scholarly journals Duration of Hormonal Contraception and Risk of Cervical Cancer

2019 ◽  
Vol 14 (1) ◽  
Author(s):  
Yuni Kusmiyati ◽  
Annisaputri Prasistyami ◽  
Heni Puji Wahyuningsih ◽  
Hesty Widyasih ◽  
Qorinah Estiningtyas Sakilah Adnani

The use of long hormonal contraceptives can disrupt the balance of estrogen in the body, resulting in abnormal cell changes. This study aimed to determine a correlation between the duration of hormonal contraception and risk of cervical cancer. This study used a case-control design. The population  were patients who had examined at a cancer installation and obstetrics-gynecology polyclinic Dr. Sardjito Hospital in 2018. Case samples were 95 women have cervical cancer diagnosis and control were 95 women with a negative pap smear. Sampling with random sampling. Dependent variable cervical cancer and independent variable the duration of hormonal contraception are obtained from medical records. Cervical cancer is assessed by doctor’s diagnosis. Data analysis used logistic regression. Results showed that 44.7% of samples used long-term hormonal contraception (over 5 years). Length of use of hormonal contraception had a significant correlation with the incidence of cervical cancer (p-value < 0.01). Hormonal contraceptive use more than 5 years have a risk 4.2 times (95% CI 1.01-5.69) of cervical cancer than using less than 5 years after being controlled with the first marriage age and parity

2020 ◽  
Vol 10 (2) ◽  
pp. 101-110
Author(s):  
Yusri Kartika ◽  
Sudarto Ronoatmodjo

Abstract Background: Prevalence of obesity in adult females in Indonesia is 32,9% in 2013. Hormonal contraceptives (pills, injections and implants) are widely used by reproductive-age women in Indonesia, and the prevalence is 45%. Objective: The aim of this study is to identify whether reproductive-age women who use hormonal contraceptives are at risk of developing obesity compared to WUS who do not use hormonal contraceptives. Method: The design of this study is a cross sectional study using secondary data (5th Indonesia Family Life Survey, and the sample is reproductive-age women (15-49 years old) consisting of 6045 respondents. The variables of this study are obesity, hormonal contraceptive use, age, education, occupation, and duration of contraceptive use. Data were analysed by using Cox Regression. Result: The results of bivariate analysis showed that hormonal contaceptive use, age, education, occupation, and duration of contraceptive use were associated with obesity among reproductive-age womenand statistically significant (P-Value <0,05). Multivariate analysis showed that hormonal contraceptive use did not increase the risk of obesity among reproductive-age women in Indonesia (PR 0.939; CI 95% 0.869 - 1.013). Conclusion: The use of hormonal contraception did not increase the risk of obesity among reproductive-age women. Key words: Hormonal Contraception; Obesity; Reproductive Age-Women Abstrak Latar belakang : Prevalensi obesitas pada perempuan dewasa di Indonesia sebesar 32,9 persen pada tahun 2013. Kontrasepsi hormonal (pil, suntikan dan implan) merupakan jenis kontrasepsi yang paling banyak digunakan oleh wanita usia subur (WUS) di Indonesia, dengan prevalensi sebesar 45%. Tujuan : untuk mengetahui apakah wanita usia subur (WUS) yang menggunakan kontrasepsi hormonal berisiko mengalami obesitas dibandingkan WUS yang tidak menggunakan kontrasepsi hormonal.  Metode : Desain penelitian ini adalah studi cross- sectional dengan menggunakan data sekunder IFLS 5 tahun 2014. Sampel adalah WUS (15-49 tahun) sebanyak 6.045 responden. Variabel dalam penilitian ini adalah obesitas pada WUS, penggunaan kontrasepsi hormonal, umur, pendidikan, pekerjaan, serta lama penggunaan kontrasepsi. Analisis data yang digunakan adalah Cox Regression. Hasil : Hasil analisis bivariat menunjukkan bahwa variabel penggunaan kontrasepsi hormonal, umur, pendidikan dan status pekerjaan, serta  lama penggunaan kontrasepsi berhubungan dengan obesitas pada WUS (p-value <0,05). Analisis multivariat menunjukkan bahwa penggunaan kontrasepsi hormonal tidak meningkatkan risiko obesitas secara bermakna pada WUS di Indonesia (PR 0,939; CI 95% 0,869 – 1,013). Kesimpulan: Penggunaan kontrasepsi hormonal tidak meningkatkan risiko WUS untuk mengalami obesitas.   Kata kunci: Kontrasepsi Hormonal; Obesitas; Wanita Usia Subur


