scholarly journals Genetic correlates of psychological responses to the COVID-19 crisis in young adult twins in Great Britain

2020 ◽  
Author(s):  
Kaili Rimfeld ◽  
Margherita Malancini ◽  
Andrea Allegrini ◽  
Amy E. Packer ◽  
Andrew McMillan ◽  
...  
Keyword(s):  
Young Adults ◽  
Great Britain ◽  
Young Adult ◽  
Genetic Factors ◽  
Psychological Responses ◽  
Phenotypic Stability ◽  
Behavioural Responses ◽  
Negative Direction ◽  
T1 And T2 ◽  
Adult Twins

Abstract We investigated how the COVID-19 crisis and the extraordinary experience of lockdown affected young adults in England and Wales psychologically. One month after lockdown commenced (T2), we assessed 30 psychological and behavioural traits in 4,000 twins in their mid-twenties and compared their responses to the same traits assessed in 2018 (T1). Mean changes from T1 to T2 were modest and inconsistent: just as many changes were in a positive as negative direction. Twin analyses revealed that genetics accounted for about half of the reliable variance at T1 and T2. Genetic factors correlated on average .86 between T1 and T2 and accounted for over half of the phenotypic stability. Systematic environmental influences had negligible impact on T1, T2 or T2 change. Rather than the crisis fundamentally changing people psychologically, our results suggest that genetic differences between individuals play a fundamental role in shaping psychological and behavioural responses to the COVID-19 crisis.

scholarly journals Genetic Correlates of Psychological Responses to the COVID-19 Crisis in Young Adult Twins in Great Britain

2021 ◽  
Author(s):  
Kaili Rimfeld ◽  
Margherita Malanchini ◽  
Andrea G. Allegrini ◽  
Amy E. Packer ◽  
Andrew McMillan ◽  
...  
Keyword(s):  
Young Adults ◽  
Individual Differences ◽  
Genetic Factors ◽  
Environmental Changes ◽  
Phenotypic Stability ◽  
Behavioural Changes ◽  
Gene Environment ◽  
Major Disruption ◽  
T1 And T2 ◽  
Adult Twins

AbstractWe investigated how the COVID-19 crisis and the extraordinary experience of lockdown affected young adults in England and Wales psychologically. One month after lockdown commenced (T2), we assessed 30 psychological and behavioural traits in more than 4000 twins in their mid-twenties and compared their responses to the same traits assessed in 2018 (T1). Mean changes from T1 to T2 were modest and inconsistent. Contrary to the hypothesis that major environmental changes related to COVID-19 would result in increased variance in psychological and behavioural traits, we found that the magnitude of individual differences did not change from T1 to T2. Twin analyses revealed that while genetic factors accounted for about half of the reliable variance at T1 and T2, they only accounted for ~ 15% of individual differences in change from T1 to T2, and that nonshared environmental factors played a major role in psychological and behavioural changes. Shared environmental influences had negligible impact on T1, T2 or T2 change. Genetic factors correlated on average .86 between T1 and T2 and accounted for over half of the phenotypic stability, as would be expected for a 2-year interval even without the major disruption of lockdown. We conclude that the first month of lockdown has not resulted in major psychological or attitudinal shifts in young adults, nor in major changes in the genetic and environmental origins of these traits. Genetic influences on the modest psychological and behavioural changes are likely to be the result of gene–environment correlation not interaction.

Genetic and Environmental Covariations Among Obsessive–Compulsive Symptoms, Neuroticism, and Extraversion in South Korean Adolescent and Young Adult Twins

2009 ◽  
Vol 12 (2) ◽  
pp. 142-148 ◽  
Author(s):  
Yoon-Mi Hur
Keyword(s):  
Young Adult ◽  
Genetic Factors ◽  
Genetic Correlations ◽  
Mental Illnesses ◽  
Adolescent And Young Adult ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
South Korean ◽  
Psychiatric Illnesses ◽  
Adult Twins

AbstractA growing literature suggests that personality traits may be endophenotype markers for psychiatric illnesses. Although the phenotypic relationships between obsessive–compulsive disorder (OCD) and high neuroticism and low extraversion have been well documented, underlying genetic and environmental contributions to these associations have not been explored previously. Five hundred and twenty-four monozygoitc (MZ) and 228 dizygotic (DZ) pairs of adolescent and young adult twins (aged 13–24 years) drawn from the South Korean Twin Registry completed the Maudsley Obsessive Compulsive Inventory (MOCI) and the Neuroticism and Extraversion scale of the Eysenck Personality Scale by mail. The total score of MOCI (MOCIT) was significantly and positively correlated with Neuroticism (r= .44), but only weakly and negatively related to Extraversion (r= –.10). A trivariate Cholesky model was applied to the data. The additive genetic correlations in the best-fitting model were .51 between Neuroticism and MOCIT and –.17 between Extraversion and MOCIT, suggesting that additive genetic factors that lead to high neuroticism and low extraversion overlap with those genetic factors influencing high OC symptoms. These findings add to the cumulative evidence of the shared genetic etiology for the associations between a personality profile of high neuroticism and low extraversion and mental illnesses.

