scholarly journals CRYSTALLOGRAPHIC ANALYSIS OF ORAL FLUID IN PATIENTS WITH POST-PROSTHETIC COMPLICATIONS DURING DENTAL IMPLANTATION IN THE COURSE OF TREATMENT

2020 ◽  
Vol 75 (3) ◽  
pp. 97-102
Author(s):  
D.V. Mikhalchenko ◽  
◽  
Yu.A. Makedonova ◽  
L.M. Gavrikova ◽  
◽  
...  
Keyword(s):  
Electrical Stimulation ◽  
Oral Fluid ◽  
Therapy Group ◽  
Group Iv ◽  
Transcranial Electrical Stimulation ◽  
Ozone Therapy ◽  
Traditional Therapy ◽  
Dental Implantation ◽  
Group I ◽  
Prosthetic Complications

The wedge-shaped dehydration method was used to assess the state of the oral fluid of patients with post-prosthetic complications during dental implantation against the background of various treatment methods. Oral fluid (saliva) was used as a material for the study. All patients were randomized into 4 equal groups in a 1: 1: 1: 1 ratio according to the methods of pharmacotherapy. Group I – 30 patients who underwent traditional treatment of post-prosthetic complications; Group II – 30 patients, ozone therapy was performed in addition to traditional therapy; Group III – 30 people who underwent transcranial electrical stimulation against the background of traditional therapy; Group IV – treatment of 30 people with the inclusion of a combination of ozone therapy and transcranial electrical stimulation in the treatment regimen. The control group consisted of healthy individuals of the same age group. Determined the nature of the organization of the structure of the salt and the distribution of the protein substance, depending on the concentration of protein in the biological fluid (saliva). Qualitative analysis of images of saliva crystallograms was carried out in the next (before treatment, 3 days, 7 days, and 14 days) observation and therapy. As the duration of treatment increased, the structuring of the crystal lattice took place, increasing in the series: patients with traditional therapy – patients with ozone therapy – patients with transcranial electrical stimulation – patients with combined use of ozone and transcranial electrical stimulation (group IV). Special attention should be paid to the fact that the complete normalization of the structure of the oral fluid facies occurred only during the complex therapy with ozone and TPP throughout the study.

Comparative analysis of the effectiveness of treatment of inflammatory post-prosthetic complications in dental implantation by the method of wedge-shaped dehydration

2021 ◽  
Vol 1 (12) ◽  
pp. 62-71
Author(s):  
Yu. A. Makedonova ◽  
D. V. Mikhalchenko ◽  
O. N. Kurkina ◽  
O. Yu. Afanaseva ◽  
S. A. Vargina ◽  
...  
Keyword(s):  
Electrical Stimulation ◽  
Comparative Analysis ◽  
Oral Fluid ◽  
Spatial Organization ◽  
Biological Fluids ◽  
Transcranial Electrical Stimulation ◽  
Polarization Microscopy ◽  
Ozone Therapy ◽  
Dental Implantation ◽  
Prosthetic Complications

Mucositis is one of the most common diseases during dental implantation. The genesis of the development of diseases, first of all, refers to microbiological factors. However, when conducting antimicrobial therapy, the success of the treatment is not always achieved. In this paper, a comparative analysis of the effectiveness of treatment of inflammatory post-prosthetic complications by modern methods is carried out by the method of wedge-shaped dehydration. The assessment of local crystal structures is an informative criterion in the assessment of the systemic organization of biological fluids, in particular, oral fluid. The most relevant method of visualizing the structural and spatial organization of the oral fluid is crystallographic research, the essence of which is a morphological study using light and polarization microscopy of a dried drop of oral fluid –facies. Patients in the first group received conventional treatment, the second group received ozone therapy, the third group received transcranial electrical stimulation, and the fourth group received a combination of ozone therapy and transcranial electrical stimulation. The crystallographic method was used to evaluate the qualitative and quantitative indicators of oral fluid, on the basis of which it can be concluded that the combined method is one of the objective, reliable methods for evaluating the effectiveness of treatment.

