scholarly journals The role of Kuniran (U. moluccensis) and Gurami (O. goramy) fish thorns and scales in increasing salivary leukocyte and monocyte cells viability against Streptococcus mutans

2019 ◽  
Vol 52 (1) ◽  
pp. 45
Author(s):  
I Dewa Ayu Ratna Dewanti ◽  
I Dewa Ayu Susilawati ◽  
P. Purwanto ◽  
Pujiana Endah Lestari ◽  
Roedy Budirahardjo ◽  
...  
Keyword(s):  
Streptococcus Mutans ◽  
Microtiter Plate ◽  
Control Group ◽  
Fish Scales ◽  
Test Results ◽  
Omega 3 ◽  
Viability Analysis ◽  
Omega 6 ◽  
3 Omega

Background: Kuniran thorns and Gurami fish scales are rich in protein and minerals such as dentin believed to increase cell viability against Streptococcus mutans (S. mutans) that causes dental caries. These, in turn, can cause systemic diseases if left untreated. Purpose: This study aims to analyze the influence of Kuniran thorns and Gurami fishes scales on the viability of monocytes and salivary leukocytes against S. mutans. Methods: Monocytes and leukocytes salivary cells were placed on a microtiter plate and treated according to the nature of each group. This study comprised the following groups: control group: untreated; S. mutans group: induced by S. Mutans; Gurami thorn group: thorns + S. Mutans; Gurami scales group: scales + S. Mutans; Kuniran thorn group: thorns + S. Mutans; Kuniran scales group: scales + S. mutans. Viability analysis involved staining with Tripan Blue. Furthermore, the number of viable cells (white) was calculated under an inverted microscope at 200 times magnification from five fields of view. Data was analyzed by means of an ANOVA test followed by LSD test. Results: The ANOVA and LSD tests confirmed significant differences (0.01<P). Kuniran thorns and Gurami fish scales increased the viability of monocytes and salivary leukocytes, but not significantly. The content of flavonoids, amino acids, omega 3, omega 6 and antioxidants increased leukocyte metabolism, thereby increasing cell resistance to S. mutans infection. Conclusion: Kuniran thorns (U. moluccensis) and Gurami (O. goramy) fish scales increase the viability of salivary leukocyte and monocyte cells against Streptococcus mutans.

scholarly journals Characteristic Squalene compounds Shark Liver Oil of home industry product in Pelabuhan Ratu

2018 ◽  
Vol 20 (3) ◽  
pp. 494 ◽  
Author(s):  
Sri Ayu Insani ◽  
Sugeng Heri Suseno ◽  
Agoes Mardiono Jacoeb
Keyword(s):  
Fatty Acid ◽  
Fish Oil ◽  
Fatty Acid Profile ◽  
Test Results ◽  
Omega 3 ◽  
Shark Liver Oil ◽  
Omega 6 ◽  
3 Omega ◽  
Dominant Fatty Acid

Omega-3, Omega-6, Omega-9 fatty acids and Squalene are an active component of fish oil that are<br />beneficial to the human health. Squalene is countained in shark liver oil (Centrophorus sp.). The aim of<br />this research was to determine the quality and characterization of fish oil from of household production<br />at Pelabuhan Ratu. The analysis is the fatty acid profile, primer and sekunder oxidation and determine<br />the content of compounds squalene contained in the shark liver oil. The fatty acid profile showed that the<br />dominant fatty acid is oleic aced (28.22%). EPA and DHA of shark liver oil are 1.54% and 4.78% respectively.<br />The test results of parameter value of primary and secondary showed shark liver oil has a high oxidation<br />value of PV (17.73 mEg/kg), p-AV (29.32 mEg/kg), TOTOX (64.78 mEg/kg) and FFA (4.65%). The value<br />of the density and viscosity of the shark liver oil of 0.91 g/cm3 and 38.18 cPs. Clarity shark liver oil at a<br />wavelength of 450 nm is 84.98%. GC-MS showed that squalene peak appears at the retention time of 23.357<br />and 23.285 minutes with a total area of 12.49% and 22.14% for crude and pure (reffine) shark liver oil and<br />its molecular weight was 410.391 g/mol.<br /><br />

scholarly journals Possible Role of CYP450 Generated Omega-3/Omega-6 PUFA Metabolites in the Modulation of Blood Pressure and Vascular Function in Obese Children