scholarly journals Spatial Similarity of MRI-Visible Perivascular Spaces in Healthy Young Adult Twins

2021 ◽  
Author(s):  
Boeun Lee ◽  
Na-Young Shin ◽  
Chang-hyun Park ◽  
Yoonho Nam ◽  
Soo Mee Lim ◽  
...  
Keyword(s):  
Young Adult ◽  
Genetic Factors ◽  
Perivascular Spaces ◽  
Healthy Young Adult ◽  
Sibling Pairs ◽  
Spatial Similarity ◽  
Human Connectome Project ◽  
Significant Difference ◽  
Adult Twins ◽  
Mz Twins

Abstract Purpose This study aims to determine whether genetic factors affect the location of dilated perivascular spaces (dPVS) by comparing healthy young twins and non-twin (NT) siblings. Methods A total of 700 healthy young adult twins and NT siblings (138 monozygotic (MZ) twin pairs, 79 dizygotic (DZ) twin pairs, and 133 NT sibling pairs) were collected from the Human Connectome Project dataset. dPVS was automatically segmented and normalized to standard space. Then, spatial similarity indices (mean squared error [MSE], structural similarity [SSIM], and dice similarity [DS]) were calculated for dPVS in the basal ganglia (BGdPVS) and white matter (WMdPVS) between paired subjects before and after propensity score matching of dPVS volumes between groups. Within-pair correlations for the regional volumes of dVPS were also assessed using the intraclass correlation coefficient (ICC). Results The spatial similarity of dPVS was significantly higher in MZ twins (higher DS [median, 0.382 and 0.310] and SSIM [0.963 and 0.887] and lower MSE [0.005 and 0.005] for BGdPVS and WMdPVS, respectively) than DZ twins (DS [0.121 and 0.119], SSIM [0.941 and 0.868], and MSE [0.010 and 0.011]) and NT siblings (DS [0.106 and 0.097], SSIM [0.924 and 0.848], and MSE [0.016 and 0.017]). No significant difference was found between DZ twins and NT siblings. Similar results were found even after subjects were matched according to dPVS volume. Regional dPVS volumes were also more correlated within pairs in MZ twins than DZ twins and NT siblings. Conclusion Our results suggest that genetic factors affect the location of dPVS.

Associations between sports participation, cardiorespiratory fitness, and adiposity in young adult twins

2011 ◽  
Vol 110 (3) ◽  
pp. 681-686 ◽  
Author(s):  
L. Mustelin ◽  
A. Latvala ◽  
K. H. Pietiläinen ◽  
P. Piirilä ◽  
A. R. Sovijärvi ◽  
...  
Keyword(s):  
Young Adult ◽  
Body Mass ◽  
Cardiorespiratory Fitness ◽  
Genetic Factors ◽  
Sports Participation ◽  
Population Based ◽  
Bicycle Ergometer ◽  
Fat Percentage ◽  
Ergometer Exercise ◽  
Adult Twins

Exercise behavior, cardiorespiratory fitness, and obesity are strongly influenced by genetic factors. By studying young adult twins, we examined to what extent these interrelated traits have shared genetic and environmental etiologies. We studied 304 twin individuals selected from the population-based FinnTwin16 study. Physical activity was assessed with the Baecke questionnaire, yielding three indexes: sport index, leisure-time index, and work index. In this study, we focused on sport index, which describes sports participation. Body composition was determined using dual-energy X-ray absorptiometry and cardiorespiratory fitness using a bicycle ergometer exercise test with gas exchange analysis. The Baecke sport index was associated with high maximal oxygen uptake adjusted for lean body mass (V̇o2max[adj]) ( r = 0.40), with low body fat percentage (BF%) ( r = −0.44) and low waist circumference (WC) ( r = −0.29). Heritability estimates for the key traits were as follows: 56% for sport index, 71% for V̇o2max[adj], 77% for body mass index, 66% for WC, and 68% for BF%. The association between sport index and V̇o2max was mostly explained by genetic factors (70%), as were both the association between sport index and BF% (71%) and that between sport index and WC (59%). Our results suggest that genetic factors explain a considerable part of the associations between sports participation, cardiorespiratory fitness, and obesity.

