scholarly journals Seroprevalensi dan Faktor Risiko Rabies pada Anjing di Daerah Endemis Kabupaten Sukabumi

2021 ◽  
Vol 26 (3) ◽  
pp. 436-443
Author(s):  
Ardilasunu Wicaksono ◽  
Abdul Zahid ◽  
Etih Sudarnika ◽  
Dordia Anindita Rotinsulu ◽  
Denny Widaya Lukman ◽  
...  

Sukabumi District is reported to date as an endemic rabies area in West Java Province. In supporting the rabies control programs, the occurrence of rabies needs to be determined to decrease the number of cases. This research aims to determine the seroprevalence of rabies and identify the risk factors associated with rabies in the district. The research was conducted in Jampang Tengah and Cisolok sub-districts with positive rabies cases on dogs and humans. The blood samples were taken from 191 selected dogs using simple random sampling. Rabies antibody titer was measured using ELISA, and the risk factor was identified using selected dogs’ data classified into intrinsic and extrinsic characteristics. Data were analyzed using the chi-square test and the calculation of the odds ratio. The results showed that the seroprevalence of rabies was 7.9% (4.9-10.9%). The average antibody titer was 0.23 EU with a minimum value of 0.03 EU and a maximum of 0.96 EU. Thus, as high as 7.8% of the population showed rabies seropositivity from the unvaccinated dogs, while among the vaccinated dogs, only 8.0% of the population with rabies protective antibody titer. The significant risk factor of rabies seroprevalence is the typology of raising area (p = 0.003), revealing that the dogs raised in the coastal area had the odds of 5.8 (1.6-21.2) higher to get the rabies seropositivity than the dogs raised in the highland area.   Keywords: antibody titre, dogs, rabies, risk factor, seroprevalence

2016 ◽  
Vol 56 (4) ◽  
pp. 226
Author(s):  
Yuni Purwanti ◽  
Sutaryo Sutaryo ◽  
Sri Mulatsih ◽  
Pungky Ardani Kusuma

Background Wilms tumor is the most common renal malignancy in children (95%) and one of the leading causes of death in children, with high mortality rates in developing countries. Identifying risk factors for mortality is important in order to provide early intervention to improve cure rates.Objective To identify risk factors for mortality in children with Wilms tumor.Methods We performed a case-control study of children (0-18 years of age) with Wilms tumor admitted to Dr. Sardjito Hospital between 2005 and 2012. The case group consisted of children who died of Wilms tumor, whereas the control group were children who survived. Data were collected from medical records. Statistical analyses using Chi-square and logistic regression tests were done to determine odds ratios and 95% CI of the potential risk factors for mortality from Wilms tumor.Results Thirty-five children with Wilms tumor were admitted to Dr. Sardjito Hospital during the study period. Nine (26%) children died and 26 survived. Stage ≥III was a significant risk factor for mortality in chidren with Wilms tumor (OR 62.8; 95%CI 5.6 to 70.5). Age ≥2 years (OR 1.4; 95%CI 0.1 to 14.3) and male sex (OR 1.2; 95%CI 0.1 to 10.8) were not significant risk factors for mortality.Conclusion Stage ≥III is a risk factor for mortality in children with Wilms tumor. 


2013 ◽  
Vol 131 (1) ◽  
pp. 27-34 ◽  
Author(s):  
Orlando Milhomem Mota ◽  
Maria Paula Curado ◽  
José Carlos Oliveira ◽  
Edesio Martins ◽  
Daniela Medeiros Milhomem Cardoso

CONTEXT AND OBJECTIVESEsophageal cancer is the eighth commonest type of cancer worldwide, occupying sixth place in terms of mortality. Smoking and alcohol use are known risk factors for this type of cancer. The aim here was to evaluate the risk factors for esophageal cancer in a low-incidence area.DESIGN AND SETTINGCase-control study in Goiânia, with 99 cases of esophageal cancer and 223 controls.METHODSThe variables were sociodemographic, dietary, occupational and lifestyle data. The sample was analyzed using the chi-square test, Mann-Whitney test and Mantel-Haenszel approach for multivariate analysis. Odds ratios (OR) were calculated with 5% significance and 95% confidence intervals.RESULTSThe risk of esophageal cancer was higher in patients ≥ 55 years (OR = 1.95; P < 0.001). Patients from rural areas were at greater risk of esophageal cancer (OR = 4.9; P < 0.001). Smoking was a risk factor among the cases (OR = 3.8; P < 0.001), as was exposure to woodstoves (OR = 4.42; P < 0.001). The practice of oral sex was not a risk factor (OR = 0.45; P = 0.04). Consumption of apples, pears, vegetables, cruciferous vegetables and fruit juices were protective against esophageal cancer.CONCLUSIONIn a region in which the incidence of esophageal cancer is low, the most significant risk factors were exposure to woodstoves, smoking and living in rural areas.


