scholarly journals Donor and tissue profiling at the time of eye donation at a tertiary care hospital in western India

Author(s):  
Devdatta J. Gohel ◽  
Atul Kamath M. ◽  
Dhananjay A. Bhosale ◽  
Binita N. Gadhavi

Background: The purpose of this study was to analyse the donor and tissue profiling of eyes donated at a tertiary care center in western India.Methods: Eye bank records were analysed for the period December 2014- December 2016. Variables studied included donor demographics (age, gender, ethnicity) cause of death of donor, consent for donation, whether the donation was voluntary or motivated, death to preservation interval, preservation to utilization interval, corneal suitability for transplantation and corneal tissue utilization.Results: During this study period, 200 corneal tissues were retrieved from 100 donors (male: female= 33: 17). The mean age of donors was 63 years (range: 18-91 years). Most common age group of donors belonged to 70-79 year age group. Most of the donors belonged to the class III of socio-economic status (35%). The most common cause of death was cardiorespiratory arrest (63%). Majority donors were voluntary (71%). Most consent for eye donation was given by sons (51%) or daughters (17%). Most of the donations were done at the deceased houses (64%). Mean death to preservation interval was 2.8 hours. Total corneas suitable for transplantation were 43% out of which 20% were utilised with the most common cause for disuse being septicaemia (23%) and poor quality of tissue (57%). Majority of patients had comorbidities with hypertension being most common (76%).Conclusions: With fairly less corneal tissue utilization, there is need for awareness among people in order to know the proper technique of preservation of eyes once death occurs and to increase motivational donations. 

2013 ◽  
Vol 2 (1) ◽  
pp. 10-13 ◽  
Author(s):  
Ajay Risal ◽  
Pushpa Prasad Sharma ◽  
Rajkumar Karki

Background and Aims- Self-poisoning is the commonest mode of suicide in our part of the world. Patients attempting suicide by self-poisoning usually land up in the Emergency. They are admitted for management of medical complications and subsequently referred to Psychiatry for evaluation of possible Psychiatric illnesses. The aim of this study was to explore the patterns of psychiatric illnesses in the patients admitted for self-poisoning in a tertiary care center in Nepal. Methods- The study population included those patients who were admitted and being managed for self-poisoning and brought for psychiatric evaluation during the period of one year (1st June 2011- 30th June 2012) at Dhulikhel Hospital, Nepal. Each patient underwent a detailed psychiatric evaluation by a consultant psychiatrist once they were medically stable. Details including sociodemographic data, psychiatric diagnosis, and treatment offered and outcome was tabulated and analyzed using SPSS-16. Results- Among the total patients (N=100), 43 were in the age group 21-40 years, median age being 27.5. There was almost equal gender distribution. Majority was of Mongolian ethnicity, homemaker by occupation and married. More than 90% were single-attempters, suicidal attempt using organophosphorus compounds. Almost 50% had depression; family dispute (19%) and marital disharmony (17%) were the most common psychosocial precipitant. Conclusion- Patients with history of self-poisoning are commonly brought to the Emergency Department of any tertiary care hospital. It is widely prevalent on younger age group. It is usually by the use of Organophosphorus compound in our setting and most commonly associated with depression. Hence, psychiatric care is essential for these patients. Journal of Advances in Internal Medicine 2013;02(01):10-13 DOI: http://dx.doi.org/10.3126/jaim.v2i1.7630


2021 ◽  
pp. 23-26
Author(s):  
Saurabh Shivprasad Kakani ◽  
Saurabh Padiya ◽  
Asmita Surywanshi ◽  
Ejaj Patel

