scholarly journals The Pathophysiology and Outcomes of Diabetic Patients with Coronavirus Disease 2019 (COVID-19)

2021 ◽  
Vol 4 (2) ◽  
pp. 124
Author(s):  
Victor Perdana Kusuma ◽  
Deasy Ardiany

Introduction: Coronavirus Disease 2019 (COVID-19) is a respiratory tract infection caused by the SARS-CoV-2 virus, which was announced a pandemic by the World Health Organization (WHO) on March 11, 2020. On March 2, 2020, two confirmed cases of COVID-19 were initially reported in Indonesia. COVID-19 has been reported in 96.2 million people around the world. COVID-19 has already stolen the lives of almost 2 million individuals. Diabetes mellitus patients face an additional challenge with this disease (DM). Several studies have found a link between diabetes mellitus and COVID-19, as well as a bad prognosis for persons with DM and COVID-19. Aim of this study was to learn more about the link between diabetes and COVID-19, as well as the pathophysiology of diabetes.Methods: We searched for articles in PubMed and Google Scholar databases till February 2021, with the following keywords: “SARS-CoV-2”, “COVID-19”, “infection”, “pathogenesis”, “diabetes”Results: Diabetes Mellitus increased the severity and mortality of COVID-19 patients due to mechanisms involving inflammation and immune system activation, increased coagulation activity, oxidative stress, glucotoxicity, endoplasmic reticulum stress, renin-angiotensin-aldosterone system disorders, apoptotic mechanisms, mitochondrial dysfunction, and damage to pancreatic beta cells. COVID-19 infection can also lead to hyperglycemia and new-onset diabetes.Conlusion: Diabetes Mellitus is one of the comorbidities linked to a worse COVID-19 prognosis, according to the findings of this literature study. Furthermore, current research suggests that COVID-19 might cause hyperglycemia or new-onset diabetes, which has a poorer prognosis than COVID-19 patients with pre-existing diabetes.

2021 ◽  
Vol 2 (6) ◽  
pp. 53-56
Author(s):  
Irina A. Novikova ◽  
◽  
Tatiana M. Panina ◽  

Type 2 diabetes mellitus is a violation of carbohydrate metabolism caused by insulin resistance and relative insulin insufficiency or a violation of insulin secretion with or without insulin resistance. The number of people with diabetes increased from 108 million in 1980 to 422 million in 2014. The World Health Organization (WHO) predicts that by 2030 this number will increase to 439 million, which is almost 10% of the adult population. A dentist is often the first to encounter manifestations of diabetes mellitus in the oral cavity, such as caries, candidiasis, dryness, inflammatory periodontal diseases, etc. Therefore, timely diagnosis and close interaction of doctors of different specialties is crucial for the treatment of this disease.


2011 ◽  
Vol 8 (1) ◽  
pp. 32-39 ◽  
Author(s):  
A V Kosygina

In recent decades, overweight and obesity have become a major problem for most countries. According to the World Health Organization (WHO), more than a billion people worldwide are overweight and more than 300 million are obese. These clinical and experimental studies highlight a clear relationship between obesity and several chronic diseases such as type 2 diabetes mellitus (T2DM), atherosclerosis, coronary heart disease, high risk of oncological diseases, disorders of the reproductive sphere, pathology of the musculoskeletal system, as well as deviations in mental status and processes of social adaptation. Therefore, considerable efforts of modern endocrinology focused on the study of etiopathogenetic aspects that underlie these diseases and identification of possible markers.


2021 ◽  
Vol 5 (1) ◽  
pp. 114-124
Author(s):  
Miftahul Ulfah

ABSTRACTThe spreading of a new corona virus named Covid-19 has caused so many death tolls to almost all countries in the world. Researchers suspect that this virus originated from the traditional market in China's Wuhan City selling a wide variety of fresh wet animals traded for consumption, including bats and pangolins which ultimately transmit the virus to humans. The World Health Organization has confirmed that Covid-19 transmission through droplets or sparks from infected people through talking, sneezing or coughing. With such causes, world governments recommend and even order the citizens to always maintain health and hygiene by washing hands, wearing masks, and covering mouths when sneezing or coughing. While in Islam, there are also procedures for behaving to maintain health and cleanliness. This literature study used qualitative method to examine the relevance of the global pandemic to the Islamic character education. This study then found that the influence of Covid-19 on the application of character education and Islamic education. This conclusion could be seen from the factors that influence the majority of characters carried out during the Covid-19 plague including instincts, habits, wills and conscience.Keywords: Application, Character Education, Covid-19, Islamic Education