2021 ◽  
Vol 14 (1) ◽  
pp. 63-67
Author(s):  
Nur Zuwariah ◽  
Rizki Amalia ◽  
Syafaatul Ainiyah

One of the most dangerous diseases for Indonesian women is cervical cancer. Hormonal contraceptive use is one of the risk factors for cervical cancer, especially in prolonged use for more than five years. This study evaluates the correlation between hormonal contraceptive use with cervical cancer incidence in Surabaya Wisnuwardhana Cancer Foundation. In this research, the authors used the analytical design with the cross-sectional approach. There were 30 respondents selected with the purposive sampling technique. The independent variable was hormonal contraceptive use, and the dependent variable was cervical cancer incidence. The instruments utilized questionnaires and medical records. Data analysis applied the Rank-spearman test with the significance level of α = 0.05. The results showed that most of the respondents (63,3%) used hormonal contraception. Almost half of them (46.7%) are categorized in class 2 of pap smear classification (mild infection). Hormonal contraceptive use correlated with cervical cancer incidence (p=0.005). The prolonged hormonal contraceptive use, the greater cervical cancer incidence in women.  


bionature ◽  
2019 ◽  
Vol 20 (2) ◽  
pp. 123
Author(s):  
Amiruddin Amiruddin ◽  
Agriansyah A Agriansyah A ◽  
Risna Risna

Abstract. Based on initial observations on hormonal contraceptive KB acceptors in the working area of the Jati Raya Health Center in Kendari City, many acceptors experience menstrual disorders. This study aims to determine the relationship between duration of use and the type of hormonal contraception used with menstrual disorders inactive family planning acceptors in the working area of Jati Raya Health Center, Kendari City. This type of research is an association with the Cross-Sectional Study design. The population in this study was 153 acceptors. The sample was determined by purposive sampling of 138 respondents using a questionnaire. The results showed respondents with a duration of use <6 months (45.7%), 6 months - 1 year (31.2%), and> 1 year (23.2%), the type of hormonal contraception used is; injections (80.4%), pills (13.8%) and implants (5.8%), menstrual disorders before using hormonal contraceptives namely; normal (39.1%) and mild disorders (60.9%) and after using hormonal contraception, mild disorders (15.9%), moderate (39.1%) and severe (44.9%). The results of data analysis with the chi-square test concluded that the length of hormonal contraceptive use was significantly related to menstrual disorders in active KB acceptors in the working area of the Jati Raya Health Center in Kendari City and the type of hormonal contraception used was significantly related to menstrual disorders in active KB acceptors in the Puskesmas work area. Jati Raya Kendari City (p <0.05). Keywords: old, hormonal contraception, menstrual disorders, family planning acceptors.


2021 ◽  
Vol 2 (4) ◽  
pp. 214-218
Author(s):  
Destri Safhira Siahaan ◽  
Adek Amansyah ◽  
Irza Haicha Pratama

The change in the pattern and timing of menopause is an exciting and exploratory phenomenon that requires more detailed research to be carried out using hormonal contraception. This study was aimed to explore the relationship between hormonal contraceptive use and menopausal age. This study used a cross-sectional design. The study was conducted at Royal Prima General Hospital Medan from May to August 2021. A total of 68 research subjects participated in this study with the following inclusion criteria: menopausal women, aged 50-60 years, using hormonal contraceptives (pills, injections, implants), able to remember history previous contraceptive use. This study uses primary data obtained directly from guided interviews with respondents. Participants were dominated by ≥ 55 years old women with 57 people (83.81%), 62 Muslims (91.2%), menarche age >13 years as many as 28 people (41.2%). The number of children 2-4 were 32 people (47.1%) with an average menopause age of 51.93 and the smallest for 1 was 8 people (11.8%) with an average menopause age of 50.37. There were 49 users of hormonal contraception (72.1%) and 48 people (70.6%). In conclusion, we found that the use of hormonal contraceptives is significantly related to menopausal age.


