scholarly journals Enterosorption in the Treatment of Heavy Metal Poisoning

Author(s):  
Sergey Mikhalovsky ◽  
Oleksandr Voytko ◽  
Violetta Demchenko ◽  
Pavlo Demchenko

Enterosorption is a cost-effective and efficient approach to reducing the impact of chronic exposure to heavy metals and radionuclides. As an auxiliary method to medical treatment, it can protect population chronically exposed to the intake of heavy metals or radioactivity due to industrial activities or in the aftermath of technogenic or natural accidents. This paper assesses the current state of the art in the treatment of acute and chronic heavy metal poisoning.

Author(s):  
Suryabhan Shriram Dongre ◽  
Vidhyashree Thorat

Aims and objectives: To study the views of Doctors on heavy metal poisoning in Mumbai      Material and methods: Heavy metals, like arsenic, lead, mercury, and others, are all around us. They’re in the ground we walk on, in the water we drink, and in the products we use every day. But high levels of most heavy metals can make you sick. While our bodies need small amounts of some heavy metals — such as  zinc, copper, chromium, iron, and manganese — toxic amounts are harmful. If our body's soft tissues accumulate too much of heavy metals, the resulting poisoning can cause serious damage. Though there are variety of medical uses of heavy metals, still each metal has its own side effects which disturb human health. We have to use  solid evidence that demonstrates the safety, efficacy, and effectiveness of specific alternative medicine . Also We have to study General biocompatibility (how metals react with human tissue) and Immunological biocompatibility (The adverse reaction due to an immunological  or allergic type response from metals). For the better study of heavy metal toxicity, we have carried out survey taking opinions of Doctors in Mumbai and Thane region. Observations: Commonly found views are  : In most of the medicines Doctors identify Lead as poisonous, Most of the metal poisoning cases occur accidentally, Ayurvedic medicines should be standardized by Ayurvedic parameters so that metals will not be in free form & never cause toxicity,  use of herbal preparations is the alternative to medicines containing metals. Conclusion: From the survey of heavy metal poisoning we conclude that there are herbal drugs which function as  the alternative solutions for the use of heavy metals , Other medicines can be used after the proper detoxification of heavy metals.


2018 ◽  
Vol 09 (03) ◽  
pp. 431-433
Author(s):  
Sowmini R. Perumal ◽  
Sakthi Velayudham ◽  
K. Malcolm Jeyaraj ◽  
S. Arunan ◽  

ABSTRACTMorvan's syndrome is an autoimmune disorder of peripheral and central nervous system mediated by VGKC antibody. Here we report a case of Morvans syndrome who presented 1 month after ayurvedic drug intake. She presented with symptoms of peripheral nerve hyperexcitablity and autoimmune testing revealed positive result for VGKC antibody. Heavy metals level was also significantly raised. She improved after a course of steroids. This case report tries to highlight the association of VGKC mediated Morvans syndrome with heavy metal poisoning and its incidental occurence after Ayurvedic drug intake.


2019 ◽  
Vol 8 (2) ◽  
pp. 69-77 ◽  
Author(s):  
Reza Mehrandish ◽  
Aliasghar Rahimian ◽  
Alireza Shahriary

Some heavy metals are nutritionally essential elements playing key roles in different physiological and biological processes, like: iron, cobalt, zinc, copper, chromium, molybdenum, selenium and manganese, while some others are considered as the potentially toxic elements in high amounts or certain chemical forms. Nowadays, various usage of heavy metals in industry, agriculture, medicine and technology has led to a widespread distribution in nature raising concerns about their effects on human health and environment. Metallic ions may interact with cellular components such as DNA and nuclear proteins leading to apoptosis and carcinogenesis arising from DNA damage and structural changes. As a result, exposure to heavy metals through ingestion, inhalation and dermal contact causes several health problems such as, cardiovascular diseases, neurological and neurobehavioral abnormalities, diabetes, blood abnormalities and various types of cancer. Due to extensive damage caused by heavy metal poisoning on various organs of the body, the investigation and identification of therapeutic methods for poisoning with heavy metals is very important. The most common method for the removal of heavy metals from the body is administration of chemical chelators. Recently, medicinal herbs have attracted the attention of researchers as the potential treatments for the heavy metals poisoning because of their fewer side effects. In the present study, we review the potential of medicinal herbs such as: Allium sativum (garlic), Silybum marianum (milk thistle), Coriandrum sativum (cilantro), Ginkgo biloba (gingko), Curcuma longa (turmeric), phytochelatins, triphala, herbal fibers and Chlorophyta (green algae) to treat heavy metal poisoning.


Author(s):  
V.I. Dorozhkin ◽  
◽  
G.I. Pavlenko ◽  
N.A. Brichko ◽  
N.S. Pavlova ◽  
...  

The feed additive L-cysteine ​​in a therapeutic dose was used for 2 months against the background of poisoning of white rats with a combination of lead and cadmium at a level of 10 MPC (50 and 5 mg / kg, respectively). The maximum accumulation of heavy metals was found in the kidneys (Pb up to 8,15 mg / kg, Cd 2,51 mg / kg) and liver (Pb up to 7,44 mg / kg, Cd 1,80 mg / kg) of rats. With the introduction of L-cysteine ​​into the feed, the content of lead decreased by 2 times and cadmium by 2 ... 4 times in all investigated organs. Thus, L-cysteine has shown a fairly complete protective effect in heavy metal poisoning and can be recommended as a means that can reduce heavy metal (HM) intoxication.


