Rare Complications of VP Shunt Surgery Resulting in Significant Morbidity and Mortality: Report of Four Cases and Review of the Literature

Atrial fibrillation (AF) is the most common arrhythmia worldwide and is associated with significant morbidity and mortality. A number of risk factors have been associated with AF, though few studies have explored the association between gastrointestinal and liver diseases and AF. Additionally, AF and treatment for AF may predispose to gastrointestinal and liver diseases. We review the current literature on the bidirectional associations between gastrointestinal and liver diseases and AF. We highlight the gaps in knowledge and areas requiring future investigation.

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Babesia parasitemia causing splenic infarction: A review of the literature

Case Reports in Internal Medicine ◽

10.5430/crim.v3n3p78 ◽

2016 ◽

Vol 3 (3) ◽

pp. 78

Author(s):

Darren Wong

Keyword(s):

Splenic Infarction ◽

Morbidity And Mortality ◽

Diagnosis And Treatment ◽

Review Of The Literature ◽

Significant Morbidity

Babesia remains an underappreciated and under-diagnosed tick-borne pathogen which can lead to significant morbidity and mortality. We present an uncommon manifestation of parasitemia causing splenic infarction. The pathophysiology is reviewed highlighting the significant challenges in diagnosis and treatment of this unique pathogen.

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Evaluation of an Electronic Dosing Calculator to Reduce Pediatric Medication Errors

Clinical Pediatrics ◽

10.1177/0009922818821871 ◽

2019 ◽

Vol 58 (4) ◽

pp. 413-416

Author(s):

Brian Murray ◽

Matthew J. Streitz ◽

Michael Hilliard ◽

Joseph K. Maddry

Keyword(s):

Patient Safety ◽

Medication Errors ◽

Prospective Cohort ◽

Pediatric Patients ◽

Cohort Analysis ◽

Morbidity And Mortality ◽

Patient Visit ◽

Significant Morbidity ◽

Potential Source ◽

Medication Dosage

Introduction. Adverse medication events are a potential source of significant morbidity and mortality in pediatric patients, where dosages frequently rely on weight-based formulas. The most frequent occurrence of medication errors occurs during the ordering phase. Methods. Through a prospective cohort analysis, we followed medication errors through patient safety reports (PSRs) to determine if the use of a medication dosage calculator would reduce the number of PSRs per patient visits. Results. The number of PSRs for medication errors per patient visit occurring due to errors in ordering decreased from 10/28 417 to 1/17 940, a decrease by a factor of 6.31, with a χ2 value of 4.063, P = .0463. Conclusion. We conclude that the use of an electronic dosing calculator is able to reduce the number of medication errors, thereby reducing the potential for serious pediatric adverse medication events.

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Pulmonary Hemorrhage in the Neonate

Neonatal Network The Journal of Neonatal Nursing ◽

10.1891/11-t-696 ◽

2021 ◽

Vol 40 (5) ◽

pp. 295-304

Author(s):

Megan Alexandra Welde ◽

Cassidy Brooke Sanford ◽

Melissa Mangum ◽

Christy Paschal ◽

Amy J. Jnah

Keyword(s):

Early Identification ◽

Diagnostic Testing ◽

Pulmonary Hemorrhage ◽

Underlying Disease ◽

Morbidity And Mortality ◽

Current Evidence ◽

Exogenous Surfactant ◽

Significant Morbidity ◽

Proactive Management ◽

Surfactant Administration

Pulmonary hemorrhage (PH) is a pathology associated with significant morbidity and mortality, particularly among preterm infants in the NICU. The diagnosis is made when hemorrhagic secretions are aspirated from the trachea concurrent with respiratory decompensation that necessitates intubation or escalated support. The implementation of mechanical ventilation and widespread exogenous surfactant administration have significantly reduced respiratory morbidities. However, when PH develops, death remains the most common outcome. Treatment for PH remains primarily supportive; thus, a thorough understanding of underlying disease processes, manifestations, diagnostic testing, and current evidence is vital to enable early identification and proactive management to reduce morbidity and mortality.

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Brain Studded with Innumerable Larger Stones: Starry Sky at Night Appearance: Multiple Calcified Giant Tuberculoma with 15 Years of Follow-up

Indian Journal of Neurosurgery ◽

10.1055/s-0037-1601365 ◽

2017 ◽

Vol 06 (02) ◽

pp. 155-158

Author(s):

Guru Satyarthee ◽

P. Chandra ◽

A. Mahapatra

Keyword(s):

Central Nervous System Involvement ◽

Definitive Diagnosis ◽

Shunt Surgery ◽

Unique Case ◽

Major Health Problem ◽

Major Health ◽

Vp Shunt ◽

Cranial Ct ◽

Rising Incidence

AbstractTuberculosis is rapidly reemerging as a major health problem due to rising incidence of HIV cases across the globe. Central nervous system involvement is rare, but rarely multiple intracerebral granulomas can occur or occasional solitary tuberculoma also develops. The authors report a unique case of 24-year-old woman suffering from pulmonary tuberculosis developed headache and vomiting. Cranial CT scan revealed multiple widespread deposit of intracranial granuloma of sizeable lesion mimicking starry sky at night appearance. Excision of one tuberculoma was done for confirmation of definitive diagnosis, and histopathology was suggestive of tuberculoma. The patient also underwent VP shunt surgery. At last follow-up at 15 years following surgery, she was doing well.