Nutrients ◽  
2018 ◽  
Vol 10 (11) ◽  
pp. 1689 ◽  
Author(s):  
Sara Bonafini ◽  
Alice Giontella ◽  
Angela Tagetti ◽  
Denise Marcon ◽  
Martina Montagnana ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Vascular Function ◽  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
Lipid Mediator ◽  
Omega 3 ◽  
Obese Children ◽  
Omega 6 ◽  
3 Omega

Obesity is often accompanied by metabolic and haemodynamic disorders such as hypertension, even during childhood. Arachidonic acid (AA) is metabolized by cytochrome P450 (CYP450) enzymes to epoxyeicosatrienoic acids (EETs) and 20-hydroxyeicosatetraenoic acid (20-HETE), vasoactive and natriuretic metabolites that contribute to blood pressure (BP) regulation. Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) omega-3 polyunsaturated fatty acids may compete with AA for CYP450-dependent bioactive lipid mediator formation. We aimed at investigating the role of AA, EPA and DHA and their CYP450-dependent metabolites in BP control and vascular function in 66 overweight/obese children. Fatty acid profile moderately correlated with the corresponding CYP450-derived metabolites but their levels did not differ between children with normal BP (NBP) and high BP (HBP), except for higher EPA-derived epoxyeicosatetraenoic acids (EEQs) and their diols in HBP group, in which also the estimated CYP450-epoxygenase activity was higher. In the HBP group, EPA inversely correlated with BP, EEQs inversely correlated both with systolic BP and carotid Intima-Media Thickness (cIMT). The DHA-derived epoxydocosapentaenoic acids (EDPs) were inversely correlated with diastolic BP. Omega-3 derived epoxymetabolites appeared beneficially associated with BP and vascular structure/function only in obese children with HBP. Further investigations are needed to clarify the role of omega-3/omega-6 epoxymetabolites in children’s hemodynamics.

Teor e composição de lipídeos como ferramenta de gestão na nutrição de bovinos

2020 ◽  
Vol 9 (7) ◽  
pp. e334974037
Author(s):  
Graciele Araújo de Oliveira Caetano ◽  
Angela Aparecida da Fonseca ◽  
Cibelle Borges Figueiredo
Keyword(s):  
Omega 3 ◽  
Ácido Linoleico Conjugado ◽  
Omega 6 ◽  
3 Omega

Um fator diferencial na produção de bovinos é a compreensão da contribuição individual dos ácidos graxos e do papel dos lipídeos nos ruminantes, tanto na forma de análise (ácido graxo ou extrato etéreo), conceitos relacionados às características de ômega 3, ômega 6 e ácido linoleico conjugado na bio-hidrogenação, no metabolismo pós-absorção, bem como no conteúdo e composição dos ácidos graxos em relação à matéria seca dos alimentos. Sabe-se que diversos fatores podem afetar o teor, digestibilidade e degradabilidade das fibras presente na forragem, e o mesmo ocorre com os lipídeos. As diferenças entre os valores dos compostos presentes nos lipídeos podem ocorrer dependendo do ambiente, região do país ou fase de colheita e por isso, torna-se importante obter a análise da composição de ácidos graxos dos alimentos lipídicos, para que dessa maneira seja possível otimizar a utilização deste nutriente na dieta de animais ruminantes. Sendo assim, a proposta dessa revisão será trazer a discussão sobre o tema e abordar um entendimento sobre o conteúdo e composição de ácidos graxos dos ingredientes que compõem a dieta dos animais ruminantes, com ênfase na influência exercida no desempenho produtivo, imunonutrição, e no produto final (carne ou leite).

scholarly journals Creation of a database to assess effects of omega-3, omega-6 and total polyunsaturated fats on health: methodology for a set of systematic reviews

