scholarly journals Cancer patients/survivors, lymphocytes, and severe COVID-19

2020 ◽  
Author(s):  
Jian-xing He ◽  
Wen-hua liang ◽  
Cai-chen Li ◽  
Jian-fu Li ◽  
Shan Xiong ◽  
...  

Abstract There is a heated debate on whether the cancer survivors have worse outcomes in corona virus disease 2019 (COVID-2019). This study showed that both cancer survivors and cancer patients have decreased lymphocytes, partially explaining why these patients were associated with poorer prognosis in severe acute respiratory syndrome coronavirus 2 infection (SARS-CoV-2) in principle. Therefore, patients with cancer history, whether they are going active treatment or not, deserve special attention.

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 1494-1499
Author(s):  
Shahid Ahmad Siddiqui

The episode of Covid19 (CORONA VIRUS) has become one of the greatest worldwide dangers around the world, which has now tainted over 1.7 million individuals with deaths of over 100,000 lives far & wide. Under these extraordinary conditions, there are no entrenched rules for cancer patients. The danger for genuine infection & passing in CORONA VIRUS cases increments with propelling age & existing co-morbid medical issue. After the rise of primary suspects in China during last month of 2019, enormous exploration endeavors have been in progress to comprehend the instruments of infectivity & contagiousness of coronavirus, a lethal infection liable for wretched endurance results. To limit the death rate, it gets judicious to distinguish indications quickly & utilize medicines suitably. Despite the fact that no fix has been set up, different clinical preliminaries are in progress to decide the most ideal system. Overseeing patients with cancer in these conditions is a fair task, considering their weak immune status & their ill health. Through this thorough audit, we talk about the effect of CORONA VIRUS on wellbeing & the immune system of who are infected, assessing the most recent care plan draws near & progressing clinical preliminaries. Also, we talk about difficulties confronted while treating cancer patients & propose possible ways to deal with these weak populace during pandemic.


Author(s):  
Jahnvi Garg ◽  
Ranjit S. Ambad ◽  
Nandkishor Bankar

Introduction: This article includes the effect of Corona virus disease on cancer patients and their healthcare facilities. The global pandemic mentioned around the world has impacted the most vulnerable group of patients- cancer. With the assistance of RT PCR tests and HRCT, oncologists and doctors have tried to provide treatment to Covid-19 patients. Cancer patients are more susceptible to Covid-19 than non-cancer or non-survivor patients, according to reports. To avoid the prevalence and infection of cancer victims, WHO has suggested staying at home and continuing their treatment through telemedicine unless the situation is critical for which they might require therapy and/or surgery. Covid-19 is here to stay so we should practice with utmost care and precaution.


Author(s):  
Gabriel B. Iwasokun

The corona virus disease, otherwise known as COVID-19, is an extremely communicable and pathogenic viral infection caused by severe acute respiratory syndrome corona virus 2 (SARS-CoV-2), which emerged in Wuhan, China in December 2019 and has spread to almost all the countries in the world. The transmission of the virus is through touching of the nose, eyes, or mouth by a finger that has been contaminated through droplets on a surface when a carrier sneezes or coughs. Since the existing fingerprint devices are predominantly contact based, it implies that they can aid in the transmission of the virus. This paper discusses the application of fingerprint devices in notable places with high rate of COVID-19 infection as well as the threats to fingerprint technologies and the countermeasures. The need to change focus and orientation towards contactless biometric technologies as sure solution to the fear and animosity expressed towards contact-based fingerprint technology is also expatiated.


Author(s):  
Fátima Denise Padilha Baran ◽  
Márcia Marrocos Aristides Barbiero ◽  
Patrícia Rosa Gonçalves Leta ◽  
Susanne Elero Betiolli ◽  
Karina t Silveira de Almeida Hammerschmid ◽  
...  