scholarly journals IMMUNOLOGICAL ASSESSMENT OF THE STRESS RESPONSE IN PATIENTS WITH INFLAMMATORY POSTPROTHETIC COMPLICATIONS

2021 ◽  
Vol 11 (2) ◽  
pp. 93-97
Author(s):  
Yuliya Makedonova ◽  
Dmitry Mikhalchenko ◽  
Oksana Kurkina ◽  
Olga Afanasyeva ◽  
Sergej Veremeenko ◽  
...  
Keyword(s):  
Stress Response ◽  
Conventional Therapy ◽  
Therapy Group ◽  
Transcranial Electrical Stimulation ◽  
Ozone Therapy ◽  
Dental Implantation ◽  
Psychoemotional State ◽  
Conventional Therapy Group ◽  
Pain Symptoms ◽  
Prosthetic Complications

Post-prosthetic complications during dental implantation are accompanied by pain symptoms leading to disorders of the psychoemotional state. All this influences the behavior of patients. In addition, psychoemotional stress is often a factor of provocation and persistence of the complications. The presence of a stress state in the identified pathology, as well as the influence of various therapies on the treatment of post-prosthetic complications, is reflected in the dynamics of changes in the concentrations of both catecholamines (epinephrine, norepinephrine) and glucocorticoids (cortisol) — hormones of the medulla and the adrenal cortex. The aim: to conduct an immunological analysis of the stress response in patients with postprosthetic complications during dental implantation. Materials and methods: The study was performed in 120 patients with post-prosthetic complications during dental implantation before and during treatment: Group I (control) — 30 patients treated with the conventional therapy; group II — 30 patients treated with ozone therapy in addition to the conventional therapy; group III — 30 patients treated with transcranial electrical stimulation in addition to the conventional therapy; Group IV — 30 patients treated with a combination of conventional therapy, ozone therapy and transcranial electrical stimulation. The concentration of epinephrine, norepinephrine, cortisol, alkaline phosphatase, and the Garkavi index were evaluated. Results: The change in these indicators after the treatment indicates the normalization of the level of the studied enzymes — markers of bone homeostasis, which is confirmed by an improvement in the clinical picture in the oral cavity. Conclusion: changes in immunological parameters objectively reflect the psychoemotional state of patients. The nature of changes in the hormonal stress response to the treatment of post-prosthetic complications indicates the effectiveness of the therapeutic regimens used, and, as a result, a decrease in both pain symptoms and psychoemotional stress.

Methods of application of ozone therapy for the treatment of peri-implantation mucositis

2021 ◽  
pp. 80-84
Author(s):  
Iu. A. Makedonova ◽  
D. V. Mikhalchenko ◽  
O. Yu. Afanaseva ◽  
S. V. Stavskaya ◽  
D. Yu. Dyachenko ◽  
...  
Keyword(s):  
Oral Cavity ◽  
Bone Destruction ◽  
The Body ◽  
Positive Trend ◽  
Ozone Therapy ◽  
Dental Implantation ◽  
Initial Stage ◽  
Local Exposure ◽  
Single Idea ◽  
Prosthetic Complications

At the dental reception, complications after dental implantation in the form of mucositis and peri-implantitis are becoming more and more common. There are quite a lot of risk factors for the development of inflammation of the parotid tissue, there is no single idea about the etiopathogenesis of the above pathology. Mucositis refers to the initial stage of peri-implantitis development and is reversible. The specialist should promptly diagnose the development of the inflammatory potential and start treatment, in order to prevent the development of bone destruction around the implants. One of the methods of local exposure to the lesion is ozone therapy.Goal. This paper describes the method of treatment of peri-implantation mucositis by ozone therapy.Materials and methods. In patients with peri-implantation mucositis, the inflammatory peri-implantation tissue was ozonated directly in the oral cavity with the Ozotron device in order to relieve inflammation and improve microcirculation in the oral cavity. Before performing oral ozonation, all patients underwent a general clinical examination to identify contraindications to this method. It also describes in detail the scheme that prevents the penetration of ozone into the body and prevents its ingestion.Results. During ozonation, a positive trend was obtained in the treatment of post-prosthetic complications during dental implantation. The developed scheme of ozonation in the oral cavity stops the inflammation of the peri-implantation tissue. Side effects and complications during ozone therapy directly in the oral cavity were not detected.Conclusions. The inclusion of ozone therapy in the treatment regimen of patients with peri-implantation mucositis is an appropriate and justified physiotherapy method. 