2019 ◽  
Vol 34 (5) ◽  
pp. 766-766
Author(s):  
S Jennings ◽  
J French ◽  
C Holland ◽  
M Collins ◽  
A P Kontos

Abstract Purpose The objective of this study was to examine differences in self-reported symptoms, neurocognitive performance, and vestibular-ocular insufficiencies between patients’ first and second concussions. A secondary purpose was to explore the role of risk factors on recovery. Methods We conducted a retrospective medical chart review of 73 (32-M/41-F) patients aged 15.69 (SD=1.67) years from a concussion specialty clinic with two separate concussions (84.9% of 1st and 79.5% of 2nd sport-related) that occurred between August 2010 and April 2018. Clinical outcomes included the PCSS, ImPACT, and the Vestibular/Ocular Motor Screening (VOMS). A series of paired samples t-tests were used to compare clinical outcomes along with chi-square analyses for risk factor associations. Results Verbal memory scores were higher following the second (M=80.67, SD=15.3) (M=76.32, SD=15.65) (t[73]=–2.18, p=.03) concussion. Visual motor processing speed was faster following the second concussion (M=35.04, SD= 7.90) (M=31.35, SD=7.63) (t[73]=–5.72, p<.001). There were no other significant differences observed. Recovery time was similar for the first (61.07, SD=58.41.5) and second (67.91 SD=70.10) respectively, t(70)=–.91, p=.37. There was no relationship between any risk factors, and recovery time for either injury with the exception a significant association between gender and recovery time (>21 days) with the 1st injury for females (χ2, N=73)=10.58, p=.001. Conclusion Findings suggest that a second concussion does not result in more pronounced symptoms, worse neurocognitive performance, or increased deficits on vestibular/ocular performance and/or longer recovery time. The only significant risk factor to a recovery over 21 days included gender.


2018 ◽  
Vol 58 (5) ◽  
pp. 238-41 ◽  
Author(s):  
Husein Albar ◽  
Fadel Bilondatu ◽  
Dasril Daud

Background Nephrotic syndrome (NS) is the most common kidney disease in children and is characterized by edema, massive proteinuria, hypoalbuminemia, and hyperlipidemia. High relapse rate remains a major problem in the management of this syndrome. Objective To identify risk factors for relapse in pediatric nephrotic syndrome. Methods This study was carried out in the Wahidin Sudirohusodo Teaching Hospital in Makassar, South Sulawesi, Indonesia, from January to August 2017 using complete medical records of children diagnosed with NS. Subjects were divided into 2 groups: 1) relapsed NS or 2) non-relapsed NS.  The following potential risk factors for relapse were analyzed using Chi-square test: age, sex, nutritional status, hypertension, serum creatinine level, and infection at the time of established diagnosis of NS. Results A total of 142 children with NS who fulfilled the inclusion criteria aged 1.4 to 17.5 years were included in the study. Subjects were mostly boys (66.2%), with a male: female ratio of 1.95:1. The relapsed NS group had 80 cases (56.3%) and the non-relapsed NS group had 62 cases (43.7%). Statistical analysis revealed that nutritional status was a significant risk factor for relapse in pediatric nephrotic syndrome (P<0.05). Conclusion Nutritional status is an independent risk factor for relapse in pediatric nephrotic syndrome. 


