scholarly journals Compounds from African Medicinal Plants with Activities against Protozoal Diseases: Schistosomiasis, Trypanosomiasis and Leishmaniasis

2018 ◽  
Author(s):  
Conrad V. Simoben ◽  
Fidele Ntie-Kang ◽  
Sergi H. Akone ◽  
Wolfgang Sippl
Keyword(s):  
Drug Discovery ◽  
Medicinal Plants ◽  
Drug Development ◽  
Leishmania Species ◽  
Global Scale ◽  
Parasitic Diseases ◽  
The World ◽  
Future Drug ◽  
Further Development ◽  
Micromolar Range

Parasitic diseases continue represent a threat on a global scale, particularly among the poorest countries in the world. This is particularly because of the absence of vaccines, and in some cases, resistance against available drugs, currently being used for their treatment. In this review emphasis is laid on natural products and scaffolds from African medicinal plants (AMPs) for lead drug discovery and possible further development of drugs for the treatment of parasitic diseases. In the discussion, emphasis has been laid on alkaloids, terpenoids, quinones, flavonoids and narrower compound classes of compounds with micromolar range activities against Schistosoma, Trypanosoma and Leishmania species. Suggestions for future drug development from African medicinal plants have also been provided.

scholarly journals Modernization of Ayurveda: A Brief Overview of Indian Initiatives

2014 ◽  
Vol 9 (2) ◽  
pp. 1934578X1400900
Author(s):  
Ambarish Mukherjee ◽  
Mousumi Banerjee ◽  
Vivekananda Mandal ◽  
Amritesh C. Shukla ◽  
Subhash C. Mandal
Keyword(s):  
Drug Discovery ◽  
Medicinal Plants ◽  
Traditional Medicine ◽  
Human Health ◽  
Traditional Knowledge ◽  
Allopathic Medicine ◽  
Medicinal Use ◽  
Crude Drugs ◽  
Local Traditions ◽  
Further Development

Ayurveda has been the main guiding force in drug discovery from traditional medicine. In concept, this system is rooted in folk or ethnomedicine and in practice it shows further refinement and development in accordance with local traditions. Isolation of active principles from crude drugs, their pharmacological evaluation, therapeutic proving and clinical application resulted in the genesis of modern or so called allopathic medicine. To keep the opportunity alive for further development in traditional as well as modern medicines, it is necessary to have an uninterrupted connection with ethnomedicine. Since the practice of ethnomedicine is based on the age-long indigenous knowledge which has been orally transmitted through generations and sustained in traditions there is an urgent need to document such knowledge. The ongoing strategies adopted in India to document the precious traditional knowledge and conserve medicinal plants are discussed in this communication. India with her rich plant wealth and traditional knowledge about the medicinal use of plants has tremendous scope to provide leadership in ensuring human health and longevity.

scholarly journals Dropshipping as a Modern Direction of Business Development in Ukraine

2020 ◽  
Vol 24 (1) ◽  
pp. 107-112
Author(s):  
T. Lunkina ◽  
◽  
A. Kuhlyar ◽  
Y. Kemova ◽  
◽  
...  
Keyword(s):  
Business Model ◽  
Capital Investment ◽  
Rapid Development ◽  
World Market ◽  
Global Scale ◽  
Business Development ◽  
Technical Process ◽  
The World ◽  
Further Development ◽  
Comparative Description

