scholarly journals Plasma Level’s of Neuregulin-1 in Healthy People

2022 ◽  
Vol 17 (6) ◽  
pp. 853-859
Author(s):  
K. A. Zhbanov ◽  
A. A. Shchendrygina ◽  
E. A. Zheleznykh ◽  
E. V. Privalova ◽  
A. Y. Suvorov ◽  
...  

Aim. To determine the median levels of neuregulin-1 (NRG-1; endothelium-derived growth factor and the natural agonist of the ERBB3 and ERBB4 receptors) NRG-1 in healthy volunteers and to study the associations of NRG-1 levels with gender and age.Material and Methods. Ninety seven healthy participants were enrolled (median age of 44 [32-54], men 45 men [46.4%]). The following age groups were identified: 20-29 y.о. (n=20, men – 50.0%),  30-39  y.о.  (n=21,  men  –  52.4%),  40-49  y.о.  (n=22,  men  –  45.5%),  50-59  y.о. (n=22, men – 36.4%); 60-69 y.о. (n=12, men – 50.0%). Peripheral blood samples were collected at the time of enrolment, standard laboratory tests were performed, and NRG-1 levels were determined in the plasma samples by ELISA.Results. In the cohort of 97 healthy participants the median value of NRG-1 was 0.3 [0.121-2.24] ng/ml. NRG-1 levels did not differ significantly between men and women (p=0.145), indicating that NRG-1 levels are not influenced by gender. The levels of NRG-1 were similar in the different age groups: age 20-29 years=0.26 [0.17-0.37] ng/ml; age 30-39=0.24 [0.1-0.39] ng/ml; age 40-49=0.31 [0.19-1.15] ng/ml; age 50-59=0.37  [0.19-1.0] ng/ml; age 60-69=0.4 [0.13-0.81] ng/ml. Correlation analysis between NRG-1 levels and route blood measurements (haemoglobin, lipids, glucose, creatinine, and uretic acid) did not show significant associations.Conclusions. In this study, the median value of NRG-1 plasma levels were determined. The results of the study show that age and gender had no influence on NRG-1 values.

1996 ◽  
Vol 13 (3) ◽  
pp. 274-287 ◽  
Author(s):  
Markus Lamprecht ◽  
Hanspeter Stamm

Under the influence of the Sport for All movement the sport system in Switzerland has changed. Sport has become a leisure-time activity for an increasing number of people and has gained new meanings and forms. Many traditional limitations to participation appear to have been removed. By focusing on gender and age, this study, based on a survey of 1,103 employees, explores the extent to which particularisms and inequalities in contemporary recreational Swiss sport still exist. Although the involvement in sport by men and women, and involvement of different age groups, are quite similar in terms of frequency, their forms and meanings remain different. Using correspondence analysis we identify different sports fields and different sporting patterns by gender and age in terms of motives, places, and activities.


2011 ◽  
Vol 33 (4) ◽  
pp. 367-373 ◽  
Author(s):  
Cynthia C Wolle ◽  
Marcos Sanches ◽  
Monica L Zilberman ◽  
Raul Caetano ◽  
Marcos Zaleski ◽  
...  

OBJECTIVE: To examine sex differences in alcohol consumption according to age groups, and to assess gender and age effects on several aspects of alcohol consumption patterns. METHOD: Based on a Brazilian nationwide representative sample (n = 3,007), we analysed the differences in drinking patterns between genders. We also assessed the effects of gender, age, and gender by age interaction for alcohol consumption dimensions (frequent drinking, usual intake, binge drinking, and frequent binge drinking), using logistic and negative binomial regression models. RESULTS: Gender, age, and gender by age interaction had significant effects on the predictive models for all studied drinking patterns, except for the 'usual' dosage. The effect of gender on drinking patterns varies with age. While gender has a greater effect in older age groups, the difference between men and women decreased in the younger age groups. CONCLUSIONS: Gender convergence regarding alcohol use is a trend that might be influenced by environmental factors and should be addressed in prevention and treatment programs, as well as in public health policies.


2013 ◽  
Vol 26 (1) ◽  
pp. 135-145 ◽  
Author(s):  
Kerry A. Sargent-Cox ◽  
Masori Rippon ◽  
Richard A. Burns

ABSTRACTBackground:The development of instruments to measure aging attitudes is an essential part of research into the role of individual differences in the aging process, giving clarification to the relationship between attitudes and behavior across the lifespan. Here we test the structural validity of Lasher and Faulkender's (1993) Anxiety about Aging Scale (AAS), and explore measurement invariance across age and gender.Methods:A sample of 783 adults (42% females) age ranging from 20 to 97 years (M = 57.3, SD = 13.66) participated.Results:The first-order four-factor AAS model reflecting the original Lasher and Faulkender (1993) structure showed a better fit to the data than the second-order model. Measurement invariance for both gender and age groups (young adults 20–44 years; mid-aged adults 45–64 years, older adults 65+ years old) was found for three of the factors, but not for all items in the Fear of Losses factor. Structural covariance inequality between the Fear of Losses and Physical Appearance factors was shown between males and females.Conclusions:Findings indicate that the original AAS measures four distinct dimensions of anxiety about aging. These dimensions were shown to be generally comparable across age and gender, indicating that the AAS is a suitable measure for providing meaningful comparison of anxiety about aging across the lifespan. The exception is the Fear of Losses factor, where items may have differential meanings across groups based on cultural and social attitudes regarding aging and gender.