2021 ◽  
Vol 68 (3) ◽  
pp. 415-418
Author(s):  
Alina Epure ◽  
◽  
Dan Mircea Cheța ◽  
◽  

Mercury and aluminum poisoning affects the entire human body, the cumulative toxic effects being noticed especially at the cognitive, neurological and metabolic level. Toxicity with heavy metals such as mercury, aluminum, arsenic, lead is one of the biggest threats to our health. The diagnosis of mercury, aluminum and arsenic poisoning is an important step in establishing food and chelation therapy, with an emphasis on the cause, not on the symptoms. We present the case of a 46-year-old patient with symptoms manifested for a period of 2 years, who was exposed to treatments structured according to manifestations, without improving the conditions presented, without performing specific investigations of heavy metal poisoning. The personalized diet and treatment plan, used in the case of this patient, for a period of 3 months were distinguished by a total solution of the manifestations initially presented, no side effects.


Author(s):  
Florian Kuisat ◽  
Fernando Lasagni ◽  
Andrés Fabián Lasagni

AbstractIt is well known that the surface topography of a part can affect its mechanical performance, which is typical in additive manufacturing. In this context, we report about the surface modification of additive manufactured components made of Titanium 64 (Ti64) and Scalmalloy®, using a pulsed laser, with the aim of reducing their surface roughness. In our experiments, a nanosecond-pulsed infrared laser source with variable pulse durations between 8 and 200 ns was applied. The impact of varying a large number of parameters on the surface quality of the smoothed areas was investigated. The results demonstrated a reduction of surface roughness Sa by more than 80% for Titanium 64 and by 65% for Scalmalloy® samples. This allows to extend the applicability of additive manufactured components beyond the current state of the art and break new ground for the application in various industrial applications such as in aerospace.


Foods ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 1310
Author(s):  
Matúš Várady ◽  
Sylwester Ślusarczyk ◽  
Jana Boržíkova ◽  
Katarína Hanková ◽  
Michaela Vieriková ◽  
...  

The aim of this study was to determine the effect of roasting on the contents of polyphenols (PPH), acrylamide (AA), and caffeine (CAF) and to analyze heavy metals in specialty coffee beans from Colombia (COL) and Nicaragua (NIC). Samples of NIC were naturally processed and COL was fermented anaerobically. Green beans from COL (COL-GR) and NIC (NIC-GR) were roasted at two levels, light roasting (COL-LIGHT and NIC-LIGHT) and darker roasting (COL-DARK and NIC-DARK), at final temperatures of 210 °C (10 min) and 215 °C (12 min), respectively. Quantitative analyses of PPH identified caffeoylquinic acids (CQA), feruloylquinic acids, and dicaffeoylquinic acids. Isomer 5-CQA was present at the highest levels and reached 60.8 and 57.7% in COL-GR and NIC-GR, 23.4 and 29.3% in COL-LIGHT and NIC-LIGHT, and 18 and 24.2% in COL-DARK and NIC-DARK, respectively, of the total PPH. The total PPH contents were highest in COL-GR (59.76 mg/g dry matter, DM). Roasting affected the contents of PPH, CAF, and AA (p < 0.001, p < 0.011 and p < 0.001, respectively). Nickel and cadmium contents were significantly higher in the COL-GR than in the NIC-GR beans. Darker roasting decreased AA content, but light roasting maintained similar amounts of CAF and total PPH.


Author(s):  
Pedro Alexandre Sodrzeieski ◽  
Leonardo Capeleto de Andrade ◽  
Tales Tiecher ◽  
Flávio Anastácio de Oliveira Camargo

Dilúvio Stream flows through an area with a great population density in Porto Alegre, Southern Brazil. The anthropogenic influence in the surroundings impacted negatively the quality of the sediments of Dilúvio Stream and Lake Guaíba. This study evaluated the physico-chemical variability of surface sediments in a non-channeled section of Dilúvio Stream. Additionally, we compared the concentration of several heavy metals in this section with data from previous studies in the margins of Lake Guaíba near the outflow of Dilúvio Stream in order to evaluate the impact of urbanization on sediment pollution. The pH, bulk density, particle-size distribution, electrical conductivity, organic carbon, assimilable phosphorus, total nitrogen, mineralogical composition (X-ray diffractogram) and pseudo total concentration of several metals (Fe, Al, Ca, Mg, Na, K, Mn, Ba, Zn, V, As, Pb, Cu, Cr, Co, Ni, Cd, Mo, and Se) were evaluated. The results showed that the sediments in the non-channeled section of Dilúvio Stream are predominantly sandy, with heavy metal contents below the quality reference values. Quartz and feldspar predominated in all sites. The concentration of Zn, Pb, Cu, Cr, and Ni were lower than that observed in the margins of Lake Guaíba near the outflow of Dilúvio Stream, possibly due to pollution input throughout the channeled section. The Dilúvio Stream shows indications of an anthropogenic influence in the heavy metals concentration through the channeled area.


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