scholarly journals Bioactivity of Plant Extracts against Cowpea Bruchid Callosobruchus maculatus (Fab): A Review

2020 ◽  
Author(s):  
C. Shunmugadevi ◽  
S. Anbu Radhika
Keyword(s):  
Natural Products ◽  
Bioactive Compounds ◽  
Plant Extract ◽  
Plant Extracts ◽  
Callosobruchus Maculatus ◽  
Biological Activities ◽  
Botanical Insecticides ◽  
High Concentration ◽  
Plant Products ◽  
Wide Range

The objective of the present review is to know the bioactive compounds of the plant extract against Callosobruchus maculatus. Plants are able to produce a large number of bioactive compounds. Plant extract was found to have a wide range of bioactive compounds like Alkaloids, Carbohydrates, Starch, Glycosides, Flavonoids, Triterpenoids, Resins, Saponins, Steroid, Proteins and Tannins. The high concentration of phytochemicals protects against the Callosobruchus maculatus. Recent revelations have shown that synthetic insecticides were found to penetrate into grains and may be toxic. Natural products such as botanical insecticides may provide suitable alternatives. The review obviously designated that plant products have potentials of controlling Callosobruchus maculatus in stored cowpea as they are safe, free of residue and strong biological activities that are eco-friendly and biodegradable.

scholarly journals A Review: The extraction of active compound from Cymbopogon sp. and its potential for medicinal applications

2018 ◽  
Vol 5 (1) ◽  
pp. 82-98
Author(s):  
Shuhada A. Muttalib ◽  
Raihana Edros ◽  
Nor Azah M. A. ◽  
Rajaletchumy V. Kutty
Keyword(s):  
Pharmaceutical Industry ◽  
Bioactive Compounds ◽  
Plant Extracts ◽  
Active Compound ◽  
Biological Activities ◽  
Cymbopogon Citratus ◽  
High Demand ◽  
Pharmacological Activities ◽  
Wide Range ◽  
The Family

Cymbopogon citratus and Cymbopogon nardus are plants categorized under the family of Poaceae that have been recognized with high demand in pharmaceutical industry for its wide range of pharmacological activities. The potential bioactive compounds can be obtained either through traditional or conventional methods. The plant extracts are commonly used in numbers of products for culinary, pesticides and cosmetic purposes for its flavours and fragrances. Besides, bioactive compounds extracted from both species possess good biological activities that can be applied in the pharmaceutical field.

Mangrove Plants as a Source of Bioactive Compounds: A Review

2019 ◽  
Vol 9 (2) ◽  
pp. 86-97 ◽  
Author(s):  
Nilesh Lakshman Dahibhate ◽  
Ankush Ashok Saddhe ◽  
Kundan Kumar
Keyword(s):  
Natural Products ◽  
Bioactive Compounds ◽  
Raw Materials ◽  
Biological Activities ◽  
Enzyme Activation ◽  
The Novel ◽  
Coastal Forest ◽  
Low Oxygen ◽  
Wide Range ◽  
Harsh Conditions

Mangroves are unique coastal forest ecosystem distributed along the tropical and subtropical region of the world. They are evolutionarily adapted to combat against hostile environmental conditions such as low oxygen, high salinity, and temperature. The adaptive features endowed with novel secondary metabolic pathways and bioactive compounds to sustain in harsh conditions. The novel metabolites are a rich source of the wide range of bioactive compounds and natural products. It includes terpenoids, alkaloids, phenolics, saponins, flavonoids, and steroids. The bioactive and natural compounds may serve as therapeutic precursors and industrial raw materials. Terpenes and polyphenols have antiviral, antibacterial, antifungal, antimalarial, anticancer or combination of activities. To date, several mangroves plants were examined and recognized as a potential source of novel natural product for exploitation in medicine. In fact, most of the isolated compounds are novel and showed promising biological activities such as gastroprotective, cytotoxic, antioxidant, antibacterial, antifungal, antiviral, enzyme activation and inhibition, immunosuppressive, anti-inflammatory, antifeedant effects. In the present review, we have compiled the achievements and progress in mangroves natural products research of the last decade.