2019 ◽  
Vol 9 (1) ◽  
pp. 33
Author(s):  
Nasim Shams ◽  
Mahshid Razavi ◽  
Azar Mehrabi ◽  
Sina Salehin ◽  
Parisa Sarikhani

Introduction: this study aimed at determining gender and age by mandibular anatomy landmarks in computed tomography with Cone-Beam (CBCT). Methodology: this cross sectional study was performed on 147 CBCT images available in archive of radiology in the dentistry department of Ahvaz Jondi Shapoor medical science university. In this research, we assessed parameters including SMEF: Distance from mental foramen to the highest point of alveolar crest ridge, BIAC: distance from lowest point of IAC to the most anterior tangent point of buccal mandibular plate, LIAC: distance from the lowest IAC point to the most posterior tangent point o mandibular lingual plate, IMEF: distance from the lowest mental hole border to the lowest tangent point on inferior mandibular border, D2: distance from the lowest IAC canal border to the lowest tangent point on inferior mandibular border and gonial angle: junction of inferior mandibular border and posterior ramus border. Data were analysed by SPSS software 20th version and Spearman correlation coefficient tests, one-way variance analysis, Kruskal-Wallis, independent t, and Uman Withney. Results: SMEF level was significantly different in groups and in 25-34 group it was significantly higher than under 25 group. In right side it was significantly higher than female. IMEF had no significant difference in age groups and in both side it was higher in male than female. BIAC in both sides had no significant difference. LIAC in both sides an in different ages had no significant difference in male and female. D2 had no significant difference in both sides. But in a group with patients older than 55 it was significantly higher than 45-54 group. In addition, in left side it was higher in male than female there was no significant difference in gonial angle in different groups in left side with in right side there was significant difference in different age groups. But there was no significant difference in gender. Conclusion: evaluated indices in this research are not ry accurate to forecast age and gender and they cannot be used as accurate tools in estimating age and gender of people.


2021 ◽  
Vol 15 (11) ◽  
pp. 3325-3328
Author(s):  
Zarife Taştan

Background: It has been a matter of curiosity by athletes, coaches, sports commentators, and sports psychologists why certain athletes are the world's best in their field. Aim: In our study, the mental toughness and motivational climates of licensed basketball players were examined according to age and gender variables. Methods: In this study, the relational screening model was used to determine the relationship between mental toughness and motivational climate in licensed basketball players studying in physical education and sports teaching departments. Results: As a result of this study, where mental toughness and motivational climate, which are known to be necessary to maintain the ideal performance level during competition, are evaluated according to age and gender variables, it is seen that the motivational climate and mental toughness scores do not differ according to the gender of the athletes. Conclusion: As a result of this study, where mental toughness and motivational climate, which are known to be necessary to maintain the ideal performance level during competition, are evaluated according to age and gender variables, it is seen that the motivational climate and mental toughness scores do not differ according to the gender of the athletes. Keywords: Mastery Climate, Performance Climate, Mental Toughness, Age, Gender


2020 ◽  
Vol 12 (2) ◽  
pp. 70-79
Author(s):  
FlávioAlberto Oliva ◽  
Maria Lúcia Ribeiro ◽  
Marina Armelin Silva ◽  
Marjori Leiva Camparoto ◽  
Telma Reginato Martins

The goal of this study was to understand the gender and age profile of the users of ambulatory services at public hospital. Gender and age are fundamental elements for the construction of public policies at local and regional level. We performed a 3-year retrospective data collection, regarding age and gender of the population of the outpatient clinic of the public hospital between 2013 and 2015. It is a research with quantitative approach performed through three databases from january 2013 to December 2015 totaling 460.505 consultations. The database of the public hospital was adopted as the primary source, it was also consulted the database of the last two censuses of the Brazilian Institute of Geography and Statistics (IBGE) and the database of the Regional Health Division. The cross-checking of data, through Microsoft Excel and the Online Analytical Processing (OLAP) software, allowed the construction of a graph structured by gender and age according to the standards defined by IBGE on 2010, as well as the comparison between age and gender profile of the total population attended by public hospital and its consultations. The female audience represents 60.5% of the attendances, while the male population accounts for 39.5%. Only in the age groups between 0 and 14 and 85 to 89 years the male audience is larger. The difference in care is accentuated in the middle of the pyramid, in the ranges between 30 and 69 years, during which time women are responsible for 65.5% of the attendances against 34.5% of men. Such gender proportional differences are maintained on the total population, the only significant variation is on the age group from 80 and older where although there is a female majority of users, there is also a larger female majority on the population. Studies show that women make more references to health problems than men, as these represent, according to the male imagination, virility and strength, not representing vulnerability to the disease. Men do not recognize themselves as targets of health care and they are less likely to seek health services for cultural reasons, mainly, opening space for discussion about social inequalities in health between men and women.


