scholarly journals A retrospective analysis of risk factors associated with catheter-related thrombosis: a single-center study

2019 ◽  
Author(s):  
Shen Runnan ◽  
Zhou Xuezhen ◽  
Lin Xi ◽  
Qu Yingying ◽  
Mo Chunling ◽  
...  

Abstract Background: Catheter-related thrombosis (CRT) may lead to catheter infections and failure, further deep venous thrombosis (DVT), and pulmonary embolism (PE). Recognizing the risk factors for CRT is extremely important to inform the development of catheter-nursing guidelines.Methods: Data were collected from a total of 1532 patients who had undergone venous catheterization, including indwelling catheterization from March 19 to March 30, 2019 in Sun Yat-sen Memorial Hospital. The factors for which data were to be collected included the patients’ physical characteristics, catheter-associated factors, and factors associated with catheter nursing. Logistic regression analysis, the chi-square test, Fisher’s exact test, and the t-test were used to analyze the data. Results: Of the 1532 patients studied, 28 developed intraductal thrombi, and of the factors analyzed, tumor, a catheterization history, a history of thrombophilia, surgery during the week before catheterization, the catheterization duration were significant risk factors associated with CRT (all P < 0.05). There were no significant associations between the catheter brand, the number of lumens, the insertion direction, or the factors associated with catheter nursing and CRT (all P > 0.05). Anticoagulation therapy significantly decreases the risk of CRT ( P < 0.05 ). Conclusion: Tumor, a history of thrombophilia, a history of catheterization, surgery during the week before catheterization, and catheterization duration were associated with increased risks of CRT. Prophylactic anticoagulation is effective for preventing and treating CRT. Our study incorporates clear and systematic risk factors associated with CRT. The results are different from those of previous studies.

Perfusion ◽  
2020 ◽  
Vol 35 (8) ◽  
pp. 806-813
Author(s):  
Xuezhen Zhou ◽  
Xi Lin ◽  
Runnan Shen ◽  
Yingying Qu ◽  
Chunling Mo ◽  
...  

Background: Catheter-related thrombosis may lead to catheter infections and failure, further deep venous thrombosis, and pulmonary embolism. Recognizing the risk factors for catheter-related thrombosis is extremely important to inform the development of catheter care guidelines. Methods: Data were collected from a total of 1,532 patients who had undergone venous catheterization, including indwelling catheterization from 19 March 2019 to 30 March 2019 in the Sun Yat-sen Memorial Hospital. The factors for which data were to be collected included the patients’ physical characteristics, catheter-related factors, and catheter care-related factors. Logistic regression analysis, the chi-squared test, Fisher’s exact test, and the t-test were used to analyze the data. Results: Of the 1,532 patients studied, 28 developed intraductal thrombi, and of the factors analyzed, malignancy, a catheterization history, a history of thrombophilia, surgery during the week before catheterization, the catheterization duration, and anticoagulant therapy were significant risk factors associated with catheter-related thrombosis (all p < 0.05). There were no significant associations between the catheter brand, the number of lumens, the insertion direction, or the factors associated with catheter care and catheter-related thrombosis (all p > 0.05). Conclusion: Our study incorporated clear and systematic risk factors associated with catheter-related thrombosis. Malignancy, history of thrombophilia, history of catheterization, surgery during the week before catheterization, and catheterization duration were associated with increased risks of catheter-related thrombosis. Prophylactic anticoagulation was effective for preventing and treating catheter-related thrombosis.


2021 ◽  
Vol 5 (3) ◽  
pp. 307
Author(s):  
Riani Widia Parantika ◽  
Gatut Hardianto ◽  
Muhammad Miftahussurur ◽  
Wahyul Anis