Annotation. Introduction. The economic crisis, the acceleration of the scientific and technical process are forcing young entrepreneurs to look for new ways to make a profit and save time. The sale of goods under this scheme is gaining popularity in Ukraine. We considered marketplace for the sale of goods under the drop shipping scheme Purpose. The purpose of this article is to determining the relevance and feasibility of this business model. Develop Ukrainian marketplaces and access Ukrainian products to the world market by placing advertisements on world search sites and introducing delivery from abroad. Results. The article explores the realities and identifies prospects for the development of drop shipping system in Ukraine. It is noted that drop shipping act as one of the popular business model. It was investigated advantages and disadvantage. It was created comparative description of drop shipping with the production of goods was made. Dropshipping is a good start for developing your own business and entering the world market. This type of business can be easily implemented both in Ukraine and in cooperation with other countries. The rapid development of technology gives impetus to the implementation of e-commerce through the sale of goods by the method of dropshipping around the world. An example of a world-famous platform for the sale of goods is considered Conclusion. Drop shipping is promising for starting your own business. It does not require significant capital investment. There is a possibility of further development in the field of product promotion. The sale of goods under the dropshipping system is promising for development on a global scale for domestic sites. The tool for realizing this perspective is to attract more foreign consumers and promote Ukrainian goods and brands. Keywords: drop shipping; manufacturer; implementation; operation; modernization; business.

Medicinal Plants and Their Role in Inflammation: A Close Look on Future Drug Discovery

2020 ◽  
pp. 137-158
Author(s):  
Gifty Sawhney ◽  
Satinder Kaur ◽  
Asha Bhagat ◽  
Zabeer Ahmed
Keyword(s):  
Drug Discovery ◽  
Medicinal Plants ◽  
Future Drug

scholarly journals A review on: Medicinal properties of ginkgo biloba

2021 ◽  
Vol 8 (3) ◽  
pp. 86-90
Author(s):  
Shoheb S Shaikh ◽  
Nachiket S Dighe
Keyword(s):  
Drug Discovery ◽  
Chemical Composition ◽  
Medicinal Plants ◽  
Traditional Medicine ◽  
Ginkgo Biloba ◽  
Modern Medicine ◽  
Current Paper ◽  
The World ◽  
Modern Chemical ◽  
Medicinal Properties

Traditional medicine and medicinal plants, as well as their study of modern chemical principles, may lead to the development of newer, less expensive medications. Ginkgo Biloba is well-known for curing a variety of ailments and is utilized in a variety of traditional medicinal formulations. Scientists and researchers from all over the world have spent decades studying the chemical composition of the entire Ginkgo Biloba plant, as well as its biological and pharmacological functions. These investigations established Ginkgo Biloba's medicinal potential in modern medicine and as a prospective drug discovery candidate. The current paper provides an overview of Ginkgo Bilobaethnobotany, phytochemistry, pharmacology, and toxicity.

scholarly journals Quinazoline pharmacophore in therapeutic medicine

2016 ◽  
Vol 11 (3) ◽  
pp. 716 ◽  
Author(s):  
Olayinka Oyewale Ajani ◽  
Damilola Victoria Aderohunmu ◽  
Ejike Nzube Umeokoro ◽  
Ayodele Ojo Olomieja
Keyword(s):  
Clinical Trials ◽  
Drug Discovery ◽  
Drug Design ◽  
Infectious Diseases ◽  
Drug Development ◽  
Molecular Targets ◽  
Beneficial Role ◽  
Future Drug ◽  
Broad Overview

<p>This present study comprehensively expatiates the functionalized utilization of quinazoline scaffolds in drug development and furnishes latest updates in pharmacological appositeness of its derivatives in order to reveal novel pathways for therapeutic targets. It traverses numerous biological potentials of quinazoline in the contemporary time to allow researchers’ unhindered access to the beneficial role of quinazoline in fighting infectious diseases for future drug discovery. This work provides broad overview of medicinal survey of quinazoline chemistry valuable in the discovery of more efficient clinical trials and to summarize the most promising molecular targets for drug design.  </p>

Drug Discovery and Development Strategies for COVID-19

2020 ◽  
Vol 2 (2) ◽  
pp. 1-5
Author(s):  
Aarajana Shrestha ◽  
Tara Man Kadayat
Keyword(s):  
Drug Discovery ◽  
Drug Development ◽  
Development Strategies ◽  
Special Issue ◽  
Medical Sciences ◽  
Drug Discovery And Development ◽  
Current Drug ◽  
The World ◽  
Global Threat ◽  
Effective Drugs