2021 ◽  
Vol 19 (1) ◽  
pp. 25-40
Author(s):  
SASTRA JENDRA HAYUNINGTYAS

Background: cervical cancer as the highest case in Indonesia in 2013, especially in the regions of East Java and Central Java. For the main cause itself is a persistent infection of the Human Papilloma Virus (HPV). However, there are also many factors that can be a risk such as age, parity, hormonal contraceptive use, and sexual activity. Because of the high incidence of cervical cancer in East Java, the purpose of this study was to determine the profile of cervical cancer events in Rumkital DR Ramelan Surabaya during the period January - December 2018. Method : descriptive study with a qualitative approach carried out at the Rumkital Oncology Clinic DR Ramelan surabaya during May - August 2019. The results showed that the majority of cervical cancer cases occur in women > 51 years old. Women with a history of parity ≥ 3 children have the highest percentage of 60%. The age group for first sexual intercourse has the same incidence both at age ≤ 20 years and > 20 years which is 50%. As many as 60% of women have a history of hormonal contraceptive use longer than 4 years. And the highest history of changing sexual partners occurred in those with only one sexual partner, which was 93.3%. Conclusions women aged > 51 years, have a history of parity ≥ 3 children, have sex at an early age ≤ 20 years, and use hormonal contraception ≥ 4 years, have a high risk of being cervical cancer.   Keywords: cervical cancer, age, parity, age at first sexual intercourse, duration of use of hormonal contraception, multiple sexual partners.


2014 ◽  
Vol 1 (2) ◽  
Author(s):  
Mulyana Hasan

ABSTRACT Obesity is caused by several factors, one of them is the use of contraception in particular the use of hormonal contraceptives that its use can cause various side effects such as changes in body weight-acceptor. The research aims to determine the relation of hormonal contraceptive use with obesity in women of childbearing age (WUS) of public health insurance participants in the Wawonasa clinic. This study is an Observational Analytics with cross-sectional and conducted in Wawonasa clinic Singkil district Manado with data collection in the form of identity, body weight, height, and direct interviews with the respondents. The total sample of 77 respondents. The respondents who use hormonal contraception are 49 respondents while the respondents who did not use contraception are 28 respondents. The respondents who use hormonal contraception and were obese are 22 respondents. Conclusion: The type of contraception most widely used by women of childbearing age at Puskesmas Wawonasa is hormonal contraceptives and there is no relationship between the use of contraception with obesity in women of childbearing age at Wawonasa clinic. Keywords: hormonal contraceptives, obesity, women of childbearing age ABSTRAK Obesitas disebabkan oleh beberapa faktor, salah satunya penggunaan kontrasepsi khususnya kontrasepsi hormonal yang penggunaannya dapat menimbulkan berbagai efek samping seperti perubahan berat-badan akseptor. Penelitian bertujuan untuk mengetahui hubungan penggunaan kontrasepsi dengan obesitas pada wanita usia subur (WUS) peserta jamkesmas di Puskesmas Wawonasa. Penelitian ini bersifat Observasional Analitik dengan pendekatan cross-sectional dan dilakukan di Puskesmas Wawonasa Kecamatan Singkil Manado dengan pengambilan data berupa identitas, berat badan, tinggi badan, dan wawancara langsung terhadap responden. Jumlah sampel sebanyak 77 responden. Jumlah responden yang menggunakan kontrasepsi hormonal sebanyak 49 responden sedangkan yang tidak menggunakan kontrasepsi berjumlah 28 responden. Jumlah responden yang menggunakan kontrasepsi hormonal dan mengalami obesitas sebanyak 22 responden. Kesimpulan: Jenis kontrasepsi yang paling banyak digunakan oleh wanita usia subur Puskesmas Wawonasa adalah kontrasepsi hormonal dan tidak terdapat hubungan antara penggunaan kontrasepsi dengan obesitas pada wanita usia subur puskesmas Wawonasa. Kata kunci: kontrasepsi hormonal, obesitas, wanita usia subur


BMJ Open ◽  
2018 ◽  
Vol 8 (10) ◽  
pp. e022473 ◽  
Author(s):  
Helena Hognert ◽  
Finn Egil Skjeldestad ◽  
Kristina Gemzell-Danielsson ◽  
Oskari Heikinheimo ◽  
Ian Milsom ◽  
...  