Background: Preeclampsia can threaten the health of the mother and fetus during pregnancy and childbirth, besides that it also increases the risk of long-term complications and has the potential to cause death. The incidence of preeclampsia at the RSUD Engku Haji Daud Tanjung Uban showed an increase in the last three years, namely the occurrence from 2017 as many as 23 cases to 56 cases in 2019. The condition of preeclampsia can worsen quickly and without warning, for that, it must be detected and managed appropriately. This study aimed to identify the association of obesity, multiple pregnancies, and previous history of preeclampsia with the incidence of preeclampsia in maternity women. Methods: This study uses a case-control study design. Performed on women giving birth in the period January – December 2019, consisting of 56 cases and 112 controls. Maternal women with preeclampsia were cases and women who were not diagnosed with preeclampsia were controls. The data was obtained from the respondents' medical records, then analyzed using the Chi-Square test or Fisher's Exact test with a value of = 0,05. Results: Obesity was associated with an increased risk of preeclampsia (OR= 4,746, 95% CI 2,381-9,460; P=0,000). Multiple pregnancies were associated with a significantly increased risk of preeclampsia (OR=15,857, 95% CI 1,899-132,384; P=0,002). Likewise, a previous history of preeclampsia was associated with a markedly increased risk of preeclampsia (OR=99,000, 95% CI 22,057-444,343; P=0,000). Conclusion: Based on these data, it was found that obesity, multiple pregnancies, and previous history of preeclampsia were significant risk factors for the occurrence of preeclampsia. It is important to identify risk factors for preeclampsia early, so that appropriate management can be carried out, to prevent complications.


Author(s):  
Yudiarsi Eppang

The aim of the study: To determine the risk factors associated with the incidence of placenta previa in mothers who gave birth at RSUD Daya Makassar City. Method: Quantitative Research, with a cross sectional approach. The design of this study was used with the goal to knowing the risk factors associated with the incidence of placenta previa in mothers who gave birth at RSUD Daya Kota Makassar in 2020. The population in this study were all mothers who experienced placenta previa recorded as data in the INC room at RSUD. Daya City of Makassar in 2020. The sample in this study were women who experienced placenta previa recorded in the INC room data at RSUD Daya Kota Makassar in 2020. Results: This study shows that 15 respondents studied showed that there was a relationship between age, parity, history of curettage, and the distance between pregnancies to the incidence of placenta previa. Based on the results of the chi square test, the results obtained were age (p = 0.019), parity (p = 0.005), history of curettage (p = 0.020) and pregnancy distance (p = 0.020). Conclusion: in this study there is a significant relationship between age, parity, history of curettage, and the distance between pregnancies to the incidence of placenta previa at RSUD Daya Kota Makassar. Suggestion: Suggestions for health workers need to increase antenatal supervision of pregnant women who have a history of obstetrics, so that risky pregnant women can be managed properly


1993 ◽  
Vol 70 (03) ◽  
pp. 393-396 ◽  
Author(s):  
Mandeep S Dhami ◽  
Robert D Bona ◽  
John A Calogero ◽  
Richard M Hellman

SummaryA retrospective study was done to determine the incidence of and the risk factors predisposing to clinical venous thromboembolism (VTE) in patients treated for high grade gliomas. Medical records of 68 consecutive patients diagnosed and treated at Saint Francis Hospital and Medical Center from January 1986 to June 1991 were reviewed. The follow up was to time of death or at least 6 months (up to December 1991). All clinically suspected episodes of VTE were confirmed by objective tests. Sixteen episodes of VTE were detected in 13 patients for an overall episode rate of 23.5%. Administration of chemotherapy (p = 0.027, two tailed Fisher exact test) and presence of paresis (p = 0.031, two tailed Fisher exact test) were statistically significant risk factors for the development of VTE. Thrombotic events were more likely to occur in the paretic limb and this difference was statistically significant (p = 0.00049, chi square test, with Yates correction). No major bleeding complications were seen in the nine episodes treated with long term anticoagulation.We conclude that venous thromboembolic complications are frequently encountered in patients being treated for high grade gliomas and the presence of paresis and the administration of chemotherapy increases the risk of such complications.


2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
Olaolu T. Olufemi ◽  
Danjuma B. Dantala ◽  
Paul A. Shinggu ◽  
Umesi A. Dike ◽  
Gbeminiyi R. Otolorin ◽  
...  