scholarly journals Sequelae from meningococcal meningitis in children: a critical analysis of dexamethasone therapy

2004 ◽  
Vol 62 (2b) ◽  
pp. 421-428 ◽  
Author(s):  
Erasmo Barbante Casella ◽  
Saul Cypel ◽  
André Alexandre Osmo ◽  
Yassuhiko Okay ◽  
Beatriz Helena Lefèvre ◽  
...  
Keyword(s):  
Therapy Group ◽  
Group Iv ◽  
Meningococcal Meningitis ◽  
University Hospital ◽  
Group Iii ◽  
Group I ◽  
Significant Difference ◽  
Dexamethasone Therapy ◽  
Meningitis In Children ◽  
Intellectual Level

OBJECTIVE: To evaluate the effectiveness of dexamethasone as an adjunctive therapy to antibiotics in children with meningococcal meningitis. METHOD: A total of 81 children diagnosed with meningococcal meningitis hospitalized in sequence were studied at the University Hospital of São Paulo University, with the objective of evaluating the presence of sequelae in four different groups of patients, following the administration of dexamethasone: Group I - 25 patients who received the first dose at least 10 minutes before the introduction of the antibiotic therapy; Group II - 19 patients who received the corticosteroid concomitantly; Group III - 14 patients for which the dexamethasone was administered after beginning the antibiotic scheme; Group IV - 23 patients that did not receive dexamethasone. The groups were evaluated for homogeneity through the prognostic indexes and clinical and laboratory characteristics, based on the records obtained at hospitalization. RESULTS: Some degree of sequelae occurred in 16 (26.22%) of the survivors and 23 patients (28.39%) coursed with sequelae or died. The mean period of neurological attendance was 36.97 months and neurological alterations were detected in 16.17% of the patients. No significant difference was found between the four groups. There was also no statistical difference in the comparison of the neurological sequelae in the children from group IV with the children of groups I and II or even with groups I, II and III analyzed as a whole. The presence of hearing loss occurred in 11.11% of the patients, again there was no significant difference between the four groups. Psychological evaluation was performed using the WPSSI and WISC tests. A mild mental disability was detected in one patient from group I and another in group III. The overall analysis of the sequelae (neurological, auditory and intellectual level) also did not demonstrate any significant difference between the four groups. Comparing the children from groups I and II together and also groups I, II and III as a whole with the children in group IV also failed to detect a significant difference arising from the use or nonuse of the corticosteroid. CONCLUSION: Dexamethasone was not proven to be effective in decreasing the number of sequelae among patients with meningococcal meningitis.

Transcranial Electrical Stimulation in Post-Stroke Cognitive Rehabilitation

2016 ◽  
Vol 21 (1) ◽  
pp. 55-64 ◽  
Author(s):  
Silvia Convento ◽  
Cristina Russo ◽  
Luca Zigiotto ◽  
Nadia Bolognini
Keyword(s):  
Electrical Stimulation ◽  
Cognitive Rehabilitation ◽  
Cognitive Disorders ◽  
Spatial Neglect ◽  
Transcranial Electrical Stimulation ◽  
Clinical Settings ◽  
Post Stroke ◽  
Neuropsychological Disorders ◽  
Current State ◽  
Stimulation Technique

Abstract. Cognitive rehabilitation is an important area of neurological rehabilitation, which aims at the treatment of cognitive disorders due to acquired brain damage of different etiology, including stroke. Although the importance of cognitive rehabilitation for stroke survivors is well recognized, available cognitive treatments for neuropsychological disorders, such as spatial neglect, hemianopia, apraxia, and working memory, are overall still unsatisfactory. The growing body of evidence supporting the potential of the transcranial Electrical Stimulation (tES) as tool for interacting with neuroplasticity in the human brain, in turn for enhancing perceptual and cognitive functions, has obvious implications for the translation of this noninvasive brain stimulation technique into clinical settings, in particular for the development of tES as adjuvant tool for cognitive rehabilitation. The present review aims at presenting the current state of art concerning the use of tES for the improvement of post-stroke visual and cognitive deficits (except for aphasia and memory disorders), showing the therapeutic promises of this technique and offering some suggestions for the design of future clinical trials. Although this line of research is still in infancy, as compared to the progresses made in the last years in other neurorehabilitation domains, current findings appear very encouraging, supporting the development of tES for the treatment of post-stroke cognitive impairments.