ObjectivesCompare hormonal contraceptive use, birth and abortion rates among teenagers in the Nordic countries. A secondary aim was to explore plausible explanations for possible differences between countries.DesignEcological study using national registry data concerning births and abortions among all women aged 15–19 years residing in Denmark, Finland, Iceland, Norway and Sweden 2008–2015. Age-specific data on prescriptions for hormonal contraceptives for the period 2008–2015 were obtained from national databases in Denmark, Norway and Sweden.SettingDenmark, Finland, Iceland, Norway and Sweden.ParticipantsWomen 15–19 years old in all Nordic countries (749 709) and 13–19 years old in Denmark, Norway and Sweden (815 044).ResultsBoth annual birth rates and abortion rates fell in all the Nordic countries during the study period. The highest user rate of hormonal contraceptives among 15–19-year-olds was observed in Denmark (from 51% to 47%) followed by Sweden (from 39% to 42%) and Norway (from 37% to 41%). Combined oral contraceptives were the most commonly used methods in all countries. The use of long-acting reversible contraceptives (LARC), implants and the levonorgestrel-releasing intrauterine systems, were increasing, especially in Sweden and Norway. In the subgroup of 18–19-year-old teenagers, the user rates of hormonal contraceptives varied between 63% and 61% in Denmark, 56% and 61% in Norway and 54% and 56% in Sweden. In the same subgroup, the steepest increase of LARC was seen, from 2% to 6% in Denmark, 2% to 9% in Norway and 7% to 17% in Sweden.ConclusionsBirth and abortion rates continuously declined in the Nordic countries among teenagers. There was a high user rate of hormonal contraceptives, with an increase in the use of LARC especially among the oldest teenagers.


Author(s):  
Chidebe Christian Anikwe ◽  
Philip Chidubem Osuagwu ◽  
Cyril Chijioke Ikeoha ◽  
Okechukwu B Ikechukwu Dimejesi ◽  
Bartholomew Chukwunonye Okorochukwu

Background Cervical cancer is a preventable disease that contributes significantly to the death of women. This study is aimed at determining the level of knowledge and utilization of cervical cancer screening and its determinants among female undergraduates of Ebonyi State University. Methods A structured questionnaire was used for a cross-sectional survey of the study population between January 1 and March 3, 2018. The data were analyzed using IBM SPSS Statistics version 20. Data were represented with frequency table, simple percentage, mode, range, Chi square and pie chart. The level of significance is at P-value < 0.05. Results Majority (74.8%) of the respondents were aware of cervical cancer and it could be prevented (70.8%). More than three-fifths (68.30%) were informed via health workers, and 86.8% were aware that post-coital vaginal bleeding is a symptom. Less than half (49.8%) knew that HPV is the primary cause, and only 32.9% were aware of the HPV vaccine. One-quarter of the respondent were aware that early coitarche is a risk factor for cervical cancer. Only 41.8% of the women were aware of Pap smear, 9.2% had undergone screening, and 97.6% were willing to be screened. Marital status was the significant determinant of being screened while class level did not significantly influence uptake of cervical cancer screening. The most common reason (20.6%) for not being screened was lack of awareness of the test. Conclusion Our study population had a good knowledge of cervical cancer, but utilization of cervical cancer screening was poor. Awareness creation through the mass media and provision of affordable screening services can promote the use of cervical cancer screening in the study area.


2012 ◽  
Vol 3 (3) ◽  
Author(s):  
Megen Leeds Schumacher ◽  
Ashley Cetola Pettia ◽  
Albert I Wertheimer

Background: Extended cycle hormonal contraceptives (e.g. Seasonale, Seasonique) when introduced in 2003 were considered a very novel approach to contraception. The idea of manipulating the menstrual cycle so that women would experience just four menstruations a year was radical and was assumed to be responsible for the slow acceptance rate among the general public. Objective: This report analyzes two different aspects of the acceptance of this unique idea in the population. The first was the level of usage of extended cycle hormonal contraceptives in the general population, which was measured by a review of sales figures over time in the United States. The second was an examination of market diffusion as it relates to consumer perceptions regarding the characteristics of these products. Methods: To determine the degree of usage of extended cycle hormonal contraceptives the yearly sales, in terms of units sold, were compared with that of other leading methods of hormonal contraception. Along with the data, survey answers were obtained from 65 women who volunteered to participate in the study. Participants were selected randomly to represent the target population to assess the level of awareness about the benefits, risks, and any other concerns regarding the use of extended cycle hormonal contraceptives. Results: The yearly sales data of units sold showed a definitive increase in the sales of extended cycle hormonal contraceptives since their release on the market. The survey results showed an overwhelming awareness in the study population about the extended regimen. However, only about half of the women in the survey group were aware of its benefits. The main concern reported was the perceived significant side effect profile. Conclusion: Though awareness about the extended cycle hormonal contraception regimen was widespread, the survey population was not well informed about the advantages and the disadvantages regarding the degree of severity of side effects. To address these knowledge deficits, these aspects should be the focus when distributing information about extended cycle hormonal contraceptive regimens. This may boost the use of a potentially advantageous contraceptive regimen by a population who would derive benefit from its usage.   Type: Original Research


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