scholarly journals Prevalence of HIV Infection Among Foreign Applicant to Residency in Shanghai, China, 2005-2016

2020 ◽  
Author(s):  
Jia Qin ◽  
Jing Xia ◽  
Peiqin Zhu ◽  
Ru Zhou

Abstract Background: Shanghai is an international city which has high proportion of entry travelers from all over the world. The HIV infection status of this population can reflect the global trend of HIV prevalence. Thus, a retrospective epidemic investigation was conducted to clarify the prevalence and characteristics of HIV infection among entry travelers who apply to residency in Shanghai. Methods: Totally 50830 entry travelers who applied to residency in Shanghai(2005-2016)were included. The HIV infection rate was confirmed based on the detection of HIV-1 antibody. Results: Among all the recruited entry travelers, 245 persons were determined HIV positive with infection rate of 0.48%. The detection rate of HIV in male was significantly higher than that in female (χ2=62.584, P<0.0001). Those aged 18-30 years, 31-40 years and >40years accounted for 34.3%, 39.6% and 26.1% of the infected population. There was no increase in trend of HIV prevalence rates among the sampling years (Cochran-Armitage Z=2.543, P=0.111). Proportions of individuals infected through homosexual transmission increased over the study period (Cochran-Armitage Z=5.41, P<0.001), while the proportion infected through heterosexual declined over time (Cochran-Armitage Z=3.38, P =0.001). Conclusion: The characteristics of HIV infection among foreign applicant to residency in Shanghai were clarified. The results would provide the necessary epidemiological data for monitoring the HIV epidemic among entry international travelers and contribute to the establishment of relevant policies and regulations for HIV control and prevention.

2020 ◽  
Author(s):  
Jia Qin ◽  
Jing Xia ◽  
Peiqin Zhu ◽  
Ru Zhou

Abstract Background Shanghai is an international city which has high proportion of entry travelers from all over the world. The HIV(human immunodeficiency virus)infection status of this population can reflect the global trend of HIV prevalence. Thus, a retrospective epidemic investigation was conducted to clarify the prevalence and characteristics of HIV infection among entry travelers who apply to residency in Shanghai. Methods Totally 50830 entry travelers who applied to residency in Shanghai(2005-2016)were included. The HIV infection rate was confirmed based on the detection of HIV-1 antibody. Results Among all the recruited entry travelers, 245 persons were determined HIV positive with infection rate of 0.48%. The detection rate of HIV in male was significantly higher than that in female (χ 2 =62.584, P <0.0001). Those aged 18-30 years, 31-40 years and >40years accounted for 34.3%, 39.6% and 26.1% of the infected population. There was no increase in trend of HIV prevalence rates among the sampling years (Cochran-Armitage Z=2.543, P=0.111). Proportions of individuals infected through homosexual transmission increased over the study period (Cochran-Armitage Z=5.41, P<0.001), while the proportion infected through heterosexual declined over time (Cochran-Armitage Z=3.38, P =0.001). Conclusion The rate and characteristics of HIV infection among foreign applicant to residency in Shanghai were clarified in the study. The results would have provided the necessary epidemiological data for monitoring the HIV epidemic among entry international travelers and to further contribute to the establishment of relevant policies and regulations for HIV control and prevention.


2019 ◽  
Author(s):  
Jia Qin ◽  
Ru Zhou ◽  
Jing Xia ◽  
Weixin Wang ◽  
Jun Pan ◽  
...  

AbstractBackgroundShanghai is one of the biggest cities which have the highest number of entry travelers from all over the world. The HIV(human immunodeficiency virus) infection status of this population can reflect global trends of HIV prevalence to a certain extent.MethodsA retrospective cohort study was conducted to reveal the prevalence and characteristics of HIV-1 infection among entry travelers who applied to residency in Shanghai. The HIV-1 infection rate was estimated based on the detection of HIV-1 antibody.ResultsAmong 50830 entry travelers who applied to residency in Shanghai(2005-2016), 245 were determined HIV-1 positive with an infection rate of 0.48%. The detection rate of HIV was significantly higher in male (P<0.0001). Those aged 18-30 years, 31-40 years and >40years accounted for 34.3%,39.6% and 26.1% respectively of the infected population. Although there was no trend of increase in HIV-1 prevalence rates (Cochran-Armitage Z =2.543, P =0.111),proportions of individuals infected through homosexual transmission increased over the study period (Cochran-Armitage Z =5.41, P<0.001), while the proportions infected through heterosexual(Cochran-Armitage Z=3.38, P=0.001).ConclusionThe rate and characteristics of HIV-1 infection among foreign applicant to residency in Shanghai were revealed in the study. The results could provide the necessary epidemiological data for monitoring the HIV-1 epidemic among entry international travelers and to further contribute to the establishment of relevant policies and regulations for HIV control and prevention.


