrhoea, chlamydia or both. Overall, 24.2% (124/512) of heterosexual men and 38.5% (136/353) of women with gonorrhoea also had chlamydia ( P<0.001). Of heterosexual males 18.8% (124/660) and 13% (136/1022) of females with chlamydia also had gonorrhoea ( P=0.002). Ethnicity had no effect on the proportion of co-infection after controlling for age and gender. Clients with dual infection were younger than those with either infection alone ( P=0.0001). Over half of women and a quarter of men aged 15 to 19 years were dually infected so testing for both gonorrhoea and chlamydia may be appropriate in this age group in settings outside genitourinary clinics. The high proportion of cases of gonorrhoea that also have chlamydia justifies the policy of epidemiological treatment for chlamydia.


2003 ◽  
Vol 27 (1) ◽  
pp. 91-94 ◽  
Author(s):  
Ali Mentes ◽  
Julide Atukeren

The aim of the study was to evaluate toothbrushing management and ability of children in relation to age and gender. The study population consisted of 75 children and were divided into three equal groups as 3-5, 6-8 and 9-11 years of age.The grip type during toothbrushing was recorded on videotape.The most preferred grip types were distal (73%) followed by power (43%) and oblique grips (29%). There were a statistically significant differences between age groups and the grip types (p&lt;0.001) but no significant difference was seen between boys and girls in grip preferences (p&gt;0.05).The mean duration of toothbrushing was shorter in 3-5 years of age group (28 seconds) than the 6-8 and 9-11 age groups (35 and 47 seconds respectively).


2011 ◽  
Vol 8 (3) ◽  
pp. 229-236 ◽  
Author(s):  
Cristina Legnani ◽  
Michela Cini ◽  
Benilde Cosmi ◽  
Paolo Carraro ◽  
Armando Tripodi ◽  
...  

2020 ◽  
Vol 11 (SPL3) ◽  
pp. 441-446
Author(s):  
Nur Liyana Hannah Binti Izham Akmal ◽  
Adimulapu Hima Sandeep ◽  
Revathi Duraisamy

Cervical lesions are often characterized by defects seen in the gingival third of a tooth crown which may be in the facial or lingual surface. Pathological loss of tooth structure caused by factors other than dental caries such as cervical abrasion is referred to as non-carious cervical lesions (NCCL). Cervical abrasion is an example of NCCL in which a constant exposure of the tooth to mechanical forces leads to pathological wearing away of the hard tissues. In most of the cases, cervical tooth lesions are revealed to be more common as the age increases. Several studies have reported the difference in the prevalence of cervical abrasion between males and females. Many reports suggest that cervical abrasion is commonly associated with improper tooth brushing habits. To evaluate the prevalence of cervical abrasion between genders and its influence on age. It is a retrospective study conducted using the case records of Saveetha Dental College and Hospital, Chennai, India from June 2019 to March 2020. Data including the patient’s name, patient’s identification number (PID), age, gender and presence of cervical abrasion were retrieved from the patients’ case records. A total of 742 consecutive case records were retrieved and analysed. Cervical abrasion was observed in 371 individuals of this study. High prevalence of cervical abrasions was seen in males (70.9%) compared to females (29.1%). Most of the cases were observed in individuals within the 41-50 years age group (28.8%), and the least was seen within the 11-20 years age group (0.3%). Within the limits of the study, most of the cervical abrasion cases are recorded in individuals within the 41-50 years age group with higher predilection in males. There is a statistically significant association of cervical abrasion with age and gender.


2021 ◽  
Vol 27 ◽  
Author(s):  
Lilla Tamási ◽  
Krisztián Horváth ◽  
Zoltán Kiss ◽  
Krisztina Bogos ◽  
Gyula Ostoros ◽  
...  

Objective: No assessment was conducted describing the age and gender specific epidemiology of lung cancer (LC) prior to 2018 in Hungary, thus the objective of this study was to appraise the detailed epidemiology of lung cancer (ICD-10 C34) in Hungary based on a retrospective analysis of the National Health Insurance Fund database.Methods: This longitudinal study included patients aged ≥20 years with LC diagnosis (ICD-10 C34) between January 1, 2011 and December 31, 2016. Patients with different cancer-related codes 6 months before or 12 months after LC diagnosis or having any cancer treatment other than lung cancer protocols were excluded.Results: Lung cancer incidence and mortality increased with age, peaking in the 70–79 age group (375.0/100,000 person-years) among males, while at 60–69 age group for females (148.1/100,000 person-years). The male-to-female incidence rate ratio reached 2.46–3.01 (p &lt; 0.0001) among the 70–79 age group. We found 2–11% decrease in male incidence rate at most age groups, while a significant 1–3% increase was observed in older females (&gt;60) annually during the study period.Conclusion: This nationwide epidemiology study demonstrated that LC incidence and mortality in Hungary decreased in younger male and female population, however we found significant increase of incidence in older female population, similar to international trends. Incidence rates peaked in younger age-groups compared to Western countries, most likely due to higher smoking prevalence in these cohorts, while lower age LC incidence could be attributed to higher competing cardiovascular risk resulting in earlier mortality in smoking population.


Author(s):  
Mehmet Öztürk ◽  
Emine Uysal ◽  
Halil İbrahim Duran ◽  
Zuhal İnce Bayramoğlu ◽  
Abidin Kılınçer

Objective: To perform morphometric analysis of corpus callosum (CC) by using callosal area (CA), supratentorial-supracallosal area (SSA) and CA/SSA parameters in a healthy pediatric population and to investigate changes according to age and gender. Method: Method: This retrospective study included a total of 313 children (154 boys, 159 girls) aged between 3-17 years. The cases were divided into three groups according to age: 3-6 years (Group 1) (pre-school), 7-12 years (Group 2) (preadolescent) and 13-17 years (Group 3) (adolescent). CA and SSA were measured on the mid-sagittal plane on T1-weighted images. CA/ SSA index was calculated. Differences in age, CA, SSA, and ratio parameters among the gender groups were compared using the Mann-Whitney U or the t-test. Results: Median values of CA (p= 0.002), mean values of SSA (p=0.001) and CA/SSA ratios (p= 0.04) were significantly higher in boys compared to girls. The median CA and mean CA/SSA ratios in Group 3 were significantly higher than Groups 1 and 2 (p= 0.001). Mean CA/SSA ratio values of boys and girls in Age Group 3 were significantly higher than Group 1 (p= 0.001) and significantly higher than Age Group 2 in girls. There were highly significant positive correlations of age with CA (p=0.001, r=0.47), SSA (p=0.028, r=0.12) and CA/SSA ratio (p=0.001, r=042). There was a highly significant and positive correlation between CA and SSA (p=0.001, r=0.25) and CA/SSA ratio (p=0.001, r=0.87). Conclusion: CA, SSA, and CA/ SSA ratio values in children are affected by age and gender. These parameters can be used as reference values for the diagnosis of congenital and acquired pathologies affecting the corpus callosum.


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