Introdução: a implementação de ações preventivas e de proteção foram preconizadas para reduzir o contágio Corona Vírus Disease-19 causado pelo vírus Severe Acute Respiratory Syndrome Coronavirus-2. Os idosos residentes em comunidades rurais demonstravam dificuldades em se adaptar às novas medidas. Objetivo: interpretar os significados culturais atribuídos à pandemia de idosos descendentes de ucranianos residentes em zona rural. Método: trata-se de pesquisa qualitativa descritiva sustentada pelos referenciais da antropologia cultural e conduzida pelo Consolidate criteria for reporting qualitative research. Participaram de entrevistas etnográficas nove idosos informantes chaves, por via Skype e chamadas de vídeo pelo whatsapp, no período de março a abril de 2020. As entrevistas foram analisadas segundo domínios culturais. Resultados: Emergiram três domínios: 1- “Providência divina que gerou mudanças” - os idosos atribuem à pandemia o desejo de Deus para gerar um aprendizado e mudança de vida; 2- “O cuidado que vem de Deus e do médico para consigo e com o outro”- eles revelam práticas cotidianas para evitar a contaminação, como fazer o que o médico diz, tomar coisas fortes como os antigos, acreditar em Deus, ficar longe das pessoas que não moram na mesma casa, não sair de casa e não receber visitas; e 3 - “Sentimentos desagradáveis que podem adoecer”- eles apontam como consequências sentimento de tristeza e solidão, dificuldades em aceitar as mudanças impostas, incerteza no futuro. Conclusão: os significados atribuídos à pandemia permearam a intensificação e preservação das crenças e práticas religiosas, e a proteção para a doença percorreu o saber médico e popular. 


2021 ◽  
Vol 9 (6) ◽  
pp. 1223-1226
Author(s):  
Rachna Gupta ◽  
Amit Chowdhary

Today the whole world community is facing an unprecedented pandemic of novel corona virus disease (COVID- 19) caused by Severe Acute Respiratory Syndrome Corona virus 2 (SARS-CoV- 2). The disease has spread glob- ally with more than 20.3 million confirmed cases and 2, 22000 deaths in India only as of May 4, 2021. Despite worldwide efforts, the pandemic is continuing to spread, and no system of medicine has any evidence-based treatment for COVID-19 as yet. The dimensions of pandemic require an urgent harnessing of all knowledge sys- tems available globally. Drawing attention on the Ayurveda classics, contemporary scientific studies, and experi- ential knowledge on similar clinical settings, depending on the stage of infection among individuals, in a popula- tion, Ayurveda system of medicine requires immediate implementation. It will facilitate learning, generate evi- dence and shall be a way forward. Keywords: COVID-19, Pandemic, SARS-CoV-2, Ayurveda, Immunity


Author(s):  
Raunak Manjeet ◽  
KULDEEP D’MELLO ◽  
ATUL SINGH ◽  
SWATI SRIVASTAVA

The outbreak of severe acute respiratory syndrome corona virus 2 (SARS COV 2) and its linked corona virus disease has troubled the entire world community led to a serious public health concerns. Despite the various efforts to stop the spread of this disease globally, the outbreak is still on the rise because of the community spread pattern of this disease. This is believed to have originated in bats pangolins initially later it got transmitted to humans. Once it comes in the human body , this corona virus remains abundantly present in nasopharyngeal and salivary secretions of affected patients. Its spreading nature is mainly through the respiratory droplet spread / aerosol infection. Dental professionals, including Orthodontists , Oral Surgeons , Periodontists, Endodontists and Prosthodontists are all at high risk, since they may encounter patients with suspected or confirmed SARS COV 2 infection will have to act accordingly not only to provide care but at the same time prevent nosocomial spread of infection. Thus, the aim of this article is to provide a brief detailing of the cause, sign symptoms and different routes of transmission of this infection. In addition specific recommendations for dental practice are suggested for patient screening, infection control strategies and patient management protocol . KEY WORDS Coronavirus ,COVID 19, SARS COV 2 ,Dental practice ,Orthodontics ,OMFS, severe acute respiratory syndrome .