COVID-19 Special Issue: Coronavirus Disease 2019 (COVID-19) has emerged as a global threat. Scientists and clinicians are endeavoring to find effective drugs and vaccines for this disease. This special issue of the Europasian Journal of Medical Sciences (EJMS) aims to cover the problems, solutions, and challenges of COVID-19 around the world. In this Editorial, EJMS Editors Aarajana Shrestha and Tara Man Kadayat highlight the processes of drug discovery and development and a brief overview of the current drug development strategies against COVID-19.

scholarly journals Argentinean’s Plants with Interest in Ethnomedicine as Wormers

2016 ◽  
Vol 5 ◽  
pp. 1-17
Author(s):  
Griselda Haag ◽  
Gustavo Horacio Marin ◽  
Jorge Errecalde
Keyword(s):  
Drug Development ◽  
Agricultural Science ◽  
Medical Sciences ◽  
Active Ingredients ◽  
Popular Medicine ◽  
Scientific Support ◽  
Online Databases ◽  
Natural Treatment ◽  
The World ◽  
Future Drug

Plants are different all over the world and its indications change according to the country they are located. This paper is developed in order to perform a comprehensive literature´s review about plants used as anti-parasitic either in traditional or popular medicine in Argentina, and to provide a scientific support for their use in this medical indication. All Ethnobotany, Ethnomedicine, Phytomedicine books from Libraries of the Faculty of Exact Sciences Faculty of Medical Sciences, Agricultural Science, from all National Universities in Argentina were included in the study. Herbal characteristics and therapies were searched in online databases such as Medline PubMed, Science Direct and Scopus. The results obtained show the potential of Ethnomedicine in Argentina as a source of active ingredients for phytotherapy, providing data about species for anti-parasitic treatment. Thus, we found many Argentinean’s plants with anti-parasitic properties which might be considered alternatives for natural treatment or future drug development against wormers.

Screening and evaluation of Terminalia catappa and its compound application

2020 ◽  
Vol 10 (4) ◽  
pp. 89-92
Author(s):  
Sravani G ◽  
Linga Naik A ◽  
Kranthi A ◽  
Priyanka G
Keyword(s):  
Medicinal Plants ◽  
Conventional Therapy ◽  
Significant Aspect ◽  
Terminalia Catappa ◽  
Specific Disease ◽  
Common Item ◽  
Conventional Medication ◽  
The World ◽  
Enormous Number

Plant determined medications remains an important source, particularly in creating countries, to look at genuine sicknesses roughly 62-80% of the total populace although everything depends on conventional medication for the therapy of specific disease. Indeed, plants produce a various scope of bioactive atoms creation them an ironic wellspring of an alternate kind of drugs. There are hardly any reports and utilization of plants in conventional mending by either ancestral individuals or indigenous network. Rejuvenating plants are the wellspring of extraordinary monetary estimation of everywhere on over the world. Nature has the best word on us a rich plant riches, and an enormous number of assorted kinds of plants develop in various pieces of the nation. Homegrown medication is as yet a pillar of around 75 to 85% the entire populace and the significant aspect of the conventional therapy the utilization of the plant extricate and the dynamic constituents. Among the 7000 types of rejuvenating plants perceived everywhere on over the world in excess of 9000, valuable medicinal plants are found in India. Unfortunately, just not many of them are utilized for their therapeutic worth. Around 1500 plants systematically utilize the conventional arrangement of Indian medication. Notwithstanding, the ethanopharmacologist, microbiologist, botanist and common item physicist world over today, is continually still looking for therapeutic adequacy of the plants on the phytochemicals. Along these lines, the quest for the new phytochemical is the foremost significant important to research the primer phytochemical examination to Terminalia catappa and Syzygium jumbolanam.

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