Author(s):  
SHYI-MING CHEN ◽  
YUN-HOU HUANG ◽  
RUNG-CHING CHEN

Diabetes mellitus is a common chronic disease in recent years. According to the World Health Organization, the estimated number of diabetic patients will increase 56% in Asia from the year 2010 to 2025, where the number of anti-diabetic drugs that doctors are able to utilize also increase as the development of pharmaceutical drugs. In this paper, we present a recommendation system for anti-diabetic drugs selection based on fuzzy reasoning and ontology techniques, where fuzzy rules are used to represent knowledge to infer the usability of the classes of anti-diabetic drugs based on fuzzy reasoning techniques. We adopt the "Medical Guidelines for Clinical Practice for the Management of Diabetes Mellitus" provided by the American Association of Clinical Endocrinologists to build the ontology knowledge base. The experimental results show that the proposed anti-diabetic drugs recommendation system gets the same accuracy rate as the one of Chen et al.'s method (R. C. Chen, Y. H. Huang, C. T. Bau and S. M. Chen, Expert Syst. Appl.39(4) (2012) 3995–4006.) and it is better than Chen et al.'s method (R. C. Chen, Y. H. Huang, C. T. Bau and S. M. Chen, Expert Syst. Appl.39(4) (2012) 3995–4006.) due to the fact that it can deal with the semantic degrees of patients' tests and can provide different recommend levels of anti-diabetic drugs. It provides us with a useful way for anti-diabetic drugs selection based on fuzzy reasoning and ontology techniques.


2021 ◽  
Vol 4 (1) ◽  
pp. 181-187
Author(s):  
Rian Hazni ◽  
Ricki Gustiawan ◽  
Zulfian Zulfian ◽  
Sri Maria Puji Lestari ◽  
Resti Arania ◽  
...  

ABSTRAK Menurut World Health Organization (WHO) tahun 2011 jumlah penderita diabetes melitus di dunia 200 juta jiwa, Indonesia menempati urutan keempat terbesar dalam jumlah penderita diabetes melitus di dunia setelah India, Cina,dan Amerika Serikat. Pada tahun 2011,terdapat sekitar 5,6 juta penduduk Indonesia yang mengidap diabetes mellitus. Sementara itu di Dinas Kesehatan Provinsi Lampung tercatat bahwa pada tahun 2014 persentase penderita DM tipe II sejumlah 1,5% per 100.000 atau sebanyak 5.560. Tujuan dari kegiatan ini adalah untuk meningkatkan pengetahuan akan pentingnya menjaga kesehatan untuk mencegah terjadinya Diabetes Mellitus. Metode yang digunakan dalam kegiatan ini yaitu penyuluhan kepada masyarakat yang mengunjungi Puskesmas Rawat Inap Sukaraja Bandar Lampung. Pelaksanaan kegiatan dibantu oleh mahasiswa FK Universitas Malahayati Bandar Lampung pada 22 Desember 2020. Hasil dari kegiatan ini adalah meningkatnya pengetahuan masyarakat sehingga dapat disimpulkan bahwa penyuluhan pada masyarakat sangat efektif. Kata Kunci: Penyuluhan, Diabetes Melitus, Masyarakat ABSTRACT According to the World Health Organization (WHO) in 2011 the number of diabetes mellitus sufferers in the world was 200 million people, Indonesia was fourth in the number of diabetes mellitus sufferers in the world after India, China and the United States. In 2011, there were approximately 5.6 million Indonesians who had diabetes mellitus. Meanwhile in the Lampung Provincial Health Office, it was recorded that in 2014 the proportion of people with type II DM was 1.5% per 100,000 or as much as 5,560. The purpose of this activity is to increase knowledge about maintaining health to prevent Diabetes Mellitus. The method used in this activity was counseling to the public who visited the Sukaraja Bandar Lampung Puskesmas. Implementation of activities assisted by students of FK Malahayati University in Bandar Lampung on December 22, 2020. The result of this activity is public knowledge so it can be ignored that community education is very effective. Keywords: Counseling, Diabetes Mellitus, community 


SOEROPATI ◽  
2019 ◽  
Vol 2 (1) ◽  
pp. 87-98
Author(s):  
Audyati Gany ◽  
Kartika Suhada ◽  
Cindra Paskaria ◽  
Meilinah Hidayat

Diabetes Mellitus is a chronic metabolic disorder which is a serious problem for the health of the people of Indonesia and the world, so the International Diabetes Federation (IDF) and the World Health Organization (WHO) set November 14 as World Diabetes Day. The aim of the research is to increase public knowledge about Diabetes Mellitus, to behave and behave as they should in their daily lives, starting with lifestyle and patterns of food and drink intake. Counseling is carried out to PKK cadres as the spearhead who continue to the community members. The study design was a lecture accompanied by cross sectional pre and post test data collection. The results of the knowledge aspects of the study showed that there was a very significant difference between the pre and post test results (p = 0,000). The attitude aspect showed that there was no significant difference between the pre and post test results (p = 0.257), but overall the cadre's attitude regarding a healthy lifestyle to prevent Diabetes Mellitus was good enough. Behavioral aspects indicate that there are respondents who behave well, a maximum value of 3, but some are not good, a minimum value of 0. The results of blood sugar tests when showing as many as 69.57% of participants are not certain to have DM, while the rest are not DM. The conclusion is that there is a very significant increase in PKK cadre knowledge, but there has not been a significant change in attitude after attending counseling.