2020 ◽  
Author(s):  
Qiang Su ◽  
Jie-xuan Hu ◽  
Hai-shan Lin ◽  
Zheng Zhang ◽  
Emily C. Zhu ◽  
...  

SummaryBackgroundThe corona virus disease 2019 (COVID-19) pandemic poses a severe challenge to public health, especially to those patients with underlying diseases. In this meta-analysis, we studied the prevalence of cancer among patients with COVID-19 infection and their risks of severe events.MethodsWe searched the Pubmed, Embase and MedRxiv databases for studies between December 2019 and May 3, 2020 using the following key words and terms: sars-cov-2, covid-19, 2019-ncov, 2019 novel coronavirus, corona virus disease-2019, clinical, clinical characteristics, clinical course, epidemiologic features, epidemiology, and epidemiological characteristics. We extracted data following PICO (patient, intervention, comparison and outcome) chart. Statistical analyses were performed with R Studio (version 3.5.1) on the group-level data. We assessed the studies’ risk of bias in accordance to the adjusted Joanna Briggs Institute. We estimated the prevalence or risks for severe events including admission into intensive care unit or death using meta-analysis with random effects.FindingsOut of the 2,551 studies identified, 32 studies comprising 21,248 participants have confirmed COVID-19. The total prevalence of cancer in COVID-19 patients was 3.97% (95% CI, 3.08% to 5.12%), higher than that of the total cancer rate (0.29%) in China. Stratification analysis showed that the overall cancer prevalence of COVID-19 patients in China was 2.59% (95% CI, 1.72% to 3.90%), and the prevalence reached 3.79% in Wuhan (95% CI, 2.51% to 5.70%) and 2.31% (95% CI, 1.16% to 4.57%) in other areas outside Wuhan in China. The incidence of ICU admission in cancer patients with COVID-19 was 26.80% (95% CI, 21.65% to 32.67%) and the mortality was 24.32% (95% CI, 13.95% to 38.91%), much higher than the overall rates of COVID-19 patients in China. The fatality in COVID patients with cancer was lower than those with cardiovascular disease (OR 0.49; 95% CI, 0.34 to 0.71; p=0.39), but comparable with other comorbidities such as diabetes (OR 1.32; 95% CI, 0.42 to 4.11; p=0.19), hypertension (OR 1.27; 95% CI, 0.35 to 4.62; p=0.13), and respiratory diseases (OR 0.79; 95% CI, 0.47 to 1.33; p=0.45).InterpretationThis comprehensive meta-analysis on the largest number of patients to date provides solid evidence that COVID-19 infection significantly and negatively affected the disease course and prognosis of cancer patients. Awareness of this could help guide clinicians and health policy makers in combating cancer in the context of COVID-19 pandemic.FundingBeijing Natural Science Foundation Program and Scientific Research Key Program of Beijing Municipal Commission of Education (KZ202010025047).


2021 ◽  
Vol 4 (4) ◽  
pp. 933-940
Author(s):  
Akhmad Kheru Dharmawan ◽  
Ibnu Aji Setyawan ◽  
Nia Triswanti ◽  
Hetti Rusmini ◽  
Ni Putu Sudiadnyani ◽  
...  