2018 ◽  
Vol 16 (2) ◽  
pp. 174-181 ◽  
Author(s):  
Yunxiao Lei ◽  
Kaili Zhang ◽  
Xueling Xiao ◽  
Chulei Tang ◽  
Xianhong Li ◽  
...  

Background: HIV infection is prevalent among men who have sex with men (MSM), and sexual roles may be important factors related to it. This study aims to describe the sexual roles, risky sexual behaviors and HIV prevalence among MSM, and to determine associated factors for HIV prevalence. Methods: A convenient sampling method was used to recruit participants in a non-government organization in Changsha, China. The participants were asked to complete a 38-item self-administered questionnaire regarding demographic characteristics and risky sexual behaviours before collecting blood samples for HIV testing. Chi-square tests and logistic regression analysis were conducted with the Statistical Package for the Social Sciences Version 18.0 and other indexes were statistically described. Results: A total of 601 MSMs who came to a local non-government organization for voluntary counseling and testing completed a pencil-and-paper survey and were tested for HIV. The overall HIV prevalence of this sample was 13.3%, and that of the bottoms (16.3%) was similar to the versatiles (15.9%) but higher than the tops (6.1%). Bivariate analyses showed that there were significant differences in age, marital status, monthly income, sexual orientation, age at first sex, sex of the first sex partner, sex with a woman in the last 6 months, oral sex with a man in the last 6 months and role of oral sex among 3 subgroups of MSM (p < 0.05). Multivariate analyses indicated that MSMs who played the role of either the bottoms or the versatiles were more likely to be HIV positive than the tops. While MSMs who used condoms in anal sex in the last 6 months, had sex with a woman in the last 6 months or had oral sex with a man in the last 6 months were less likely to be HIV positive. Conclusion: Different sexual roles are associated with high-risk sexual behaviors among MSMs and their HIV infection status. Further research should target preventive interventions, and improve the effectiveness of the intervention according to the characteristics of the subgroups to reduce the HIV transmission among Chinese MSM.


Author(s):  
Ren-Zong QIU

LANGUAGE NOTE | Document text in Chinese; abstract also in English.本文討論了艾滋病在中國大陸傳播引起的倫理和政策問題。作者首先指出在預防控制艾滋病問題上中國正處在十字路口。挨著作者分析了中國會不會成為艾滋病和艾滋病病毒感染的高發國,討論了制訂有效而合乎倫理的艾滋病防治政策的理論預設和價值以及評價政策的倫理學框架,討論了艾滋病治療和預防中的倫理和政策問題。The AIDS/HIV prevention and control in China is at crossroad. At present, there are insufficient grounds for us to say that China will definitely become a country with a high HIV infection rate in the future. However, we have much less sufficient grounds for saying that China will never reach that stage. On the contrary, we have much more reason to say that it is very probable for China to become a country with high HIV infection rate if we leave the current policy unchanged. The reasons are: economic reforms associated with large scale population movements in unprecedented way; proliferation of all sorts of high risk behavior, presence of other STDs which facilitate the spread of HIV; the risk of iatrogenic spread through untested blood transfusion; the "sex revolution" with changes in patterns of sex behaviour and increased casual sex, multiple sex partners among the younger generation; most Chinese still do not know how to protect themselves; and the ethical and legal atmosphere necessary for effectively preventing the HIV epidemic has not been formed.The conventional public health approach is not sufficient to prevent or control an HIV epidemic. When the cases of HIV infection were detected one by one in China, health professionals and programmers believed that they could take a conventional public health approach to cope with HIV epidemic. But they are wrong. HIV infection is an epidemic so special that the conventional public health measures such as testing, reporting, contact tracing, isolation are inadequate or ineffective to control the epidemic. HIV is often spread among those groups who are usually marginalized or stigmatized by society through behaviours both confidential or private.An effective policy of preventing HIV cannot be insensitive to ethical issues. However, many of health professionals and programmers bypassed ethical issues emerged in the prevention of the HIV epidemic. Even some health educators, sexologists and officials believe that "AIDS is the punishment by God" or "AIDS is the punishment for promiscuity". For them suffering AIDS is not morally irrelevant, and thus the ancient conception of disease was revived. But this conception of disease has already proved wrong and harmful to the treatment and prevention of any disease, especially to HIV. The consequence entailed by this conception is that the IIIV positive and AIDS patients were discriminated against and stigmatized. When their positive serological status was disclosed, they were faced with the risk of being expelled from school or fired from working unit, even rejected for admission into hospital, and their tights to confidentiality and privacy were often infringed upon. If all these ethical issues cannot be properly treated, how can those persons in danger or risk get access to information, services, education, counselling and techniques necessary to prevent HIV infection? One Chinese adage says that "You cannot have fish and bear palm both". In the prevention of HIV epidemic we have to have the protection of public health and the safeguarding of individual rights.For controlling HIV epidemic what we need is not a repressive law, but a supportive law to build a supportive environment in treatment and prevention of AIDS/HIV. So the policy and law involving AIDS/ HIV should be reformed.DOWNLOAD HISTORY | This article has been downloaded 19 times in Digital Commons before migrating into this platform.