scholarly journals Liver Fat But Not Other Adiposity Measures Influence Circulating FGF21 Levels in Healthy Young Adult Twins

2011 ◽  
Vol 96 (2) ◽  
pp. E351-E355 ◽  
Author(s):  
Henna Tyynismaa ◽  
Taneli Raivio ◽  
Antti Hakkarainen ◽  
Alfredo Ortega-Alonso ◽  
Nina Lundbom ◽  
...  
Keyword(s):  
Young Adult ◽  
Body Fat ◽  
Genetic Factors ◽  
Fat Content ◽  
Liver Fat ◽  
Fibroblast Growth Factor 21 ◽  
Oral Glucose ◽  
Model Assessment ◽  
Healthy Young Adult ◽  
Adult Twins

abstract Context: Emerging as an important metabolic regulator, fibroblast growth factor 21 (FGF21) has gained considerable interest in diabetes and obesity research. The circulating FGF21 concentration is fairly low in normal individuals, but elevated hormone levels may associate with obesity. The determining factors of FGF21 levels in humans are not clear. Objective: Our objective was to study the influence of genetic and acquired components to serum FGF21 variability in healthy young adult twins. Design and Participants: Fasting serum FGF21, lipids, body fat, and oral glucose tolerance test were investigated in 46 monozygotic (MZ) and 75 dizygotic twin pairs aged 22.8–33.1 yr. Subcutaneous, intraabdominal, and liver fat content were measured by magnetic resonance imaging/spectroscopy in a subsample of 24 MZ pairs. Results: Genetic factors contributed moderately (heritability 40%) to circulating serum FGF21 levels. Subjects with high FGF21 concentrations (≥ 250 pg/ml, n = 30) had higher fasting triglycerides, insulin, homeostasis model assessment index, and area under the curve glucose and lower high-density lipoprotein cholesterol but similar measures of overall adiposity (body mass index, body fat percent) than subjects with lower FGF21 (<100 pg/ml, n = 148). Importantly, in the MZ subsample, higher liver fat but not sc or intraabdominal fat content was found in subjects with high FGF21. Furthermore, in analyses controlling for genetic/familial effects in twin pairs, within-pair differences in liver fat (MZ) and triglycerides (dizygotic pairs) were the major acquired factors that correlated with differences in FGF21 concentrations. Conclusions: Genetic factors influence serum FGF21 levels. Of the acquired components, high liver fat and triglycerides rather than overall adiposity associate with high FGF21 levels.

Sexual Dimorphism among the Kathmandu University Students Assessed by Anthropometric Studies

2018 ◽  
Vol 9 (05) ◽  
pp. 20469-20472
Author(s):  
Shakya R ◽  
Bhattacharya SC ◽  
Shrestha R
Keyword(s):  
Young Adults ◽  
Sexual Dimorphism ◽  
Young Adult ◽  
University Students ◽  
Plastic Surgery ◽  
Age Group ◽  
Adult Age ◽  
Clinically Normal ◽  
Crime Detection ◽  
Males And Females

Objectives: To observe the sexual dimorphism among the young adult age group ranging from 18-21 years, of Kathmandu University students by measuring craniofacial circumference and canthal distances. Rationale of the study: These data could be useful for establishing the craniofacial standards and adds an implementation on plastic surgery, crime detection as well as in the industrial field. Method: 300 clinically normal students of Kathmandu University aged between 18-21 years were examined for the study. Fronto-occipital circumference, outer and inner canthal distances were measured. All the parameters were compared between males and females. Result: The cranial circumference as well as the inner and outer canthal distance in males was found to be significantly higher as compared to the females. Conclusion: The results concluded that sexual dimorphism remarkably exists in young adults of Kathmandu University students.