Maxillofacial injuries account for a large group of patients in the emergency department in tertiary care hospital, presenting as an isolated injury or a part of poly trauma. Road trafc accidents are the commonest cause of maxillofacial injuries. Such injuries are clinically important as they cause facial disgurement and thus imposing emotional, morbidity and cosmetic dependence. To observe these fractures and decide appropriate management lines, there is a need for imaging aid. The main purpose of imaging guidance is to nd and characterize the fractures and associated injuries. Aim:Study of prole of multi detector computed tomography in maxillo-facial injury in a tertiary care centre. Materials and methods: The cases coming to the emergency department and then forwarded to department of Radiology, MGM medical college and hospital, Aurangabad for CT scan formed the source of the data and were studied in detail. Detailed history of the cases was taken. Written and informed consent were taken for undergoing CT scan examination. Patients were scanned using 16 slice Toshiba acquilion machine. The data was tabulated and observed and conclusions were made. Results: Total 175 number of patient were included in the study and CT scan for maxillo-facial injuries were conducted. Diagnosis of the maxillofacial injuries were done and the fractures were classied according to age, gender, location and its subsets. According to our study 21-30 years of age group was the most common age group to be involved in maxillo-facial injuries. Frequency of maxillo-facial injuries was found to be more in male than female. Maxillo facial injuries occurred mostly due to road trafc accidents. Orbit was seen as the most common bone to be fractured followed by fracture of maxilla bone. Orbital wall fracture happen to be overall most common bone affected amongst all the other facial bones.


Author(s):  
Shahul Hameed G. ◽  
Karthik Raja S.

<p class="abstract"><strong>Background:</strong> Skin diseases among the pediatric age group people are more common and it contributes to significant burden to health sectors. Also, the pattern of skin diseases changes consistently with reference to place and time. Hence the present study was conducted to assess the pattern of skin diseases in pediatric age group patients attending a tertiary care hospital.</p><p class="abstract"><strong>Methods:</strong> The cross-sectional study was conducted by the department of Dermatology, Venereology and Leprosy at Sri Muthukumaran Medical College Hospital and Research Institute, among the pediatric age group patients attending the outpatient department, during the month of October to December 2019. A total of 412 pediatric age group patients with skin disorder were included in the study. The study was conducted using a proforma with the clinical history and diagnosis of the participants. Data was entered in Microsoft excel and data analysis was done using SPSS version 17.<strong></strong></p><p class="abstract"><strong>Results:</strong> The common skin disorders reported in this study includes infections (34.7%) followed by dermatitis (32.3%), infestations (11.4%), miliaria (8.3%), popular urticaria (7.5%) and urticaria (6.1%). Among the infections fungal, bacterial and viral pathogens contributes to 16.3%, 10.9% and 7.5% of cases, respectively. Also 11.2% of cases were found to be infested with scabies (9.2%) and pediculosis (2.2%).</p><p class="abstract"><strong>Conclusions:</strong> Skin disorders in the pediatric age group are common and showing increasing trend. Hence health education of the parents and the school children about good nutrition, hygiene practices, and proper hydration of skin can be promoting in order to reduce the burden of skin disorders.</p>


2020 ◽  
Vol 58 (231) ◽  
Author(s):  
Sangita Thapa ◽  
Rabindra Jang Rayamajhi

Introduction: As the medical facilities are improving, the life expectancy is increasing which has led to rapid rise in elderly population. The epidemiology of many diseases in elderly has been modified, including calcium imbalance. This study aims to know the prevalence of hypocalcemia in elderly population visiting a tertiary care center of Kathmandu. Methods: A descriptive cross-sectional study was conducted in a tertiary care center of Kathmandu from March to July 2020 after obtaining ethical clearance (Ref: 2003202007). Total 402 participants at or above 60 years of age groups visiting outpatient departments were included in the study by convenience sampling method excluding those under vitamin D and calcium supplements. Serum total calcium level was measured using standard routine method and corrected with albumin. The serum calcium value less than 8 mg/dl was considered as hypocalcemia in accordance with the reference range of our laboratory. Data analysis for calculation of frequency and proportion was done in Statistical Package of Social Sciences. Results: The prevalence of hypocalcaemia in elderly was found to be 97 (24.1%). Out of 286 participants of age group 60-74 years, hypocalcemia was seen in 75 (26.2%) and among 116 participants of age group >74 years, 22 (19%) were hypocalcemic. Among 181 male participants, 44 (24.3%) had hypocalcemia and out of 221 female participants, 53 (24%) had hypocalcemia. Conclusions: The finding of present study suggests that hypocalcemia is common among elderly which can be life threatening. Therefore, regular monitoring of serum calcium is recommended for this age group.