1997 ◽  
Vol 27 (1) ◽  
pp. 43-56
Author(s):  
Roger Lewis

Since 1983 parts of Scotland, unlike England, have experienced a major drug-related HIV epidemic. Edinburgh and Lothian currently have a known HIV-infected population of 1,105. A variety of harm-reduction measures, including needle exchanges, methadone prescription, community drug agencies, and targeted prevention campaigns have been implemented since 1985. The number of drug-related HIV infections reported has fallen significantly since 1988. However, sexual transmission remains a cause for concern, particularly among the injecting and non-injecting partners of HIV-positive drug users.


Retrovirology ◽  
2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Samantha McInally ◽  
Kristin Wall ◽  
Tianwei Yu ◽  
Rabindra Tirouvanziam ◽  
William Kilembe ◽  
...  

Abstract Background To determine if individuals, from HIV-1 serodiscordant couple cohorts from Rwanda and Zambia, who become HIV-positive have a distinct inflammatory biomarker profile compared to individuals who remain HIV-negative, we compared levels of biomarkers in plasma of HIV-negative individuals who either seroconverted (pre-infection) and became HIV-positive or remained HIV-negative (uninfected). Results We observed that individuals in the combined cohort, as well as those in the individual country cohorts, who later became HIV-1 infected had significantly higher baseline levels of multiple inflammatory cytokines/chemokines compared to individuals who remained HIV-negative. Genital inflammation/ulceration or schistosome infections were not associated with this elevated profile. Defined levels of ITAC and IL-7 were significant predictors of later HIV acquisition in ROC predictive analyses, whereas the classical Th1 and Th2 inflammatory cytokines such as IL-12 and interferon-γ or IL-4, IL-5 and Il-13 were not. Conclusions Overall, the data show a significant association between increased plasma biomarkers linked to inflammation and immune activation and HIV acquisition and suggests that pre-existing conditions that increase systemic biomarkers represent a factor for increased risk of HIV infection.


2021 ◽  
Vol 50 (Supplement_1) ◽  
Author(s):  
Jabulani Ncayiyana ◽  
Griffin Bell ◽  
Ari Solomon ◽  
Micheal Emch

Abstract Background South Africa has a high HIV prevalence and generalized HIV epidemic. It is now well established that the HIV epidemic and its drivers are highly heterogeneous, even in generalized HIV epidemic settings. Methods This study uses data from South African HIV/AIDS, Behavioural Risks, Sero-status, and Mass Media Impact (SABSSM), 2005, 2008 and 2012 surveys. To identify spatial clusters, we used the spatial scan statistic method in SaTScan, assuming discrete Poisson distributions. Poisson regression models were used to explore the municipality-level correlates of HIV prevalence and a logistic regression model was used to determine individual-level correlates of HIV infection. Results Between 2005 and 2012, There was significant geographical variation in estimated HIV prevalence (range = &lt;1.0%–27.5%). Eight, five and six significant overlapping high-risk spatial clusters of high HIV prevalence were detected in 2005, 2008 and 2012, respectively. HIV prevalence is clustered in the central and north-eastern regions of South Africa. Living in municipalities with high percentage of black South Africans, higher poverty index, higher population aged 25-49, and higher early sexual debut were associated with HIV prevalence, while living in municipalities with higher percentage male circumcision and a high percentage married were associated with low risk of HIV. Logistic regression revealed race, sex and mobility as correlates of HIV infection. Conclusions HIV prevalence is highly spatially heterogenous and affected by various municipal-level factors. Key messages Identification of the spatial clusters of HIV prevalence and contextual factors should inform targeted interventions that are necessary to bringing HIV infections under control.


