scholarly journals Development a System for Modeling and Assessing the Hazard of the Works in Medical and Biological Facilities

2008 ◽  
pp. 15-19
Author(s):  
I. N. Yezhov ◽  
Yu. I. Yashechkin ◽  
M. N. Lyapin ◽  
I. G. Drozdov
Keyword(s):  
Biological Agents ◽  
Risk Theory ◽  
Potential Danger ◽  
Practical Application ◽  
Biological Profile ◽  
Biological Safety ◽  
Analytical Review ◽  
Complex Well

Within the frames of an analytical review, modern approaches are described whose development is considered to be very important in order to rationally operate secure working procedures at the facilities of medical and biological profile. Peculiarities of formulating the methods to assess biological hazards are analyzed together with the ways of their objectivization. The place and the role of biological safety as a scientific trend are discussed in relation with the problem of availability of practical application of the "risk theory" elements with the aim of making governing decisions based on complex, well established estimations. The architecture of the system of modeling and estimation of potential danger associated with handling pathogenic biological agents is enunciated.

scholarly journals The Role of Peptides in the Design of Electrochemical Biosensors for Clinical Diagnostics

Biosensors ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 246
Author(s):  
Patrick Severin Sfragano ◽  
Giulia Moro ◽  
Federico Polo ◽  
Ilaria Palchetti
Keyword(s):  
Functional Groups ◽  
Synthetic Peptides ◽  
Clinical Diagnostics ◽  
Electrochemical Biosensors ◽  
Practical Application ◽  
Design And Development ◽  
Electrode Surfaces ◽  
Electrochemical Transducers ◽  
Target Analyte

Peptides represent a promising class of biorecognition elements that can be coupled to electrochemical transducers. The benefits lie mainly in their stability and selectivity toward a target analyte. Furthermore, they can be synthesized rather easily and modified with specific functional groups, thus making them suitable for the development of novel architectures for biosensing platforms, as well as alternative labelling tools. Peptides have also been proposed as antibiofouling agents. Indeed, biofouling caused by the accumulation of biomolecules on electrode surfaces is one of the major issues and challenges to be addressed in the practical application of electrochemical biosensors. In this review, we summarise trends from the last three years in the design and development of electrochemical biosensors using synthetic peptides. The different roles of peptides in the design of electrochemical biosensors are described. The main procedures of selection and synthesis are discussed. Selected applications in clinical diagnostics are also described.

So far and yet so near: The emerging characteristics, forms and configurations of organizational proximity in the context of digitalization

2021 ◽  
pp. 1-16
Author(s):  
Hongxia Peng
Keyword(s):  
Conceptual Framework ◽  
Crucial Role ◽  
Organizational Context ◽  
Organizational Studies ◽  
Cognitive Approach ◽  
Analytical Review ◽  
Organizational Proximity ◽  
Conceptual Study ◽  
Management Cognition

BACKGROUND: The current pandemic crisis evidences the importance of questioning and reconsidering the evolution of organizational proximity and the crucial role of digitalization in the emergence of new characteristics, forms and configurations of organizational proximity. OBJECTIVE: This article presents a conceptual study aimed at analyzing the evolution of organizational proximity in the context of digitalization. METHODS: Adopting a systemic-cognitive approach inspired by existing studies on management cognition and the biology of cognition, this article first presents an analytical review of existing research in organizational studies and proposes a taxonomy of proximity based on the forms and characteristics identified in the organizational context. Second, it introduces the notion of a proximity unit, based on which a conceptual framework for analyzing organizational proximity is conceived. RESULTS: Based on the proposed framework, this article analyzes the new characteristics and forms of organizational proximity and identifies possible configurations of organizational proximity by pointing out the emergence of substituted proximity propelled by digitalization and formulating six propositions. CONCLUSIONS: The article ends by arguing that it is important for organizations to conceive a composite proximity strategy by taking into account the effect of substituted proximity, driven by digitalization, in the configuration of organizational proximity.

scholarly journals All-Russian Library Congress — 2018: On the Way to Creation of the Librarianship Development Concept

2018 ◽  
Vol 67 (3) ◽  
pp. 247-256 ◽  
Author(s):  
I. A. Trushina ◽  
V. V. Meshcheryakova
Keyword(s):  
Russian Federation ◽  
Information Technologies ◽  
Public Libraries ◽  
Goods And Services ◽  
Special Events ◽  
New Information ◽  
Analytical Review ◽  
Open Discussion ◽  
The Russian Federation

he article presents an analytical review of the All-Russian Library Congress, held in Vladimir — the Library Capital of Russia 2018 — on 12—18 May 2018. The Congress was devoted to the theme “Ba-sing on the Past, We Build the Future. The Role of Cultural Heritage in Transforming the Librarianship in Russia”. The Congress held an open Discussion on the concept of librarianship development in the Russian Federation; it adopted the Guidelines on local lore activities for public libraries of the Russian Federation and approved the Regulations on the Council for Professional Qualifications in the Field of Library and Information Activities, planned for creation under the Russian Library Association. The Congress worked in various formats: pre-session events, plenary sessions, section meetings by library types and activity areas, and special events. The 19th Exhibition of Publishing Products, New Information Technologies, Goods and Services complemented the Congress. The Congress determined Tula to be the Library Capital of Russia 2019.