2019 ◽  
Vol 6 (3) ◽  
pp. 989
Author(s):  
Chandra Mohan Chekkali ◽  
Rakesh Kotha ◽  
Himabindu Singh ◽  
Narahari Bapanpalli ◽  
Sadiqua Anjum ◽  
...  

Background: Following the invention of monaural stethoscope by Laennec and X ray by Roentgen in 18th century there was spectacular advancements in cardiology. The myocardium can be affected by various disease process unrelated to abnormal pressure or volume loads. These processes may be inflammatory, metabolic, infiltrative, ischemic or primary with significant overlap. These diseases usually present as cardiomegaly. In pediatric age group cardiac diseases will present early, sometimes without any signs and symptoms like sudden death due to less cardiac reserve. Few cases of sudden death also showed huge cardiomegaly in postmortem X rays. authors want to carry out this study to find out most common cause of cardiomegaly with silent chest as authors usually miss the diagnosis and these cases may present as sudden death without giving much time to intervene. The aim of the study is to know the most common cause of cardiomegaly without significant murmur in pediatric age group above one year.Methods: Prospective observational study done at a tertiary care hospital Hyderabad over a period of one year from January 2018 to January2019.Results: Most common cause of cardiomegaly without significant murmur was cardiac beriberi. It is mostly prevalent in rural areas of Telangana, mostly occurring in breastfed babies and below six years. All cases were recovered after proper treatment. Fortunately, it is associated with nil mortality, if timely treatment was initiated.Conclusions: Cardiac beriberi which is easily preventable and if treated in proper time it will associated with nil mortality. As it was occurring commonly breastfed babies supplementation of Thiamine to mothers was very useful as a preventive strategy.


2021 ◽  
pp. 11-13
Author(s):  
Somnath Choudhury ◽  
Jayanta Dutta ◽  
Ashis Majumdar

Damage to the cornea is the second most common cause of visual impairment and blindness which accounts for about 6–8 million of the total blind cases in the world. The majority of blinding corneal 1,2 damage in the form of trachoma affects 4.9 million individuals. Other major causes include ocular trauma, ulceration, xerophthalmia, ophthalmia neonatorum, onchocerciasis, leprosy, and use of traditional eye medicines


2021 ◽  
Vol 71 (3) ◽  
pp. 942-46
Author(s):  
Khurram Mansoor ◽  
Muhammad Osama ◽  
Muhammad Ishaque ◽  
Sohail Sabir ◽  
Hafeez Ud Din ◽  
...  

Objective: To evaluate outcome of diagnostic kidney biopsy in patients with renal allograft dysfunction at a tertiary care hospital. Study Design: Retrospective observational study. Place and Duration of Study: Armed Forces Institute of Urology, Rawalpindi, from Jan 2014 to Jan 2020. Methodology: A consolidate registry review was carried to formulate this study. The registry data exists at our center containing information about the graft dysfunction (manifesting as proteinuria, deranged urea and creatinine or urine sediment abnormalities) and other major indications which warrant probing with biopsy. The histopathological diagnosis of these biopsies is confirmed from the nephro-pathology registry before finalization of diagnosis. Results: A total of 94 diagnostic kidney biopsies were performed in patients with graft dysfunction. Out of 94 biopsies, 80 (85.1%) patients were male while 14 (14.9%) were female patients. The most frequent single cause for graft dysfunction was Cell Mediated Rejection (n 12, 24.5%) followed by Interstitial Fibrosis and Tubular Atrophy/Acute Tubular Injury. The most common cause among the glomerulonephritis was Membranoproliferative Glomerulonephritis (n 3, 6.1%) followed by others. The most common cause for mixed pathology remainedcell mediated rejection with Interstitial fibrosis and tubular atrophy (n 8, 17.8%). Conclusion: Cell mediated rejection is thecommonest pathology responsible for renal allograft dysfunction both as a single lesion as well as part of mixed pathology.