Anti-diabetic activity of diphenhydramine in diabetic rats

2020 ◽  
Vol 11 (4) ◽  
pp. 5067-5070
Author(s):  
Pang Jyh Chayng ◽  
Nurul Ain ◽  
Kaswandi Md Ambia ◽  
Rahim Md Noah
Keyword(s):  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Fasting Blood Glucose ◽  
Insulin Level ◽  
Diabetic Rats ◽  
Group Iv ◽  
Diabetic Rat ◽  
Control Group ◽  
Group I

The purpose of this project is to study the anti-diabetic effect of on a diabetic rat model. A total of Twenty male Sprague rats were used and it randomly distributed into four groups which are Group I: , Group II: negative control, Group III: and Group IV: and . In diabetic model were induced with via injection at the dosage of 65mg/kg. and FBG (Fasting Blood Glucose) level of diabetic rats were assessed every three days. Blood was collected via cardiac puncture at day 21 after the induction of treatment. Insulin level of the rats was assessed with the Mercodia Rat Insulin ELISA kit. FBG level of group I (12.16 ±3.96, p<0.05) and group IV (11.34 ±3.67, p<0.05) were significantly decreased. Meanwhile, the for all rats did not show any significant increase. However, the insulin level was escalated in group IV (0.74+0.25, p<0.05) significantly. The present study shows that the and the combination of and lowered blood glucose level and enhanced insulin secretion.

Different Treatment Protocols of Retained Fetal Membranes and its Effect on Serum Profile, Uterine Involution and Postpartum Fertility in Cows

2019 ◽  
Vol 14 (04) ◽  
Author(s):  
A. I. Shah ◽  
D. M. Patel ◽  
N. P. Sarvaiya ◽  
S. P. Madhira
Keyword(s):  
Group Iv ◽  
Fetal Membranes ◽  
Serum Progesterone ◽  
Group V ◽  
Manual Removal ◽  
Uterine Involution ◽  
Group I ◽  
Medicinal Treatment ◽  
Group Ii ◽  
Postpartum Estrus

This study was undertaken on 36 freshly calved cows randomly divided into 6 equal groups under field conditions. Cows of group-VI that shed placenta within 8-12 hours postpartum naturally served as healthy control. The cows with retained fetal membranes (RFM, n = 18) for more than 12 hrs were managed either by manual removal of placenta without antibiotics (group-I), parenteral antibiotic (Ceftiofur 1 g i/m) for three consecutive days (group-II) or a combination of both (group-III). In group-IV and group-V, cows were administered with Inj. Oxytocin @ 50 IU i/m and Inj. Dinoprost tromethamine (PGF2α) @ 25 mg i/m, respectively, immediately after parturition and time of placental shedding was recorded. The overall prevalence of Brucellosis by RBPT was found to be 5.55 % amongst these 36 animals. The placental expulsion in groups following medicinal treatment was found to be 50 (3/6) % in Ceftiofur alone by 3 days (group-II), and 66.67 (4/6) % in Oxytocin (group-IV) and 100 (6/6) % in PGF2α inj. (group-V) groups within 12 hrs. The time of uterine involution in groups I to VI was found to be 42.00 ± 1.94, 39.50 ± 0.99, 40.67 ± 1.39, 38.33 ± 1.55, 37.50 ± 1.02 and 37.33 ± 1.76 days, respectively, while the interval for the appearance of first postpartum estrus was 54.83 ± 2.06, 51.00 ± 1.05, 52.17 ± 1.96, 50.17 ± 2.03, 48.67 ± 1.90 and 49.17 ± 1.55 days, respectively, which did not vary statistically. The mean serum progesterone profile obtained on day 0 and day 21 postpartum was statistically non-significant between groups. However, it was significantly (p less than 0.05) lower on day 0 as compared to day 21 in group-I, II and VI. The levels on day 0 coincided with the time of blood sampling after calving. The high level of serum P4 on day 0 in group-IV and V could be due to sampling immediately after calving. The serum calcium and phosphorus levels were significantly(p less than 0.05) lower on day 0 than on day 21, but not the magnesium. The group effect was however non-significant for any of three minerals. It was observed that manual removal of RFM without parenteral antibiotics, resulted in puerperal metritis, cervicitis, pyometra which ultimately resulted into delayed uterine involution, delayed first postpartum estrus and thus, reduced the postpartum reproductive efficiency. It was inferred that the PGF2α and Oxytocin injections could be used as a treatment of choice for prevention of RFMs in cattle.