BMJ Open ◽  
2019 ◽  
Vol 9 (5) ◽  
pp. e029554 ◽  
Author(s):  
Lee Hooper ◽  
Asmaa Abdelhamid ◽  
Julii Brainard ◽  
Katherine H O Deane ◽  
Fujian Song
Keyword(s):  
Health Outcomes ◽  
Systematic Reviews ◽  
Sensitivity Analyses ◽  
Omega 3 ◽  
Alpha Linolenic Acid ◽  
Trial Duration ◽  
Omega 6 ◽  
3 Omega ◽  
Meta Analyses ◽  
Total Pufa

ObjectiveTo create a database of long-term randomised controlled trials (RCTs) comparing higher with lower omega-3, omega-6 or total polyunsaturated fatty acid (PUFA), regardless of reported outcomes, and to develop methods to assess effects of increasing omega-6, alpha-linolenic acid (ALA), long-chain omega-3 (LCn3) and total PUFA on health outcomes.DesignSystematic review search, methodology and meta-analyses.Data sourcesMedline, Embase, CENTRAL, WHO International Clinical Trials Registry Platform, Clinicaltrials.gov and trials in relevant systematic reviews.Eligibility criteriaRCTs of ≥24 weeks' duration assessing effects of increasing ALA, LCn3, omega-6 or total PUFAs, regardless of outcomes reported.Data synthesisMethods included random-effects meta-analyses and sensitivity analyses. Funnel plots were examined, and subgrouping assessed effects of intervention type, replacement, baseline diabetes risk and use of diabetic medications, trial duration and dose. Quality of evidence was assessed using Grading of Recommendations Assessment, Development and Evaluation (GRADE).ResultsElectronic searches generated 37 810 hits, de-duplicated to 19 772 titles and abstracts. We assessed 2155 full-text papers, conference abstracts and trials registry entries independently in duplicate. Included studies were grouped into 363 RCTs comparing higher with lower omega-3, omega-6 and/or total PUFA intake of at least 6 months’ duration—the Database.Of these 363 included RCTs, 216 RCTs were included in at least one of our reviews of health outcomes, data extracted and risk of bias assessed in duplicate. Ninety five RCTs were included in the Database but not included in our current reviews. Of these 311 completed trials, 27 altered ALA intake, 221 altered LCn3 intake and 16 trials altered omega-3 intake without specifying whether ALA or LCn3. Forty one trials altered omega-6 and 59 total PUFA.The remaining 52 trials are ongoing though 13 (25%) appear to be outstanding, or constitute missing data.ConclusionsThis extensive database of trials is available to allow assessment of further health outcomes.

scholarly journals The Fatty Acid Profile in Patients with Newly Diagnosed Diabetes: Why It Could Be Unsuspected

2017 ◽  
Vol 2017 ◽  
pp. 1-5 ◽  
Author(s):  
C. Castro-Correia ◽  
S. Sousa ◽  
S. Norberto ◽  
C. Matos ◽  
V. F. Domingues ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Control Group ◽  
Healthy Children ◽  
Omega 3 ◽  
Alpha Linolenic Acid ◽  
Diabetes Group ◽  
Diabetic Children ◽  
Omega 6 ◽  
Diagnosed Diabetes

Context. Several studies have shown a link between proinflammatory activity and the presence or deficit of some fatty acids. Inflammation is associated with several diseases including diabetes.Objective. To characterize and compare the fatty acids profiles in children with inaugural type 1 diabetes, diabetic children (at least 1 year after diagnosis), and healthy children.Design. Plasma fatty acids profiles in children with inaugural diabetes, children with noninaugural diabetes, and controls, all of whom were prepubescent with a BMI < 85th percentile, were evaluated.Results. Omega-3 fatty acid levels were higher in recently diagnosed subjects with diabetes than in controls. The ratio of omega-6/omega-3 fatty acids was higher in the control population. Omega-6 fatty acid levels were higher in the nonrecent diabetic subjects than in the children with recently diagnosed diabetes, and the levels were higher in the nonrecent diabetes group compared to the control group.Conclusion. Our findings showed higher levels of alpha-linolenic acid, EPA, and DHA, as well as mono- and polyunsaturated fatty acids, in diabetic children. These findings reinforce the importance of precocious nutritional attention and intervention in the treatment of diabetic children.