2020 ◽  
Vol 14 (3) ◽  
pp. 2047-2051
Author(s):  
Ravindra V. Shinde ◽  
Anjali R. Shinde ◽  
Anjali D. Patil ◽  
S.K. Pawar ◽  
S.T. Mohite ◽  
...  

Acute viral hepatitis(AVH) is caused by Hepatitis A (HAV) and Hepatitis E(HEV). It is major health burden in India. Both the viruses HAV and HEV are primarily transmitted via the faeco-oral course. Study was conducted to determine the seroprevalence of HAV, HEV and rate of co-infection in AVH patients attending rural tertiary care centre. A retrospective laboratory record based study was carried out in rural tertiary health care center located in Western Maharashtra. Laboratory and Medical records of suspected acute viral infection patients were analyzed during study. Study period was June 2014 to July 2018. Commercially available ELISA kits of IgM anti-HAV and IgM anti-HEV were used to analyze serum samples of suspected study participants. Tests were carried out as per the manufacturer’s instructions. A total of 778 acute viral hepatitis cases were included in the study from July 2014 to July 2018 among which 85/778 (10.9 %) detected positive for HAV and 121/778 (15.6%) detected positive for HEV. Co-infection was identified in 6/778(0.8 %). Jaundice, fever fatigue and hepatomegaly were common clinical presentation in HAV, HEV and confection with both viruses in acute viral hepatitis patients. Study indicated low exposure to HAV in childhood bellow 16 years. Co-infection rate was detected high in 16-25 years age group. Vaccination policy against HAV in adolescent age group needed as there is change epidemiological shift of HAV which has been observed in the current study. These data will helps for planning future vaccination strategies, better implementation sanitation program, and safe water supply in this geographic area.


2019 ◽  
pp. 1-2
Author(s):  
Meghna Kinjalk ◽  
Dilraj Kadlas* ◽  
Pooja Agarwal

The morbidity and quality of life after head injury is long and devastating.The symptoms may persist for lifetime and if not, then can be long enough to affect a person's health/the working conditions and definitely the monetary factor for coping up with this comes into a larger picture.It is also one of the leading causes of lifelong disability or death worldwide.The presentation may vary between a conscious patient on arrival to the emergency room to a person with seizures,ear bleed or drowsiness.The various types of presentation go hand in hand with different types of head injury, its management,prognosis and long-term impact on a person's life.Despite various studies and appropriate guidelines, the morbidity after head injury remains high.This study has a purpose to correlate various presentations of head injury, the epidemiology of head injury,types of head injury and its management options in a tertiary acre hospital. OBJECTIVES: a. To study the demographic profile and gender distribution of patients presenting to emergency room in a tertiary care hospital in western India. b. To study the mode and type of head injury,Imaging finding and its management. METHODOLOGY: It was a prospective study of consecutive 200 patients presenting to a tertiary care hospital: Mahatma Gandhi Mission's Medical college and hospital,Kamothe,Navi Mumbai.Institute Ethical committee approval was obtained before the start of study. All the age group was included. There were no exclusion criteria. Result was tabulated and analysed at the end of the study. RESULT:This study enrolled 200 patients in which male were more common than female,young adults more commonly affected.Majority of patients were treated conservatively and improved. CONCLUSION: The most common cause of traumatic brain injury is road traffic accident and relating it with the most common age group ,brings us to the conclusion of importance of safety measures on road amongst young adults.Hence , preventing the wrath of morbidity associated with the debilitating head injury.This also helps in improving the quality of life of the patient and the care giver


Sign in / Sign up

Export Citation Format

Share Document