scholarly journals Case report: Pediatric patients with COVID-19 presented as multi-system inflammatory syndrome

2020 ◽  
Author(s):  
Amir Saeed ◽  
anahita sanaei ◽  
shabnam Hajiani Ghotbabadi ◽  
Eslam shorafa

Abstract Background COVID-19 in pediatric patients is typically associated with minimal manifestations and is less severe than adult patients. Recently, there are reports of children with COVID 19 and myocardial involvement from Europe and America that first were assumed to be Kawasaki disease or its atypical presentation. However world health organization has set a new designation for this state; “multi-system involvement syndrome” in children with COVID-19; (MIS-C). Case presentation: Here we report two COVID-19 pediatric patients (two girls aged 10 and 13 years old) with MIS-C. Conclusion Presence of Kawasaki like signs in COVID 19 patients should be an alarming point to consider multi-system inflammatory syndrome; a syndrome with extensive organ involvement and yet indistinct exact pathophysiology.

1970 ◽  
Vol 1 (1) ◽  
pp. 56-58
Author(s):  
SC Kohli ◽  
UK Shrestha ◽  
VM Alurkar ◽  
A Maskey ◽  
M Parajuli ◽  
...  

The global program to eliminate Lymphatic Filariasis created by The World Health organization in 1997 is based on mass administration of single annual doses of diethylcarbamazine ( DEC) plus albendazole in non African regions and of albendazole plus ivermectin in Africa. The usual side effects of DEC treatment include fever, chills, arthralgia, headaches, nausea, and vomiting. Albendazole is associated with relatively few side effects consisting of occasional nausea, vomiting, abdominal pain, headache, reversible alopecia, elevated aminotransferases and rarely leucopenia and rash. We report a case of polyneuropathy in a young individual following DEC and albendazole during mass drug administration. Keywords: Albendazole; DEC; Polyneuropathy. DOI: http://dx.doi.org/10.3126/njms.v1i1.5800   Nepal Journal of Medical Sciences. 2012; 1(1): 56-58


2018 ◽  
Vol 48 (3) ◽  
pp. 232-234
Author(s):  
Om Dawani ◽  
Raja Samir Khan ◽  
Mujtaba Jamal Syed ◽  
Abdul Moid Shehzad ◽  
Ahmed Alratoot ◽  
...  

For many years, tuberculosis (TB) has been endemic in Pakistan; many rare and unusual presentations have been reported. There is a myriad of non-specific symptoms which always requires a high index of clinical suspicion for TB. World Health Organization data suggest that Pakistan ranks as the fifth highest country burdened with TB and has the fourth highest prevalence of multi-drug resistant TB globally. With an annual incidence of 277 cases per 100,000, the importance of early diagnosis and treatment is self-evident. We present a case where a strong suspicion of isolated hepatosplenic TB in an immunocompetent patient justified a directed approach.


Author(s):  
Magboul S

Background: World Health Organization (WHO) and other Health officials alert clinicians about a rare but severe inflammatory condition seen in children and linked to Corona Virus Disease 2019(COVID-19). The WHO is describing the condition as a multisystem inflammatory syndrome in children (MIS-C) and is recommending clinicians to report those cases to get a better understanding of the disease and clinicians can learn more. Case Presentation: We are reporting the clinical course of the youngest case of COVID-19 related MIS-c; a two-week-old term neonate with COVID-19 infection and features suggestive of MIS-C, managed with intravenous immunoglobulin (IVIG), pulse steroid, and interleukin-1 inhibitor (Anakinra). By reviewing the literature, our baby is the first neonatal case who has been diagnosed with MIS-C. Conclusion: COVID-19 infections in pediatrics are likely to present with a mild course; however, some may develop a hyperinflammatory syndrome. Pediatricians should be aware of such presentation, the clinical course, the management modalities,and inform parents and caregivers about common signs and symptoms. Anakinra may consider as effective second agent in (IVIG and steroid-refractory pediatric cases).


2020 ◽  
Author(s):  
Serge ZIGABE ◽  
Etienne Kajibwami ◽  
Guy-Quesney Mateso ◽  
Benjamin Ntaligeza

Abstract COVID-19 started as a cluster of pneumonia cases in Wuhan City, the Province of Hubei, China, in December 2019. It spread to many regions of China, outside of China and was declared a pandemic by the World Health Organization (WHO) on March 11th, 2020. Initially Africa had no case and now the continent is reporting an increasing number of confirmed cases in an exponential manner (1,2).


2021 ◽  
Vol 11 (2-S) ◽  
pp. 1-3
Author(s):  
A Otljanski ◽  
K Kipevska

In 2019 year the world was attacked with corona virus (SARS-CoV-2) and in march 2020, the World Health Organization (WHO) declared the COVID-19 outbreak a pandemic.The symptoms and clinical state in this COVID-19 infection was different, from asymptomatic to mild and severe symptoms, which presented different form of disease: mild, moderate or severe, with or without complications. We presented case with COVID 19 pneumonia as one of the form of COVID infection, with diagnosis, treatment and all investigations we done in our hospital. With complex treatment of this virus infection we successful improved the clinical state of patients with COVID 19 pneumonia. Keywords: coronavirus, SARS-CoV-2, COVID-19, COVID 19 pneumonia


2018 ◽  
Vol 26 (6) ◽  
pp. 375-378
Author(s):  
Sang-Kyoon Han ◽  
Seok-Ran Yeom ◽  
Sung-Hwa Lee ◽  
Soon-Chang Park ◽  
Hyung-Bin Kim ◽  
...  