scholarly journals Effect of Different Ratio Omega-3 and Omega-6 in Total Mix Ration on Productive Performance, Blood Metabolites and Estrous Characteristic of Ewes

2018 ◽  
Vol 42 (4) ◽  
Author(s):  
Yusti Pujiawati ◽  
Lilis Khotijah ◽  
Asep Sudarman ◽  
Indah Wijayanti
Keyword(s):  
Blood Glucose ◽  
Blood Cholesterol ◽  
Daily Weight Gain ◽  
Blood Metabolites ◽  
Productive Performance ◽  
Omega 3 ◽  
Mating Period ◽  
Feed Efficiency Ratio ◽  
Omega 6 ◽  
3 Omega

This study was conducted to compare the effect of different ratio of omega-3:omega-6 in total mix ration to blood metabolites and reproductive performance of ewes. A total of 25 young ewes were randomly assigned to five experimental groups and five replications : R0 (without omega-3:omega-6), R1 (omega-3:omega-6 1:8), R2 (omega-3:omega-6 1:6), R3 (omega-3:omega-6 1:3), R4 (omega-3:omega-6 1:2). The parameters measured were feed intake, productive performance, blood glucose and cholesterol pre-mating period. Parameters of characteristic estrous measured were onset of estrous, length of estrous and estrous response. The result showed that ratio of omega-3 and omega-6 1:2 have a greatest daily weight gain and feed efficiency. Ratio of omega-3 and omega-6 1:2 have blood glucose lowest, but highest blood cholesterol. Addition of omega-3 cause to delays onset of estrous. The conclusion is greatest length of estrous, estrous response and pregnacy rate on ratio of omega-3 and omega-6 1:2 in ration.

scholarly journals Erythrocyte omega-3, omega-6 and trans fatty acids in relation to risk of preeclampsia among women delivering at harare maternity hospital, Zimbabwe

2007 ◽  
pp. 37-50
Author(s):  
K Mahomed ◽  
MA Williams ◽  
IB King ◽  
S Mudzamiri ◽  
GB Woelk
Keyword(s):  
Fatty Acids ◽  
Confidence Interval ◽  
Odds Ratio ◽  
Trans Fatty Acids ◽  
Positive Association ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Omega 6 ◽  
3 Omega ◽  
Risk Of Preeclampsia

We sought to examine the association between maternal erythrocyte omega-3, omega-6 and trans fatty acids and risk of preeclampsia. We conducted a case-control study of 170 women with proteinuric, pregnancy-induced hypertension and 185 normotensive pregnant women who delivered at Harare Maternity Hospital, Harare, Zimbabwe. We measured erythrocyte omega-3, omega-6 and trans fatty acid as the percentage of total fatty acids using gas chromatography. After multivariate adjustment for confounding factors, women in the highest quartile group for total omega-3 fatty acids compared with women in the lowest quartile experienced a 14% reduction in risk of preeclampsia (odds ratio 0.86, 95% confidence interval 0.45 to 1.63). For total omega-6 fatty acids the odds ratio was 0.46 (95% confidence interval 0.23 to 0.92), although there was suggestion of a slight increase in risk of preeclampsia associated with high levels of arachidonic acid. Among women in the highest quartile for arachidonic acid the odds ratio was 1.29 (95% confidence interval 0.66 to 2.54). A strong statistically significant positive association of diunsaturated fatty acids with a trans double bond with risk of preeclampsia was observed. Women in the upper quartile of 9-cis 12-trans octadecanoic acid (C(18:2n6ct)) compared with those in the lowest quartile experienced a 3-fold higher risk of preeclampsia (odds ratio = 3.02, 95% confidence interval 1.41 to 6.45). Among women in the highest quartile for 9-trans 12-cis octadecanoic acid (C(18:2n6tc)) the odds ratio was 3.32 (95% confidence interval 1.55 to 7.13). Monounsaturated trans fatty acids were also positively associated with the risk of preeclampsia, although of much reduced magnitude. We observed a strong positive association of trans fatty acids, particularly diunsaturated trans fatty acids, with the risk of preeclampsia. We found little support for the hypothesized inverse association between omega-3 fatty acids and preeclampsia risk in this population. Polyunsaturated fatty acids, particularly omega-3 fatty acids, were comparatively lower in Zimbabwean than among US pregnant women. Given the limited inter-person variation in omega-3 fatty acids among Zimbabwean women, our sample size may be too small to adequately assess the relation in this population.