A cross-sectional study was conducted in Wukari, Taraba state, Nigeria, to determine the prevalence of Brucella antibodies and the risk factors associated with brucellosis in indigenous breeds of goats. A total of 386 goats were sampled from three political wards: Puje, Avyi, and Hospital: harvested sera samples were subjected to Rose Bengal Plate Test (RBPT). GraphPad Prism version 7.03 for Windows (GraphPad Software, La Jolla California, USA) was used to analyse the association between seroprevalence of brucellosis and age, sex, breed, location, and management system by using Chi square and Fisher’s exact test as appropriate. Brucellosis was detected in all three wards: Puje; 15%, Avyi; 6.6%, and Hospital; 7.6%. A prevalence rate of 2.8%, 8%, 18.7%, and 1% was recorded for <20-month, 22-35-month, 36-45-month, and ≥46-55-month age categories, respectively (P < 0.05). Only 9.5% was observed for male animals while 9.8% was observed for female animals with no statistical difference between the males and females. Breed-specific seroprevalence yielded 7.4%, 5.4% 12%, 12.8%, and 11.6%, for Cross, West Africa Dwarf, Red Sokoto, Kano Brown, and Sahel breeds of goat, respectively. There is an evidence of brucellosis (9.6%) in Wukari L.G.A, Taraba State, and age is a risk factor for the disease in the study area. There is a need to enlighten the public on the zoonotic potentials and economic impacts of brucellosis.


2013 ◽  
Vol 131 (1) ◽  
pp. 27-34 ◽  
Author(s):  
Orlando Milhomem Mota ◽  
Maria Paula Curado ◽  
José Carlos Oliveira ◽  
Edesio Martins ◽  
Daniela Medeiros Milhomem Cardoso

CONTEXT AND OBJECTIVESEsophageal cancer is the eighth commonest type of cancer worldwide, occupying sixth place in terms of mortality. Smoking and alcohol use are known risk factors for this type of cancer. The aim here was to evaluate the risk factors for esophageal cancer in a low-incidence area.DESIGN AND SETTINGCase-control study in Goiânia, with 99 cases of esophageal cancer and 223 controls.METHODSThe variables were sociodemographic, dietary, occupational and lifestyle data. The sample was analyzed using the chi-square test, Mann-Whitney test and Mantel-Haenszel approach for multivariate analysis. Odds ratios (OR) were calculated with 5% significance and 95% confidence intervals.RESULTSThe risk of esophageal cancer was higher in patients ≥ 55 years (OR = 1.95; P < 0.001). Patients from rural areas were at greater risk of esophageal cancer (OR = 4.9; P < 0.001). Smoking was a risk factor among the cases (OR = 3.8; P < 0.001), as was exposure to woodstoves (OR = 4.42; P < 0.001). The practice of oral sex was not a risk factor (OR = 0.45; P = 0.04). Consumption of apples, pears, vegetables, cruciferous vegetables and fruit juices were protective against esophageal cancer.CONCLUSIONIn a region in which the incidence of esophageal cancer is low, the most significant risk factors were exposure to woodstoves, smoking and living in rural areas.


2021 ◽  
Vol 15 (6) ◽  
pp. 267-276 ◽  
Author(s):  
Chayamon Suwansumrit ◽  
Worawan Jittham

Abstract Background Congenital heart diseases (CHDs) are the most common types of birth defects and contribute to a large proportion of infant morbidities and mortalities worldwide. These defects may require multiple surgical interventions impacting the infant's quality of life. Objectives To identify risk factors associated with CHD in a population of Thai children. Methods We conducted a case–control study of patients attending the Pediatric Clinic, Naresuan University Hospital, Thailand. We included data from pediatric patients diagnosed with CHDs as cases, and patients without cardiovascular abnormalities as controls. Risk data were collected from July 2019 to April 2020 using face-to-face interviews. Multiple logistic regression was used to analyze parental factors associated with CHDs. Results We included 249 cases classified into 2 groups according to severity and 304 patients as controls. For those less-severely affected (155 patients, 62.2%), ventricular septal defect (27.7%) was the most prevalent, whereas for those with severe CHDs, tetralogy of Fallot was the most prevalent (14.0%). There was no difference in sex distribution or maternal obstetric history between the groups. In multivariable analysis, a family history of CHDs (adjusted odds ratio [AOR] 4.67, 95% confidence interval (CI) 1.61–13.57, P = 0.005) and maternal exposure to second-hand cigarette smoke (AOR 1.58, 95% CI 1.03–2.42, P = 0.002) were identified as significant risk factors for CHDs. Conclusion A family history of CHDs and maternal exposure to second-hand cigarette smoke are associated with having offspring with CHDs in the population studied. These findings help us to encourage affected parents to obtain a fetal echocardiogram.