scholarly journals The Effectiveness Of Quadriceps Strengthening Exercises Combined With Neuromuscular Electrical Stimulation on Patellofemoral Pain Syndrome

2017 ◽  
Vol 5 (2_suppl2) ◽  
pp. 2325967117S0010
Author(s):  
Sezen Karabörklü Argut ◽  
Nilgün Türker ◽  
Derya Çelik ◽  
Önder İsmet Kılıçoğlu
Keyword(s):  
Electrical Stimulation ◽  
Muscle Strength ◽  
Neuromuscular Electrical Stimulation ◽  
Pain Syndrome ◽  
Quadriceps Strength ◽  
Patellofemoral Pain ◽  
Group I ◽  
Strengthening Exercises ◽  
Group Ii ◽  
And Function

Objective: The weakness of the quadriceps strength in patellofemoral pain syndrome (PFPS) is very evident. Therefore, quadriceps strengthening exercises are very important part of the rehabilitation program. Neuromuscular Electrical Stimulation (NMES) is considered one of the methods for increasing quadriceps muscle strength. To evaluate the effectiveness of combined NMES and strengthening exercises to improve the recovery of quadriceps strength and function in patients with PFPS. Methods: This study was planned as a randomized controlled pilot study. A total of 27 patients (mean age=38.9±10.8 years, range=20-60 years; 16 females) with PFPS were assessed and randomly assigned into 2 groups. Group I received a standard program (quadriceps strengthening, hip strengthening and hamstring stretching) and NMES combined with quadriceps strengthening exercises simultaneously. Group II received the same standard program without NMES. Both groups were enrolled 3 times per week for 40 minutes per day in 6 weeks. Patients were assessed at the baseline, 3 rd, 6th, and 12th weeks of treatment. Quadriceps strength was evaluated by isokinetic dynamometer. The range of motion at testing was set between 0 for extension to 90 for flexion. The test was performed at 60 degrees/sn and concentric maximum peak torque value was recorded. Kujala and Lysholm scores were used for functional assessments. The data were analyzed using the SPSS 20.0. Shapiro-Wilk test was used to assess the distribution of data. The changes in dependent variables before treatment, 3 rd, 6th, and 12th weeks were analyzed using a 2 by 4 mixed-model analysis of variance (ANOVA). Pairwise comparisons with paired t test were used to determine whether the Group I or Group II, has changed over time. An intention- to- treat analysis was performed to impute values for missing data. An alpha level of 0.05 was established. Results: The study was completed with 20 patients. Group I (n=10; mean age=39.4±8.5 years; 7 females) and group II (n=10; mean age=43.2±11.7 years; 5 females) had no differences in pre-operative measures (p>.05). There was significant improvements in within groups statistics of all parameters for both groups (p<.05). No differences in quadriceps strength, Kujala and Lysholm scores between groups were found at the different time points (F= 0.86; p = 0.12, F=0,001; p =0.97, F=0.12; p=0.73, respectively) Conclusion: NMES combined with quadriceps strengthening exercises has no additional effect on PFPS patients’ on muscle strength and function. When considering these results, we believe that there is no need to continue the study in progress. [Table: see text]

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