Introduction: Chlorfenapyr is a pyrrole-based pro-insecticide. The main activity of this agent is the inhibition of adenosine triphosphate synthesis, and it is used in agriculture to control several insects and mites resistant to carbamate, organophosphate and pyrethroid insecticide. The World Health Organization classifies this agent as a class II toxin (moderately hazardous). Case presentation: All previously reported cases of chlorfenapyr poisoning in humans occurred following oral ingestion except one case involving exposure to chlorfenapyr vapour. Discussion: In this report, we describe a case of chlorfenapyr intoxication after skin exposure in a 49-year-old patient who died 5 days after exposure. Conclusion: This case demonstrates that similar to oral ingestion, dermal absorption of chlorfenapyr may also be fatal.


2017 ◽  
Vol 3 (1) ◽  
pp. 1
Author(s):  
Pompini Agustina ◽  
Huda Rahmawati ◽  
Adria Rusli ◽  
Titi Sundari ◽  
Ida Bagus Sila Wiweka

AbstrakLatar belakang : Tuberkulosis (TB) adalah penyakit infeksi yang disebabkan Mycobacterium tuberculosis terutama menyerang paru. Laporan World Health Organization (WHO) menuliskan pada umumnya hanya sedikit orang yang terinfeksi TB menjadi sakit TB namun pada orang dengan HIV/AIDS yang terinfeksi TB banyak menjadi sakit TB. Resistensi terhadap Obat Anti Tuberkulosa (OAT) menjadi salah satu masalah penting dalam pengobatan TB. Ketersediaan obat yang ampuh tetapi tidak diberikan dengan baik menimbulkan masalah resistensi termasuk Resistensi Ganda (RG)/ Multidrug Resistant (MDR).Metode : Penelitian ini mempunyai desain deskriptif potong lintang menggunakan data yang sudah direkapitulasi dari case report form (CRF). Sampel penelitian ini adalah pasien suspek resistensi ganda TB pada HIV. Kriteria inklusi adalah semua pasien usia > 15 tahun dengan HIV TB Paru BTA positif atau negatif kasus baru, kasus kambuh, kasus putus obat, gagal terapi (suspek resistensi ganda) yang berobat ke Instalasi rawat jalan maupun Instalasi rawat inap RSPI Prof Dr. Sulianti Saroso. Sampel berjumlah 21 orang pasien suspek resistensi ganda TB HIV/AIDS periode Maret – Desember 2012 di RSPI Prof dr Sulianti Saroso. Hasil disajikan ke dalam bentuk tabel distribusi frekuensi kemudian dianalisis secara univariat.Hasil : Secara keseluruhan kelompok pasien suspek resistensi ganda TB HIV/AIDS paling banyak didapatkan pada usia 15-35 tahun sebesar 18 orang (85,7%), sebanyak 7 orang (33,33%) bekerja dengan pekerjaan sebagai karyawan, tingkat pendidikan paling banyak Sekolah Menengah Atas berjumlah 15 orang (71,4%) dan faktor risiko pasien paling banyak dari seks bebas dengan jumlah 13 orang (61,9%), Hasil pemeriksaan laboratorium menunjukkan jumlah CD4 pasien cenderung rendah yaitu CD4 <100 sel/μL berjumlah 18 orang (66,7%), sementara jumlah limfosit paling banyak antara 15 % sampai 40 % sebanyak 10 orang (47,6%).Kesimpulan : Profil pasien suspek resistensi ganda TB HIV/AIDS RSPI Prof dr Sulianti Saroso pada kelompok usia produktif dengan faktor risiko utama adalah seks bebas dan kondisi sistem kekebalan tubuh buruk.


2021 ◽  
Vol 9 (03) ◽  
pp. 607-611
Author(s):  
Khalloufi C. ◽  
◽  
Ibnoulkhatib S. ◽  
El Kebir A. ◽  
Karkouri M. ◽  
...  

The debate persists about the inflammatory or tumoral, benign or malignant nature of the Inflammatory myofibroblastic tumors (TMI). Radioclinically, they can mimic a malignant neoplasm, although they are classified as intermediate by the World Health Organization (WHO). The diagnosis is almost always made by pathological examination. The treatment is poorly codified but the management is usually surgical. The removal of these tumors is a challenge when the mass is developed at the expense of or in the vicinity of noble organs. Several therapies have been tested to overcome the limitations of surgery, the results are variable. These tumors rarely affect the digestive tract. We propose the study of a case of myofibroblastic tumor developed at the expense of the omentum, five months after a cesarean section, in order to try to determine if it is a rare complication of the postpartum or a fortuitous combination.


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