Pharmacologically potentials of different substituted coumarin derivatives

2019 ◽  
Author(s):  
Chem Int
Keyword(s):  
Benzene Ring ◽  
Bioactive Compounds ◽  
Biological Activities ◽  
Pharmacological Properties ◽  
Coumarin Derivatives ◽  
Wide Range ◽  
Anti Oxidant ◽  
Anti Inflammatory ◽  
Coumarin Compounds

Coumarin and its derivatives are widely spread in nature. Coumarin goes to agroup as benzopyrones, which consists of a benzene ring connected to a pyronemoiety. Coumarins displayed a broad range of pharmacologically useful profile.Coumarins are considered as a promising group of bioactive compounds thatexhibited a wide range of biological activities like anti-microbial, anti-viral,antiparasitic, anti-helmintic, analgesic, anti-inflammatory, anti-diabetic, anticancer,anti-oxidant, anti-proliferative, anti-convulsant, and antihypertensiveactivities etc. The coumarin compounds have immense interest due to theirdiverse pharmacological properties. In particular, these biological activities makecoumarin compounds more attractive and testing as novel therapeuticcompounds.

scholarly journals Modern Synthetic Methods for the Stereoselective Construction of 1,3-Dienes

Molecules ◽  
2021 ◽  
Vol 26 (2) ◽  
pp. 249
Author(s):  
Raquel G. Soengas ◽  
Humberto Rodríguez-Solla
Keyword(s):  
Organic Chemistry ◽  
Natural Products ◽  
Functional Group ◽  
Biological Activities ◽  
Synthetic Methods ◽  
Bond Forming ◽  
Drug Candidates ◽  
The Past ◽  
Wide Range

The 1,3-butadiene motif is widely found in many natural products and drug candidates with relevant biological activities. Moreover, dienes are important targets for synthetic chemists, due to their ability to give access to a wide range of functional group transformations, including a broad range of C-C bond-forming processes. Therefore, the stereoselective preparation of dienes have attracted much attention over the past decades, and the search for new synthetic protocols continues unabated. The aim of this review is to give an overview of the diverse methodologies that have emerged in the last decade, with a focus on the synthetic processes that meet the requirements of efficiency and sustainability of modern organic chemistry.

scholarly journals Effects of plant extracts on antioxidant status and oxidant-induced stress in Caco-2 cells

2007 ◽  
Vol 97 (2) ◽  
pp. 321-328 ◽  
Author(s):  
S. Aisling Aherne ◽  
Joseph P. Kerry ◽  
Nora M. O'Brien
Keyword(s):  
Dna Damage ◽  
Plant Extract ◽  
Plant Extracts ◽  
Antioxidant Status ◽  
Cell Injury ◽  
Membrane Integrity ◽  
Neutral Red ◽  
Dna Integrity ◽  
Cell Membrane Integrity ◽  
Wide Range

Experimental evidence suggests that most herbs and spices possess a wide range of biological and pharmacological activities that may protect tissues against O2-induced damage. The objectives of the present study were: first, to determine the effects of plant extracts on the viability, membrane integrity, antioxidant status and DNA integrity of Caco-2 cells and second, to investigate the cytoprotective and genoprotective effects of these plant extracts against oxidative stress in Caco-2 cells. The plant extracts examined were rosemary (Rosmarinus officinalis L.), oregano (Origanum vulgare L.), sage (Salvia officinalis L.) and echinacea (Echinacea purpurea L.). Cell membrane integrity was assessed by the lactate dehydrogenase release assay. Viability was determined by the neutral red uptake assay (NRUA) and the concentration of compound that resulted in 50 % cell death (IC50) was calculated. Antioxidant status of the cells was assessed by measuring GSH content, catalase activity and superoxide dismutase activity. To examine their cytoprotective and genoprotective effects, Caco-2 cells were pre-treated with each plant extract for 24 h followed by exposure to H2O2. DNA damage was assessed by the comet assay and cell injury was determined by the NRUA. Rosemary was the most toxic (IC50 123 μg/ml) and echinacea the least toxic (IC50 1421 μg/ml). Sage was the only plant extract to affect the antioxidant status of the cells by increasing GSH content. Sage, oregano and rosemary protected against H2O2-induced DNA damage (olive tail moment and percentage tail DNA), whereas protection against H2O2-induced cytotoxicity was afforded by sage only.

scholarly journals Chemical Diversity and Biological Activity of Secondary Metabolites Isolated from Indonesian Marine Invertebrates

Molecules ◽  
2021 ◽  
Vol 26 (7) ◽  
pp. 1898
Author(s):  
Fauzia Izzati ◽  
Mega Ferdina Warsito ◽  
Asep Bayu ◽  
Anggia Prasetyoputri ◽  
Akhirta Atikana ◽  
...  
Keyword(s):  
Natural Products ◽  
Bioactive Compounds ◽  
Marine Natural Products ◽  
Biological Function ◽  
Marine Invertebrates ◽  
Biological Activities ◽  
Structural Diversity ◽  
Chemical Diversity ◽  
Soft Corals ◽  
High Chemical

Marine invertebrates have been reported to be an excellent resource of many novel bioactive compounds. Studies reported that Indonesia has remarkable yet underexplored marine natural products, with a high chemical diversity and a broad spectrum of biological activities. This review discusses recent updates on the exploration of marine natural products from Indonesian marine invertebrates (i.e., sponges, tunicates, and soft corals) throughout 2007–2020. This paper summarizes the structural diversity and biological function of the bioactive compounds isolated from Indonesian marine invertebrates as antimicrobial, antifungal, anticancer, and antiviral, while also presenting the opportunity for further investigation of novel compounds derived from Indonesian marine invertebrates.