scholarly journals Complex interactions in legume/cereal intercropping system: role of root exudates in root-to-root communication

2017 ◽  
Author(s):  
Yinshan Jiao ◽  
Entao Wang ◽  
Wenfeng Chen ◽  
Donald L. Smith
Keyword(s):  
Nitrogen Fixation ◽  
Root Exudates ◽  
Faba Bean ◽  
The Novel ◽  
Practical Application ◽  
Corn Root ◽  
Complex Interactions ◽  
Root Interactions ◽  
Ecological Principles

Dear Editor,Legume/cereal intercropping systems have been regarded as the practical application of basic ecological principles such as diversity, competition and facilitation. In a recent PNAS paper, Li et al. (1) describe the novel finding that maize exudates promote faba bean nodulation and nitrogen fixation by upregulating genes involved in (iso)flavonoids synthesis (chalcone–flavanone isomerase) within faba bean, resulting in production of more genistein, a legume-to-rhizobia signal during establishment of the faba bean N2–fixing symbiosis. Although we salute the authors’ methodological efforts, there is another mechanism that could be responsible for the effect of corn root exudates on faba been nitrogen fixation observed in this article (1). The authors may misunderstand their data and the signalling role of maize exudates, thus got a defective model for the root interactions between faba bean and maize.

scholarly journals Severe eosinophilic bronchial asthma: new therapeutic options

2018 ◽  
pp. 44-52 ◽  
Author(s):  
N. M. Nenasheva
Keyword(s):  
Monoclonal Antibodies ◽  
Severe Asthma ◽  
Bronchial Asthma ◽  
Biological Agents ◽  
Therapeutic Options ◽  
Clinical Use ◽  
Eosinophilic Asthma ◽  
Interleukin 5 ◽  
Severe Eosinophilic Asthma

Eosinophilic asthma is a common phenotype of severe asthma, occurring in at least half of patients. In recent years, there have been significant changes in the approaches to the treatment of severe bronchial asthma and, above all, eosinophilic asthma. The article discusses the role of eosinophils in the pathogenesis of severe asthma, the detection of the phenotype of severe eosinophilic asthma, and modern approaches to targeting severe asthma with an eosinophilic phenotype using biological agents. A special emphasis is placed on preparations of monoclonal antibodies to interleukin-5, in particular, mepolizumab, recently approved for clinical use in our country.

scholarly journals The use of analytical procedures by Yemeni auditors

2015 ◽  
Vol 12 (2) ◽  
pp. 17-25
Author(s):  
Shamharir Abidin ◽  
Mohammed Abobaker Baabbad
Keyword(s):  
Financial Statements ◽  
Audit Firms ◽  
Analytical Review ◽  
Analytical Procedures

This study sets out to investigate the extent to which Yemeni auditors use analytical review procedures during the audit of client’s financial statements. It also examines the stage of auditing procedure in which Yemeni auditors implement analytical review procedures. Moreover, the study determines the relationships between the importance’s factors and the use of analytical review procedures. The findings of the study have indicated that the Analytical Procedures were utilized on high percentage by audits in larger and high experienced audit firms compared to small and low experienced audit firms where the results have shown low percentage. Nevertheless, the role of auditors’ perception towards Analytical Procedures has proved to have a significant effect of usage of Analytical Procedures

scholarly journals PLOT ELEMENTS AND MOTIVES OF THE NOVEL “CHEVENGUR” IN PLATONOV’S SHORT STORY “POTUDAN RIVER”

2021 ◽  
Vol 26 (1) ◽  
pp. 44-55
Author(s):  
N. Mikhaylovna Malygina ◽  
Keyword(s):  
Short Story ◽  
The Novel ◽  
Love Story ◽  
Planetary Scale ◽  
The Family ◽  
Analytical Review ◽  
Eugene Onegin ◽  
Intertextual Connections ◽  
First Time

The relevance of the article is determined by the researcher of the semantic poetics of Platonov’s story “Potudan River”. We carry out an analytical review of the lifetime criticism and articles of modern researchers about the story, on the basis of which we formulate the purpose of the study, due to the need for a new approach to the interpretation of the work and the identification of the principles of its poetics. The novelty of the article is determined by the identification of the multilayered symbolism of the title of the story, which allows to establish the insufficiency of the conclusions that the content of the “Potudan River” is limited to the family theme. At the level of micropoetics we reveal symbolic details that connect the content of the story with the motive of love for the distant, medical and construction subjects and revealing the planetary scale of the author’s thinking. For the first time, it was established that Platonov’s story “Potudan River” was written based on part of the plot of the novel “Chevengur” – the love story of Alexander Dvanov and Sonya Mandrova. We show that the heroes of the story “Potudan River” Nikita Firsov, Lyuba Kuznetsova and Nikita’s father are doubles of the characters in the novel “Chevengur” by Sasha Dvanov, Sonya Mandrova, and Zakhar Pavlovich. The connection of the image of Lyuba with the archetype of the bride is considered. The paper reveals for the first time the intertextual connections of the story “Potudan River” with the poem “The Bronze Horseman” and the novel in verse “Eugene Onegin” by A. Pushkin, in the texts of which the writer found material for modeling the ordinary fate of the hero. Multi-level connections of the content of the story “Potudan River” with Platonov’s artistic world, which is a complete metatext, are found, which opens up new opportunities for determining the role of the editing technique and the principles of returning to the plots and motives of the works of the 1920s, as well as their transformation in the writer’s work of the 1930s.