2017 ◽  
Vol 5 (2) ◽  
pp. 142
Author(s):  
Ajeng Nindya Cahyaningrum

Dental caries disease is mostly found on toddlers age 3-5. Mothers hopefully, can do precaution by maintaining toddlers dental and mouth health properly. The purpose of this research is to analyze the relationship between the knowledge, attitude, and action of the mother about dental and mouth health against dental caries. This study used case control design. The subjects were taken from a population by simple random sampling technique. Analysis of the results of studies using non-parametric test is Chi-square test, The result showed mothers’ knowledge of oral health into the category of low at 57.4%, with a risk factor (OR) gained 4.04 times higher dental caries, while most of the low attitude about oral health toddlers of 62.5%, with a risk factor (OR) gained 3,33 times higher dental caries, while the majority of the capital actions included in the unfavorable category that is 58.8%, with the risk factors (OR) gained 4.00 times higher dental caries. The analysis results are obtained the relationship between knowledge, attitudes, and actions of the mother’s oral health on the incidence of dental caries toddlers. It is suggested the parents, especially the mother has an important role for the growth of children, let increased knowledge about oral health toddlers that includes understanding, benefits, and the prevention of diseases that can be prevented by maintaining healthy teeth and mouth. Keywords:knowledge, practices, dental caries, mother, toddler


2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
Line Heylen ◽  
Margaretha Van Kerrebroeck ◽  
Els Oris ◽  
Liesbet Hendrickx ◽  
Eline Macken ◽  
...  

Abstract Background and Aims Hemodialysis patients face an exceptional risk in the current COVID19 pandemic, both for infection/transmission as well as for mortality. All efforts to reduce potential risk factors are needed to protect this vulnerable group. We aimed to evaluate risk factors for SARS-CoV-2 infection and transmission during the first COVID19 wave, in order to tackle these factors in the second. Method We included all hemodialysis patients who were dialyzed at our central institution on March 19, 2020 (date of first COVID19 diagnosis). External low care and home hemodialysis patients were excluded. Our central hemodialysis center has 5 dialysis shifts in 6 units located next to each other, with a separate seventh dialysis unit dedicated for COVID19 isolation. COVID19 infections were diagnosed with nasopharyngeal swab PCR at the discretion of the treating nephrologist. On May 18 and 19, after the first wave, all hemodialysis patients were evaluated for presence of SARS-CoV-2 antibodies using ELISA to screen for previous asymptomatic infections. Chi square and logistic regression were used for statistical analyses. Results 216 hemodialysis patients were included in this study, with a mean age of 72 years old (IQR 65-83). COVID19 was diagnosed in 17 patients during the first wave: in 15 symptomatic cases through nasopharyngeal swab PCR and in two additional asymptomatic cases through SARS-CoV-2 IgG positivity. Interestingly, we observed that 58.8% of COVID19 patients were transported by the same transport company, while this company transports only 20.4% of hemodialysis patients (p=0.005) (Figure A). As such, 22.7% of patients transported by this company became infected (OR 6.93, 95% CI 2.49-20.34, p=0.0002). Conclusion Institutional transport was the most significant risk factor for SARS-CoV-2 infection among hemodialysis patients at our center. After stringent prevention measures we were able to prevent transmission during transport in the second wave of the COVID19 pandemic.


e-CliniC ◽  
2013 ◽  
Vol 1 (1) ◽  
Author(s):  
Lilis Pratiwi ◽  
Eddy Suparman ◽  
Freddy Wagey