2021 ◽  
Vol 20 (5) ◽  
pp. 98-106
Author(s):  
E. N. Mel`nikova ◽  
A. N. Marchenko

Relevance. The geographical spread of HIV infection among the population of various administrative territories is very heterogeneous. The Tyumen region, due to its vast territory and the significant remoteness of some areas from the regional center, is of particular interest in the framework of considering the territorial features of the spread of HIV.Aims. To consider peculiarities of the spread of hiv infection among urban and rural residents of the Tyumen region in 1993–2019.Materials & Methods. Statistical data of the «Center for the Prevention and Control of AIDS» in the period from 1993 to 2019, annual form No. 61 «Information on the contingents of HIV patients» for 2006–2019, materials of the state report «On the sanitary and epidemiological situation in the Tyumen region» for 2013–2019. Methods of epidemiological observation were used in the work: analytical and descriptive-evaluative with the use of methods of retrospective and operational analysis and statistical methods.Results and Discussions. A specific feature of the spread of HIV infection among urban and rural residents is the tendency to exceed the regional incidence rate in a number of territories. Analysis of epidemiological data for the period under review showed that all territories of the region are involved in the epidemiological process of HIV infection, and in a number of territories the prevalence rate exceeds the average Russian level. HIV prevalence as of December 31, 2019 was 728.2 per 100 thousand people in Russia. In 17 administrative territories of the Tyumen region the infection rate is higher than the national average level and is per 100 thousand population in the city of Tobolsk – 1903.3, in the districts of Uvat – 1486.2, Tobolsk – 1440.5, Nizhnetavda – 1354.9, Tyumen – 1344.1, Yalutorovsk – 1327.6), in the city. Tyumen – 1249.3, in the districts: Vagay – 1195.2, Zavodoukovsky – 1119.2, in Ishim – 951.8, in the districts: Yarkovsky – 889.6, Vikulovsky – 881.3, Yurginsky – 846.9, Ishimsky district – 842.1, Aromashevsky – 851.6, Isetovsky – 754.4, Uporovsky district – 734.7.Conclusions. The HIV epidemic in the Tyumen region is determined by its economic and geographic location and by the presence of exceptional epidemiologically significant prerequisites for the intensive spread of HIV, in particular, by the routes through which large quantities of drugs are illegally transported (drug trafficking from the northeast).


PLoS ONE ◽  
2020 ◽  
Vol 15 (11) ◽  
pp. e0242281
Author(s):  
Carol Lin ◽  
Isabelle Casavant ◽  
Alicia Jaramillo ◽  
Timothy Green

Background HIV prevalence in Mozambique (12.6%) is one of the highest in the world, yet ~40% of people living with HIV (PLHIV) do not know their HIV status. Strategies to increase HIV testing uptake and diagnosis among PLHIV are urgently needed. Home-based HIV testing services (HBHTS) have been evaluated primarily as a 1-time campaign strategy. Little is known about the potential of repeating HBHTS to diagnose HIV infection among persons who have never been tested (NTs), nor about factors/reasons associated with never testing in a generalized epidemic setting. Methods During 2014–2017, counselors visited all households annually in the Chókwè Health and Demographic Surveillance System (CHDSS) and offered HBHTS. Cross-sectional surveys were administered to randomly selected 10% or 20% samples of CHDSS households with participants aged 15–59 years before HBHTS were conducted during the visit. Descriptive statistics and logistic regression were used to assess the proportion of NTs, factors/reasons associated with never having been tested, HBHTS acceptance, and HIV-positive diagnosis among NTs. Results The proportion of NTs decreased from 25% (95% confidence interval [CI]:23%–26%) during 2014 to 12% (95% CI:11% –13%), 7% (95% CI:6%–8%), and 7% (95% CI:6%–8%) during 2015, 2016, and 2017, respectively. Adolescent boys and girls and adult men were more likely than adult women to be NTs. In each of the four years, the majority of NTs (87%–90%) accepted HBHTS. HIV-positive yield among NTs subsequently accepting HBHTS was highest (13%, 95% CI:10%–15%) during 2014 and gradually reduced to 11% (95% CI:8%–15%), 9% (95% CI:6%–12%), and 2% (95% CI:0%–4%) during 2015, 2016, and 2017, respectively. Conclusions Repeated HBHTS was helpful in increasing HIV testing coverage and identifying PLHIV in Chókwè. In high HIV-prevalence settings with low testing coverage, repeated HBHTS can be considered to increase HIV testing uptake and diagnosis among NTs.


Author(s):  
Prerna Kataria ◽  
Kriti Aggarwal

HIV infection is global health problem of unprecedented dimensions. Periodontal diseases are associated with HIV infection and involvement has been suspected specifically for HIV virus. Reports of increased prevalence of chronic periodontitis in HIV-positive subjects suggest that HIV infection predispose to Periodontitis. But on the contrary, current literature suggests that the course of HIV infection is also modified by the periodontal conditions. Research needs to be done regarding the HIV infection and periodontal health inter-relationship, as it can help in better understanding and treatment by the Periodontist.


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