2021 ◽  
Vol 7 (2) ◽  
Author(s):  
Veronika Makarova

Abstract This paper focuses on the Iranian taaroff politeness system. We report a quantitative analysis of the attitudes to taaroff held by 60 Iranians (30 women and 30 men) of two age groups (20–29 and 40–59 years old) and their use of formulaic taaroff expressions in conversations. The data come from dialogues elicited from the participants in Iran via short scripted scenarios and from their answers to a questionnaire survey about their attitudes to taaroff. Taaroff expressions were manually extracted from the dialogue transcripts and their overall use as well as frequencies of each expression were compared across the gender and age groups with the help of t-tests. The participants’ answers to the survey questions were compared across the groups with Kruskal-Wallis H tests. The results show statistically significant differences in the participants’ attitudes to taaroff and in its use in dialogues by gender and age group.


Stroke ◽  
2013 ◽  
Vol 44 (suppl_1) ◽  
Author(s):  
Jane C Khoury ◽  
Brett Kissela ◽  
Heidi Sucharew ◽  
Kathleen Alwell ◽  
Charles Moomaw ◽  
...  

Background: A surge of midlife (age 55-64 years) stroke in women, and not in men, has previously been reported using prevalence data from NHANES. However it is not clear if this same finding would be seen within age- and gender-specific incidence rates of stroke. We sought to examine the incidence of ischemic (IS) stroke and the gender-specific trends over time in a population-based study of stroke epidemiology. Methods: Data from the population-based Greater Cincinnati and Northern Kentucky epidemiology of stroke study for adults (≥ 20 years) was used from three collection periods; 7/1993 to 6/1994, 1999, and 2005. We compared the IS stroke incidence rates in women versus men between the three study periods, in particular for the ages 35 to 65 years. Sex specific age, and race adjusted incidence rates and race adjusted, age and gender specific incidence rates were estimated and adjusted to the 2000 US population. Results: A total of 5166 incident IS strokes were identified: 1709 from 7/1993 to 6/1994, 1778 from 1999, and 1679 from 2005. These were 56% female, 18% black; mean age was 71.4 (13.7) years. Overall, IS stroke incidence declined in both women and men in 2005 compared to the previous time periods (p<0.01). However, there was a significant increase over time in stroke incidence seen in both men and women in the younger age groups in 2005, compared with 1993/94 (p<0.05). Conclusions: We found that stroke incidence is not changing differently over time for men and women. There has been an increase in IS stroke incidence in the young, but this is found in both men and women. The previously reported “surge” in middle-aged stroke prevalence may be related in part to increased rates of stroke in the young, with survival to middle-age, but our incidence findings do not explain the reported difference in prevalence found between women and men in the NHANES cohort.


2019 ◽  
Vol 23 (2) ◽  
pp. 197-202
Author(s):  
R. M. Radzhabkadiev ◽  
V. C. Evstratova ◽  
K. V. Vybornaya ◽  
R. A. Khanferyan

The article contains the results of a survey of 11,850 persons of both sexes in eight Federal Districts of the Russian Federation. The survey was conducted on the following age groups of men and women: 12-17, 18-30, 31-45 and 46-60 years. In each group of subjects, the number of questionnaires was at least 150 persons of each sex. When comparing the consumption of macronutrients in different federal districts, it is established that there are insignificant age and gender differences in the level of their consumption. Studies have shown that the intake of proteins and carbohydrates is within the recommended consumption rates, and the fat component has been increased in the population of all federal districts of Russia.


2017 ◽  
Vol 27 (1) ◽  
pp. 97-113 ◽  
Author(s):  
Andrei Ion ◽  
Christopher D. Nye ◽  
Dragoş Iliescu

Gender- and age-related differences in the variability of various human attributes and abilities have been investigated. This article investigates the age and gender differences in the variability of Holland’s six vocational dimensions with a sample including 1,519 participants, divided into four age groups: early adolescence (12–15 years old), adolescence (16–20 years old), young adulthood (21–30 years old), and adulthood (31–59 years old). The results showed nontrivial differences in the variability of vocational interests across gender and age groups alike. Although significant differences in variability were observed for all vocational interest dimensions except investigative, the most pronounced differences in variability across age and gender were observed for realistic and conventional dimensions. Generally, the observed differences in variability were larger in adolescence than in adulthood. Overall, vocational interests displayed less differentiation within the younger age groups (early adolescence and early adulthood) as compared to adulthood.


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