Abstract: Age is the most significant risk factor for the development of myoma uteri. The issue of myoma uteri in women's reproductive health continues to increase. The high incidence of myoma uteri between the ages of 35-50 years shows an association of myoma uteri with estrogen. This study aimed to determine the relationship between the incidence of myoma uteri during this stage in the RSUP Prof. Dr. R.D. Manado Kandou from March until October 2012. This study was a retrospective observational descriptive analytic cross-sectional approach. This was carried out by using the Chi Square. A 95% confidence level (α ≤ 0.05) and P ≤ 0.05 showed there was a relationship between the independent variables and dependent variables. Based on 353 cases of all diseases in the Obstetrics-Gynecology section between the ages of 18-49 years, those who suffered from myoma uteri were 108 cases. Those aged between 34-49 years (101 cases, 93.5%), suffered most from of myoma uteri while those aged between 18-33 were only 7 cases (6.5%). The Pearson Chi-Square test value was 43.394 and obtained P = 0.000. These results indicated there was a very significant correlation between the incidence of reproductive ages with myoma uteri (P = 0.000; α = 0.01). Conclusion: the high incidences of myoma uteri during reproductive ages showed no association with estrogen myoma uteri. Keywords: reproductive age, myoma uteri. Abstrak: Usia merupakan faktor risiko yang paling bermakna untuk perkembangan mioma uteri. Salah satu masalah kesehatan reproduksi wanita ialah mioma uteri dengan insidensi yang terus meningkat. Tingginya kejadian mioma uteri antara usia 35-50 tahun menunjukkan adanya hubungan mioma uteri dengan estrogen pada usia reproduksi. Penelitian ini bertujuan untuk mengetahui hubungan usia reproduksi dengan kejadian mioma uteri di RSUP Prof. Dr. R. D. Kandou Manado periode Maret sampai dengan Oktober 2012. Penelitian ini bersifat observasi analitik deskriptif retrospektif dengan cross sectional design. Uji statistik menggunakan Chi square test. Dengan tingkat kepercayaan 95% (α ≤ 0,05), jika P ≤ 0,05 maka terdapat hubungan antara variabel bebas dan variabel terikat. Dari 353 kasus untuk semua penyakit ginekologi di Bagian Obstetri-Ginekologi yang berusia antara18-49 tahun, terdapat 108 kasus dengan mioma uteri. Usia 34-49 tahun merupakan kasus terbanyak dengan mioma uteri yaitu 101 kasus (93,5%); dan yang berusia 18-33 tahun terdapat tujuh kasus (6,5%). Uji Pearson Chi-Square memperlihatkan nilai 43,394 dengan P = 0,000. Hasil ini menunjukkan terdapat hubungan yang sangat bermakna antara usia reproduksi dengan kejadian mioma uteri (P = 0,000; α = 0,01). Simpulan: Dari hasil penelitian di Bagian Obstetri-Ginekologi RSUP Prof. Dr. R.D. Kandou Manado periode 1 Maret - 31 Oktober 2012 diperoleh bahwa kasus ginekologi terbanyak pada pasien berusia 18-49 tahun ialah mioma uteri, dengan usia tersering 34-49 tahun. Kata kunci: usia reproduksi, mioma uteri.


e-CliniC ◽  
2013 ◽  
Vol 1 (1) ◽  
Author(s):  
Lilis Pratiwi

Abstract: Age is the most significant risk factor for the development of myoma uteri. The issue of myoma uteri in women's reproductive health continues to increase. The high incidence of myoma uteri between the ages of 35-50 years shows an association of myoma uteri with estrogen. This study aimed to determine the relationship between the incidence of myoma uteri during this stage in the RSUP Prof. Dr. R.D. Manado Kandou from March until October 2012. This study was a retrospective observational descriptive analytic cross-sectional approach. This was carried out by using the Chi Square. A 95% confidence level (α ≤ 0.05) and P ≤ 0.05 showed there was a relationship between the independent variables and dependent variables. Based on 353 cases of all diseases in the Obstetrics-Gynecology section between the ages of 18-49 years, those who suffered from myoma uteri were 108 cases. Those aged between 34-49 years (101 cases, 93.5%), suffered most from of myoma uteri while those aged between 18-33 were only 7 cases (6.5%). The Pearson Chi-Square test value was 43.394 and obtained P = 0.000. These results indicated there was a very significant correlation between the incidence of reproductive ages with myoma uteri (P = 0.000; α = 0.01). Conclusion: the high incidences of myoma uteri during reproductive ages showed no association with estrogen myoma uteri.Keywords: reproductive age, myoma uteri.Abstrak: Usia merupakan faktor risiko yang paling bermakna untuk perkembangan mioma uteri. Salah satu masalah kesehatan reproduksi wanita ialah mioma uteri dengan insidensi yang terus meningkat. Tingginya kejadian mioma uteri antara usia 35-50 tahun menunjukkan adanya hubungan mioma uteri dengan estrogen pada usia reproduksi. Penelitian ini bertujuan untuk mengetahui hubungan usia reproduksi dengan kejadian mioma uteri di RSUP Prof. Dr. R. D. Kandou Manado periode Maret sampai dengan Oktober 2012. Penelitian ini bersifat observasi analitik deskriptif retrospektif dengan cross sectional design. Uji statistik menggunakan Chi square test. Dengan tingkat kepercayaan 95% (α ≤ 0,05), jika P ≤ 0,05 maka terdapat hubungan antara variabel bebas dan variabel terikat. Dari 353 kasus untuk semua penyakit ginekologi di Bagian Obstetri-Ginekologi yang berusia antara18-49 tahun, terdapat 108 kasus dengan mioma uteri. Usia 34-49 tahun merupakan kasus terbanyak dengan mioma uteri yaitu 101 kasus (93,5%); dan yang berusia 18-33 tahun terdapat tujuh kasus (6,5%). Uji Pearson Chi-Square memperlihatkan nilai 43,394 dengan P = 0,000. Hasil ini menunjukkan terdapat hubungan yang sangat bermakna antara usia reproduksi dengan kejadian mioma uteri (P = 0,000; α = 0,01). Simpulan: Dari hasil penelitian di Bagian Obstetri-Ginekologi RSUP Prof. Dr. R.D. Kandou Manado periode 1 Maret - 31 Oktober 2012 diperoleh bahwa kasus ginekologi terbanyak pada pasien berusia 18-49 tahun ialah mioma uteri, dengan usia tersering 34-49 tahun.Kata kunci: usia reproduksi, mioma uteri.