scholarly journals THE PROBLEM OF RESILIENCE OF THE PERSONALITY TO DIFFICULT LIFE SITUATIONS IN THE EDUCATIONAL ENVIRONMENT IN THE RUSSIAN AND FOREIGN RESEARCH

2019 ◽  
Vol 7 (1) ◽  
pp. 11
Author(s):  
N. I. Dunaeva ◽  
H. E. Serebrovsky ◽  
P. A. Egorova
Keyword(s):  
Psychological Research ◽  
Educational Environment ◽  
Difficult Situation ◽  
Main Method ◽  
Factors Influencing ◽  
Psychological Structure ◽  
Analytical Review ◽  
Psychological Knowledge ◽  
Definition Of

Introduction: in article the problem of psychology of resilience of the personality to difficult life situations, identifications of the factors contributing to the development of resilience of the personality is discussed. Today in psychological literature there is still a lack of researches of resilience of the personality, the factors, such as the external and internal ones, the factors influencing the development of person’s resilience are insufficiently studied. An important point in understanding of formation of mechanisms of resilience of the personality is studying of a role of the educational environment as a factor of resilience of the personality to difficult life situations. In this regard it becomes necessary to generalize the saved-up material in works of the Russian and foreign researchers on a problem of influence of the educational environment as a factor of resilience of the personality to difficult life situations. The results of foreign researchers on the problem of studying of influence of specially organized safe educational environment on the resilience of the personality to difficult life situations are presented in the article. Materials and methods: the article is an analytical review where the attempt of systematization of scientific psychological knowledge of a problem of psychology of resilience of the personality to difficult life situations is made. The main method of studying of resilience of the personality to negative life situations in the conditions of the educational environment is the method of the theoretical analysis of scientific psychological foreign and domestic sources. Subjective approach is the methodological basis for studying of resilience of the personality to difficult life situations. Results of a research: consideration of theoretical provisions of resilience of the personality and empirical researches of foreign authors of influence of the educational environment on the resilience of the personality to difficult life situations in the context of researches of psychology of safety, subject approach, the intra-resources and Inter resources helping to cope with a difficult situation. The authors offer a definition of resilience of the personality in the course of exiting from difficult life situations. The scientific proof of the importance of formation of safe, subjective and positive educational environment when developing resilience of the personality to difficult life situations is consistently provided. Discussion and conclusions: the conclusion about undoubted relevance of the questions connected with a research of resilience of the personality to difficult life situations and existence of foreign psychological researches on this issue is proved. Taking into consideration the results of scarce psychological research carried out by domestic and foreign authors the need for further studying of psychological structure of resilience of the personality to difficult life situations and also factors and conditions of its formation is proved. At the same time the significance and the importance of formation of safe, subject and positive educational environment in development of resilience of the personality to difficult life situations is emphasized.

scholarly journals N.V. Gogol’s Works and Censorship

Literary Fact ◽  
2021 ◽  
pp. 238-256
Author(s):  
Igor A. Vinogradov
Keyword(s):  
Literary Criticism ◽  
Good Reason ◽  
Evidence Based ◽  
Previous Period ◽  
Analytical Review ◽  
Negative Role ◽  
The Common ◽  
The Government ◽  
First Time

For the first time, an analytical review of all, without exception, censorship stories of N.V. Gogol’s works is presented. An objective picture of Gogol's relationship with the censorship is being recreated. The findings of the study allow, with good reason, to judge about the interference of censors in the writer's works in a fundamentally different way, in comparison with the ideas offered by literary criticism of the previous period without solid evidence. Based on a thorough analysis, involving numerous archival sources, the common, stereotypical opinions about the extremely negative role of censorship in Gogol’s fate are being revised. The most significant negative result among all censorship interventions in Gogol's works was the activity of the censor of Westernizing views, opposed to the government, a professor at St. Petersburg University, A.V. Nikitenko. It is the numerous reductions of Nikitenko, И.А. Виноградов. Произведения Н .В. Гоголя и цензура 255 a friend of V.G. Belinsky, in Gogol's religious and patriotic book “Selected Passages from Correspondence with Friends” that the writer called “censorship murder”. No less significant was the intervention of the liberal censor in the texts of “Dead Souls”, “Theatrical Travel after the Presentation of a New Comedy” and other works of the writer. It is concluded that, with the exception of this “intrigue” against Gogol by the censor Nikitenko, on the whole Gogol's texts encountered relatively insignificant difficulties in censorship.

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