Author(s):  
Ika Avrilina Haryono ◽  
Adriana Palimbo ◽  
Difa Okti Al Kautsar

ABSTRAKLatar Belakang : Kanker payudara merupakan salah satu penyebab kematian utama pada wanita di dunia. Sejauh ini, kanker payudara paling sering diderita oleh wanita dengan perkiraan 43,3% juta kasus kanker baru yang didiagnosis pada tahun 2012. Angka kejadian kanker payudara bervariasi secara global dimana terjadi peningkatan insiden di negara berkembang tetapi cenderung menurun dinegara maju, dengan kasus pada negara berkembang (883.000 kasus) negara maju (794.000 kasus). Tujuan: Menganalisis faktor resiko yang berhubungan dengan kejadian kanker payudara meliputi faktor umur, umur pertama menstruasi, menopause, umur pertama kali menikah, riwayat penggunaan kontrasepsi hormonal, riwayat pemberian ASI, da riwayat kanker payudara pada keluarga.Metode: Penelitian ini adalah penelitian kuantitatif menggunakan metode survey analitik dengan rancangan cross sectional. Populasi dalam penelitian ini berjumlah 760 orang dengan sampel 88 orang. Teknik pengumpulan data primer, teknik analisa data yang digunakan adalah uji chi square dan uji regresi berganda.Hasil: Hasil Uji Chi Square menunjukan bahwa terdapat hubungan signifikan antara umur (p=0.000) dan penggunaan kontrasepsi hormonal (p=0.002) dengan hasil uji regresi berganda (p-value0.05) menunjukan bahwa tidak ada pengaruh faktor risiko terhadap kejadian kanker payudara.Simpulan: Ada hubungan antara umur dan riwayat penggunaan kontrasepsi hormonal dengan kejadian kanker payudara. Tidak ada pengaruh faktor resiko terhadap kejadian kanker payudara. Kata Kunci: kanker payudara, riwayat penggunaan kontrasepsi hormonal, umur Risk Factors Related to Breast Cancer IncidenceIn the Edelweis Room of Ulin Hospital Banjarmasin AbstractBackground: Breast cancer is one of the leading causes of death in women in the world. So far, breast cancer most often affects women with an estimated 43.3% of new cancer cases diagnosed in 2012. The incidence of breast cancer varies globally where there is an increase in incidents in developing countries but tends to decrease in developed countries, with cases in the country developing (883,000 cases) developed countries (794,000 cases).Objective: Analyzing risk factors associated with breast cancer events include age, age at first menstruation, menopause, age at first marriage, history of use of hormonal contraception, history of breastfeeding, and history of breast cancer in the family.Method: This study is a quantitative study using analytical survey method with cross sectional design. The population in this study amounted to 760 people with a sample of 88 people. Primary data collection techniques, data analysis techniques used are chi square test and multiple regression test.Results: Chi Square test results showed that there was a significant relationship between age (p = 0,000) and hormonal contraceptive use (p = 0.002) with the results of multiple regression tests (p-value 0.05) indicating that there was no effect of risk factors on breast cancer incidence.Conclusion: There is a relationship between age and history of hormonal contraceptive use with the incidence of breast cancer. There is no effect of risk factors on the incidence of breast cancer. Keywords: breast cancer, history of hormonal contraceptive use, age


2017 ◽  
Vol 1 (01) ◽  
pp. 23
Author(s):  
Umi Faza ◽  
Dyah Umiyarni Purnamasari ◽  
Saryono Yono