2019 ◽  
Author(s):  
Shen Runnan ◽  
Zhou Xuezhen ◽  
Lin Xi ◽  
Qu Yingying ◽  
Mo Chunling ◽  
...  

Abstract Background: Catheter-related thrombosis (CRT) may lead to catheter infections and failure, further deep venous thrombosis (DVT), and pulmonary embolism (PE). Recognizing the risk factors for CRT is extremely important to inform the development of catheter-nursing guidelines.Methods: Data were collected from a total of 1532 patients who had undergone venous catheterization, including indwelling catheterization from March 19 to March 30, 2019 in Sun Yat-sen Memorial Hospital. The factors for which data were to be collected included the patients’ physical characteristics, catheter-associated factors, and factors associated with catheter nursing. Logistic regression analysis, the chi-square test, Fisher’s exact test, and the t-test were used to analyze the data. Results: Of the 1532 patients studied, 28 developed intraductal thrombi, and of the factors analyzed, tumor, a catheterization history, a history of thrombophilia, surgery during the week before catheterization, the catheterization duration were significant risk factors associated with CRT (all P < 0.05). There were no significant associations between the catheter brand, the number of lumens, the insertion direction, or the factors associated with catheter nursing and CRT (all P > 0.05). Anticoagulation therapy significantly decreases the risk of CRT ( P < 0.05 ). Conclusion: Tumor, a history of thrombophilia, a history of catheterization, surgery during the week before catheterization, and catheterization duration were associated with increased risks of CRT. Prophylactic anticoagulation is effective for preventing and treating CRT. Our study incorporates clear and systematic risk factors associated with CRT. The results are different from those of previous studies.


Crisis ◽  
2014 ◽  
Vol 35 (5) ◽  
pp. 330-337 ◽  
Author(s):  
Cun-Xian Jia ◽  
Lin-Lin Wang ◽  
Ai-Qiang Xu ◽  
Ai-Ying Dai ◽  
Ping Qin

Background: Physical illness is linked with an increased risk of suicide; however, evidence from China is limited. Aims: To assess the influence of physical illness on risk of suicide among rural residents of China, and to examine the differences in the characteristics of people completing suicide with physical illness from those without physical illness. Method: In all, 200 suicide cases and 200 control subjects, 1:1 pair-matched on sex and age, were included from 25 townships of three randomly selected counties in Shandong Province, China. One informant for each suicide or control subject was interviewed to collect data on the physical health condition and psychological and sociodemographic status. Results: The prevalence of physical illness in suicide cases (63.0%) was significantly higher than that in paired controls (41.0%; χ2 = 19.39, p < .001). Compared with suicide cases without physical illness, people who were physically ill and completed suicide were generally older, less educated, had lower family income, and reported a mental disorder less often. Physical illness denoted a significant risk factor for suicide with an associated odds ratio of 3.23 (95% CI: 1.85–5.62) after adjusted for important covariates. The elevated risk of suicide increased progressively with the number of comorbid illnesses. Cancer, stroke, and a group of illnesses comprising dementia, hemiplegia, and encephalatrophy had a particularly strong effect among the commonly reported diagnoses in this study population. Conclusion: Physical illness is an important risk factor for suicide in rural residents of China. Efforts for suicide prevention are needed and should be integrated with national strategies of health care in rural China.


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