2020 ◽  
Author(s):  
KhP Takhchidi ◽  
NKh Takhchidi ◽  
MKh Movsesian

The end of 2019 in China was marked by the breakout of the new Coronavirus Disease (COVID-19) caused by the severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2). Gradually, the infection spread around the world and in March 2020, the World Health Organization (WHO) declared Covid-19 a pandemic. The new coronavirus disease 2019 is highly contagious, causing respiratory distress syndrome and poses a huge threat to public health, especially in patients. with serious concomitant diseases such as diabetes mellitus, bronchial asthma, hypertension, etc. Many scientists have put forward the idea that COVID-19 can be transmitted through the eyes through contact and everyday life. Over the past six months, works on the ocular manifestations of coronavirus infection have begun to appear in the literature. We conducted a systematic review of scientific articles from the PubMed, e-Library, Scopus databases in order to conduct a meta-analysis of the effect of coronavirus infection on the eyes and its ophthalmological manifestations.


2021 ◽  
Vol 3 (12) ◽  
pp. 976-987
Author(s):  
Zuhria Wahidah Nurhidayah ◽  
Rara Warih Gayatri ◽  
Suci Puspita Ratih

Abstract: Cigarettes are one of the factors of world health issues that have not been resolved until now. The number of smokers in the world in 2015 reached 1.3 billion people, while Indonesia being the first billion smokers in ASEAN with 65 million smokers and 69 percent dominated by teenagers. The World Health Organization (WHO) has determined the reduction of cigarette consumption as one of the Global NCDs Targets to be achieved by 2025 by increasing the action of increasing the tax price of all cigarette products to reduce the demand for cigarettes. Indonesia applies the same thing by issuing the Peraturan Menteri Keuangan Republik Indonesia no. 198 Tahun 2020 concerning the policy on the price of cigarettes smoking 12.5 percent in order to reduce the prevalence of smoking in the 10-18 year age range from 9.1 percent to 5.4 percent in 2029 according to the RPJMN. The purpose of this study is to analyze research studies that have been conducted to describe the effect of rising cigarette prices on adolescent smoking behavior. The data used in this literature study are articles that are relevant to the inclusion and exclusion criteria that have been determined within a span of 10 years that have been published in selected databases, which are Proquest, Pubmed, and Google Scholar. Stages of selection using the PRISMA flow chart. Assessment of article quality used the Strengthening The Reporting of Observational Studies in Epidemiology (STROBE) checklist. The results of this literature study contained 7 (seven) articles that were analyzed. These articles describe the effect of increasing cigarette prices on decreasing smoking initiation, smoking consumption, and smoking prevalence. Abstrak: Rokok merupakan salah satu faktor masalah kesehatan dunia yang belum terselesaikan sampai saat ini. Jumlah perokok di dunia pada tahun 2015  diestimasikan mencapai 1,3 milyar orang di mana Indonesia menempati peringkat pertama perokok terbesar di ASEAN dengan jumlah 65 juta perokok dan 69 persen didominasi remaja. World Health Organization (WHO) menetapkan pengurangan konsumsi rokok sebagai salah satu Global NCDs Target yang akan dicapai pada tahun 2025 dengan prioritas aksi peningkatan harga pajak semua produk rokok untuk mengurangi permintaan rokok. Indonesia menerapkan hal serupa yaitu dengan mengeluarkan Peraturan Menteri Keuangan Republik Indonesia nomor 198 Tahun 2020 mengenai kebijakan harga rokok yang dinaikkan 12,5 persen guna menekan prevalensi merokok remaja rentang usia 10 – 18 tahun dari angka 9,1 persen menjadi 5,4 persen di tahun 2029 sesuai dengan RPJMN. Tujuan dari penelitian ini yaitu untuk menganalisis studi-studi penelitian yang telah dilakukan untuk menggambarkan pengaruh dari kenaikan harga rokok terhadap perilaku merokok remaja. Data yang digunakan dalam studi literatur ini merupakan artikel-artikel yang relevan dengan kriteria inklusi dan eksklusi yang telah ditentukan dengan rentang 10 tahun yang telah terpublikasi pada database pilihan yaitu Proquest, Pubmed, dan Google Scholar. Tahapan seleksi menggunakan PRISMA flow diagram. Penilaian kualitas artikel menggunakan Strengthening The Reporting of Observational Studies in Epidemiology (STROBE) checklist. Hasil pada studi literatur ini terdapat 7 (tujuh) artikel yang dianalisis. Artikel-artikel tersebut menggambarkan adanya pengaruh kenaikan harga rokok terhadap penurunan inisiasi merokok, konsumsi merokok, dan prevalensi merokok.


2000 ◽  
Vol 8 (2) ◽  
pp. 153-172 ◽  
Author(s):  
M Perera ◽  
MA Lumsden

Diabetes mellitus is the most common chronic disease in the industrialized world. In North America and Europe the prevalence in adults is 7–8% and it is estimated that there are more than 100 million cases worldwide. With the increasing prevalence of non-insulin-dependent diabetes mellitus (NIDDM) this figure continues to rise. The World Health Organization predicts that the number of patients with diabetes will rise from 130 million to over 300 million over the next 25 years. Diabetes affects 1 in 30 people living in England and Wales and accounts for more than £2 billion of hospital costs annually. The number of diabetic patients in the UK is predicted to double to 3 million by the year 2010.


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