scholarly journals Tu1753 Central Functions Altered by Chronic High-Lipids Diets Enriched With Omega-3, Omega-6 or Saturated Fat

2013 ◽  
Vol 144 (5) ◽  
pp. S-837 ◽  
Author(s):  
David Val-Laillet ◽  
Paul Meurice ◽  
Jean-Paul Lalles ◽  
Charles-Henri Malbert
Keyword(s):  
Saturated Fat ◽  
Omega 3 ◽  
Omega 6 ◽  
3 Omega

Topical application of omega-3-, omega-6-, and omega-9-rich oil emulsions for cutaneous wound healing in rats

2018 ◽  
Vol 9 (2) ◽  
pp. 418-433 ◽  
Author(s):  
Wan Maznah Wan Ishak ◽  
Haliza Katas ◽  
Ng Pei Yuen ◽  
Maizaton Atmadini Abdullah ◽  
Mohd Hanif Zulfakar
Keyword(s):  
Wound Healing ◽  
Topical Application ◽  
Cutaneous Wound Healing ◽  
Omega 3 ◽  
Cutaneous Wound ◽  
Omega 6 ◽  
3 Omega ◽  
Oil Emulsions

ANTICIPATORY ABILITY OF COACHES IN THE SYSTEM OF THEIR PROFESSIONAL COMPETENCE EVALUATION BY ATHLETES

2020 ◽  
Vol 8 (3) ◽  
pp. 103-111
Author(s):  
Lusine Stepanyan
Keyword(s):  
Work Experience ◽  
Personal Development ◽  
Professional Competence ◽  
Control Group ◽  
Test Results ◽  
Perceptual Evaluation ◽  
Competence Evaluation ◽  
The Subject ◽  
The Impact

Current research in psychology and psychophysiology focuses on the subject of anticipation and forecasting. Anticipatory sustainability is a personal trait that determines the ability to anticipate events and possible ways of personal development, as well as the ability to prevent interpersonal conflicts. The aim of the study was to identify the role of development level of anticipatory competence of coaches in their professional competence evaluation and perception by athletes. Research methods and organization. The research involved two groups of test subjects. The experimental group consisted of sport dance coaches and their students. The control group brought together experts in socionomic area with different work experience. We used testing and questionnaire methods to achieve the goal and objectives of the study. Testing method included the test for diagnosing anticipatory sustainability according to A. Mendelevich and the test of socio-perceptual coaching evaluation by athletes. We used the results of testing and questionnaires to provide a comparative and correlation analysis of data. Research results. The analysis of test results revealed the impact of work experience on the development of both spatial and temporal characteristics of the anticipation of coaches, indicating a possible effect on the intensity and direction of development of those characteristics in specific conditions. We have identified valid connections between the gnostic parameter (professional competence evaluation) of the socio-perceptual coaching evaluation by athletes and spatiotemporal characteristics of coaches' anticipation, defined as professionally important qualities of coaches. Moreover, we have demonstrated a weak direct relationship between the personality-situational component of the anticipatory sustainability of coaches and the emotional parameter of their socio-perceptual evaluation by athletes, indicating a significant role of communicative-anticipation sustainability in the development of an attitude of athletes to the coach. Conclusion. In summary, we can conclude that the anticipatory sustainability of coaches plays a key role in the structure of their competence, and the development of this property is possible under certain conditions.

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