ABSTRAK COVID-19 atau Corona Virus Diesease-19 adalah sebuah penyakit terbaru di tahun 2019 yang disebabkan oleh Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). Covid-19 melanda banyak Negara di dunia termasuk Indonesia. Pandemi Covid-19 tidak hanya merupakan masalah nasional dalam suatu negara, tapi sudah merupakan masalah global. Covid-19 berawal dari daerah Wuhan Cina. Penyebaran Covid -19 yang begitu cepat dan beresiko kematian. Penularannya diduga melalui aerosol pada daerah mulut, mata dan hidung. Covid-19 berdampak kepada kehidupan sosial dan melemahnya ekonomi masyarakat yang kemudian mempengaruhi pelayanan publik. Permasalahan yang disoroti adalah bagaimana dampak pandemi Covid-19 terhadap pelayanan publik dan upaya penanggulangan wabah COVID-19.. Tujuan dari kegiatan ini adalah untuk meningkatkan pengetahuan tentang pentingnya melakukan isolasi mandiri untuk memutus rantai penyebaran COVID-19 di lingkungan masyarakat.  Metode yang digunakan dalam kegiatan ini yaitu penyuluhan kepada ibu-ibu kader di wilayah kerja Puskesmas Kedaton tentang pentingnya menjalani protokol kesehatan dan melakukan isolasi mandiri di rumah sebagai tindakan preventif untuk memutus rantai penyebaran COVID-19. Pelaksanaan kegiatan oleh mahasiswa FK Malahayati kelompok 13 CHOP dan pihak puskesmas kedaton dan dilaksanakan pada tanggal 19 Desember 2020. Hasil dari kegiatan ini adalah meningkatnya pengetahuan kader tentang pentingnya penerapan protokol kesehatan di masa pandemi COVID-19 ini sehingga penyuluhan ini berdampak baik dan efektif. Kata Kunci : Edukasi, Kesehatan, Covid  ABSTRACT COVID-19 or Corona Virus Disease 19 is a new illness in 2019 caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Covid-19 hit many countries in the world including Indonesia. The Covid-19 outbreak is not only a national problem in a country but already a global problem. Covid -19 originated in the Wuhan area of China. The spread of Covid-19 is so fast and deadly, transmission through physical contact is transmitted by the aerosol through the mouth, eyes, and nose. Covid-19 has an impact on social life and the weakening of the people's economy. The issue of how the impact of the Covid-19 outbreak on public services and efforts to overcome the Covid-19 outbreak. The Problem that followed is about how’s the impact of the outbreak affects public service. The purpose of this activity is to increase the knowledge about how too important it do self-isolation to cut off the transmission of COVID-19 in the social community. The method that used in this activity is counseling the cadres in the puskesmas kedaton her territory about how too important to do self-isolation to cut off the transmission of COVID-19 in the social community. The activity was assisted by the students of the medical faculty of Malahayati University especially group 13 CHOP and staff of puskesmas kedaton and was held on December 19, 2020. The results of this activity are increased knowledge of the cadres about how too important to do self-isolation to cut off the transmission of COVID-19 in the social community so that can be concluded this counseling worked so well and effectively. Keywords: Education, Health, Covid


2020 ◽  
Vol 7 (8) ◽  
pp. 3906-3915
Author(s):  
Kabeer Haneef ◽  
Muhammad Umer Asghar ◽  
Ashiq Ali

The emerging Corona virus strain (severe acute respiratory syndrome corona virus-2 (SARS-CoV-2)) harbors intricate in the development of corona virus infection (COVID-19)-induced pneumonia and subsequently ameliorates lung infection. Genome sequence and interventions reveal proximal resemblance of corona virus strain COVID-19 with severe acute respiratory syndrome (SARS), transmittable to bats, suggesting similar primary hosts in the spread of infection. However, potential rapid human-to-human transmission has caused therapeutic challenges in treating a wide range of humans suffering from corona virus all over the world. However, up to now, no direct vaccines or antiviral drugs are available to treat COVID-19. Previously designed antiviral drugs and convalescent plasma are undergoing investigations as treatment for COVID-19 infected patients. Therapeutic challenges with regards to COVID-19 have prompted scientists to develop fruitful remedies to combat the pathogen. In this review, we address the role of current ongoing therapeutic strategies, , and complex mechanisms of adaptive immune system (B and T cells) to respond to viruses. Furthermore, we illustrate the current challenges in the treatment of COVID-19, managerial strategies, and ongoing and future perspectives.


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