JUVENTUDE, TRABALHO INFORMAL E SAÚDE MENTAL

2020 ◽  
pp. 126-144
Author(s):  
Marina Batista Chaves Azevedo de Souza ◽  
Isabela Aparecida de Oliveira Lussi
Keyword(s):  
Mental Health ◽  
Young Adults ◽  
Young Adult ◽  
Informal Sector ◽  
Informal Work ◽  
Informal Workers

Estudos apontam que jovens podem exercer trabalhos informais por necessidade não por desejo pessoal, o que pode acarretar impactos negativos na saúde mental. O objetivo do artigo foi apontar abordagens, destacar problemáticas e realizar reflexões sobre juventude, trabalho informal e saúde mental, através do mapeamento de estudos científicos. Realizou-se uma revisão de escopo pelo modelo de Arksey e O’Malley para mapear/sintetizar os estudos. Foram encontrados 51 artigos com a expressão: "informal work" OR "informal workers" OR "informal sector" OR "informal job" OR informality AND "mental health" AND "young adult" OR "young adults" OR young OR youth e 2640 teses e dissertações. Após as exclusões das duplicações, ensaios teóricos, revisões, trabalhos indisponíveis e estudos em que os títulos e resumos não abordavam a temática central, analisou-se 6 artigos científicos e 3 dissertações na íntegra. Os estudos são de anos diversos, a maioria quantitativos e investigam associações entre trabalhos informais/precários/desemprego e sintomas psiquiátricos. Questões geracionais não foram consideradas indicadoras de peculiaridades sobre o assunto nos artigos, mas duas dissertações trouxeram essa discussão. Foram inexistentes artigos que priorizam percepções do trabalhador sobre sua condição de trabalho/saúde, todavia, uma das dissertações analisadas abordou as condições sociais e o trabalho precário como sugestivos a problemas de saúde. Indica-se como necessário realizar reflexões que articulem saúde mental a condições políticas/socioeconômicas, considerando o trabalho como determinante de saúde/doença e a juventude como detentora de idiossincrasias que influenciam nas reflexões sobre o tema.

“I wouldn’t call them Muslims!”: Constructing a Respectable Islam

Numen ◽  
2015 ◽  
Vol 62 (2-3) ◽  
pp. 243-264
Author(s):  
Jonas Otterbeck
Keyword(s):  
Young Adults ◽  
Young Adult ◽  
Daily Life ◽  
Sociology Of Religion ◽  
Theoretical Framework ◽  
Dominant Discourse ◽  
The Media ◽  
Mainstream Society

This article addresses the understanding of Islam of nine young adult Muslims living in the Malmö and Copenhagen region.1 Throughout the interviews with the young adults, they mark their distance from what they perceive as unacceptable forms of Islamic ideas and practices, labeling these ideas as extremist and inconsistent. They develop discursive techniques of distancing themselves from the mediated Islam of radicals and the often negative rendering of Islam that they encounter in daily life and in the media. By negotiating with the dominant discourse on what a “respectable religion” should look like, the young adults construct a religiosity that shares much of theformprescribed by mainstream society, but is different incontent. The theoretical framework is drawn from the study of sociology of religion and, in particular, from Beverley Skeggs’ theories on respectability (1997).

Navigating being a young adult with cerebral palsy: a qualitative study

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Gitte Normann ◽  
Kirsten Arntz Boisen ◽  
Peter Uldall ◽  
Anne Brødsgaard
Keyword(s):  
Young Adults ◽  
Cerebral Palsy ◽  
Young Adult ◽  
Qualitative Study ◽  
Healthcare System ◽  
Young Adulthood ◽  
Educational Background ◽  
Pediatric Care ◽  
Healthcare Needs ◽  
New Challenges

AbstractObjectivesYoung adults with cerebral palsy (CP) face potential challenges. The transition to young adulthood is characterized by significant changes in roles and responsibilities. Furthermore, young adults with chronic conditions face a transfer from pediatric care to adult healthcare. This study explores how living with CP affects young adults in general, and specifically which psychosocial, medical and healthcare needs are particularly important during this phase of life.MethodsA qualitative study with data from individual, semi-structured, in-depth interviews with six young adults with CP (ages 21–31 years) were transcribed verbatim and analyzed. The participants were selected to provide a maximum variation in age, gender, Gross Motor Function Classification System score and educational background. A descriptive thematic analysis was used to explore patterns and identify themes.ResultsThree themes were identified: “Being a Young Adult”, “Development in Physical Disability and New Challenges in Adulthood” and “Navigating the Healthcare System”. The three themes emerged from 15 sub-themes. Our findings emphasized that young adults with CP faced psychosocial challenges in social relationships, participation in education and work settings and striving towards independence. The transition to young adulthood led to a series of new challenges that the young adults were not prepared for. Medical challenges included managing CP-related physical and cognitive symptoms and navigating adult health care services, where new physicians with insufficient knowledge regarding CP were encountered.ConclusionThe young adults with CP were not prepared for the challenges and changes they faced during their transition into adulthood. They felt that they had been abandoned by the healthcare system and lacked a medical home. Better transitional care is urgently needed to prepare them for the challenges in young adulthood.

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