Abstract  The aim of this study was to determine factors associated with diminished appetite in CKD patients undergoing hemodialysis therapy. This study is an observational analytic research with cross sectional design. Population of this study was CKD outpatients undergoing hemodialysis therapy in July- August 2016 in Prof. Dr. Margono Soekarjo Hospitals. Amount of 58 subjects taken by consecutive sampling. Appetite, sex, age, length of hemodialysis, frequency of nausea/vomiting, and depression were measured using questionnaire. Subjects who diminished appetite were 58,6%. More than half subjects were male (56,9%). Amount of 84,5% subjects were adults (19-59 years), 63,8% undergoing hemodialysis >1year, 39,7% experienced nausea/ vomiting and 53,4% were depression. Based on Chi-Square Test/ Fisher Exact Test, diminished appetite significantly associated with length of hemodialysis (p=0,041), frequency of nausea/vomiting (p=0,014), and depression (p=0,002). Dominant factors affected diminished appetite were depression and length of hemodialysis. Diminished appetite in CKD patients undergoing hemodialysis therapy associated with length of hemodialysis, frequency of nausea/vomit, and depression. Keyword : appetite, chronic kidney disease, hemodialysi  Abstrak Penelitian ini bertujuan untuk mengetahui faktor- faktor yang berhubungan dengan penurunan nafsu makan pada pasien Gagal Ginjal Kronik (GGK) yang menjalani terapi hemodialisis. Penelitian ini merupakan penelitian analitik observasional dengan pendekatan cross sectional. Populasi dari penelitian ini adalah pasien GGK rawat jalan yang menjalani terapi hemodialisis pada bulan Juli- Agustus 2016 di RSUD Prof. Dr. Margono Soekarjo Purwokerto. Sebanyak 58 subjek diambil dengan cara consecutive sampling. Nafsu makan, jenis kelamin, usia, lama hemodialisis, frekuensi mual/muntah, dan depresi diukur menggunakan kuesioner. Responden yang mengalami penurunan nafsu makan sebanyak 58,6%. Lebih dari separuh responden (56,9%) berjenis kelamin laki- laki dan 84,5% responden berusia dewasa (19-59 tahun). Sebanyak 63,8% responden menjalani hemodialisis >1tahun. Responden yang mengalami mual/muntah berat sebanyak 39,7% dan 53,4% mengalami depresi. Berdasarkan analisis bivariat menggunakan Uji Chi- Square/ Fisher Exact diperoleh hasil bahwa nafsu makan berhubungan secara signifikan dengan lama hemodialisis (p=0,041), frekuensi mual/ muntah (p=0,014), dan depresi (p=0,002). Faktor dominan yang mempengaruhi penurunan nafsu makan adalah depresi dan lama hemodialisis. Penurunan nafsu makan pada pasien GGK yang menjalani terapi hemodialisis berhubungan dengan lama hemodialisis, frekuensi mual/muntah, dan depresi. Kata kunci : gagal ginjal, hemodialisa, nafsu makan  


Author(s):  
Alviano Satria Wibawa ◽  
Hermina Novida ◽  
Muhammad Faizi ◽  
Deasy Ardiany

Introduction: Diabetic ketoacidosis (DKA) is a complication of diabetes mellitus which has a high risk of mortality. Mortality in DKA patients in developed countries is less than 5%, some other sources mention 5-10%, 2-10%, or 9-10%. Mortality events at clinics with simple facilities and elderly patients can reach 25-50%. The mortality rate of DKA patients is generally higher in infection conditions, especially in developing countries and in septic patients. Several factors such as age, sex, and high blood glucose can increase mortality risk of DKA patients. Other risk factors such as history of discontinued insulin therapy, impaired bicarbonate levels, pH, and increased leukocytes of DKA patients due to infection, abnormal albumin levels, electrolyte disturbances, and Serum Creatinine (SK) were thought to affect mortality of DKA patients. The purpose of this study was to determine the risk factors associated with mortality of DKA patients in Dr. Soetomo General Hospital Surabaya. Methods: The method used in this study was observational analytic involving 63 adult patients diagnosed with DKA with analysis using Chi-Square test. Results: From 63 patients included in this study, 37 patients diagnosed with DKA died and 26 patients lived. In a multivariate analysis, DKA severity with p = 0.001 (p < 0.005) was identified as having a relationship with mortality of DKA patients Dr. Soetomo General Hospital Surabaya. Conclusion: Severity is the only risk factor associated with mortality of DKA patients in Dr. Soetomo General Hospital Surabaya.


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