Ginger: A systematic review of clinical trials and recent advances encapsulation of their bioactive compounds

2022 ◽  
Author(s):  
Loleny Tavares ◽  
Slim SMAOUI ◽  
Cristian Pinilla ◽  
Hajer Ben Hlima ◽  
Helio Lopes Barros
Keyword(s):  
Systematic Review ◽  
Clinical Trials ◽  
Natural Products ◽  
Bioactive Compounds ◽  
Biological Activities ◽  
Health Benefits ◽  
Recent Advances

Recently, studies on natural products have considerably increased due to their exceptional biological activities and health benefits. Subsequently, their pharmacological attributes have played an immense role in detecting natural and...

scholarly journals Enhanced Recovery of Antioxidant Compounds from Hazelnut (Corylus avellana L.) Involucre Based on Extraction Optimization: Phytochemical Profile and Biological Activities

Antioxidants ◽  
2019 ◽  
Vol 8 (10) ◽  
pp. 460 ◽  
Author(s):  
Rusu ◽  
Fizeșan ◽  
Pop ◽  
Gheldiu ◽  
Mocan ◽  
...  
Keyword(s):  
Bioactive Compounds ◽  
Enhanced Recovery ◽  
Biological Activities ◽  
Natural Antioxidants ◽  
Antioxidant Compounds ◽  
Cancerous Cell ◽  
Wide Range ◽  
Quantitative Analyses ◽  
Corylus Avellana L

Tree nut by-products could contain a wide range of phytochemicals, natural antioxidants, which might be used as a natural source for dietary supplements. The aim of the present study was to evaluate the phenolic and sterolic composition, as well as the antioxidant and other biological activities, of hazelnut involucre (HI) extracts. Experimental designs were developed in order to select the optimum extraction conditions (solvent, temperature, time) using turbo-extraction by Ultra-Turrax for obtaining extracts rich in bioactive compounds. Qualitative and quantitative analyses were performed by LC-MS and LC-MS/MS and they revealed important amounts of individual polyphenols and phytosterols, molecules with antioxidant potential. The richest polyphenolic HI extract with the highest antioxidant activity by TEAC assay was further evaluated by other in vitro antioxidant tests (DPPH, FRAP) and enzyme inhibitory assays. Additionally, the cytotoxic and antioxidant effects of this extract on two cancerous cell lines and on normal cells were tested. This is the first study to analyze the composition of both hydrophilic and lipophilic bioactive compounds in HI extracts. Our findings reveal that this plant by-product presents strong biological activities, justifying further research, and it could be considered an inexpensive source of natural antioxidants for food, pharmaceutical, or cosmetic industry.

Biosynthesis of bioactive natural products from Basidiomycota

2019 ◽  
Vol 17 (5) ◽  
pp. 1027-1036 ◽  
Author(s):  
Hsiao-Ching Lin ◽  
Ranuka T. Hewage ◽  
Yuan-Chun Lu ◽  
Yit-Heng Chooi
Keyword(s):  
Natural Products ◽  
Bioactive Compounds ◽  
Biosynthetic Pathways ◽  
Bioactive Natural Products ◽  
Wide Range

The club fungi, Basidioycota, produce a wide range of bioactive compounds. Here, we describe recent studies on the biosynthetic pathways and enzymes of bioactive natural products from these fungi.

scholarly journals Natural Product Repertoire of the Genus Amphimedon

Marine Drugs ◽  
2018 ◽  
Vol 17 (1) ◽  
pp. 19 ◽  
Author(s):  
Nourhan Shady ◽  
Mostafa Fouad ◽  
Mohamed Salah Kamel ◽  
Tanja Schirmeister ◽  
Usama Abdelmohsen
Keyword(s):  
Secondary Metabolites ◽  
Natural Product ◽  
Bioactive Compounds ◽  
Biological Activities ◽  
Marine Sponges ◽  
Rich Source ◽  
Undescribed Species ◽  
Pharmacological Activities ◽  
Wide Range ◽  
Complete Survey

Marine sponges are a very attractive and rich source in the production of novel bioactive compounds. The sponges exhibit a wide range of pharmacological activities. The genus Amphimedon consists of various species, such as viridis, compressa, complanata, and terpenensis, along with a handful of undescribed species. The Amphimedon genus is a rich source of secondary metabolites containing diverse chemical classes, including alkaloids, ceramides, cerebrososides, and terpenes, with various valuable biological activities. This review covers the literature from January 1983 until January 2018 and provides a complete survey of all the compounds isolated from the genus Amphimedon and the associated microbiota, along with their corresponding biological activities, whenever applicable.

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