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Unusual Gross Pneumocephalus and Pneumoperitoneum after VP Shunt Surgery: A Case Report

Journal of Neonatal Surgery ◽

10.47338/jns.v4.174 ◽

2015 ◽

Vol 4 (2) ◽

Author(s):

A Khanolkar ◽

YK Sarin

Keyword(s):

Case Report ◽

Unusual Case ◽

Shunt Surgery ◽

Vp Shunt ◽

Shunt Procedure ◽

Surgical Emphysema

We report an unusual case where a two-month infant developed a simultaneous and spontaneous pneumocephalus and gross pneumoperitoneum along with progressive surgical emphysema after VP shunt procedure.

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Internal Trauma, Humeral Fracture, and Radial Nerve Paralysis: How Could it Occur in the Sport Setting? A Case Report and Review of the Literature

Advances in Bioscience and Clinical Medicine ◽

10.7575/aiac.abcmed.v.8n.1p.1 ◽

2020 ◽

Vol 8 (1) ◽

pp. 1

Author(s):

Elghoul Naoufal ◽

Elantri Ismail ◽

Bouya Ayoub ◽

Bennis Azzelarab ◽

Zaddoug Omar ◽

...

Keyword(s):

Radial Nerve ◽

Full Range ◽

Humeral Fracture ◽

Imaging Findings ◽

Review Of The Literature ◽

Significant Morbidity ◽

Nerve Paralysis ◽

Pathologic Fractures ◽

Type Of Fracture

Thrower’s fractures are Spiral fractures of the humerus in the ball. They represent very uncommon clinical entities that can simulate pathologic fractures. Moreover, the concomitant neurologic deficient is rare. Herein we report a 27 years old muscular man presented a spiral fracture of the humerus following a forceful throw of the ball during an amateur throwing challenge. Clinical and imaging findings showed a displaced Thrower fracture with radial nerve neurapraxia (known as Holstein Lewis fracture) prompting the patient to undergo surgery. The intraoperative aspect found that the nerve was near to the beveled distal humeral fragment with no incarceration. We performed an internal fixation using the Leicester plate and the nerve was kept away from the plate by the interposition of a soft tissue sheet. At the last follow up, the fracture united and radial nerve neurapraxia resolved and the patient regained the full range of motion of his right upper limb with no pain. In conclusion, although this type of fracture is rare, given their significant morbidity, we emphasize that the reactional throwers should undergo appropriate preseason training before practicing a throwing challenge or generally a throwing sport.

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Mucormycosis in CAPA, a Possible Fungal Super-Infection

Journal of Fungi ◽

10.3390/jof7090708 ◽

2021 ◽

Vol 7 (9) ◽

pp. 708

Author(s):

Paola Saltini ◽

Emanuele Palomba ◽

Valeria Castelli ◽

Marco Fava ◽

Laura Alagna ◽

...

Keyword(s):

Pulmonary Infection ◽

Morbidity And Mortality ◽

Significant Morbidity ◽

Pulmonary Aspergillosis ◽

First Case ◽

Super Infection

The occurrence of pulmonary fungal superinfection due to Aspergillus spp. in patients with COVID-19 is a well-described complication associated with significant morbidity and mortality. This can be related to a directed effect of the virus and to the immunosuppressive role of the therapies administered for the disease. Here, we describe the first case of pulmonary infection due to Mucorales occurring in a patient with a concomitant diagnosis of COVID-19-associated pulmonary aspergillosis.

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Phage-based detection of bacterial pathogens

The Analyst ◽

10.1039/c4an00208c ◽

2014 ◽

Vol 139 (11) ◽

pp. 2617-2626 ◽

Cited By ~ 30

Author(s):

R. G. van der Merwe ◽

P. D. van Helden ◽

R. M. Warren ◽

S. L. Sampson ◽

N. C. Gey van Pittius

Keyword(s):

Drug Resistance ◽

Bacterial Pathogens ◽

Morbidity And Mortality ◽

Significant Morbidity ◽

Bacterial Detection

Bacterial pathogens cause significant morbidity and mortality annually to both humans and animals. With the spread of drug resistance and the diminishing effectiveness of antibiotics, there is a pressing need for effective diagnostics for detection of bacterial pathogens. Bacteriophages offer several unique opportunities for bacterial detection. This review highlights the means by which bacteriophages have been utilized to achieve and facilitate specific bacterial detection.

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Smallpox Vaccination

PEDIATRICS ◽

10.1542/peds.49.6.922a ◽

1972 ◽

Vol 49 (6) ◽

pp. 922-923

Author(s):

Edward B. Shaw

Keyword(s):

United States ◽

Herd Immunity ◽

The United States ◽

Morbidity And Mortality ◽

Routine Immunization ◽

Smallpox Vaccination ◽

Significant Morbidity

The zero incidence of smallpox in the United States for so many years, and the significant morbidity and mortality from vaccination, has led to the acceptable and desirable recommendation that routine immunization against smallpox be discontinued. However appropriate this step may seem, it will pose a number of new problems which will involve the pediatrician especially. (1) For many years, smallpox vaccination has been an almost sacred tenet, an immunologic gospel to the population, and has been credited with the conquest of this disease in this country—even though herd immunity could hardly be said to have existed here. Public reeducation is a hazardous matter.

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